SG11201408123SA - Aminotriazolopyridine for use in the treatment of inflammation, and pharmaceutical compositions thereof - Google Patents

Aminotriazolopyridine for use in the treatment of inflammation, and pharmaceutical compositions thereof

Info

Publication number
SG11201408123SA
SG11201408123SA SG11201408123SA SG11201408123SA SG11201408123SA SG 11201408123S A SG11201408123S A SG 11201408123SA SG 11201408123S A SG11201408123S A SG 11201408123SA SG 11201408123S A SG11201408123S A SG 11201408123SA SG 11201408123S A SG11201408123S A SG 11201408123SA
Authority
SG
Singapore
Prior art keywords
lllll
mechelen
galapagos
international
diseases
Prior art date
Application number
SG11201408123SA
Other languages
English (en)
Inventor
T Klooster Gerben Albert Eleutherius Van
Reginald Christophe Xavier Brys
Rompaey Luc Juliaan Corina Van
Florence Sylvie Namour
Original Assignee
Galapagos Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galapagos Nv filed Critical Galapagos Nv
Publication of SG11201408123SA publication Critical patent/SG11201408123SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11201408123SA 2012-06-22 2013-06-10 Aminotriazolopyridine for use in the treatment of inflammation, and pharmaceutical compositions thereof SG11201408123SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261663520P 2012-06-22 2012-06-22
PCT/EP2013/061914 WO2013189771A1 (en) 2012-06-22 2013-06-10 Aminotriazolopyridine for use in the treatment of inflammation, and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
SG11201408123SA true SG11201408123SA (en) 2015-01-29

Family

ID=48577773

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201408123SA SG11201408123SA (en) 2012-06-22 2013-06-10 Aminotriazolopyridine for use in the treatment of inflammation, and pharmaceutical compositions thereof
SG10201700125VA SG10201700125VA (en) 2012-06-22 2013-06-10 Aminotriazolopyridine For Use In The Treatment Of Inflammation, And Pharmaceutical Compositions Thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201700125VA SG10201700125VA (en) 2012-06-22 2013-06-10 Aminotriazolopyridine For Use In The Treatment Of Inflammation, And Pharmaceutical Compositions Thereof

Country Status (35)

