SG11201400828RA - Compositions and methods for treating presbyopia, mild hyperopia, and irregular astigmatism - Google Patents

Compositions and methods for treating presbyopia, mild hyperopia, and irregular astigmatism

Info

Publication number
SG11201400828RA
SG11201400828RA SG11201400828RA SG11201400828RA SG11201400828RA SG 11201400828R A SG11201400828R A SG 11201400828RA SG 11201400828R A SG11201400828R A SG 11201400828RA SG 11201400828R A SG11201400828R A SG 11201400828RA SG 11201400828R A SG11201400828R A SG 11201400828RA
Authority
SG
Singapore
Prior art keywords
compositions
methods
irregular astigmatism
treating presbyopia
mild hyperopia
Prior art date
Application number
SG11201400828RA
Other languages
English (en)
Inventor
Jaun Carlos Abad
Original Assignee
Altavista Inst De Invest Medica S A S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47522725&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201400828R(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Altavista Inst De Invest Medica S A S filed Critical Altavista Inst De Invest Medica S A S
Publication of SG11201400828RA publication Critical patent/SG11201400828RA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
SG11201400828RA 2011-09-20 2012-09-19 Compositions and methods for treating presbyopia, mild hyperopia, and irregular astigmatism SG11201400828RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161536921P 2011-09-20 2011-09-20
PCT/IB2012/002335 WO2013041967A2 (en) 2011-09-20 2012-09-19 Compositions and methods for treating presbyopia, mild hyperopia, and irregular astigmatism

Publications (1)

Publication Number Publication Date
SG11201400828RA true SG11201400828RA (en) 2014-07-30

Family

ID=47522725

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201400828RA SG11201400828RA (en) 2011-09-20 2012-09-19 Compositions and methods for treating presbyopia, mild hyperopia, and irregular astigmatism

Country Status (23)

