SG11201508572UA - Assays for identifying compounds that modulate bitter taste - Google Patents
Assays for identifying compounds that modulate bitter tasteInfo
- Publication number
- SG11201508572UA SG11201508572UA SG11201508572UA SG11201508572UA SG11201508572UA SG 11201508572U A SG11201508572U A SG 11201508572UA SG 11201508572U A SG11201508572U A SG 11201508572UA SG 11201508572U A SG11201508572U A SG 11201508572UA SG 11201508572U A SG11201508572U A SG 11201508572UA
- Authority
- SG
- Singapore
- Prior art keywords
- assays
- bitter taste
- identifying compounds
- modulate bitter
- modulate
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Seasonings (AREA)
- General Preparation And Processing Of Foods (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361815592P | 2013-04-24 | 2013-04-24 | |
| PCT/US2014/035147 WO2014176336A1 (en) | 2013-04-24 | 2014-04-23 | Assays for identifying compounds that modulate bitter taste |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201508572UA true SG11201508572UA (en) | 2015-11-27 |
Family
ID=51792362
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201508572UA SG11201508572UA (en) | 2013-04-24 | 2014-04-23 | Assays for identifying compounds that modulate bitter taste |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9927424B2 (en) |
| EP (1) | EP2989464B1 (en) |
| JP (1) | JP2016523512A (en) |
| CN (1) | CN105358983B (en) |
| AU (1) | AU2014257086A1 (en) |
| BR (1) | BR112015026901A2 (en) |
| CA (1) | CA2910161A1 (en) |
| MX (1) | MX2015014825A (en) |
| RU (1) | RU2015144371A (en) |
| SG (1) | SG11201508572UA (en) |
| WO (1) | WO2014176336A1 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180372721A1 (en) * | 2015-07-28 | 2018-12-27 | Mars, Incorporated | Screening methods using canine t2r receptors and pet food products and compositions identified using the same |
| CN110553983B (en) * | 2019-09-05 | 2022-03-04 | 东北农业大学 | Method for rapidly detecting potassium sorbate in milk |
| BR112022001671A2 (en) * | 2019-09-09 | 2022-03-22 | Firmenich Incorporated | Bitter taste receptor blockers and methods of identifying them |
| CN115443068A (en) | 2020-04-29 | 2022-12-06 | 荷兰邦奇洛德斯克罗科兰有限公司 | Compositions, confectionery products and methods |
| CN112521449B (en) * | 2020-11-18 | 2022-04-22 | 渤海大学 | Two active peptides with bitter taste inhibiting effect |
| WO2023205647A1 (en) * | 2022-04-19 | 2023-10-26 | Firmenich Incorporated | Reduction of bitter taste of active pharmaceutical ingredients and related assays and screening methods |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL118460A (en) | 1996-05-28 | 1999-09-22 | Dead Sea Works Ltd | Edible salt mixture |
| ES2337322T3 (en) | 1998-12-23 | 2010-04-22 | Mount Sinai School Of Medicine Of New York University | INHIBITORS OF THE AMARGO FLAVOR RESPONSE. |
| US6692965B1 (en) | 1999-11-23 | 2004-02-17 | Chromocell Corporation | Isolation of living cells and preparation of cell lines based on detection and quantification of preselected cellular ribonucleic acid sequences |
| CN101397563A (en) * | 2000-04-07 | 2009-04-01 | 塞诺米克斯公司 | T2r taste receptors and genes encoding same |
| US7883856B2 (en) | 2001-04-05 | 2011-02-08 | Senomyx Inc. | Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators |
| US8030008B2 (en) * | 2001-04-05 | 2011-10-04 | Senomyx, Inc. | Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators |
| US20030039968A1 (en) | 2001-07-10 | 2003-02-27 | Applera Corporation | Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof |
| JP4551656B2 (en) * | 2001-07-10 | 2010-09-29 | セノミックス インコーポレイテッド | Use of specific T2R taste receptors to identify compounds that block bitterness |
| DE60330159D1 (en) | 2002-09-25 | 2009-12-31 | Deutsches Inst Ernaehrungsfors | BITTER TASTE RECEPTORS |
| NZ597400A (en) | 2004-02-18 | 2013-06-28 | Chromocell Corp | Methods and Materials Using Signaling Probes |
| WO2006053771A2 (en) | 2004-11-18 | 2006-05-26 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke Stiftung Des Öffentlichen Rechts | Agonists of bitter taste receptors and uses thereof |