Country Link
US (2) US9284311B2 (ru)
EP (1) EP2863950B1 (ru)
JP (2) JP6238975B2 (ru)
KR (1) KR102078069B1 (ru)
CN (2) CN104379173A (ru)
AR (1) AR091395A1 (ru)
AU (1) AU2013279597B2 (ru)
BR (1) BR112014031626A8 (ru)
CA (1) CA2875619C (ru)
CL (1) CL2014003462A1 (ru)
CO (1) CO7160085A2 (ru)
CR (1) CR20140583A (ru)
CY (1) CY1120643T1 (ru)
DK (1) DK2863950T3 (ru)
EA (1) EA029084B1 (ru)
ES (1) ES2685985T3 (ru)
HK (1) HK1208368A1 (ru)
HR (1) HRP20181364T8 (ru)
HU (1) HUE038878T2 (ru)
IL (1) IL235923B (ru)
LT (1) LT2863950T (ru)
MA (1) MA37775A1 (ru)
MX (1) MX368511B (ru)
MY (1) MY177334A (ru)
NZ (1) NZ702480A (ru)
PE (1) PE20150187A1 (ru)
PH (1) PH12014502615B1 (ru)
PL (1) PL2863950T3 (ru)
PT (1) PT2863950T (ru)
SG (2) SG11201408123SA (ru)
SI (1) SI2863950T1 (ru)
TW (1) TWI586352B (ru)
UA (1) UA112804C2 (ru)
UY (1) UY34855A (ru)
WO (1) WO2013189771A1 (ru)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3041B1 (ar) 2008-07-25 2016-09-05 Galapagos Nv مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
TWI462920B (zh) 2009-06-26 2014-12-01 葛萊伯格有限公司 用於治療退化性及發炎疾病之新穎化合物
GB201402071D0 (en) * 2014-02-07 2014-03-26 Galapagos Nv Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders
GB201402070D0 (en) 2014-02-07 2014-03-26 Galapagos Nv Pharmaceutical compositions for the treatment of inflammatory disorders
PL3283114T3 (pl) * 2015-04-13 2024-01-03 Galapagos Nv Sposoby leczenia zaburzeń sercowo-naczyniowych
WO2016165953A1 (en) 2015-04-13 2016-10-20 Galapagos Nv Methods for the treatment of inflammatory disorders
AU2016257892A1 (en) * 2015-05-05 2017-11-09 Concert Pharmaceuticals, Inc. Deuterated filgotinib
CN105061420B (zh) * 2015-06-04 2017-09-05 南京旗昌医药科技有限公司 一种jak抑制剂的晶型及其制备方法和应用
WO2017106568A1 (en) 2015-12-17 2017-06-22 Gilead Sciences, Inc. Combination of a jak inhibitor and a bromodomain inhibitor for treating cancer
US20170174788A1 (en) 2015-12-17 2017-06-22 Gilead Sciences, Inc. Combination of a jak inhibitor and an mmp9 binding protein for treating inflammatory disorders
WO2017106564A1 (en) 2015-12-17 2017-06-22 Gilead Sciences, Inc. Combination of a jak inhibitor and a syk inhibitor for treating cancers and inflammatory disorders
CN112851682B (zh) * 2016-02-02 2022-10-25 深圳市塔吉瑞生物医药有限公司 一种取代的吡啶酰胺类化合物及其应用
AU2017358703A1 (en) 2016-11-10 2019-05-09 Galapagos Nv Compounds and pharmaceutical compositions thereof for the treatment of inflammatory diseases
GB201702603D0 (en) 2017-02-17 2017-04-05 Galápagos Nv Novel compositions and pharmaceutical compositions thereof for the treatment of inflammatory disorders
GB201808575D0 (en) * 2018-05-24 2018-07-11 Galapagos Nv Methods for the treatment of psoriatic arthrits
WO2019246273A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a jak or other kinase inhibitor
US20220185810A1 (en) * 2019-03-30 2022-06-16 Unichem Laboratories Limited Novel Process for the Preparation of Filgotinib and Intermediates Thereof
JP7315166B2 (ja) * 2019-06-10 2023-07-26 富士通株式会社 グラフェンナノリボンネットワーク膜の製造方法及び電子装置の製造方法
CN111686106B (zh) * 2020-04-05 2022-07-15 温州医科大学附属第一医院 提高Dicer表达的化合物在制备药物中的应用
CN114409675B (zh) * 2022-01-07 2023-08-04 重庆医科大学 螺环异恶唑酮色满衍生物在制备用于治疗jak1介导的疾病药物中的用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007291190A1 (en) * 2006-08-30 2008-03-06 Cellzome Limited Triazole derivatives as kinase inhibitors
TWI453207B (zh) * 2008-09-08 2014-09-21 Signal Pharm Llc 胺基三唑并吡啶,其組合物及使用其之治療方法
CN102459258B (zh) * 2009-06-05 2015-11-25 赛福伦公司 1,2,4-三唑并[1,5a]吡啶衍生物的制备和用途
TWI462920B (zh) * 2009-06-26 2014-12-01 葛萊伯格有限公司 用於治療退化性及發炎疾病之新穎化合物
JO3030B1 (ar) * 2009-06-26 2016-09-05 Galapagos Nv مركب جديد مفيد لمعالجة الامراض التنكسية والالتهابات

