SG11201805941WA - Tgfbeta 2 antibodies - Google Patents

Tgfbeta 2 antibodies

Info

Publication number
SG11201805941WA
SG11201805941WA SG11201805941WA SG11201805941WA SG11201805941WA SG 11201805941W A SG11201805941W A SG 11201805941WA SG 11201805941W A SG11201805941W A SG 11201805941WA SG 11201805941W A SG11201805941W A SG 11201805941WA SG 11201805941W A SG11201805941W A SG 11201805941WA
Authority
SG
Singapore
Prior art keywords
novartis
international
tgf
massachusetts
antibodies
Prior art date
Application number
SG11201805941WA
Other languages
English (en)
Inventor
Chikwendu Ibebunjo
Carsten Jacobi
Angelika Meyer
Eveline Schaadt
Anne-Ulrike Trendelenburg
Mitina Olga Vladimirovna
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58191507&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201805941W(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SG11201805941WA publication Critical patent/SG11201805941WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201805941WA 2016-02-17 2017-02-17 Tgfbeta 2 antibodies SG11201805941WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662296282P 2016-02-17 2016-02-17
PCT/IB2017/050917 WO2017141208A1 (fr) 2016-02-17 2017-02-17 Anticorps anti-tgfbêta 2

Publications (1)

Publication Number Publication Date
SG11201805941WA true SG11201805941WA (en) 2018-09-27

Family

ID=58191507

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201805941WA SG11201805941WA (en) 2016-02-17 2017-02-17 Tgfbeta 2 antibodies

Country Status (21)

Country Link
US (1) US11180546B2 (fr)
EP (1) EP3416982A1 (fr)
JP (1) JP2019511911A (fr)
KR (1) KR20180107151A (fr)
CN (1) CN108699142A (fr)
AU (1) AU2017219254B2 (fr)
BR (1) BR112018015690A2 (fr)
CA (1) CA3012294A1 (fr)
CL (1) CL2018001941A1 (fr)
CO (1) CO2018008590A2 (fr)
CU (1) CU20180088A7 (fr)
EA (1) EA201891724A1 (fr)
EC (1) ECSP18064646A (fr)
HK (1) HK1257455A1 (fr)
IL (1) IL261065A (fr)
MA (1) MA44236A (fr)
MX (1) MX2018010021A (fr)
PH (1) PH12018501525A1 (fr)
RU (1) RU2018131123A (fr)
SG (1) SG11201805941WA (fr)
WO (1) WO2017141208A1 (fr)

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EP4007774A1 (fr) 2019-08-01 2022-06-08 Vaccinex, Inc. Inhibition combinée de sémaphorine-4d et tgfb, et compositions associées
AU2021236660A1 (en) 2020-03-19 2022-08-18 Genentech, Inc. Isoform-selective anti-TGF-beta antibodies and methods of use
AU2022219373A1 (en) 2021-02-15 2023-08-24 Takeda Pharmaceutical Company Limited Cell therapy compositions and methods for modulating tgf-b signaling
CN112940119B (zh) * 2021-04-26 2022-05-20 北京芳渟阳生生物科技有限公司 一种单克隆抗体及其与间充质干细胞外泌体的联合应用
WO2023201310A1 (fr) 2022-04-13 2023-10-19 HCW Biologics, Inc. Polypeptide chimérique à chaînes multiples destiné à être utilisé dans le traitement d'un trouble de gènes de l'horloge circardienne
WO2023201311A1 (fr) 2022-04-13 2023-10-19 HCW Biologics, Inc. Polypeptide chimérique à chaînes multiples destiné à être utilisé dans le traitement d'un trouble neuro-inflammatoire

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Also Published As

Publication number Publication date
HK1257455A1 (zh) 2019-10-18
KR20180107151A (ko) 2018-10-01
PH12018501525A1 (en) 2019-03-18
EP3416982A1 (fr) 2018-12-26
JP2019511911A (ja) 2019-05-09
RU2018131123A3 (fr) 2020-07-09
RU2018131123A (ru) 2020-03-17
WO2017141208A1 (fr) 2017-08-24
CU20180088A7 (es) 2019-05-03
CA3012294A1 (fr) 2017-08-24
ECSP18064646A (es) 2018-09-30
BR112018015690A2 (pt) 2018-12-26
US20190092846A1 (en) 2019-03-28
CN108699142A (zh) 2018-10-23
CL2018001941A1 (es) 2018-09-07
MA44236A (fr) 2018-12-26
CO2018008590A2 (es) 2018-08-21
MX2018010021A (es) 2018-11-09
EA201891724A1 (ru) 2019-01-31
US11180546B2 (en) 2021-11-23
AU2017219254A1 (en) 2018-08-02
AU2017219254B2 (en) 2019-12-12
IL261065A (en) 2018-10-31

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