SG11201705953XA - Use of short chain fatty acids in cancer prevention - Google Patents

Use of short chain fatty acids in cancer prevention

Info

Publication number
SG11201705953XA
SG11201705953XA SG11201705953XA SG11201705953XA SG11201705953XA SG 11201705953X A SG11201705953X A SG 11201705953XA SG 11201705953X A SG11201705953X A SG 11201705953XA SG 11201705953X A SG11201705953X A SG 11201705953XA SG 11201705953X A SG11201705953X A SG 11201705953XA
Authority
SG
Singapore
Prior art keywords
fatty acids
chain fatty
short chain
cancer prevention
cancer
Prior art date
Application number
SG11201705953XA
Other languages
English (en)
Inventor
Mark A Feitelson
Helena M G P V Reis
Original Assignee
Temple University-Of The Commonwealth System Of Higher Education
Helena M G P V Reis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Temple University-Of The Commonwealth System Of Higher Education, Helena M G P V Reis filed Critical Temple University-Of The Commonwealth System Of Higher Education
Publication of SG11201705953XA publication Critical patent/SG11201705953XA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Non-Alcoholic Beverages (AREA)
SG11201705953XA 2015-01-23 2016-01-21 Use of short chain fatty acids in cancer prevention SG11201705953XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562106778P 2015-01-23 2015-01-23
PCT/US2016/014292 WO2016118730A1 (en) 2015-01-23 2016-01-21 Use of short chain fatty acids in cancer prevention

Publications (1)

Publication Number Publication Date
SG11201705953XA true SG11201705953XA (en) 2017-08-30

Family

ID=56417737

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201705953XA SG11201705953XA (en) 2015-01-23 2016-01-21 Use of short chain fatty acids in cancer prevention
SG10201907660Y SG10201907660YA (en) 2015-01-23 2016-01-21 Use of short chain fatty acids in cancer prevention

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201907660Y SG10201907660YA (en) 2015-01-23 2016-01-21 Use of short chain fatty acids in cancer prevention

Country Status (13)