Also Published As

Publication number Publication date
TWI586352B (zh) 2017-06-11
PH12014502615A1 (en) 2015-01-21
KR102078069B1 (ko) 2020-02-17
ES2685985T3 (es) 2018-10-15
NZ702480A (en) 2016-11-25
CN104379173A (zh) 2015-02-25
BR112014031626A8 (pt) 2021-10-19
JP6238975B2 (ja) 2017-11-29
DK2863950T3 (en) 2018-09-03
EP2863950B1 (en) 2018-07-18
CA2875619A1 (en) 2013-12-27
UY34855A (es) 2014-01-31
PH12014502615B1 (en) 2015-01-21
CO7160085A2 (es) 2015-01-15
IL235923A0 (en) 2015-01-29
PT2863950T (pt) 2018-10-10
CY1120643T1 (el) 2019-12-11
HUE038878T2 (hu) 2018-12-28
WO2013189771A1 (en) 2013-12-27
AR091395A1 (es) 2015-02-04
US20160296529A1 (en) 2016-10-13
US20130345209A1 (en) 2013-12-26
PL2863950T3 (pl) 2019-02-28
JP2018048185A (ja) 2018-03-29
IL235923B (en) 2018-11-29
SI2863950T1 (sl) 2018-10-30
MX368511B (es) 2019-10-07
SG10201700125VA (en) 2017-02-27
JP2015520198A (ja) 2015-07-16
EP2863950A1 (en) 2015-04-29
PE20150187A1 (es) 2015-02-27
HRP20181364T8 (hr) 2018-12-28
EA201590071A1 (ru) 2015-04-30
EA029084B1 (ru) 2018-02-28
LT2863950T (lt) 2018-09-25
CR20140583A (es) 2015-02-10
MX2014014800A (es) 2015-02-12
CN107998136A (zh) 2018-05-08
AU2013279597B2 (en) 2017-04-20
UA112804C2 (uk) 2016-10-25
MY177334A (en) 2020-09-12
MA37775A1 (fr) 2017-04-28
AU2013279597A1 (en) 2015-01-15
US9284311B2 (en) 2016-03-15
CA2875619C (en) 2020-11-24
TW201400114A (zh) 2014-01-01
HRP20181364T1 (hr) 2018-10-19
HK1208368A1 (en) 2016-03-04
CL2014003462A1 (es) 2015-02-27
KR20150023048A (ko) 2015-03-04
BR112014031626A2 (pt) 2017-06-27

Similar Documents

Publication Publication Date Title
SG11201408123SA (en) Aminotriazolopyridine for use in the treatment of inflammation, and pharmaceutical compositions thereof
SG11201804162WA (en) Compositions comprising bacterial strains
SG11201901141WA (en) Crystalline form of (s)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide, preparation, and uses thereof
SG11201407580YA (en) Composition comprising two antibodies engineered to have reduced and increased effector function
SG11201811490XA (en) Cd3 binding antibodies
SG11201909022PA (en) ANTI-N3pGlu AMYLOID BETA PEPTIDE ANTIBODIES AND USES THEREOF
SG11201804118VA (en) Compositions comprising bacterial strains
SG11201408261UA (en) Syringe
SG11201805940QA (en) Benzopyrazole compounds and analogues thereof
SG11201408821SA (en) Selective pi3k delta inhibitors
SG11201809470RA (en) Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseases in animals
SG11201907435PA (en) Combinations of a 4-pyrimidinesulfamide derivative with active ingredients for the treatment of endothelin related diseases
SG11201407682TA (en) Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
SG11201408318RA (en) Compositions and methods for transmucosal absorption
SG11201906436VA (en) Novel heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same
SG11201906959RA (en) Aryl hydrocarbon receptor (ahr) modulator compounds
SG11201810965YA (en) 1h-pyrazolo[4,3-b]pyridines as pde1 inhibitors
SG11201903061YA (en) Combination treatments comprising administration of imidazopyrazinones
SG11201906222WA (en) Jak1 selective inhibitors
SG11201407575PA (en) 5-amino[1,4]thiazines as bace 1 inhibitors
SG11201805311XA (en) Method of treating a mammal, including human, against cancer using methionine and asparagine depletion
SG11201805941WA (en) Tgfbeta 2 antibodies
SG11201806424TA (en) Therapeutic compounds
SG11201407812SA (en) Methods for reducing levels of protein-contaminant complexes and aggregates in protein preparations by treatment with electropositive organic additives
SG11201901438VA (en) Solid forms of cenicriviroc mesylate and processes of making solid forms of cenicriviroc mesylate