SG11201610878QA - Mutant hemagglutinin complex protein, and method for culturing pluripotent stem cells using same - Google Patents

Mutant hemagglutinin complex protein, and method for culturing pluripotent stem cells using same

Info

Publication number
SG11201610878QA
SG11201610878QA SG11201610878QA SG11201610878QA SG11201610878QA SG 11201610878Q A SG11201610878Q A SG 11201610878QA SG 11201610878Q A SG11201610878Q A SG 11201610878QA SG 11201610878Q A SG11201610878Q A SG 11201610878QA SG 11201610878Q A SG11201610878Q A SG 11201610878QA
Authority
SG
Singapore
Prior art keywords
stem cells
same
pluripotent stem
complex protein
culturing pluripotent
Prior art date
Application number
SG11201610878QA
Other languages
English (en)
Inventor
Masahiro Kinooka
Meehae Kim
Yukako Fujinaga
Yo Sugawara
Original Assignee
Univ Osaka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Osaka filed Critical Univ Osaka
Publication of SG11201610878QA publication Critical patent/SG11201610878QA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/72—Undefined extracts from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases (EC 2.)
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/14—Coculture with; Conditioned medium produced by hepatocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
SG11201610878QA 2014-06-27 2015-06-29 Mutant hemagglutinin complex protein, and method for culturing pluripotent stem cells using same SG11201610878QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014133364 2014-06-27
PCT/JP2015/068715 WO2015199243A1 (ja) 2014-06-27 2015-06-29 変異型ヘマグルチニン複合体タンパク質、及びそれを用いた多能性を有する幹細胞の培養方法

Publications (1)

Publication Number Publication Date
SG11201610878QA true SG11201610878QA (en) 2017-02-27

Family

ID=54938318

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201610878QA SG11201610878QA (en) 2014-06-27 2015-06-29 Mutant hemagglutinin complex protein, and method for culturing pluripotent stem cells using same

Country Status (10)

Country Link
US (1) US11230701B2 (ja)
EP (1) EP3162812A4 (ja)
JP (1) JP6355736B2 (ja)
KR (1) KR20170020431A (ja)
CN (1) CN106459223A (ja)
AU (1) AU2015281030A1 (ja)
BR (1) BR112016030510A2 (ja)
CA (1) CA2953670A1 (ja)
SG (1) SG11201610878QA (ja)
WO (1) WO2015199243A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107208064A (zh) * 2015-01-29 2017-09-26 国立大学法人东京大学 细胞的培养方法、细胞的凝集体、细胞凝集控制剂以及培养基
JP6949349B2 (ja) * 2016-12-20 2021-10-13 国立大学法人大阪大学 多能性幹細胞の増殖を促進するための組成物、及び多能性幹細胞の増殖促進方法
WO2019103111A1 (ja) 2017-11-24 2019-05-31 国立大学法人金沢大学 ヘマグルチニン複合体タンパク質及びその用途
WO2023149565A1 (ja) * 2022-02-07 2023-08-10 国立大学法人大阪大学 多能性幹細胞から網膜色素上皮細胞への分化誘導方法
WO2023149566A1 (ja) * 2022-02-07 2023-08-10 国立大学法人大阪大学 多能性幹細胞の分化誘導制御剤および分化誘導安定化剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7172764B2 (en) 2003-11-17 2007-02-06 Allergan, Inc. Rescue agents for treating botulinum toxin intoxications
JP2008169166A (ja) * 2007-01-14 2008-07-24 Tokyo Univ Of Agriculture & Technology 糖結合性ポリペプチド、複合材料、及び薬剤送達システム
CN102612562A (zh) * 2009-08-27 2012-07-25 色奈普提科研究有限公司 一种新的用于生成诱导性多能干(iPS)细胞或组织特异性细胞的蛋白质递送系统
JP2012143229A (ja) 2010-12-24 2012-08-02 Chiba Univ 多能性幹細胞培養用組成物およびその用途
CN103857797A (zh) * 2011-07-19 2014-06-11 帷幄生物技术公司 用于修复软骨损伤的非遗传修饰性重编程细胞的组合物和方法
TW201427687A (zh) * 2012-12-04 2014-07-16 Daiichi Sankyo Co Ltd 黏膜疫苗用佐劑
AU2013367082A1 (en) * 2012-12-28 2015-08-06 Osaka University Method for culturing pluripotent stem cells

Also Published As

Publication number Publication date
US20170130206A1 (en) 2017-05-11
AU2015281030A1 (en) 2017-02-16
US11230701B2 (en) 2022-01-25
EP3162812A4 (en) 2018-02-28
JPWO2015199243A1 (ja) 2017-04-27
EP3162812A1 (en) 2017-05-03
CN106459223A (zh) 2017-02-22
KR20170020431A (ko) 2017-02-22
BR112016030510A2 (pt) 2017-10-31
CA2953670A1 (en) 2015-12-30
WO2015199243A1 (ja) 2015-12-30
JP6355736B2 (ja) 2018-07-11

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