| JP2009501317A (en) | 2005-06-22 | 2009-01-15 | セノミクス・インコーポレーテッド | Identification of human T2R receptors activated by bitter taste molecules (chlorogenic acid lactones) in coffee, and related assays for identifying human bitter taste modulators |
| US7923047B2 (en) | 2006-06-30 | 2011-04-12 | Conagra Foods Rdm, Inc. | Seasoning and method for seasoning a food product while reducing dietary sodium intake |
| US20080167286A1 (en) | 2006-12-12 | 2008-07-10 | Abbott Laboratories | Pharmaceutical compositions and their methods of use |
| BRPI0809856B1 (en) | 2007-03-30 | 2016-08-23 | Givaudan Sa | bitter off-note blocking compound, flavor composition, consumable and consumable banknote locking method |
| CN101652342B (en) * | 2007-03-30 | 2014-01-29 | 奇华顿股份有限公司 | Off-note blocking sensory organic compounds |
| KR20100016044A (en) | 2007-03-30 | 2010-02-12 | 지보당 에스아 | Methods to identify modulators |
| EP1983342A1 (en) | 2007-04-18 | 2008-10-22 | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand | Antogonists of bitter taste receptors and uses thereof |
| CN101355441B (en) | 2007-07-27 | 2012-04-04 | 华为技术有限公司 | Method, system and equipment for configuring operation management maintain attribute |
| US8076491B2 (en) * | 2007-08-21 | 2011-12-13 | Senomyx, Inc. | Compounds that inhibit (block) bitter taste in composition and use thereof |
| NZ586957A (en) | 2008-02-01 | 2014-03-28 | Chromocell Corp | Cell lines and methods for making and using them |
| EP2300830B1 (en) | 2008-06-13 | 2015-05-20 | Givaudan SA | Methods of identifying modulators of the bitter taste receptor tas2r44 |
| US8603762B2 (en) | 2008-08-07 | 2013-12-10 | Givaudan Sa | Methods to identify modulators of the interaction between dextromethorphan and the bitter taste receptor TAS2R46 |
| CN102369275A (en) | 2009-02-02 | 2012-03-07 | 卓莫赛尔公司 | Novel cell lines and methods |
| EP2404172A1 (en) | 2009-03-06 | 2012-01-11 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke | Methods for isolating agonists and antagonists of taste receptors |
| US8673578B2 (en) * | 2009-10-27 | 2014-03-18 | Deutsches Institut für Ernahrungsforschung Potsdam-Rehbrücke | Methods of identifying antagonists of the hTAS2R46 bitter taste receptor |
| EP2742349A1 (en) | 2011-08-08 | 2014-06-18 | The Coca-Cola Company | Cell lines comprising endogenous taste receptors and their uses |
| JP6122858B2 (en) * | 2011-10-20 | 2017-04-26 | クロモセル コーポレーション | Assays to identify compounds that modulate bitterness |
-
2014
- 2014-04-23 CN CN201480036118.8A patent/CN105358983B/en not_active Expired - Fee Related
- 2014-04-23 MX MX2015014825A patent/MX2015014825A/en unknown
- 2014-04-23 JP JP2016510756A patent/JP2016523512A/en active Pending
- 2014-04-23 RU RU2015144371A patent/RU2015144371A/en not_active Application Discontinuation
- 2014-04-23 WO PCT/US2014/035147 patent/WO2014176336A1/en active Application Filing
- 2014-04-23 BR BR112015026901A patent/BR112015026901A2/en not_active Application Discontinuation
- 2014-04-23 AU AU2014257086A patent/AU2014257086A1/en not_active Abandoned
- 2014-04-23 CA CA2910161A patent/CA2910161A1/en not_active Abandoned
- 2014-04-23 EP EP14787491.1A patent/EP2989464B1/en not_active Not-in-force
- 2014-04-23 SG SG11201508572UA patent/SG11201508572UA/en unknown
- 2014-04-23 US US14/786,876 patent/US9927424B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2910161A1 (en) | 2014-10-30 |
| RU2015144371A (en) | 2017-05-29 |
| JP2016523512A (en) | 2016-08-12 |
| BR112015026901A2 (en) | 2017-11-14 |
| US9927424B2 (en) | 2018-03-27 |
| AU2014257086A1 (en) | 2015-11-12 |
| US20160069860A1 (en) | 2016-03-10 |
| CN105358983A (en) | 2016-02-24 |
| CN105358983B (en) | 2018-08-03 |
| EP2989464B1 (en) | 2018-12-26 |
| EP2989464A4 (en) | 2016-12-07 |
| WO2014176336A1 (en) | 2014-10-30 |
| MX2015014825A (en) | 2016-05-31 |
| EP2989464A1 (en) | 2016-03-02 |
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