Country Link
US (5) US10231941B2 (ja)
EP (1) EP3247342A4 (ja)
JP (3) JP6783247B2 (ja)
KR (1) KR20170128247A (ja)
CN (2) CN107405321A (ja)
AU (3) AU2016209244A1 (ja)
CA (1) CA2974510A1 (ja)
IL (1) IL253581A0 (ja)
MX (1) MX2017009532A (ja)
RU (1) RU2017127597A (ja)
SG (2) SG11201705953XA (ja)
WO (1) WO2016118730A1 (ja)
ZA (1) ZA201704977B (ja)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
EP3881680A1 (en) 2014-10-31 2021-09-22 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment
WO2016102951A1 (en) 2014-12-23 2016-06-30 4D Pharma Research Limited Pirin polypeptide and immune modulation
ME02997B (me) 2014-12-23 2018-10-20 4D Pharma Res Ltd Soj bacteroides thetaiotaomicron i njegova upotreba u smanjenju inflamacije
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
CN115364122A (zh) 2015-06-15 2022-11-22 4D制药研究有限公司 包含细菌菌株的组合物
PL3206700T3 (pl) 2015-06-15 2019-11-29 4D Pharma Res Ltd Kompozycje zawierające szczepy bakteryjne
MD3307288T2 (ro) 2015-06-15 2019-12-31 4D Pharma Res Ltd Compoziții care conțin tulpini bacteriene
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
EA034677B1 (ru) 2015-11-20 2020-03-05 4Д Фарма Рисёрч Лимитед Композиции для лечения или профилактики рака, содержащие штамм enterococcus gallinarum
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
DK3313423T3 (da) 2016-03-04 2019-05-20 4D Pharma Plc Sammensætninger omfattende bakterielle blautia-stammer til behandling af visceral hypersensitivitet
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
TWI802545B (zh) 2016-07-13 2023-05-21 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
WO2018089861A1 (en) * 2016-11-11 2018-05-17 The Regents Of The University Of California Methods and compositions for the treatment of cancer and metabolic diseases
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
US11065217B2 (en) 2017-01-27 2021-07-20 Temple University—Of the Commonwealth System of Higher Education Use of short chain fatty acids for the treatment and prevention of diseases and disorders
JP7136807B2 (ja) 2017-04-17 2022-09-13 ザ・ユニバーシティ・オブ・シカゴ ヒトの健康及び疾患の治療用途向けの短鎖脂肪酸の腸への送達用ポリマー材料
LT3630136T (lt) 2017-05-22 2021-06-10 4D Pharma Research Limited Kompozicijos, apimančios bakterines padermes
WO2018215782A1 (en) 2017-05-24 2018-11-29 4D Pharma Research Limited Compositions comprising bacterial strain
IL283973B (en) 2017-06-14 2022-08-01 4D Pharma Res Ltd Preparations containing bacterial strains
EP3638271B1 (en) 2017-06-14 2020-10-14 4D Pharma Research Limited Compositions comprising bacterial strains
HUE052258T2 (hu) 2017-06-14 2021-04-28 4D Pharma Res Ltd Megasphaera nemzetségbe tartozó baktériumtörzset tartalmazó készítmény, és alkalmazása
AU2018298087A1 (en) 2017-07-05 2020-01-23 Evelo Biosciences, Inc. Compositions and methods of treating cancer using bifidobacterium animalis ssp. lactis
BR112019027088A2 (pt) * 2017-08-04 2020-07-07 Société des Produits Nestlé S.A. bactérias probióticas precondicionadas em um meio contendo gos e uso das mesmas
CA3073838A1 (en) 2017-08-30 2019-03-07 Pendulum Therapeutics, Inc. Methods and compositions for treatment of microbiome-associated disorders
CN110090230B (zh) * 2018-01-30 2022-07-12 青岛东海药业有限公司 凝结芽孢杆菌在制备预防或治疗胆管癌制剂中的应用
CN112601534A (zh) * 2018-05-11 2021-04-02 4D制药研究有限公司 包含细菌菌株的组合物
WO2019232513A1 (en) * 2018-06-01 2019-12-05 Evolve Biosystems, Inc. Compositions and methods to promote host defense and stimulate, expand, and/or reset t cell repertoires
US20220364056A1 (en) * 2019-09-25 2022-11-17 Philipps-Universität Marburg Short-chain fatty acid pentanoate as enhancer for cellular therapy and anti-tumor therapy
KR102510198B1 (ko) * 2019-11-14 2023-03-15 가톨릭대학교 산학협력단 락토바실러스 속 균주 및 SCFA(Short fatty chain acid)를 포함하는 면역 질환의 예방 및 치료용 조성물
TWI734341B (zh) * 2020-01-14 2021-07-21 景岳生物科技股份有限公司 一種副乾酪乳桿菌ｇｍｎｌ-３４６用於抗口腔癌之用途
US20230120406A1 (en) * 2020-03-05 2023-04-20 Liscure Biosciences Co., Ltd. Pharmaceutical composition for prevention or treatment of cancer comprising leuconostoc sp. as active ingredient
US20240009154A1 (en) * 2020-08-04 2024-01-11 Temple University-Of The Commonwealth System Of Higher Education Methods and compositions for treating cytokine release syndrome
US11938152B2 (en) 2020-08-06 2024-03-26 Kedar N Prasad High-dose antioxidants in cancer treatment
US20240009155A1 (en) * 2020-11-12 2024-01-11 Temple University-Of The Commonwealth System Of Higher Education Use of short chain fatty acids in cancer prevention
WO2022177409A1 (ko) * 2021-02-22 2022-08-25 주식회사 리스큐어바이오사이언시스 류코노스톡 메센테로이데스 균주 유래 나노소포체를 유효성분으로 포함하는 암의 예방 또는 치료용 약학 조성물
WO2023141202A1 (en) * 2022-01-19 2023-07-27 Hodgdon Ian Short-chain fatty acids for cancer treatment
CN117925434A (zh) * 2022-10-26 2024-04-26 慕恩（广州）生物科技有限公司 粪肠球菌mnh 22871及其应用

