SG11201508391SA - Tadalafil free base-containing film dosage form containing polyethylene glycol-based polymer and/or vinyl pyrrolidone-based polymer as dispersion stabilizer - Google Patents

Tadalafil free base-containing film dosage form containing polyethylene glycol-based polymer and/or vinyl pyrrolidone-based polymer as dispersion stabilizer

Info

Publication number
SG11201508391SA
SG11201508391SA SG11201508391SA SG11201508391SA SG11201508391SA SG 11201508391S A SG11201508391S A SG 11201508391SA SG 11201508391S A SG11201508391S A SG 11201508391SA SG 11201508391S A SG11201508391S A SG 11201508391SA SG 11201508391S A SG11201508391S A SG 11201508391SA
Authority
SG
Singapore
Prior art keywords
based polymer
polyethylene glycol
dosage form
free base
vinyl pyrrolidone
Prior art date
Application number
SG11201508391SA
Other languages
English (en)
Inventor
Hong Ryeol Jeon
Do-Woo Kwon
Bong-Sang Lee
Su-Jun Park
Bong-Geun Cha
Jun-Ki Kim
Jiyeong Han
Myeongcheol Kil
Original Assignee
Ctc Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51689788&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201508391S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ctc Bio Inc filed Critical Ctc Bio Inc
Publication of SG11201508391SA publication Critical patent/SG11201508391SA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
SG11201508391SA 2013-04-11 2014-04-11 Tadalafil free base-containing film dosage form containing polyethylene glycol-based polymer and/or vinyl pyrrolidone-based polymer as dispersion stabilizer SG11201508391SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20130040084 2013-04-11
PCT/KR2014/003160 WO2014168455A1 (ko) 2013-04-11 2014-04-11 분산안정화제로 폴리에틸렌글리콜계 고분자 및/또는 비닐피롤리돈계 고분자를 포함하는 타다라필 유리염기 함유 필름 제형

Publications (1)

Publication Number Publication Date
SG11201508391SA true SG11201508391SA (en) 2015-11-27

Family

ID=51689788

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201508391SA SG11201508391SA (en) 2013-04-11 2014-04-11 Tadalafil free base-containing film dosage form containing polyethylene glycol-based polymer and/or vinyl pyrrolidone-based polymer as dispersion stabilizer

Country Status (15)

Country Link
US (2) US20160074396A1 (ko)
EP (1) EP2985020B1 (ko)
JP (1) JP6470257B2 (ko)
KR (1) KR102223105B1 (ko)
CN (1) CN105209025B (ko)
AP (1) AP2015008840A0 (ko)
AU (1) AU2014251532B2 (ko)
BR (1) BR112015025859A2 (ko)
CL (1) CL2015003004A1 (ko)
EA (1) EA033893B1 (ko)
MX (1) MX2015013840A (ko)
MY (1) MY173159A (ko)
SG (1) SG11201508391SA (ko)
WO (1) WO2014168455A1 (ko)
ZA (1) ZA201508272B (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101538985B1 (ko) * 2014-09-02 2015-07-24 주식회사 서울제약 타다라필 구강붕해필름 및 이의 제조방법
KR101634382B1 (ko) 2015-10-20 2016-06-28 미래제약 주식회사 타다라필 경구용 액제
CN106176685A (zh) * 2016-07-29 2016-12-07 齐鲁制药有限公司 一种包含他达拉非的口溶膜剂及其制备方法
CZ2017781A3 (cs) * 2017-12-05 2019-06-12 Zentiva, K.S. Těžko rozpustné terapeutická činidla,která patřící do BCS skupiny II nebo IV, suspendovaná v kapalné formulaci a/nebo v konečné nanovláknité struktuře
EP3749370A1 (de) * 2018-02-07 2020-12-16 Smawa GmbH Pharmazeutische formulierungen, verfahren zum herstellen einer pharmazeutischen formulierung sowie ein arzneimittel umfassend eine solche
US10828254B2 (en) 2018-09-28 2020-11-10 Intelgenx Corp. Oral film formulation for modulating absorption profile
KR102110179B1 (ko) 2019-07-18 2020-05-13 주식회사 서울제약 타다라필 또는 그의 약제학적으로 허용되는 염 함유 구강붕해필름

