SG11201704917XA - Radio-pharmaceutical complexes - Google Patents

Radio-pharmaceutical complexes

Info

Publication number
SG11201704917XA
SG11201704917XA SG11201704917XA SG11201704917XA SG11201704917XA SG 11201704917X A SG11201704917X A SG 11201704917XA SG 11201704917X A SG11201704917X A SG 11201704917XA SG 11201704917X A SG11201704917X A SG 11201704917XA SG 11201704917X A SG11201704917X A SG 11201704917XA
Authority
SG
Singapore
Prior art keywords
radio
pharmaceutical complexes
complexes
pharmaceutical
Prior art date
Application number
SG11201704917XA
Other languages
English (en)
Inventor
Alan Cuthbertson
Original Assignee
Bayer As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54884033&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201704917X(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer As filed Critical Bayer As
Publication of SG11201704917XA publication Critical patent/SG11201704917XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1021Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against cytokines, e.g. growth factors, VEGF, TNF, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • A61K51/103Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants against receptors for growth factors or receptors for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1051Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from breast, e.g. the antibody being herceptin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1069Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from blood cells, e.g. the cancer being a myeloma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1072Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from the reproductive system, e.g. ovaria, uterus, testes or prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG11201704917XA 2014-12-17 2015-12-15 Radio-pharmaceutical complexes SG11201704917XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201422512 2014-12-17
PCT/EP2015/079773 WO2016096843A1 (en) 2014-12-17 2015-12-15 Radio-pharmaceutical complexes

Publications (1)

Publication Number Publication Date
SG11201704917XA true SG11201704917XA (en) 2017-07-28

Family

ID=54884033

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201704917XA SG11201704917XA (en) 2014-12-17 2015-12-15 Radio-pharmaceutical complexes

Country Status (30)

Country Link
US (2) US20170340759A1 (he)
EP (1) EP3233137A1 (he)
JP (2) JP6821569B2 (he)
KR (1) KR20170094223A (he)
CN (1) CN107278155B (he)
AR (1) AR103063A1 (he)
AU (2) AU2015367722A1 (he)
BR (1) BR112017012841A2 (he)
CA (1) CA2970841A1 (he)
CL (1) CL2017001592A1 (he)
CO (1) CO2017005975A2 (he)
CR (1) CR20170256A (he)
CU (1) CU24493B1 (he)
DO (1) DOP2017000143A (he)
EA (1) EA201791350A9 (he)
EC (1) ECSP17038089A (he)
IL (1) IL252244B (he)
JO (1) JOP20150319B1 (he)
MA (1) MA41176A (he)
MX (1) MX2017008093A (he)
MY (1) MY194190A (he)
NI (1) NI201700076A (he)
PE (2) PE20230829A1 (he)
PH (1) PH12017501125A1 (he)
SG (1) SG11201704917XA (he)
TN (1) TN2017000255A1 (he)
TW (1) TWI654179B (he)
UA (1) UA125369C2 (he)
UY (1) UY36453A (he)
WO (1) WO2016096843A1 (he)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018011629A (es) * 2016-03-24 2019-03-14 Bayer Pharma AG Complejos radiofarmaceuticos.
BR112018075554A2 (pt) * 2016-06-10 2019-10-01 Bayer As complexos radiofarmacêuticos
EP3585436A1 (en) 2017-02-24 2020-01-01 Bayer AS Combination therapy comprising a radiopharmaceutical and a dna-repair inhibitor
US11554182B2 (en) 2017-03-30 2023-01-17 Cornell University Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer
US20210187134A1 (en) 2018-08-28 2021-06-24 Bayer As Combination of pi3k-inhibitors and targeted thorium conjugates
WO2020169537A1 (en) 2019-02-21 2020-08-27 Bayer Aktiengesellschaft Combination of pd-1/pd-l1 inhibitors and targeted thorium conjugates
EP3927339A1 (en) 2019-02-22 2021-12-29 Bayer Aktiengesellschaft Combination of ar antagonists and targeted thorium conjugates
CA3148382A1 (en) 2019-07-25 2021-01-28 Bayer As Targeted radiopharmaceuticals for the diagnosis and treatment of prostate cancer
TW202216771A (zh) 2020-06-26 2022-05-01 德商拜耳廠股份有限公司 用於治療應用之ccr8抗體
US20240108766A1 (en) 2021-01-22 2024-04-04 Bayer Aktiengesellschaft Lrrc15 antibodies and conjugates thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8158804B2 (en) * 2007-01-11 2012-04-17 Ge Healthcare As Chelating agents
GB201002508D0 (en) * 2010-02-12 2010-03-31 Algeta As Product
GB201208309D0 (en) * 2012-05-11 2012-06-27 Algeta As Complexes

Also Published As

Publication number Publication date
EP3233137A1 (en) 2017-10-25
TN2017000255A1 (en) 2018-10-19
TW201627286A (zh) 2016-08-01
PE20171181A1 (es) 2017-08-22
JP7160961B2 (ja) 2022-10-25
PH12017501125A1 (en) 2017-11-27
JOP20150319B1 (ar) 2021-08-17
AU2021202665A1 (en) 2021-05-27
US20170340759A1 (en) 2017-11-30
CU20170082A7 (es) 2017-10-05
JP2018506513A (ja) 2018-03-08
WO2016096843A1 (en) 2016-06-23
CU24493B1 (es) 2020-12-17
CR20170256A (es) 2017-08-11
JP2021063108A (ja) 2021-04-22
ECSP17038089A (es) 2017-07-31
CO2017005975A2 (es) 2017-11-30
MA41176A (fr) 2017-10-24
NI201700076A (es) 2017-09-22
CN107278155B (zh) 2021-03-30
IL252244A0 (he) 2017-07-31
AR103063A1 (es) 2017-04-12
CA2970841A1 (en) 2016-06-23
CN107278155A (zh) 2017-10-20
DOP2017000143A (es) 2017-07-15
KR20170094223A (ko) 2017-08-17
US20210322583A1 (en) 2021-10-21
AU2021202665B2 (en) 2023-04-27
BR112017012841A2 (pt) 2018-04-10
CL2017001592A1 (es) 2018-03-16
MY194190A (en) 2022-11-18
UA125369C2 (uk) 2022-03-02
IL252244B (he) 2020-10-29
EA201791350A1 (ru) 2017-12-29
UY36453A (es) 2016-07-29
MX2017008093A (es) 2018-02-09
JP6821569B2 (ja) 2021-01-27
PE20230829A1 (es) 2023-05-19
TWI654179B (zh) 2019-03-21
EA201791350A9 (ru) 2020-02-11
AU2015367722A1 (en) 2017-06-08

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