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735967A (en) 1985-05-28 1988-04-05 Neesby Torben E Method for desensitizing the gastrointestinal tract from food allergies
AU645070B2 (en) 1990-04-10 1994-01-06 Nb International Technologies Use of short chain fatty acid containing lipids to maintain gastrointestinal integrity and function in patients DO NOT SEAL - SEE LETTER DATED 22.03.94
PH31403A (en) 1991-03-01 1998-10-29 Warner Lambert Co Therapeutic compositions to protect and recuscitate mammalian cells and methods for preparing same.
CA2174737C (en) 1993-10-29 2008-04-22 Douglas V. Faller Physiologically stable compositions of butyric acid, and butyric acid salts and derivatives as anti-neoplastic agents
JP2000072667A (ja) 1998-08-25 2000-03-07 Kurasuraa:Kk 大腸炎治療用経口投与剤
US6201077B1 (en) 1998-12-01 2001-03-13 Phillips Petroleum Company Process that produces polymers
EP1034788A1 (en) 1999-03-11 2000-09-13 Société des Produits Nestlé S.A. Lactic acid bacteria strains capable of preventing diarrhea
JP4360915B2 (ja) 2002-01-07 2009-11-11 ユーロスクリーン・ソシエテ・アノニム Ｇタンパク質共役受容体ｇｐｒ４３のリガンドおよびその使用
ES2532607T3 (es) 2002-03-04 2015-03-30 Merck Hdac Research, Llc Métodos de inducción de la diferenciación terminal
CN100566711C (zh) 2002-04-15 2009-12-09 斯隆-凯特林癌症研究院 治疗癌症的化合物及其用途
US8846039B2 (en) 2002-04-26 2014-09-30 Asan Laboratories Company (Cayman), Limited Method for ameliorating pruritus
AU2003259521A1 (en) 2002-09-13 2004-04-30 Mcguire Va Medical Center 111K Combination of a) n-{5-(4-(4-methyl-piperazino-methyl)-benzoylamido)-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidine-amine and b) a histone deacetylase inhibitor for the treatment of leukemia
US20050023179A1 (en) 2003-07-31 2005-02-03 Albritton Charles Wade Fragile-product cage for vacuum packaging appliances
EP1667680A4 (en) 2003-08-29 2008-10-08 Aton Pharma Inc COMBINED METHODS OF TREATING CANCER
WO2007016955A1 (en) 2005-07-29 2007-02-15 Matuschka-Greiffenclau Markus Alcohol metabolism moderating composition
CA2647986C (en) * 2006-03-31 2014-07-08 Erasmus University Medical Center Rotterdam Compositions for tumor growth control
US20080153908A1 (en) 2006-12-20 2008-06-26 Jani Dharmendra M Method of Treating Mucin Deficiency with an Active Pharmaceutical and Related Composition
JP5468015B2 (ja) 2008-01-08 2014-04-09 アクセリア ファーマシューティカルズ 抗菌ペプチド系に対する作動薬
CN101214234B (zh) * 2008-01-10 2010-09-08 中国人民解放军第二军医大学 α-羟基酸在制备癌瘤体内注射治疗药物中的应用
WO2010095950A1 (en) 2009-02-18 2010-08-26 Sea Qiq As Mixture of inorganic compounds, preparations containing the mixture and use of the mixture
WO2010146568A2 (en) * 2009-06-19 2010-12-23 Danisco A/S Bifidobacteria for treating diabetes and related conditions
US8962686B2 (en) 2010-04-28 2015-02-24 The Chinese University Of Hong Kong Method and medication for prevention and treatment of ocular hypertension and glaucoma
EP2389932A1 (en) 2010-05-28 2011-11-30 Lunamed AG Compositions for use in genetic disorders comprising 4-phenyl-butyric acid and its salts
MX2013001190A (es) 2010-07-29 2013-03-18 Cosmo Technologies Ltd Composiciones farmaceuticas y/o dieteticas con base en acidos grasos de cadena corta.
BR112012021624A2 (pt) * 2010-11-29 2017-02-07 Univ Putra Malaysia uso de cepas de bactérias de um ácido láctico para evitar ou tratar um tumor, composição para tratar ou previnir câncer, método para facilitar apoptose de células de câncer em um mamífero, kit para previnir ou tratar um câncer em um mamífero, e gêneros alimentícios para antitumor.
JP2014506923A (ja) * 2011-03-01 2014-03-20 クオラム イノベーションズ リミテッド ライアビリティ カンパニー 病原性バイオフィルムと関連した状態を治療するための物質および方法
WO2012131069A1 (en) 2011-03-31 2012-10-04 Proponent Biotech Gmbh Short chain fatty acids and their derivatives for use in treatment immunogenic disorders
KR20200106088A (ko) 2012-01-16 2020-09-10 엘라자베스 맥켄나 간 질환들 및 장애들의 치료를 위한 조성물들 및 방법들
GB201215289D0 (en) * 2012-08-28 2012-10-10 Medical Res Council Nanoparticle formulation
TWI463986B (zh) * 2012-08-29 2014-12-11 Univ China Medical 胚芽乳酸桿菌ｃｍｕ９９５菌株之新用途
WO2015006355A2 (en) 2013-07-09 2015-01-15 Puretech Ventures, Llc Compositions containing combinations of bioactive molecules derived from microbiota for treatment of disease
EP3033091B1 (en) * 2013-08-16 2022-09-07 Versitech Limited Probiotic composition and use thereof in the prevention and treatment of hepatocellular carcinoma

