SG11201804360XA - Mat2a inhibitors for treating mtap null cancer - Google Patents
Mat2a inhibitors for treating mtap null cancerInfo
- Publication number
- SG11201804360XA SG11201804360XA SG11201804360XA SG11201804360XA SG11201804360XA SG 11201804360X A SG11201804360X A SG 11201804360XA SG 11201804360X A SG11201804360X A SG 11201804360XA SG 11201804360X A SG11201804360X A SG 11201804360XA SG 11201804360X A SG11201804360X A SG 11201804360XA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- mat2a
- mtap
- massachusetts
- publication
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/02—Halogenated hydrocarbons
- A61K31/025—Halogenated hydrocarbons carbocyclic
- A61K31/03—Halogenated hydrocarbons carbocyclic aromatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562262750P | 2015-12-03 | 2015-12-03 | |
US201662297572P | 2016-02-19 | 2016-02-19 | |
PCT/US2016/064619 WO2017096165A1 (en) | 2015-12-03 | 2016-12-02 | Mat2a inhibitors for treating mtap null cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201804360XA true SG11201804360XA (en) | 2018-06-28 |
Family
ID=57614465
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201804360XA SG11201804360XA (en) | 2015-12-03 | 2016-12-02 | Mat2a inhibitors for treating mtap null cancer |
Country Status (12)
Country | Link |
---|---|
US (1) | US20180371551A1 (he) |
EP (1) | EP3383375A1 (he) |
JP (2) | JP6877429B2 (he) |
KR (1) | KR20180100125A (he) |
CN (1) | CN108601752A (he) |
AU (1) | AU2016364855B2 (he) |
CA (1) | CA3006743A1 (he) |
EA (1) | EA201891304A1 (he) |
IL (1) | IL259773A (he) |
MX (1) | MX2018006781A (he) |
SG (1) | SG11201804360XA (he) |
WO (1) | WO2017096165A1 (he) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2743463C2 (ru) | 2012-05-30 | 2021-02-18 | Чугаи Сейяку Кабусики Кайся | Специфичная к ткани-мишени антигенсвязывающая молекула |
EP3763813A1 (en) | 2013-12-04 | 2021-01-13 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecules, the antigen-binding activity of which varies according to the concentration of compounds, and libraries of said molecules |
US11376256B2 (en) | 2018-07-19 | 2022-07-05 | Agency For Science, Technology And Research | Method of treating a methionine-dependent cancer |
EP3894396A1 (en) | 2018-12-10 | 2021-10-20 | Ideaya Biosciences, Inc. | 2-oxoquinazoline derivatives as methionine adenosyltransferase 2a inhibitors |
EP3943108A4 (en) * | 2019-03-19 | 2023-01-04 | Chugai Seiyaku Kabushiki Kaisha | ANTIGEN-BINDING MOLECULE CONTAINING AN ANTIGEN-BINDING DOMAIN WHOSE ANTIGEN-BINDING ACTIVITY IS ALTERED DEPENDING ON THE MTA, AND BANK FOR OBTAINING SUCH ANTIGEN-BINDING DOMAIN |
WO2021023609A1 (en) * | 2019-08-02 | 2021-02-11 | Glaxosmithkline Intellectual Property Development Limited | Combination of a type i protein arginine methyltransferase (type i prmt) inhibitor and a methionine adenosyltransferase ii alpha (mat2a) inhibitor |
WO2021158792A1 (en) * | 2020-02-04 | 2021-08-12 | Agios Pharmaceuticals, Inc. | Methods of treating autoimmune or inflammatory diseases or disorders |
CN113999232A (zh) * | 2020-07-28 | 2022-02-01 | 南京正大天晴制药有限公司 | Mat2a抑制剂 |
WO2022036067A1 (en) * | 2020-08-12 | 2022-02-17 | Servier Pharmaceuticals, Llc | Combination therapies for use in treating cancer |
JP2024521920A (ja) * | 2021-06-02 | 2024-06-04 | アイディアヤ バイオサイエンシーズ,インコーポレイティド | Mat2a阻害剤及びii型prmt阻害剤を含む併用療法 |
CN113476450B (zh) * | 2021-08-10 | 2023-04-28 | 江南大学 | Epz015666在制备用于防治血管内膜增生类疾病的药物中的应用 |
CN114028572B (zh) * | 2021-11-30 | 2022-11-25 | 清华大学 | Mat2a抑制剂用于治疗哮喘的新应用 |
KR20240051860A (ko) | 2022-10-13 | 2024-04-22 | 한미약품 주식회사 | 신규한 트리사이클 유도체 화합물 및 이의 용도 |
CN115825214A (zh) * | 2022-11-30 | 2023-03-21 | 厦门大学 | 一种基于MALDI-TOF-MS体外筛选hMAT2A蛋白抑制剂的方法及其应用 |
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-
2016
- 2016-12-02 EA EA201891304A patent/EA201891304A1/ru unknown
- 2016-12-02 JP JP2018528729A patent/JP6877429B2/ja active Active
- 2016-12-02 WO PCT/US2016/064619 patent/WO2017096165A1/en active Application Filing
- 2016-12-02 CN CN201680080863.1A patent/CN108601752A/zh active Pending
- 2016-12-02 AU AU2016364855A patent/AU2016364855B2/en active Active
- 2016-12-02 CA CA3006743A patent/CA3006743A1/en not_active Abandoned
- 2016-12-02 SG SG11201804360XA patent/SG11201804360XA/en unknown
- 2016-12-02 US US15/780,494 patent/US20180371551A1/en not_active Abandoned
- 2016-12-02 MX MX2018006781A patent/MX2018006781A/es unknown
- 2016-12-02 KR KR1020187018814A patent/KR20180100125A/ko not_active Application Discontinuation
- 2016-12-02 EP EP16819232.6A patent/EP3383375A1/en not_active Withdrawn
-
2018
- 2018-06-03 IL IL259773A patent/IL259773A/he unknown
-
2021
- 2021-03-10 JP JP2021037941A patent/JP2021098736A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2018537473A (ja) | 2018-12-20 |
EA201891304A1 (ru) | 2019-01-31 |
AU2016364855B2 (en) | 2019-08-29 |
IL259773A (he) | 2018-07-31 |
WO2017096165A1 (en) | 2017-06-08 |
US20180371551A1 (en) | 2018-12-27 |
MX2018006781A (es) | 2018-11-09 |
JP6877429B2 (ja) | 2021-05-26 |
CN108601752A (zh) | 2018-09-28 |
EP3383375A1 (en) | 2018-10-10 |
CA3006743A1 (en) | 2017-06-08 |
AU2016364855A1 (en) | 2018-07-05 |
KR20180100125A (ko) | 2018-09-07 |
JP2021098736A (ja) | 2021-07-01 |
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