SG11201401268RA - Assays for identifying compounds that modulate bitter taste - Google Patents
Assays for identifying compounds that modulate bitter tasteInfo
- Publication number
- SG11201401268RA SG11201401268RA SG11201401268RA SG11201401268RA SG11201401268RA SG 11201401268R A SG11201401268R A SG 11201401268RA SG 11201401268R A SG11201401268R A SG 11201401268RA SG 11201401268R A SG11201401268R A SG 11201401268RA SG 11201401268R A SG11201401268R A SG 11201401268RA
- Authority
- SG
- Singapore
- Prior art keywords
- assays
- bitter taste
- identifying compounds
- modulate bitter
- modulate
- Prior art date
Links
- 238000003556 assay Methods 0.000 title 1
- 235000019658 bitter taste Nutrition 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Endocrinology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Seasonings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161549693P | 2011-10-20 | 2011-10-20 | |
| PCT/US2012/061400 WO2013059836A1 (en) | 2011-10-20 | 2012-10-22 | Assays for identifying compounds that modulate bitter taste |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201401268RA true SG11201401268RA (en) | 2014-05-29 |
Family
ID=48141484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201401268RA SG11201401268RA (en) | 2011-10-20 | 2012-10-22 | Assays for identifying compounds that modulate bitter taste |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9347934B2 (enExample) |
| EP (1) | EP2769216B1 (enExample) |
| JP (1) | JP6122858B2 (enExample) |
| CN (1) | CN103998933B (enExample) |
| IN (1) | IN2014MN00714A (enExample) |
| SG (1) | SG11201401268RA (enExample) |
| WO (1) | WO2013059836A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9927424B2 (en) | 2013-04-24 | 2018-03-27 | Chromocell Corporation | Assays for identifying compounds that modulate bitter taste |
| WO2017019890A1 (en) * | 2015-07-28 | 2017-02-02 | Mars, Incorporated | Screening methods using canine t2r receptors and pet food products and compositions identified using the same |
| CN112442107B (zh) * | 2020-11-18 | 2023-05-09 | 渤海大学 | 一种苦味抑制肽及其应用 |
| EP4298209A1 (en) * | 2021-05-07 | 2024-01-03 | Firmenich Incorporated | Cells expressing bitter taste receptors and uses thereof |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL118460A (en) * | 1996-05-28 | 1999-09-22 | Dead Sea Works Ltd | Edible salt mixture |
| JP2002533693A (ja) | 1998-12-23 | 2002-10-08 | マウント シナイ スクール オブ メディシン オブ ニューヨーク ユニバーシティー | 苦味応答のインヒビター |
| US6692965B1 (en) | 1999-11-23 | 2004-02-17 | Chromocell Corporation | Isolation of living cells and preparation of cell lines based on detection and quantification of preselected cellular ribonucleic acid sequences |
| CN1341632A (zh) * | 2000-09-05 | 2002-03-27 | 上海博德基因开发有限公司 | 一种新的多肽——人味觉感受器蛋白t2r6－17.05和编码这种多肽的多核苷酸 |
| US7883856B2 (en) | 2001-04-05 | 2011-02-08 | Senomyx Inc. | Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators |
| US8030008B2 (en) * | 2001-04-05 | 2011-10-04 | Senomyx, Inc. | Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators |
| EP2270155A3 (en) | 2002-09-25 | 2011-08-10 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke | Bitter taste receptors |
| ATE540128T1 (de) | 2004-02-18 | 2012-01-15 | Chromocell Corp | Verfahren und materialien unter anwendung von signalsonden |
| EP1815015B1 (en) | 2004-11-18 | 2012-05-23 | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke Stiftung des Öffentlichen Rechts | Agonists of bitter taste receptors and uses thereof |
| CA2612561A1 (en) | 2005-06-22 | 2007-01-04 | Senomyx, Inc. | Identification of human t2r recepors that are activated by bitter molecules in coffee (chlorogenic lactones) and related assays for identifying human bitter taste modulators |
| US7923047B2 (en) * | 2006-06-30 | 2011-04-12 | Conagra Foods Rdm, Inc. | Seasoning and method for seasoning a food product while reducing dietary sodium intake |
| US20080167286A1 (en) * | 2006-12-12 | 2008-07-10 | Abbott Laboratories | Pharmaceutical compositions and their methods of use |
| WO2008119196A1 (en) | 2007-03-30 | 2008-10-09 | Givaudan Sa | Off-note blocking sensory organic compounds |
| CN101652342B (zh) | 2007-03-30 | 2014-01-29 | 奇华顿股份有限公司 | 遮蔽不适感感觉的有机化合物 |
| US8187822B2 (en) * | 2007-03-30 | 2012-05-29 | Givaudan S.A. | Methods to identify modulators |
| EP1983342A1 (en) * | 2007-04-18 | 2008-10-22 | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand | Antogonists of bitter taste receptors and uses thereof |
| US20100311786A1 (en) | 2007-07-30 | 2010-12-09 | Givaudan Sa | Mono- or bicyclic carboxylic acids as off-note blockers |
| CN101828111B (zh) * | 2007-08-21 | 2014-07-23 | 塞诺米克斯公司 | 人t2r苦味受体及其用途 |
| AU2009215106B2 (en) | 2008-02-01 | 2015-07-23 | Chromocell Corporation | Cell lines and methods for making and using them |
| US8546085B2 (en) * | 2008-06-13 | 2013-10-01 | Givaudan Sa | Methods of identifying modulators of the bitter taste receptor TAS2R44 |
| WO2010015097A1 (en) * | 2008-08-07 | 2010-02-11 | Givaudan Sa | Methods to identify modulators of the interaction between dextromethorphan and the bitter taste receptor tas2r46 |
| KR101751074B1 (ko) | 2009-02-02 | 2017-06-26 | 크로모셀 코포레이션 | 신규한 세포주와 방법 |
| WO2010099983A1 (en) * | 2009-03-06 | 2010-09-10 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke | Methods for isolating agonists and antagonists of taste receptors |
| US20130040317A1 (en) | 2011-08-08 | 2013-02-14 | The University Of North Carolina At Chapel Hill | Cell lines comprising endogenous taste receptors and their uses |
-
2012
- 2012-10-22 IN IN714MUN2014 patent/IN2014MN00714A/en unknown
- 2012-10-22 US US14/352,620 patent/US9347934B2/en not_active Expired - Fee Related
- 2012-10-22 SG SG11201401268RA patent/SG11201401268RA/en unknown
- 2012-10-22 CN CN201280062863.0A patent/CN103998933B/zh not_active Expired - Fee Related
- 2012-10-22 EP EP12841448.9A patent/EP2769216B1/en not_active Not-in-force
- 2012-10-22 JP JP2014537371A patent/JP6122858B2/ja active Active
- 2012-10-22 WO PCT/US2012/061400 patent/WO2013059836A1/en not_active Ceased
-
2016
- 2016-04-21 US US15/135,145 patent/US20160299127A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20160299127A1 (en) | 2016-10-13 |
| US20140248639A1 (en) | 2014-09-04 |
| EP2769216A1 (en) | 2014-08-27 |
| CN103998933B (zh) | 2016-12-14 |
| EP2769216A4 (en) | 2015-05-13 |
| CN103998933A (zh) | 2014-08-20 |
| JP2014530628A (ja) | 2014-11-20 |
| WO2013059836A1 (en) | 2013-04-25 |
| IN2014MN00714A (enExample) | 2015-07-03 |
| JP6122858B2 (ja) | 2017-04-26 |
| US9347934B2 (en) | 2016-05-24 |
| EP2769216B1 (en) | 2017-01-04 |
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