SG11201700133SA - Substance sealing method and target molecule detecting method - Google Patents
Substance sealing method and target molecule detecting methodInfo
- Publication number
- SG11201700133SA SG11201700133SA SG11201700133SA SG11201700133SA SG11201700133SA SG 11201700133S A SG11201700133S A SG 11201700133SA SG 11201700133S A SG11201700133S A SG 11201700133SA SG 11201700133S A SG11201700133S A SG 11201700133SA SG 11201700133S A SG11201700133S A SG 11201700133SA
- Authority
- SG
- Singapore
- Prior art keywords
- target molecule
- molecule detecting
- substance sealing
- detecting method
- sealing method
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- 238000007789 sealing Methods 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4044—Concentrating samples by chemical techniques; Digestion; Chemical decomposition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N37/00—Details not covered by any other group of this subclass
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Signal Processing (AREA)
- Dispersion Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014140700 | 2014-07-08 | ||
PCT/JP2015/003310 WO2016006208A1 (ja) | 2014-07-08 | 2015-07-01 | 物質封入方法及びターゲット分子を検出する方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201700133SA true SG11201700133SA (en) | 2017-03-30 |
Family
ID=55063860
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201700133SA SG11201700133SA (en) | 2014-07-08 | 2015-07-01 | Substance sealing method and target molecule detecting method |
SG10201811714UA SG10201811714UA (en) | 2014-07-08 | 2015-07-01 | Substance sealing method and target molecule detecting method |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201811714UA SG10201811714UA (en) | 2014-07-08 | 2015-07-01 | Substance sealing method and target molecule detecting method |
Country Status (12)
Country | Link |
---|---|
US (1) | US10451619B2 (pt) |
EP (1) | EP3168624B1 (pt) |
JP (1) | JP6611714B2 (pt) |
KR (1) | KR102437408B1 (pt) |
CN (1) | CN106662599B (pt) |
AU (1) | AU2015286488B2 (pt) |
BR (1) | BR112017000270B1 (pt) |
CA (1) | CA2953666C (pt) |
ES (1) | ES2831360T3 (pt) |
RU (1) | RU2691694C2 (pt) |
SG (2) | SG11201700133SA (pt) |
WO (1) | WO2016006208A1 (pt) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017043530A1 (ja) | 2015-09-08 | 2017-03-16 | 凸版印刷株式会社 | 生体物質検出方法 |
JP7016136B2 (ja) | 2016-09-05 | 2022-02-04 | 国立研究開発法人科学技術振興機構 | 病原性微生物検出のための方法及びキット |
WO2018043733A1 (ja) * | 2016-09-05 | 2018-03-08 | 国立研究開発法人科学技術振興機構 | 病原性微生物検出のための方法及びキット |
US10324041B2 (en) | 2016-12-21 | 2019-06-18 | Abbott Japan Co., Ltd. | Optical imaging system using lateral illumination for digital assays |
US11047854B2 (en) | 2017-02-06 | 2021-06-29 | Abbott Japan Llc | Methods for reducing noise in signal-generating digital assays |
JP7125763B2 (ja) * | 2017-03-29 | 2022-08-25 | 国立研究開発法人科学技術振興機構 | 微小物質封入方法及び微小物質検出方法並びに微小物質検出用デバイス |
JP7212940B2 (ja) * | 2017-03-29 | 2023-01-26 | 国立研究開発法人科学技術振興機構 | 微小物質検出方法及び微小物質検出用デバイス |
US11305282B2 (en) | 2017-03-29 | 2022-04-19 | Cornell University | Devices, processes, and systems for determination of nucleic acid sequence, expression, copy number, or methylation changes using combined nuclease, ligase, polymerase, and sequencing reactions |
US20200102587A1 (en) | 2017-04-05 | 2020-04-02 | Hitachi High-Technologies Corporation | Nucleic acid amplification method and nucleic acid analyzer |
US20200407769A1 (en) * | 2018-03-02 | 2020-12-31 | Japan Science And Technology Agency | Method for detecting enzymatic reaction product |
JP7219919B2 (ja) * | 2019-05-20 | 2023-02-09 | 日本航空電子工業株式会社 | 触媒反応生成物の電気化学的測定方法及びトランスデューサ |
JPWO2020235607A1 (pt) | 2019-05-21 | 2020-11-26 | ||
JP7201178B2 (ja) * | 2019-06-13 | 2023-01-10 | 日本航空電子工業株式会社 | 触媒反応生成物の電気化学的測定方法、電気化学測定装置及びトランスデューサ |
US20240168023A1 (en) | 2021-03-26 | 2024-05-23 | National Institute Of Advanced Industrial Science And Technology | Virus detection method using well array, well array, and detection device |
EP4296653A1 (en) | 2021-03-26 | 2023-12-27 | National Institute Of Advanced Industrial Science and Technology | Biological substance detection method using well array and particles, well array, and detection device |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7214540B2 (en) | 1999-04-06 | 2007-05-08 | Uab Research Foundation | Method for screening crystallization conditions in solution crystal growth |
