SG11201504883PA - Peptides as oxytocin agonists - Google Patents

Peptides as oxytocin agonists

Info

Publication number
SG11201504883PA
SG11201504883PA SG11201504883PA SG11201504883PA SG11201504883PA SG 11201504883P A SG11201504883P A SG 11201504883PA SG 11201504883P A SG11201504883P A SG 11201504883PA SG 11201504883P A SG11201504883P A SG 11201504883PA SG 11201504883P A SG11201504883P A SG 11201504883PA
Authority
SG
Singapore
Prior art keywords
peptides
oxytocin agonists
oxytocin
agonists
Prior art date
Application number
SG11201504883PA
Other languages
English (en)
Inventor
Caterina Bissantz
Konrad Bleicher
Christophe Grundschober
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SG11201504883PA publication Critical patent/SG11201504883PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/16Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychiatry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201504883PA 2012-12-21 2013-12-17 Peptides as oxytocin agonists SG11201504883PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12199012 2012-12-21
PCT/EP2013/076783 WO2014095773A1 (fr) 2012-12-21 2013-12-17 Peptides en tant qu'agonistes de l'oxytocine

Publications (1)

Publication Number Publication Date
SG11201504883PA true SG11201504883PA (en) 2015-07-30

Family

ID=47471593

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201504883PA SG11201504883PA (en) 2012-12-21 2013-12-17 Peptides as oxytocin agonists

Country Status (34)

Country Link
US (1) US9868766B2 (fr)
EP (1) EP2935312B1 (fr)
JP (1) JP6067878B2 (fr)
KR (1) KR101819804B1 (fr)
CN (1) CN104870466B (fr)
AR (1) AR094225A1 (fr)
AU (1) AU2013363768B2 (fr)
BR (1) BR112015014010A2 (fr)
CA (1) CA2895150C (fr)
CL (1) CL2015001724A1 (fr)
CR (1) CR20150271A (fr)
DK (1) DK2935312T3 (fr)
EA (1) EA026687B1 (fr)
ES (1) ES2690317T3 (fr)
HK (1) HK1208477A1 (fr)
HR (1) HRP20181569T1 (fr)
HU (1) HUE039848T2 (fr)
IL (1) IL239519A (fr)
LT (1) LT2935312T (fr)
MA (1) MA38272A1 (fr)
MX (1) MX358684B (fr)
MY (1) MY176398A (fr)
NZ (1) NZ708175A (fr)
PE (1) PE20151446A1 (fr)
PH (1) PH12015501145B1 (fr)
PL (1) PL2935312T3 (fr)
PT (1) PT2935312T (fr)
RS (1) RS57690B1 (fr)
SG (1) SG11201504883PA (fr)
SI (1) SI2935312T1 (fr)
TW (1) TWI558726B (fr)
UA (1) UA119034C2 (fr)
WO (1) WO2014095773A1 (fr)
ZA (1) ZA201504186B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10039777B2 (en) 2012-03-20 2018-08-07 Neuro-Lm Sas Methods and pharmaceutical compositions of the treatment of autistic syndrome disorders
CA2894542C (fr) 2012-12-21 2023-10-31 Alios Biopharma, Inc. Nucleosides, nucleotides substitues et leurs analogues
RS57690B1 (sr) 2012-12-21 2018-11-30 Hoffmann La Roche Peptidi kao agonisti oksitocina
UA111305C2 (uk) 2012-12-21 2016-04-11 Пфайзер Інк. Конденсовані лактами арилу та гетероарилу
KR102116107B1 (ko) 2013-12-30 2020-05-28 삼성디스플레이 주식회사 표시 장치
WO2015106200A2 (fr) 2014-01-10 2015-07-16 Cornell University Dipeptides utilisés en tant qu'inhibiteurs des immunoprotéasomes humains
CA2949173A1 (fr) 2014-06-03 2015-12-10 Caterina Bissantz Peptides utilises en tant qu'agonistes d'oxytocine
PE20161552A1 (es) 2014-06-17 2017-01-11 Pfizer Compuestos de dihidroisoquinolinona sustituida
US10588980B2 (en) 2014-06-23 2020-03-17 Novartis Ag Fatty acids and their use in conjugation to biomolecules
MY178266A (en) * 2014-08-07 2020-10-07 Hoffmann La Roche Processes for the preparation of oxytocin analogues
CN114796207A (zh) * 2014-08-18 2022-07-29 康奈尔大学 作为人免疫蛋白酶体的抑制剂的二肽模拟物
US10441627B2 (en) * 2014-09-19 2019-10-15 Ferring B.V. Method of treating prader-willi syndrome
KR20180064427A (ko) 2015-10-15 2018-06-14 코넬 유니버시티 프로테아좀 억제제 및 이의 용도
EP3694605A4 (fr) 2017-10-11 2021-10-27 Cornell University Inhibiteurs peptidomimétiques du protéasome
WO2020061416A1 (fr) 2018-09-20 2020-03-26 Levo Therapeutics, Inc. Produit médicamenteux à la carbétocine et son procédé de préparation
WO2020061414A1 (fr) 2018-09-20 2020-03-26 Levo Therapeutics, Inc. Formulations intranasales stables de carbétocine
WO2021126990A1 (fr) * 2019-12-16 2021-06-24 The Scripps Research Institute Dérivés d'ocytocine ayant des propriétés améliorées

