SG11201405218RA - Method of preparing an artificial tooth primordium in vitro and artificial tooth primordium derived therefrom - Google Patents
Method of preparing an artificial tooth primordium in vitro and artificial tooth primordium derived therefromInfo
- Publication number
- SG11201405218RA SG11201405218RA SG11201405218RA SG11201405218RA SG11201405218RA SG 11201405218R A SG11201405218R A SG 11201405218RA SG 11201405218R A SG11201405218R A SG 11201405218RA SG 11201405218R A SG11201405218R A SG 11201405218RA SG 11201405218R A SG11201405218R A SG 11201405218RA
- Authority
- SG
- Singapore
- Prior art keywords
- artificial tooth
- tooth primordium
- vitro
- preparing
- derived therefrom
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3865—Dental/periodontal tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3821—Bone-forming cells, e.g. osteoblasts, osteocytes, osteoprogenitor cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0664—Dental pulp stem cells, Dental follicle stem cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
- C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1361—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from dental pulp or dental follicle stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2513/00—3D culture
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Developmental Biology & Embryology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12157470.1A EP2633870B1 (fr) | 2012-02-29 | 2012-02-29 | Procédé de préparation d'ébauche de dent artificielle in vitro et ébauche de dent artificielle dérivée de celui-ci |
PCT/EP2013/053361 WO2013127671A1 (fr) | 2012-02-29 | 2013-02-20 | Procédé de préparation d'une ébauche dentaire artificielle in vitro et ébauche dentaire artificielle ainsi obtenue |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201405218RA true SG11201405218RA (en) | 2014-11-27 |
Family
ID=47722304
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201405218RA SG11201405218RA (en) | 2012-02-29 | 2013-02-20 | Method of preparing an artificial tooth primordium in vitro and artificial tooth primordium derived therefrom |
Country Status (7)
Country | Link |
---|---|
US (2) | US20140377233A1 (fr) |
EP (1) | EP2633870B1 (fr) |
CN (1) | CN104271167B (fr) |
HK (1) | HK1205006A1 (fr) |
RU (1) | RU2638783C2 (fr) |
SG (1) | SG11201405218RA (fr) |
WO (1) | WO2013127671A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104274861A (zh) * | 2014-07-25 | 2015-01-14 | 上海国睿生命科技有限公司 | 一种牙髓牙本质再生的可注射组织工程构建方法 |
IL261623B2 (en) * | 2016-03-09 | 2024-03-01 | Avita Int Ltd | Stem cells expressing mesenchymal and neuronal markers, compositions containing them and methods for their preparation |
EP3443065A1 (fr) * | 2016-04-13 | 2019-02-20 | Corning Incorporated | Revêtement de surface biocompatible présentant des propriétés de mouillabilité de surface élevées |
KR102163471B1 (ko) * | 2018-08-14 | 2020-10-08 | 단국대학교 천안캠퍼스 산학협력단 | 에나멜 전구 세포 판별용 바이오 마커 조성물 |
KR102218667B1 (ko) * | 2019-08-16 | 2021-02-22 | 차의과학대학교 산학협력단 | 치수 줄기세포를 포함하는 치아 유사 오가노이드의 제조방법 및 이의 용도 |
CN115992215A (zh) * | 2022-09-22 | 2023-04-21 | 中南大学 | 非综合征型先天缺牙基因突变位点及其应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4414644A1 (de) | 1993-10-29 | 1995-05-04 | Bosch Gmbh Robert | Fahrzeugsicherungsanordnung |
ES2423898T3 (es) * | 2000-07-21 | 2013-09-25 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Citoblastos de pulpa dental de seres humanos adultos in vitro e in vivo |
ATE397654T1 (de) * | 2002-02-06 | 2008-06-15 | Stiftung Caesar | Aus zähnen gewonnene pluripotente embryonalähnliche stammzellen und verwendungen davon |
GB0304030D0 (en) * | 2003-02-21 | 2003-03-26 | King S College London | Teeth |
JP2004331557A (ja) | 2003-05-07 | 2004-11-25 | Hitachi Medical Corp | 歯胚の再生方法 |
FI20031724A0 (fi) | 2003-11-25 | 2003-11-25 | Timo Kalevi Korpela | Menetelmä hammaselimen regeneroimiseksi |
WO2006129672A1 (fr) | 2005-05-30 | 2006-12-07 | Tokyo University Of Science Educational Foundation Administrative Organization | Méthode pour produire une dent et méthode pour produire des dents et du tissu |
US20100093080A1 (en) * | 2005-07-29 | 2010-04-15 | Matsumoto Dental University | Tooth Regeneration Method |
