SG11201505370RA - Dynamic suspension drying (dsd) to control ostwald ripening - Google Patents
Dynamic suspension drying (dsd) to control ostwald ripeningInfo
- Publication number
- SG11201505370RA SG11201505370RA SG11201505370RA SG11201505370RA SG11201505370RA SG 11201505370R A SG11201505370R A SG 11201505370RA SG 11201505370R A SG11201505370R A SG 11201505370RA SG 11201505370R A SG11201505370R A SG 11201505370RA SG 11201505370R A SG11201505370R A SG 11201505370RA
- Authority
- SG
- Singapore
- Prior art keywords
- dsd
- ostwald ripening
- dynamic suspension
- suspension drying
- control
- Prior art date
Links
- 238000001016 Ostwald ripening Methods 0.000 title 1
- 238000001035 drying Methods 0.000 title 1
- 239000000725 suspension Substances 0.000 title 1
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B3/00—Drying solid materials or objects by processes involving the application of heat
- F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
- F26B3/10—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B1/00—Preliminary treatment of solid materials or objects to facilitate drying, e.g. mixing or backmixing the materials to be dried with predominantly dry solids
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B3/00—Drying solid materials or objects by processes involving the application of heat
- F26B3/02—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air
- F26B3/10—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it
- F26B3/12—Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour carrying the materials or objects to be dried with it in the form of a spray, i.e. sprayed or dispersed emulsions or suspensions
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT106738A PT106738B (pt) | 2013-01-09 | 2013-01-09 | Método para o controlo do fenómeno de degradação difusional de ostwald (ostwald ripening) no processamento de partículas de um ingrediente farmacêutico |
| PCT/GB2014/050055 WO2014108687A1 (en) | 2013-01-09 | 2014-01-09 | Dynamic suspension drying (dsd) to control ostwald ripening |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201505370RA true SG11201505370RA (en) | 2015-08-28 |
Family
ID=49999991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201505370RA SG11201505370RA (en) | 2013-01-09 | 2014-01-09 | Dynamic suspension drying (dsd) to control ostwald ripening |
Country Status (13)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT108368B (pt) | 2015-03-31 | 2018-11-05 | Hovione Farm S A | Produção contínua de partículas |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4826689A (en) | 1984-05-21 | 1989-05-02 | University Of Rochester | Method for making uniformly sized particles from water-insoluble organic compounds |
| US5665383A (en) * | 1993-02-22 | 1997-09-09 | Vivorx Pharmaceuticals, Inc. | Methods for the preparation of immunostimulating agents for in vivo delivery |
| US6749868B1 (en) * | 1993-02-22 | 2004-06-15 | American Bioscience, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
| US5439686A (en) * | 1993-02-22 | 1995-08-08 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor |
| US6096331A (en) * | 1993-02-22 | 2000-08-01 | Vivorx Pharmaceuticals, Inc. | Methods and compositions useful for administration of chemotherapeutic agents |
| US5997904A (en) * | 1993-02-22 | 1999-12-07 | American Bioscience, Inc. | Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof |
| US5916596A (en) * | 1993-02-22 | 1999-06-29 | Vivorx Pharmaceuticals, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
| NZ262679A (en) * | 1993-02-22 | 1997-08-22 | Vivorx Pharmaceuticals Inc | Compositions for in vivo delivery of pharmaceutical agents where the agents are contained in a polymeric shell |
| US5665382A (en) * | 1993-02-22 | 1997-09-09 | Vivorx Pharmaceuticals, Inc. | Methods for the preparation of pharmaceutically active agents for in vivo delivery |
| US5650156A (en) * | 1993-02-22 | 1997-07-22 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of nutriceuticals and compositions useful therefor |
| CA2371912C (en) * | 1999-05-21 | 2010-02-16 | American Bioscience, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
| US6318649B1 (en) * | 1999-10-06 | 2001-11-20 | Cornerstone Technologies, Llc | Method of creating ultra-fine particles of materials using a high-pressure mill |
| JP5102423B2 (ja) * | 2000-04-20 | 2012-12-19 | オバン・エナジー・リミテッド | 改善された水不溶性薬剤粒子の処理 |
| WO2002004125A2 (en) * | 2000-07-06 | 2002-01-17 | Cornerstone Technologies, L.L.C. | Multi-stage size reduction, blending and drying system and method |
| AU2002317409B2 (en) * | 2001-08-06 | 2007-06-21 | Astrazeneca Ab | Aqueous dispersion comprising stable nanoparticles of a water-insoluble active and an excipient like middle chain triglycerides (MCT) |
| WO2004052567A2 (en) * | 2002-12-06 | 2004-06-24 | Cornerstone Technologies, L.L.C. | High g mill in a blending and drying system |
| JP5571380B2 (ja) * | 2006-07-24 | 2014-08-13 | ルミナス バイオサイエンシズ，インコーポレイテッド | オストワルド熟成を減少させた水不溶性の医薬品物質の固体ナノ粒子処方物 |
| PT105058B (pt) * | 2010-04-21 | 2013-04-17 | Hovione Farmaciencia S A | Processo para processamento de partículas de ingredientes activos farmacêuticos |
-
2013
- 2013-01-09 PT PT106738A patent/PT106738B/pt active IP Right Grant
-
2014
- 2014-01-09 JP JP2015552139A patent/JP6316847B2/ja not_active Expired - Fee Related
- 2014-01-09 CN CN201480011112.5A patent/CN105007900B/zh not_active Expired - Fee Related
- 2014-01-09 WO PCT/GB2014/050055 patent/WO2014108687A1/en not_active Ceased
- 2014-01-09 CA CA2897277A patent/CA2897277C/en active Active
- 2014-01-09 HU HUE14701124A patent/HUE036691T2/hu unknown
- 2014-01-09 EP EP14701124.1A patent/EP2874609B1/en active Active
- 2014-01-09 SG SG11201505370RA patent/SG11201505370RA/en unknown
- 2014-01-09 US US14/760,095 patent/US10151529B2/en active Active
- 2014-01-09 DK DK14701124.1T patent/DK2874609T3/en active
- 2014-01-09 BR BR112015016605-9A patent/BR112015016605B1/pt not_active IP Right Cessation
- 2014-01-09 ES ES14701124.1T patent/ES2659968T3/es active Active
-
2015
- 2015-07-08 IL IL239845A patent/IL239845B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| US10151529B2 (en) | 2018-12-11 |
| PT106738A (pt) | 2014-07-09 |
| CA2897277C (en) | 2020-09-01 |
| JP6316847B2 (ja) | 2018-04-25 |
| HUE036691T2 (hu) | 2018-07-30 |
| JP2016508989A (ja) | 2016-03-24 |
| EP2874609A1 (en) | 2015-05-27 |
| WO2014108687A1 (en) | 2014-07-17 |
| IL239845A0 (en) | 2015-08-31 |
| CN105007900A (zh) | 2015-10-28 |
| IL239845B (en) | 2019-05-30 |
| ES2659968T3 (es) | 2018-03-20 |
| EP2874609B1 (en) | 2017-12-27 |
| BR112015016605B1 (pt) | 2022-11-29 |
| CA2897277A1 (en) | 2014-07-17 |
| DK2874609T3 (en) | 2018-04-09 |
| PT106738B (pt) | 2015-06-08 |
| US20150354891A1 (en) | 2015-12-10 |
| BR112015016605A2 (pt) | 2017-07-11 |
| CN105007900B (zh) | 2019-04-12 |
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