SG11201510201PA - Method for producing renal progenitor cells and drug comprising the same - Google Patents

Method for producing renal progenitor cells and drug comprising the same

Info

Publication number
SG11201510201PA
SG11201510201PA SG11201510201PA SG11201510201PA SG11201510201PA SG 11201510201P A SG11201510201P A SG 11201510201PA SG 11201510201P A SG11201510201P A SG 11201510201PA SG 11201510201P A SG11201510201P A SG 11201510201PA SG 11201510201P A SG11201510201P A SG 11201510201PA
Authority
SG
Singapore
Prior art keywords
drug
same
progenitor cells
renal progenitor
producing renal
Prior art date
Application number
SG11201510201PA
Other languages
English (en)
Inventor
Kenji Osafune
Takafumi Toyohara
Yukiko Yamagishi
Original Assignee
Univ Kyoto
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kyoto, Astellas Pharma Inc filed Critical Univ Kyoto
Publication of SG11201510201PA publication Critical patent/SG11201510201PA/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0684Cells of the urinary tract or kidneys
    • C12N5/0687Renal stem cells; Renal progenitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1841Transforming growth factor [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0684Cells of the urinary tract or kidneys
    • C12N5/0686Kidney cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/15Transforming growth factor beta (TGF-β)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/155Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999Small molecules not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG11201510201PA 2013-06-11 2014-06-11 Method for producing renal progenitor cells and drug comprising the same SG11201510201PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013123072 2013-06-11
JP2014092108 2014-04-25
PCT/JP2014/066081 WO2014200115A1 (ja) 2013-06-11 2014-06-11 腎前駆細胞の製造方法及び腎前駆細胞を含む医薬

Publications (1)

Publication Number Publication Date
SG11201510201PA true SG11201510201PA (en) 2016-01-28

Family

ID=52022399

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201510201PA SG11201510201PA (en) 2013-06-11 2014-06-11 Method for producing renal progenitor cells and drug comprising the same

Country Status (15)

Country Link
US (1) US11225642B2 (de)
EP (1) EP3020803B1 (de)
JP (1) JP6450311B2 (de)
KR (1) KR102145967B1 (de)
CN (1) CN105283542A (de)
AU (1) AU2014279065B2 (de)
BR (1) BR112015030918A2 (de)
CA (1) CA2915085C (de)
ES (1) ES2794074T3 (de)
IL (1) IL243023B (de)
MX (1) MX2015017036A (de)
RU (1) RU2696315C2 (de)
SG (1) SG11201510201PA (de)
TW (1) TWI629360B (de)
WO (1) WO2014200115A1 (de)

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KR101853477B1 (ko) * 2015-06-24 2018-04-30 전북대학교산학협력단 Sirt1 발현 조절을 통한 배아줄기세포로부터 신장전구세포로의 분화 조절 방법
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CN114457006B (zh) * 2022-02-21 2023-07-28 广州华越肾科再生医学科技有限公司 一种通过不连续分化制备肾脏足细胞的方法
CN114702591B (zh) * 2022-05-17 2022-09-23 诺赛联合(北京)生物医学科技有限公司 成体细胞衍生的类器官制备技术
CN117305222B (zh) * 2023-11-28 2024-02-20 广州华越肾科再生医学科技有限公司 多能干细胞分化为肾祖细胞的方法

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Also Published As

Publication number Publication date
MX2015017036A (es) 2016-07-21
CA2915085C (en) 2021-04-27
BR112015030918A2 (pt) 2017-12-05
RU2696315C2 (ru) 2019-08-01
EP3020803B1 (de) 2020-03-11
ES2794074T3 (es) 2020-11-17
WO2014200115A1 (ja) 2014-12-18
KR20160019509A (ko) 2016-02-19
AU2014279065A1 (en) 2016-01-21
CA2915085A1 (en) 2014-12-18
TWI629360B (zh) 2018-07-11
JPWO2014200115A1 (ja) 2017-02-23
US20160137985A1 (en) 2016-05-19
RU2015156492A (ru) 2017-07-14
US11225642B2 (en) 2022-01-18
EP3020803A4 (de) 2017-02-22
KR102145967B1 (ko) 2020-08-19
IL243023B (en) 2019-05-30
AU2014279065B2 (en) 2020-04-09
EP3020803A1 (de) 2016-05-18
RU2015156492A3 (de) 2018-04-02
TW201536917A (zh) 2015-10-01
CN105283542A (zh) 2016-01-27
JP6450311B2 (ja) 2019-01-09

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