Country Link
US (7) US9579308B2 (enExample)
EP (3) EP4272743A3 (enExample)
JP (1) JP6141850B2 (enExample)
KR (1) KR102017916B1 (enExample)
CN (1) CN104093404B (enExample)
AU (2) AU2012311239B2 (enExample)
BR (1) BR112014006607A2 (enExample)
CA (2) CA3049795A1 (enExample)
CL (1) CL2014000689A1 (enExample)
CO (1) CO7000769A2 (enExample)
DK (1) DK2758047T3 (enExample)
ES (1) ES2715296T3 (enExample)
IL (1) IL231631B (enExample)
IN (1) IN2014CN02961A (enExample)
MX (1) MX357635B (enExample)
MY (1) MY168643A (enExample)
PH (1) PH12014500636B1 (enExample)
RU (1) RU2630968C2 (enExample)
SG (1) SG11201400828RA (enExample)
TR (1) TR201903465T4 (enExample)
UA (1) UA113525C2 (enExample)
WO (1) WO2013041967A2 (enExample)
ZA (1) ZA201402049B (enExample)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
US12478503B2 (en) 2009-05-18 2025-11-25 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
IN2014CN02961A (enExample) 2011-09-20 2015-07-03 Altavista Inst De Invest Medica S A S
TWI588560B (zh) 2012-04-05 2017-06-21 布萊恩荷登視覺協會 用於屈光不正之鏡片、裝置、方法及系統
US10507245B2 (en) 2012-07-19 2019-12-17 Luis Felipe Vejarano Restrepo Ophthalmic formulation and method for ameliorating presbyopia
US9201250B2 (en) 2012-10-17 2015-12-01 Brien Holden Vision Institute Lenses, devices, methods and systems for refractive error
CA2887655C (en) 2012-10-17 2021-11-02 Brien Holden Vision Institute Lenses, devices, methods and systems for refractive error
US10064818B2 (en) 2013-08-28 2018-09-04 Presbyopia Therapies, LLC Compositions and methods for the treatment of presbyopia
US9844537B2 (en) 2013-08-28 2017-12-19 Presbyopia Therapies Llc Compositions and methods for the treatment of presbyopia
US9320709B2 (en) 2013-08-28 2016-04-26 Presbyopia Therapies Llc Storage stable compositions and methods for the treatment of refractive errors of the eye
US9089562B2 (en) 2013-08-28 2015-07-28 Presbyopia Therapies Llc Compositions and methods for the treatment of presbyopia
US10617763B2 (en) 2013-08-28 2020-04-14 Presbyopia Therapies, LLC Compositions and methods for the treatment of presbyopia
US9314427B2 (en) 2013-08-28 2016-04-19 Presbyopia Therapies Llc Compositions and methods for the improvement of distance vision and the treatment of refractive errors of the eye
US9833441B2 (en) 2013-08-28 2017-12-05 Presbyopia Therapies Llc Compositions and methods for the treatment of presbyopia
US9968594B2 (en) 2013-08-28 2018-05-15 Presbyopia Therapies Llc Compositions and methods for the treatment of presbyopia
US10307408B2 (en) 2013-08-28 2019-06-04 Presbyopia Therapies, LLC Contact lens compositions and methods for the treatment of presbyopia
US11179327B2 (en) 2013-08-28 2021-11-23 Lenz Therapeutics, Inc. Compositions and methods for the treatment of presbyopia
ES2538551B1 (es) * 2013-12-20 2016-01-13 Eurocanarias Oftalmológica, Sl Composición Oftálmica para la corrección de la presbicia
EP3244851B1 (en) 2015-01-12 2024-10-16 Bausch + Lomb Ireland Limited Micro-droplet delivery device
CN104622800A (zh) * 2015-02-03 2015-05-20 吉林修正药业新药开发有限公司 苄达赖氨酸滴眼液及制备方法
KR20170135862A (ko) 2015-04-10 2017-12-08 켄달리온 테라퓨틱스 인코포레이티드 교체 가능한 앰플을 갖는 압전 디스펜서
CA2987787C (en) 2015-06-18 2023-06-27 Presbyopia Therapies, LLC Compositions for the improvement of distance vision and the treatment of refractive errors of the eye
US12653779B2 (en) 2015-06-18 2026-06-16 Lenz Therapeutics Operations, Inc. Compositions and methods for the treatment of presbyopia
US20190000808A1 (en) * 2015-07-13 2019-01-03 Allergan, Inc. Composition and methods for the treatment of blephopharoptosis
CH711969A2 (it) * 2015-12-29 2017-06-30 Pinelli Roberto Composizione per il trattamento della presbiopia.
KR102472774B1 (ko) * 2016-08-19 2022-11-30 오라시스 파마슈티칼스 엘티디. 안과용 약학 조성물 및 이와 관련된 용도
CN109906120A (zh) 2017-01-20 2019-06-18 科达莱昂治疗公司 压电流体分配器
WO2019113483A1 (en) 2017-12-08 2019-06-13 Kedalion Therapeutics, Inc. Fluid delivery alignment system
WO2019200121A1 (en) * 2018-04-12 2019-10-17 Kedalion Therapeutics, Inc. Topical ocular delivery methods and devices for use in the same
US12350194B1 (en) * 2018-04-12 2025-07-08 Bausch + Lomb Ireland Limited Topical ocular delivery of fluids with controlled mass dosing and wireless communication
JP6946575B2 (ja) 2018-04-24 2021-10-06 アラーガン、インコーポレイテッドAllergan,Incorporated 眼の状態の治療のためのピロカルピン塩酸塩の使用
EP3817696B8 (en) 2018-07-03 2024-12-11 Bausch + Lomb Ireland Limited Topical ocular delivery devices
US20210251970A1 (en) 2018-10-10 2021-08-19 Presbyopia Therapies Inc Compositions and methods for storage stable ophthalmic drugs
BR112021006618B1 (pt) 2018-10-10 2022-09-27 Presbyopia Therapies, Inc Composições e métodos para o tratamento da presbiopia
KR20210135269A (ko) * 2019-03-04 2021-11-12 아이노비아 인코포레이티드 필로카르핀을 눈에 액적의 마이크로-용량 스트림으로 전달하기 위한 방법 및 장치
US11679028B2 (en) 2019-03-06 2023-06-20 Novartis Ag Multi-dose ocular fluid delivery system
US12097145B2 (en) 2019-03-06 2024-09-24 Bausch + Lomb Ireland Limited Vented multi-dose ocular fluid delivery system
WO2020252061A1 (en) * 2019-06-10 2020-12-17 Visus Therapeutics, Inc. Carabachol-bromonidine formulation to enhance anti-presbyopia effects
EP3980017A4 (en) * 2019-06-10 2023-06-28 Visus Therapeutics, Inc. Using parasympathomimetic drugs alone or, in combination with one or more alpha agonists in pseudophakic patients, to create multi-focality
US12496218B1 (en) 2019-11-12 2025-12-16 Bausch + Lomb Ireland Limited Fractionated topical ocular drug delivery methods and devices for use in the same
CA3180199A1 (en) 2020-04-17 2021-10-21 Yehuda Ivri Hydrodynamically actuated preservative free dispensing system
US11938057B2 (en) 2020-04-17 2024-03-26 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
US12290472B2 (en) 2020-04-17 2025-05-06 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
EP4120973B1 (en) 2020-04-17 2026-06-10 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system having a collapsible liquid reservoir
BR112022026911A2 (pt) * 2020-09-11 2023-03-28 Intratus Nevada Inc Composições e métodos para tratar presbiopia, hipermetropia, astigmatismo, diminuição da estereopsia e diminuição da sensibilidade ao contraste
MX394625B (es) * 2020-11-12 2025-03-24 Cesar Alejandro Sanchez Galeana Composicion oftalmologica sinergica en dosis de baja concentracion eficaz en la prevencion, control y erradicacion de la presbicia
WO2022182740A1 (en) 2021-02-24 2022-09-01 Ocular Therapeutix, Inc. Intracanalicular depot inserter device
WO2023086878A1 (en) 2021-11-10 2023-05-19 Visus Therapeutics, Inc. Carbachol formulations to enhance anti-presbyopia effects
WO2023091439A1 (en) 2021-11-17 2023-05-25 Lenz Therapeutics, Inc. Aceclidine derivatives, compositions thereof and methods of use thereof
US11648247B1 (en) 2021-12-16 2023-05-16 Lenz Therapeutics, Inc. Compositions and methods for the treatment of presbyopia
US20250127760A1 (en) * 2021-12-28 2025-04-24 Shenyang Xingqi Pharmaceutical Co., Ltd. Composition and use thereof in preparation of medicament for treating presbyopia
US20230277521A1 (en) * 2022-03-07 2023-09-07 Harrow Ip, Llc Extended-release pharmaceutical compositions for treating eye conditions
WO2024220441A1 (en) * 2023-04-17 2024-10-24 Lenz Therapeutics Operations, Inc. Methods for the treatment of presbyopia
CN117414333A (zh) * 2023-11-30 2024-01-19 南京正科医药股份有限公司 盐酸毛果芸香碱滴眼液及其制备方法
US12414942B1 (en) 2024-03-15 2025-09-16 Lenz Therapeutics Operations, Inc. Compositions, methods, and systems for treating presbyopia