Also Published As

Publication number Publication date
US20180185307A1 (en) 2018-07-05
CN107405321A (zh) 2017-11-28
KR20170128247A (ko) 2017-11-22
US11963938B2 (en) 2024-04-23
JP2021020929A (ja) 2021-02-18
MX2017009532A (es) 2018-04-10
EP3247342A1 (en) 2017-11-29
US20180008565A1 (en) 2018-01-11
US20240342122A1 (en) 2024-10-17
IL253581A0 (en) 2017-09-28
WO2016118730A1 (en) 2016-07-28
AU2019201799A1 (en) 2019-04-04
SG10201907660YA (en) 2019-10-30
JP2018504457A (ja) 2018-02-15
US10231941B2 (en) 2019-03-19
CN115350171A (zh) 2022-11-18
AU2016209244A1 (en) 2017-08-17
EP3247342A4 (en) 2018-10-10
RU2017127597A3 (ja) 2019-07-17
JP6783247B2 (ja) 2020-11-11
US20190160031A1 (en) 2019-05-30
RU2017127597A (ru) 2019-02-25
AU2019201799B2 (en) 2020-10-15
ZA201704977B (en) 2022-12-21
US20220008369A1 (en) 2022-01-13
US10143669B2 (en) 2018-12-04
CA2974510A1 (en) 2016-07-28
AU2020239699A1 (en) 2020-10-15
JP2023027219A (ja) 2023-03-01

Similar Documents

Publication Publication Date Title
ZA201704977B (en) Use of short chain fatty acids in cancer prevention
HK1249524A1 (zh) 用於治療血載癌症的免疫檢查點抑制劑
IL258955A (en) Preparations and methods for the treatment of cancer
HK1256283A1 (zh) 治療癌症有用的二氫咪唑並吡嗪酮衍生物
ZA201607540B (en) Compositions and methods to treating hemoglobinopathies
HUE054673T2 (hu) Rák kezelésére szolgáló eljárások és készítmények
IL248767B (en) Trimethoxyphenyl-benzaimidazole compounds for cancer treatment
SG11201608217PA (en) Fatty acid composition and use thereof
SG11201803022TA (en) Compositions comprising fatty acids and their use
GB201420533D0 (en) Use of Nanomaterials in treating cancer
EP4043567C0 (en) METHOD AND COMPOSITIONS FOR TREATMENT OF CANCER
HK1250028A1 (zh) 2-苯基-6-咪唑基-吡啶-4-甲酰胺衍生物及其作為eaat3抑制劑的用途
GB201408297D0 (en) Treatment of cancer
SG10202001388YA (en) Use of ureidomustine (bo-1055) in cancer treatment
PL3233074T3 (pl) Leczenie niealkoholowych stłuszczeniowych chorób wątroby
SI3229790T1 (sl) Kompozicije, ki vsebujejo srednjeverižne trigliceride in ki se uporabljajo za zdravljenje epilepsije
GB201417456D0 (en) Treatment of cancer
GB201410695D0 (en) Uses of oligouronates in cancer treatment
ZA201403006B (en) Composition for use in treatment of cancer
GB201419559D0 (en) Therapeutic compositions and methods
GB201409362D0 (en) Treatment of cancer
GB201405449D0 (en) Treatment of cancer
GB201405075D0 (en) Treatment of cancer