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1200090B1 (en) 1999-08-03 2013-09-11 ICOS Corporation Pharmaceutical formulation comprising a beta-carboline and its use for treating sexual dysfunction
US6821975B1 (en) 1999-08-03 2004-11-23 Lilly Icos Llc Beta-carboline drug products
CA2473967C (en) * 2001-10-12 2011-06-14 Monosolrx Llc Thin film with non-self-aggregating uniform heterogeneity, process for their production and drug delivery systems made therefrom
PE20060935A1 (es) * 2004-10-21 2006-10-26 Novartis Ag Composicion farmaceutica que comprende diclofenaco
KR100627687B1 (ko) * 2005-04-20 2006-09-25 주식회사 씨티씨바이오 시부트라민 유리염기 함유 조성물 및 이의 제조방법
CA2622200A1 (en) * 2005-09-13 2007-03-22 Elan Pharma International, Limited Nanoparticulate tadalafil formulations
GB0607105D0 (en) * 2006-04-10 2006-05-17 Leuven K U Res & Dev Enhancing solubility and dissolution rate of poorly soluble drugs
IL175338A0 (en) * 2006-05-01 2006-09-05 Biota Ltd Orally administrable films and preparation thereof
KR100855566B1 (ko) * 2006-09-12 2008-09-03 (주) 아모젠 경구용 소모성 필름
DE102007028869A1 (de) * 2007-06-22 2008-12-24 Ratiopharm Gmbh Verfahren zur Herstellung eines Arzneimittels enthaltend Tadalafil
US20090047330A1 (en) * 2007-08-17 2009-02-19 Ramesh Bangalore Oral fast dissolving films for erectile dysfunction bioactive agents
MX2011001405A (es) * 2008-08-06 2011-03-21 Pfizer Ltd Compuestos de diazepina y diazocano como agonistas de mc4.
KR101074271B1 (ko) * 2009-06-25 2011-10-17 (주)차바이오앤디오스텍 불쾌한 맛을 효과적으로 은폐한 경구용 속용 필름
KR20110041412A (ko) * 2009-10-15 2011-04-21 (주)씨엘팜 Ｐｄｅ5 억제제를 함유하는 구강 용해성 필름
US20110136815A1 (en) * 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US20110263606A1 (en) * 2010-04-26 2011-10-27 Horst Zerbe Solid oral dosage forms comprising tadalafil
WO2012053006A2 (en) * 2010-10-18 2012-04-26 Panacea Biotec Ltd Improved oral fast dissolving films comprising combination of polymers and method of preparation thereof
EA027720B1 (ru) * 2011-02-11 2017-08-31 СиТиСи БАЙО, ИНК. Способ получения пленки, содержащей свободное основание силденафила
KR101303479B1 (ko) * 2011-07-28 2013-09-06 (주)씨엘팜 가식성 필름형성 조성물 및 약물이 함유된 가식성 필름형 제제
US20150202168A1 (en) * 2012-08-17 2015-07-23 Sanovel llac Sanayi Ve Ticaret Anonim Sirketi Oral film formulations comprising dapoxetine and tadalafil
CN102824333B (zh) * 2012-09-26 2014-05-14 苏州大学 一种口腔速溶膜剂及其制备方法

Also Published As

Publication number Publication date
ZA201508272B (en) 2018-05-30
WO2014168455A1 (ko) 2014-10-16
CL2015003004A1 (es) 2016-05-13
CN105209025A (zh) 2015-12-30
BR112015025859A2 (pt) 2017-07-25
AU2014251532B2 (en) 2019-05-23
JP2016516784A (ja) 2016-06-09
CN105209025B (zh) 2019-06-18
AU2014251532A1 (en) 2015-11-12
KR102223105B1 (ko) 2021-03-04
MY173159A (en) 2019-12-31
US20200085818A1 (en) 2020-03-19
EA201591950A1 (ru) 2016-04-29
US20160074396A1 (en) 2016-03-17
KR20140123027A (ko) 2014-10-21
MX2015013840A (es) 2016-06-02
EA033893B1 (ru) 2019-12-06
JP6470257B2 (ja) 2019-02-13
EP2985020A1 (en) 2016-02-17
EP2985020B1 (en) 2021-06-23
EP2985020A4 (en) 2016-10-12
AP2015008840A0 (en) 2015-11-30

Similar Documents

Publication Publication Date Title
ZA201508272B (en) Tadalafil free base-containing film dosage form containing polyethylene glycol-based polymer and/or vinyl pyrrolidone-based polymer as dispersion stabilizer
EP3228648A4 (en) Copolycarbonate and composition containing same
EP3037479A4 (en) Halogen-free resin composition and use thereof
EP3046956A4 (en) Polymer films
EP3156227A4 (en) Transparent article with antifog film
EP3053963A4 (en) Halogen-free resin composition and use thereof
EP2970605A4 (en) PROCESS FOR THE RETICULATION OF POLYMERIC COMPOSITIONS IN THE PRESENCE OF ATMOSPHERIC OXYGEN
PL3313918T3 (pl) Wysoko-przezroczyste powlekane folie z trioctanu celulozy
PL3129695T3 (pl) Polimerowa folia wielowarstwowa
EP3048127A4 (en) Copolycarbonate and composition containing same
EP3162830A4 (en) Monomer composition and curable composition containing same
EP3246351A4 (en) Triazine-ring-containing polymer and composition containing same
EP3162822A4 (en) Monomer composition and curable composition containing same
EP2985324A4 (en) FOIL WITH COPOLYMER OR COMPOSITION
EP3181612A4 (en) Polymer containing triazine ring and composition containing same
EP3208286A4 (en) Vinyl alcohol polymer and use thereof
EP3067379A4 (en) Copolycarbonate and composition containing same
HK1221433A1 (zh) 納米結構膜的基於盒體的分配
EP3234054A4 (en) Surface protection film
EP3023472A4 (en) Composition containing hfc and hfo
EP3031863A4 (en) Halogen-free resin composition and uses thereof
EP3205693A4 (en) Resin composition and film
EP3297440A4 (en) COMPOSITION WITH CARBOPLATIN AND USE
EP3194458A4 (en) Vinyl acetate binders in above-critical pigment volume concentration coatings composition
EP3214137A4 (en) Particles for resin modification and vinyl chloride resin composition containing same