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0910345B1 (pt) 2008-03-31 2021-08-17 Ferring B.V. Compostos análogos de oxitocina, composição farmacêutica compreendendo os mesmos e uso dos ditos análogos
TWI463990B (zh) * 2009-09-21 2014-12-11 Ferring Bv 催產素受體促進劑
ES2509270T3 (es) * 2009-10-01 2014-10-17 The University Of Sydney Terapia y prevención del alcoholismo
RS57690B1 (sr) 2012-12-21 2018-11-30 Hoffmann La Roche Peptidi kao agonisti oksitocina

Also Published As

Publication number Publication date
CR20150271A (es) 2015-08-28
CA2895150A1 (fr) 2014-06-26
PE20151446A1 (es) 2015-09-28
MA38272A1 (fr) 2017-07-31
WO2014095773A1 (fr) 2014-06-26
RS57690B1 (sr) 2018-11-30
AU2013363768B2 (en) 2016-02-04
PH12015501145A1 (en) 2015-08-10
UA119034C2 (uk) 2019-04-25
AR094225A1 (es) 2015-07-22
PH12015501145B1 (en) 2015-08-10
KR101819804B1 (ko) 2018-01-17
US20150284434A1 (en) 2015-10-08
CN104870466B (zh) 2018-05-18
ES2690317T3 (es) 2018-11-20
DK2935312T3 (en) 2018-10-22
EA026687B1 (ru) 2017-05-31
HRP20181569T1 (hr) 2018-11-30
KR20150085845A (ko) 2015-07-24
MX2015007365A (es) 2015-10-14
MX358684B (es) 2018-08-31
BR112015014010A2 (pt) 2017-07-11
CN104870466A (zh) 2015-08-26
TWI558726B (zh) 2016-11-21
SI2935312T1 (sl) 2018-11-30
IL239519A (en) 2017-06-29
EP2935312B1 (fr) 2018-08-08
CL2015001724A1 (es) 2015-10-16
NZ708175A (en) 2020-06-26
JP6067878B2 (ja) 2017-01-25
TW201429994A (zh) 2014-08-01
MY176398A (en) 2020-08-05
JP2016503044A (ja) 2016-02-01
AU2013363768A1 (en) 2015-06-04
HK1208477A1 (en) 2016-03-04
EP2935312A1 (fr) 2015-10-28
LT2935312T (lt) 2018-10-25
PT2935312T (pt) 2018-10-26
CA2895150C (fr) 2019-11-26
HUE039848T2 (hu) 2019-02-28
IL239519A0 (en) 2015-08-31
US9868766B2 (en) 2018-01-16
EA201591078A1 (ru) 2015-10-30
PL2935312T3 (pl) 2018-12-31
ZA201504186B (en) 2016-04-28

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