SG11201503274WA - N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfoximine group - Google Patents

N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfoximine group

Info

Publication number
SG11201503274WA
SG11201503274WA SG11201503274WA SG11201503274WA SG11201503274WA SG 11201503274W A SG11201503274W A SG 11201503274WA SG 11201503274W A SG11201503274W A SG 11201503274WA SG 11201503274W A SG11201503274W A SG 11201503274WA SG 11201503274W A SG11201503274W A SG 11201503274WA
Authority
SG
Singapore
Prior art keywords
pyrimidin
pyridin
amine derivatives
derivatives containing
sulfoximine group
Prior art date
Application number
SG11201503274WA
Other languages
English (en)
Inventor
Ulrich Lücking
Niels Böhnke
Arne Scholz
Philip Lienau
Gerhard Siemeister
Ulf Bömer
Dirk Kosemund
Rolf Bohlmann
Ludwig Zorn
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of SG11201503274WA publication Critical patent/SG11201503274WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Saccharide Compounds (AREA)
SG11201503274WA 2012-11-15 2013-11-13 N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfoximine group SG11201503274WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12192855 2012-11-15
PCT/EP2013/073683 WO2014076111A1 (en) 2012-11-15 2013-11-13 N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfoximine group

Publications (1)

Publication Number Publication Date
SG11201503274WA true SG11201503274WA (en) 2015-06-29

Family

ID=47148673

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201503274WA SG11201503274WA (en) 2012-11-15 2013-11-13 N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfoximine group

Country Status (27)

Country Link
US (1) US9650361B2 (es)
EP (1) EP2920164B1 (es)
JP (1) JP6263194B2 (es)
KR (1) KR20150082604A (es)
CN (1) CN104918932B (es)
AP (1) AP2015008436A0 (es)
AR (1) AR093503A1 (es)
AU (1) AU2013346866A1 (es)
BR (1) BR112015010484A2 (es)
CA (1) CA2891361C (es)
CL (1) CL2015001319A1 (es)
CR (1) CR20150257A (es)
CU (1) CU20150051A7 (es)
DO (1) DOP2015000117A (es)
EA (1) EA201590892A1 (es)
ES (1) ES2622566T3 (es)
HK (1) HK1215027A1 (es)
IL (1) IL238370A0 (es)
MA (1) MA38091B1 (es)
MX (1) MX2015006171A (es)
PE (1) PE20151142A1 (es)
PH (1) PH12015501076A1 (es)
SG (1) SG11201503274WA (es)
TN (1) TN2015000186A1 (es)
TW (1) TW201418243A (es)
UY (1) UY35138A (es)
WO (1) WO2014076111A1 (es)

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TWI555737B (zh) 2011-05-24 2016-11-01 拜耳知識產權公司 含有硫醯亞胺基團之4-芳基-n-苯基-1,3,5-三氮雜苯-2-胺
CN105283453B (zh) * 2012-10-18 2018-06-22 拜耳药业股份公司 含砜基的n-(吡啶-2-基)嘧啶-4-胺衍生物
WO2016059011A1 (en) 2014-10-16 2016-04-21 Bayer Pharma Aktiengesellschaft Fluorinated benzofuranyl-pyrimidine derivatives containing a sulfone group
CN107001341B (zh) * 2014-10-16 2020-08-07 拜耳医药股份有限公司 含有磺亚胺基的氟化苯并呋喃基-嘧啶衍生物
EP3356373B1 (en) 2015-09-29 2020-02-19 Bayer Pharma Aktiengesellschaft Novel macrocyclic sulfondiimine compounds
WO2017060167A1 (en) 2015-10-08 2017-04-13 Bayer Pharma Aktiengesellschaft Novel modified macrocyclic compounds
WO2017060322A2 (en) 2015-10-10 2017-04-13 Bayer Pharma Aktiengesellschaft Ptefb-inhibitor-adc
PL3601253T3 (pl) 2017-03-28 2022-01-17 Bayer Aktiengesellschaft Nowe hamujące ptefb związki makrocykliczne
WO2018177889A1 (en) 2017-03-28 2018-10-04 Bayer Aktiengesellschaft Novel ptefb inhibiting macrocyclic compounds
KR20200071756A (ko) * 2017-10-17 2020-06-19 메르크 파텐트 게엠베하 피리미딘 TBK/IKKε 억제제 화합물 및 이의 용도

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Also Published As

Publication number Publication date
HK1215027A1 (zh) 2016-08-12
BR112015010484A2 (pt) 2017-07-11
US20150291559A1 (en) 2015-10-15
UY35138A (es) 2014-06-30
JP6263194B2 (ja) 2018-01-17
DOP2015000117A (es) 2015-06-15
JP2016501194A (ja) 2016-01-18
WO2014076111A1 (en) 2014-05-22
CN104918932B (zh) 2017-07-18
KR20150082604A (ko) 2015-07-15
PE20151142A1 (es) 2015-08-23
ES2622566T3 (es) 2017-07-06
EP2920164B1 (en) 2017-02-01
CA2891361A1 (en) 2014-05-22
MX2015006171A (es) 2015-08-10
CL2015001319A1 (es) 2015-07-17
CA2891361C (en) 2021-07-20
CU20150051A7 (es) 2015-11-27
TW201418243A (zh) 2014-05-16
EP2920164A1 (en) 2015-09-23
TN2015000186A1 (en) 2016-10-03
AR093503A1 (es) 2015-06-10
US9650361B2 (en) 2017-05-16
AU2013346866A1 (en) 2015-05-21
CN104918932A (zh) 2015-09-16
CR20150257A (es) 2015-07-01
MA38091A2 (fr) 2016-10-31
MA38091A3 (fr) 2017-03-31
PH12015501076A1 (en) 2015-08-03
EA201590892A1 (ru) 2015-11-30
IL238370A0 (en) 2015-06-30
AP2015008436A0 (en) 2015-05-31
MA38091B1 (fr) 2018-05-31

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