SG11201701857QA - Method for producing cerebellar progenitor tissue - Google Patents

Method for producing cerebellar progenitor tissue

Info

Publication number
SG11201701857QA
SG11201701857QA SG11201701857QA SG11201701857QA SG11201701857QA SG 11201701857Q A SG11201701857Q A SG 11201701857QA SG 11201701857Q A SG11201701857Q A SG 11201701857QA SG 11201701857Q A SG11201701857Q A SG 11201701857QA SG 11201701857Q A SG11201701857Q A SG 11201701857QA
Authority
SG
Singapore
Prior art keywords
producing
progenitor tissue
cerebellar progenitor
cerebellar
tissue
Prior art date
Application number
SG11201701857QA
Other languages
English (en)
Inventor
Yoshiki Sasai
Keiko MUGURUMA
Original Assignee
Riken
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riken, Sumitomo Chemical Co filed Critical Riken
Publication of SG11201701857QA publication Critical patent/SG11201701857QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0619Neurons
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • C12N2500/24Iron; Fe chelators; Transferrin
    • C12N2500/25Insulin-transferrin; Insulin-transferrin-selenium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/113Acidic fibroblast growth factor (aFGF, FGF-1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/119Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/15Transforming growth factor beta (TGF-β)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/19Growth and differentiation factors [GDF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/21Chemokines, e.g. MIP-1, MIP-2, RANTES, MCP, PF-4
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/33Insulin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes
    • C12N2501/72Transferases [EC 2.]
    • C12N2501/727Kinases (EC 2.7.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/03Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/08Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cells of the nervous system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/003D culture

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
SG11201701857QA 2014-09-08 2015-09-08 Method for producing cerebellar progenitor tissue SG11201701857QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014182758 2014-09-08
PCT/JP2015/075412 WO2016039317A1 (ja) 2014-09-08 2015-09-08 小脳前駆組織の製造方法

Publications (1)

Publication Number Publication Date
SG11201701857QA true SG11201701857QA (en) 2017-04-27

Family

ID=55459063

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201701857QA SG11201701857QA (en) 2014-09-08 2015-09-08 Method for producing cerebellar progenitor tissue

Country Status (13)

Country Link
US (1) US10781420B2 (ko)
EP (2) EP3192864A4 (ko)
JP (2) JP6680681B2 (ko)
KR (1) KR102604999B1 (ko)
CN (1) CN107109361A (ko)
AU (1) AU2015313264B2 (ko)
CA (1) CA2960465C (ko)
ES (1) ES2972541T3 (ko)
HK (1) HK1252956A1 (ko)
IL (1) IL251009B2 (ko)
MY (1) MY189592A (ko)
SG (1) SG11201701857QA (ko)
WO (1) WO2016039317A1 (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6680681B2 (ja) * 2014-09-08 2020-04-15 国立研究開発法人理化学研究所 小脳前駆組織の製造方法
AU2015336454B2 (en) 2014-10-24 2021-04-29 Riken Production method for retinal tissue
TWI810142B (zh) 2014-10-24 2023-08-01 日商住友製藥股份有限公司 神經組織的製造方法
KR102388863B1 (ko) 2016-04-22 2022-04-22 다이닛본 스미토모 세이야꾸 가부시끼가이샤 망막 조직의 제조 방법
KR102119148B1 (ko) * 2018-03-08 2020-06-04 고려대학교 산학협력단 신경조직 오가노이드의 제조방법, 이를 이용한 신경조직 형성 억제 물질의 스크리닝 방법 및 운동신경세포의 제조방법
KR102167257B1 (ko) * 2019-05-28 2020-10-19 부산대학교 산학협력단 토마티딘 처리를 통한 줄기세포의 성숙화된 심근세포로의 분화유도 촉진 방법
AU2020387259A1 (en) 2019-11-20 2022-06-09 Kyoto University Method for freezing neural cells
WO2021100830A1 (ja) 2019-11-20 2021-05-27 大日本住友製薬株式会社 細胞凝集体の凍結方法
CN113046306B (zh) * 2021-03-12 2022-10-18 广东东阳光药业有限公司 一种多能干细胞的培养方法
WO2023199952A1 (ja) * 2022-04-15 2023-10-19 株式会社幹細胞&デバイス研究所 薬剤の有効性の評価方法、神経細胞デバイス及びその製造方法、疾患モデル及びその作製方法、並びに成熟したプルキンエ細胞の作製方法
CN114958746B (zh) * 2022-06-08 2024-05-31 中国科学院动物研究所 一种多能干细胞诱导产生3d类脑体的方法及试剂盒
KR20240021432A (ko) * 2022-08-10 2024-02-19 주식회사 넥스트앤바이오 소뇌 오가노이드의 제조방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001508302A (ja) 1997-01-10 2001-06-26 ライフ テクノロジーズ,インコーポレイテッド 胚性幹細胞血清置換
KR100846643B1 (ko) * 2002-06-24 2008-07-16 미쓰비시 타나베 파마 코퍼레이션 신경 세포의 제조 방법
ZA200401646B (en) * 2003-03-12 2004-06-07 Reliance Life Sciences Pvt Ltd Derivation of terminally differentiated dopaminergic neurons from human embryonic stem cells.
CN1871340A (zh) * 2003-09-03 2006-11-29 利莱恩斯生命科学有限公司 从胚胎干细胞体外生产γ-氨基丁酸能神经元及其在神经障碍治疗中的应用
US8492147B2 (en) * 2004-06-18 2013-07-23 Riken Method of inducing the differentiation of embryonic stem cells into nerve by serum-free suspension culture
JP2008099662A (ja) 2006-09-22 2008-05-01 Institute Of Physical & Chemical Research 幹細胞の培養方法
JP2014023457A (ja) * 2012-07-25 2014-02-06 St Marianna Univ School Of Medicine 神経細胞シート及びその製造方法
JP6680681B2 (ja) * 2014-09-08 2020-04-15 国立研究開発法人理化学研究所 小脳前駆組織の製造方法

