SG11201401291XA - Adjuvant compound - Google Patents

Adjuvant compound

Info

Publication number
SG11201401291XA
SG11201401291XA SG11201401291XA SG11201401291XA SG11201401291XA SG 11201401291X A SG11201401291X A SG 11201401291XA SG 11201401291X A SG11201401291X A SG 11201401291XA SG 11201401291X A SG11201401291X A SG 11201401291XA SG 11201401291X A SG11201401291X A SG 11201401291XA
Authority
SG
Singapore
Prior art keywords
adjuvant compound
adjuvant
compound
Prior art date
Application number
SG11201401291XA
Other languages
English (en)
Inventor
Ferdinand Antonius Ossendorp
Cornelis Johannes Maria Melief
Selina Khan
Dmitri Viktorovitsj Filippov
Der Marel Gijsbert Arie Van
Original Assignee
Isa Pharmaceuticals B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isa Pharmaceuticals B V filed Critical Isa Pharmaceuticals B V
Publication of SG11201401291XA publication Critical patent/SG11201401291XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55516Proteins; Peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
SG11201401291XA 2011-10-05 2012-10-04 Adjuvant compound SG11201401291XA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161543510P 2011-10-05 2011-10-05
NL2007536A NL2007536C2 (en) 2011-10-05 2011-10-05 Adjuvant compound.
US201261615566P 2012-03-26 2012-03-26
PCT/NL2012/050694 WO2013051936A1 (en) 2011-10-05 2012-10-04 Adjuvant compound

Publications (1)

Publication Number Publication Date
SG11201401291XA true SG11201401291XA (en) 2014-05-29

Family

ID=48043964

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201401291XA SG11201401291XA (en) 2011-10-05 2012-10-04 Adjuvant compound

Country Status (16)

Country Link
US (2) US9314521B2 (OSRAM)
EP (1) EP2763697B9 (OSRAM)
JP (1) JP6099210B2 (OSRAM)
KR (1) KR102053699B1 (OSRAM)
CN (1) CN104244976B (OSRAM)
AU (1) AU2012319265B2 (OSRAM)
BR (1) BR112014008214B1 (OSRAM)
CA (1) CA2886631C (OSRAM)
EA (1) EA030741B1 (OSRAM)
ES (1) ES2952644T3 (OSRAM)
IL (1) IL231951B (OSRAM)
IN (1) IN2014DN03325A (OSRAM)
MX (1) MX356028B (OSRAM)
NL (1) NL2007536C2 (OSRAM)
SG (1) SG11201401291XA (OSRAM)
WO (1) WO2013051936A1 (OSRAM)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014234314B2 (en) 2013-03-21 2018-02-15 Sanofi-Aventis Deutschland Gmbh Synthesis of cyclic imide containing peptide products
SG11201506804VA (en) 2013-03-21 2015-09-29 Sanofi Aventis Deutschland Synthesis of hydantoin containing peptide products
AU2014300503B2 (en) 2013-06-28 2018-11-22 Auckland Uniservices Limited Amino acid and peptide conjugates and conjugation process
JP6780852B2 (ja) 2014-06-02 2020-11-04 アイエスエー ファーマシューティカルズ ビー.ヴイ.ISA Pharmaceuticals B.V. B型肝炎ウイルス感染に対する治療ワクチン接種のための合成長鎖ペプチド(slp)
RU2017126206A (ru) 2014-12-23 2019-01-25 Маргарет Анне БРИМБЛЕ Аминокислотные и пептидные конъюгаты и направления их использования
PE20230343A1 (es) 2015-12-11 2023-03-01 Immatics Biotechnologies Gmbh Peptidos que estimulan respuestas inmunitarias antitumorales
GB201521894D0 (en) * 2015-12-11 2016-01-27 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against various cancers
KR20180128915A (ko) 2016-02-26 2018-12-04 오클랜드 유니서비시즈 리미티드 아미노산 및 펩티드 접합체 및 접합 방법
WO2017220463A1 (en) 2016-06-20 2017-12-28 Isa Pharmaceuticals B.V. Formulation of a peptide vaccine
WO2018009916A1 (en) 2016-07-07 2018-01-11 The Board Of Trustees Of The Leland Stanford Junior University Antibody adjuvant conjugates
EP3606551A1 (en) 2017-04-04 2020-02-12 Avidea Technologies, Inc. Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response
WO2019122050A1 (en) 2017-12-22 2019-06-27 Isa Pharmaceuticals B.V. Methods of immunization
AU2020241686A1 (en) 2019-03-15 2021-11-04 Bolt Biotherapeutics, Inc. Immunoconjugates targeting HER2
CN115003685A (zh) 2019-12-07 2022-09-02 Isa制药有限公司 乙型肝炎病毒相关疾病的治疗
WO2021156404A2 (en) 2020-02-07 2021-08-12 Isa Pharmaceuticals Treatment of hpv-related diseases
EP4138876A1 (en) 2020-04-23 2023-03-01 ISA Pharmaceuticals B.V. Immunization against sars-cov-related diseases
CA3223357A1 (en) 2021-07-12 2023-01-19 Brigitte Elisa Anna Burm Improved substance quantification in complex mixtures
WO2024068636A1 (en) 2022-09-27 2024-04-04 Isa Pharmaceuticals B.V. Adjuvanted immunogenic peptides for intradermal administration
EP4601685A1 (en) 2022-10-13 2025-08-20 Isabella Pharma B.V. Modified long peptides suitable for use in immunisation
WO2024149888A1 (en) 2023-01-12 2024-07-18 Isa Pharmaceuticals B.V. Improved lipopeptide quantification
WO2025008085A1 (en) 2023-07-05 2025-01-09 Isa Pharmaceuticals B.V. Immunotherapy for the treatment of prame-expressing cancers