EP1257805B1 (en) | 2000-02-10 | 2015-10-14 | Illumina, Inc. | Composition comprising a substrate with multiple assay locations for bead-based simultaneous processing of multiple samples, apparatus comprising the composition, and manufacturing method for the composition |
US7682565B2 (en) | 2002-12-20 | 2010-03-23 | Biotrove, Inc. | Assay apparatus and method using microfluidic arrays |
JP3727026B2 (ja) | 2003-04-10 | 2005-12-14 | 博行 野地 | 一分子酵素活性検出に用いられるマイクロチャンバと1000fL以下の液滴を調製する方法 |
EP2662135A3 (en) | 2003-08-27 | 2013-12-25 | President and Fellows of Harvard College | Method for mixing droplets in a microchannel |
JP4547301B2 (ja) * | 2005-05-13 | 2010-09-22 | 株式会社日立ハイテクノロジーズ | 液体搬送デバイス及び分析システム |
US8481125B2 (en) | 2005-05-21 | 2013-07-09 | Advanced Liquid Logic Inc. | Mitigation of biomolecular adsorption with hydrophilic polymer additives |
JP2007017253A (ja) * | 2005-07-07 | 2007-01-25 | Olympus Corp | 容器および粒子 |
ATE490971T1 (de) | 2006-04-18 | 2010-12-15 | Advanced Liquid Logic Inc | Biochemie auf tröpfchenbasis |
JP4866208B2 (ja) | 2006-10-31 | 2012-02-01 | 株式会社島津製作所 | マイクロ反応装置 |
WO2008116209A1 (en) | 2007-03-22 | 2008-09-25 | Advanced Liquid Logic, Inc. | Enzymatic assays for a droplet actuator |
JP5009125B2 (ja) | 2007-10-26 | 2012-08-22 | 日立マクセル株式会社 | 機能性粒子を利用したマイクロデバイスおよびそれを用いた処理方法 |
JP2009162549A (ja) | 2007-12-28 | 2009-07-23 | Nec Corp | 電気泳動チップ |
US20110065086A1 (en) | 2008-02-21 | 2011-03-17 | Otc Biotechnologies, Llc | Methods of producing homogeneous plastic-adherent aptamer-magnetic bead-fluorophore and other sandwich assays |
EP2257802A4 (en) | 2008-02-29 | 2014-07-02 | Univ Northwestern | BARRIERS TO FACILITATE BIOLOGICAL REACTIONS |
EP2315629B1 (en) | 2008-07-18 | 2021-12-15 | Bio-Rad Laboratories, Inc. | Droplet libraries |
JP5030897B2 (ja) * | 2008-08-28 | 2012-09-19 | メタウォーター株式会社 | 微生物計測方法 |
US10837883B2 (en) | 2009-12-23 | 2020-11-17 | Bio-Rad Laboratories, Inc. | Microfluidic systems and methods for reducing the exchange of molecules between droplets |
US8236574B2 (en) * | 2010-03-01 | 2012-08-07 | Quanterix Corporation | Ultra-sensitive detection of molecules or particles using beads or other capture objects |
US9110025B2 (en) | 2010-03-01 | 2015-08-18 | Quanterix Corporation | Methods and systems for extending dynamic range in assays for the detection of molecules or particles |
CN101947124B (zh) | 2010-06-25 | 2012-07-04 | 博奥生物有限公司 | 一种集成式微流控芯片装置及其使用方法 |
EP3447155A1 (en) * | 2010-09-30 | 2019-02-27 | Raindance Technologies, Inc. | Sandwich assays in droplets |
WO2012121310A1 (ja) * | 2011-03-08 | 2012-09-13 | 独立行政法人科学技術振興機構 | ビーズ封入方法、ターゲット分子を検出する方法、アレイ、キット及びターゲット分子検出装置 |
US9797837B2 (en) | 2012-08-31 | 2017-10-24 | The University Of Tokyo | Detector and detection method |
-
2015
- 2015-07-01 BR BR112017000270-1A patent/BR112017000270B1/pt active IP Right Grant
- 2015-07-01 WO PCT/JP2015/003310 patent/WO2016006208A1/ja active Application Filing
- 2015-07-01 KR KR1020167034481A patent/KR102437408B1/ko active IP Right Grant
- 2015-07-01 AU AU2015286488A patent/AU2015286488B2/en active Active
- 2015-07-01 CA CA2953666A patent/CA2953666C/en active Active
- 2015-07-01 CN CN201580036253.7A patent/CN106662599B/zh active Active
- 2015-07-01 US US15/321,312 patent/US10451619B2/en active Active
- 2015-07-01 EP EP15819235.1A patent/EP3168624B1/en active Active
- 2015-07-01 SG SG11201700133SA patent/SG11201700133SA/en unknown
- 2015-07-01 ES ES15819235T patent/ES2831360T3/es active Active
- 2015-07-01 SG SG10201811714UA patent/SG10201811714UA/en unknown
- 2015-07-01 JP JP2016532426A patent/JP6611714B2/ja active Active
- 2015-07-01 RU RU2017103947A patent/RU2691694C2/ru active
Also Published As
Publication number | Publication date |
---|---|
JPWO2016006208A1 (ja) | 2017-04-27 |
AU2015286488A1 (en) | 2017-02-16 |
US10451619B2 (en) | 2019-10-22 |
US20170176430A1 (en) | 2017-06-22 |
AU2015286488B2 (en) | 2020-07-16 |
JP6611714B2 (ja) | 2019-11-27 |
EP3168624B1 (en) | 2020-08-26 |
CN106662599A (zh) | 2017-05-10 |
RU2691694C2 (ru) | 2019-06-17 |
ES2831360T3 (es) | 2021-06-08 |
KR20170027716A (ko) | 2017-03-10 |
WO2016006208A1 (ja) | 2016-01-14 |
EP3168624A1 (en) | 2017-05-17 |
BR112017000270A2 (pt) | 2018-06-26 |
CA2953666C (en) | 2022-08-16 |
EP3168624A4 (en) | 2018-01-10 |
KR102437408B1 (ko) | 2022-08-29 |
SG10201811714UA (en) | 2019-01-30 |
CN106662599B (zh) | 2020-04-28 |
BR112017000270B1 (pt) | 2021-03-23 |
CA2953666A1 (en) | 2016-01-14 |
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