Also Published As

Publication number Publication date
KR102604999B1 (ko) 2023-11-23
HK1252956A1 (zh) 2019-06-06
EP3372673A1 (en) 2018-09-12
EP3372673B1 (en) 2023-12-13
AU2015313264A1 (en) 2017-04-27
US10781420B2 (en) 2020-09-22
CA2960465C (en) 2024-01-02
JP7107510B2 (ja) 2022-07-27
KR20170051497A (ko) 2017-05-11
JPWO2016039317A1 (ja) 2017-06-15
US20170253853A1 (en) 2017-09-07
WO2016039317A1 (ja) 2016-03-17
AU2015313264B2 (en) 2021-11-04
JP2020110176A (ja) 2020-07-27
EP3192864A1 (en) 2017-07-19
JP6680681B2 (ja) 2020-04-15
IL251009B2 (en) 2023-11-01
ES2972541T3 (es) 2024-06-13
IL251009A0 (en) 2017-04-30
CN107109361A (zh) 2017-08-29
MY189592A (en) 2022-02-18
IL251009B1 (en) 2023-07-01
EP3192864A4 (en) 2018-05-30
CA2960465A1 (en) 2016-03-17

Similar Documents

Publication Publication Date Title
HK1252956A1 (zh) 製備小腦祖先組織的方法
IL251856A0 (en) A method for producing retinal tissue
SG11201701945RA (en) Process for making cyclohexanone
SG11201701764WA (en) Process for making cyclohexanone
ZA201508687B (en) Process for producing composites
EP3333266C0 (en) SELENOEIN PRODUCTION PROCESS
SG11201701429SA (en) Process for making cyclohexanone
IL250258A0 (en) A method for preparing an adenohypophysis or its precursor tissue
PL3227023T3 (pl) Sposób wytwarzania kropel
EP3237195A4 (en) Methods for producing pressware
PT3196196T (pt) Método para a preparação de calcobutrol
EP3144337A4 (en) Method for producing polyamide
IL252173A0 (en) Methods for the production of methyl dichlorophosphane
HRP20181805T1 (hr) Postupak za proizvodnju poligvanidina
GB201414737D0 (en) Method for producing 3-hydroxypropanal
PT3237169T (pt) Processo para a produção de peças moldadas e produtos
SG11201701326YA (en) Method for producing oligosilane
HK1249098A1 (zh) 用於生產氟美他酚的方法
EP2931906A4 (en) PROCESS FOR PRODUCING FURFURAL
GB201503203D0 (en) Process for making esters
IL255093A0 (en) A method for the production of levoglucosenon
IL249283A0 (en) Process for the preparation of 3-chloro-2-vinylphenol
PL3299394T3 (pl) Sposób wytwarzania zmodyfikowanych ksylopolisacharydów
EP3242937A4 (en) Methods for producing abienol
HUE052742T2 (hu) Eljárás alkaltrészek gyártására