Family Cites Families (17)

* Cited by examiner, † Cited by third party
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EP0114787B1 (de) * 1983-01-25 1991-09-25 Ciba-Geigy Ag Neue Peptidderivate
DE3937412A1 (de) * 1989-11-10 1991-05-16 Hoechst Ag Synthetische vakzine zur spezifischen induktion zytotoxischer t-lymphozyten
US6024964A (en) * 1985-06-24 2000-02-15 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
US5804381A (en) 1996-10-03 1998-09-08 Cornell Research Foundation Isolated nucleic acid molecule encoding an esophageal cancer associated antigen, the antigen itself, and uses thereof
US20030211510A1 (en) 1999-06-30 2003-11-13 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US6504010B1 (en) 1999-06-30 2003-01-07 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US6686447B1 (en) 1999-06-30 2004-02-03 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
HUP0201757A3 (en) 1999-06-30 2010-01-28 Corixa Corp Compositoins and methods for the therapy and diagnosis of lung cancer
NL1012739C2 (nl) 1999-07-29 2001-01-30 Maasland Nv Voerinrichting, in het bijzonder voor het verstrekken van krachtvoer.
AU2002219711B8 (en) 2000-12-08 2006-03-02 Academisch Ziekenhuis Leiden Long peptides of 22-45 amino acid residues that induce and/or enhance antigen specific immune responses
MXNL04000056A (es) 2004-06-30 2006-01-11 Mario Alberto Aguilera Rico Sistema de construccion terra acero.
JP2010500407A (ja) * 2006-08-14 2010-01-07 サイモン・エル・エル・シー Hiv−1の複数の株及びサブタイプを治療及び予防するための組成物及び方法
JP5649952B2 (ja) 2007-03-26 2015-01-07 アカデミシュ・ジーケンフイス・レイデン・エイチ.オー.デー.エヌ.・エルユーエムシーAcademisch Ziekenhuis Leiden h.o.d.n. LUMC Prame由来ペプチド及びこれらを含んでいる免疫原性組成物
CA2689536A1 (en) 2007-05-31 2008-12-04 Academisch Ziekenhuis Leiden H.O.D.N. Lumc P53 peptide vaccine
ES2411059T3 (es) 2007-05-31 2013-07-04 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Epítopos de HPV objetivos de células T que infiltran malignidades cervicales para su uso en vacunas
KR100900837B1 (ko) 2007-12-07 2009-06-04 (주)두비엘 리포펩타이드와 폴리(i:c)를 아쥬반트로 포함하는 강력한백신 조성물
KR101853513B1 (ko) * 2010-03-23 2018-04-30 노파르티스 아게 감염, 염증, 호흡기 질환 등의 치료를 위해 사용되는 tlr2 효능제로서의 화합물 (시스테인 기재 리포펩티드) 및 조성물

Also Published As

Publication number Publication date
NL2007536C2 (en) 2013-04-08
MX356028B (es) 2018-05-09
CN104244976A (zh) 2014-12-24
CN104244976B (zh) 2017-05-31
IL231951A0 (en) 2014-05-28
EP2763697C0 (en) 2023-06-07
KR102053699B1 (ko) 2019-12-09
US9314521B2 (en) 2016-04-19
AU2012319265A1 (en) 2014-05-22
EA201490709A1 (ru) 2014-09-30
ES2952644T3 (es) 2023-11-02
EP2763697B1 (en) 2023-06-07
EP2763697A1 (en) 2014-08-13
WO2013051936A9 (en) 2013-09-12
US20160250325A1 (en) 2016-09-01
AU2012319265B2 (en) 2016-10-13
WO2013051936A1 (en) 2013-04-11
MX2014004114A (es) 2014-10-17
NZ623869A (en) 2015-11-27
US9770506B2 (en) 2017-09-26
JP2014530808A (ja) 2014-11-20
EP2763697B9 (en) 2023-10-04
US20150104473A1 (en) 2015-04-16
KR20140093673A (ko) 2014-07-28
BR112014008214B1 (pt) 2022-07-05
EA030741B1 (ru) 2018-09-28
IL231951B (en) 2019-08-29
JP6099210B2 (ja) 2017-03-22
BR112014008214A2 (pt) 2017-06-13
IN2014DN03325A (OSRAM) 2015-06-26
CA2886631C (en) 2019-06-11
EP2763697B8 (en) 2023-07-12
CA2886631A1 (en) 2013-04-11

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