WO2007136760A2 (fr) | 2006-05-19 | 2007-11-29 | The Johns Hopkins University | Procédé de croissance de cellules mésenchymales dans des conditions de non adhérence à des fins d'applications cliniques |
CN101842477B (zh) * | 2007-01-22 | 2013-03-27 | 株式会社器官再生工学 | 间充质细胞的制造方法、牙的制造方法及牙形成用间充质细胞 |
JP2008206500A (ja) | 2007-02-28 | 2008-09-11 | Tokyo Univ Of Science | 歯の製造方法及びこれにより得られた歯 |
CN101318032B (zh) * | 2007-06-06 | 2012-11-21 | 李京倖 | 小口径组织工程学人工血管及其制备方法 |
RU2517046C2 (ru) | 2008-06-04 | 2014-05-27 | Тиссюз Гмбх | Устройство "орган-на-чипе" |
ITRM20080342A1 (it) * | 2008-06-26 | 2009-12-27 | Univ Degli Studi Udine | Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso. |
TW201014912A (en) | 2008-08-20 | 2010-04-16 | Organ Technologies Inc | Method for repairing a lost portion of a tooth and method for preparing a repair material used in the same |
US20100172951A1 (en) * | 2009-01-03 | 2010-07-08 | Ray Wasielewski | Enhanced Medical Implant |
CN101579537B (zh) * | 2009-07-07 | 2010-09-01 | 中国人民解放军第四军医大学 | 一种组织工程化生物活性种植体表面处理方法 |
-
2012
- 2012-02-29 EP EP12157470.1A patent/EP2633870B1/fr active Active
-
2013
- 2013-02-20 RU RU2014135202A patent/RU2638783C2/ru active
- 2013-02-20 WO PCT/EP2013/053361 patent/WO2013127671A1/fr active Application Filing
- 2013-02-20 US US14/381,660 patent/US20140377233A1/en not_active Abandoned
- 2013-02-20 CN CN201380011350.1A patent/CN104271167B/zh active Active
- 2013-02-20 SG SG11201405218RA patent/SG11201405218RA/en unknown
-
2015
- 2015-06-12 HK HK15105608.6A patent/HK1205006A1/xx unknown
-
2019
- 2019-01-18 US US16/251,560 patent/US11578308B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN104271167B (zh) | 2016-10-26 |
US20140377233A1 (en) | 2014-12-25 |
WO2013127671A1 (fr) | 2013-09-06 |
US20190185815A1 (en) | 2019-06-20 |
RU2638783C2 (ru) | 2017-12-15 |
US11578308B2 (en) | 2023-02-14 |
CN104271167A (zh) | 2015-01-07 |
HK1205006A1 (en) | 2015-12-11 |
EP2633870A1 (fr) | 2013-09-04 |
EP2633870B1 (fr) | 2018-08-01 |
RU2014135202A (ru) | 2016-04-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB201223202D0 (en) | Abutment and method of attaching an abutment to a dental implant | |
GB2479018B (en) | Artificial eyelash structure and its fabrication and method of use | |
EP2900181A4 (fr) | Implants programmables et procédés d'utilisation d'implants programmables pour réparer des structures osseuses | |
EP2773287A4 (fr) | Prothèse personnalisée et procédés d'utilisation | |
IL230855A0 (en) | Cabazitaxel formulations and methods for their preparation | |
EP2716798A4 (fr) | Fibre polypeptidique artificielle et procédé pour la produire | |
EP2897551A4 (fr) | Gabarits pour positionner des analogues d'implant dentaire dans des modèles et procédés de réalisation associés | |
EP2579819A4 (fr) | Composants d'implant et procédés associés | |
HK1250669A1 (zh) | 植入物和用於生產植入物的方法 | |
ZA201506836B (en) | Composition of artificial hair and production method thereof | |
EP2692858A4 (fr) | Procédé de fabrication d'un modèle de peau artificiel, et modèle de peau artificiel | |
EP2887997A4 (fr) | Réduction de sons transitoires dans des implants auditifs | |
HK1205006A1 (en) | Method of preparing an artificial tooth primordium in vitro and artificial tooth primordium derived therefrom | |
GB2487055B (en) | Artificial eyes and manufacture thereof | |
EP2472003A4 (fr) | Cuir artificiel à fibre superfine et procédé de préparation de ce dernier | |
HK1201141A1 (en) | Dental implant and method for producing a dental implant | |
SG11201404500SA (en) | Dental implant and method for producing same | |
ZA201200971B (en) | Artificial nail or tip arrangement and method of making same | |
GB201200458D0 (en) | Methods of preparing cells and compositions | |
HK1177699A1 (en) | Artificial skin and manufacturing method thereof | |
EP2680787A4 (fr) | Implant chirurgical et procédé associé | |
EP2881079A4 (fr) | Système de prothèse hybride par implant, et implant | |
EP2882401A4 (fr) | Matériaux dentaires et procédé de fabrication associé | |
PL2844185T3 (pl) | Sposób wykonywania protezy zębowej i artykulator do przeprowadzenia tego sposobu | |
GB201117106D0 (en) | Prosthesis and methods and uses involving said prosthesis |