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3670087A (en) 1970-10-16 1972-06-13 Miles Lab Method of lowering intraocular pressure
US5122522A (en) 1989-06-21 1992-06-16 The Trustees Of The University Of Pennsylvania Treatment and control of ocular development
US5055467A (en) 1989-11-13 1991-10-08 Allergan, Inc. Pharmaceutical epinephrine-pilocarpine compounds
US5776916A (en) 1990-07-10 1998-07-07 Gramer; Eugen Medicament for reducing the intraocular pressure
US5459133A (en) 1992-06-05 1995-10-17 Telor Ophthalmic Pharmaceuticals, Inc. Methods and products for treating presbyopia
JPH07508751A (ja) 1992-07-02 1995-09-28 テラー・オフサルミック・ファーマシューティカルズ・インコーポレーテッド 老視治療のための方法および生産品
SE512871C2 (sv) 1992-08-20 2000-05-29 Santen Oy Oftalmologisk beredning innehållande pilokarpin och ytterligare medel för behandling av okular hypertension
US5422116A (en) 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
US6066675A (en) 1996-09-13 2000-05-23 The Regents Of The University Of California Method for treatment of retinal diseases
CN1175904C (zh) 1998-05-15 2004-11-17 若素制药株式会社 抗炎滴眼剂
US6291466B1 (en) 1998-07-30 2001-09-18 Allergan Sales, Inc. Cholinergic agents in the treatment of presbyopia
US6164282A (en) 1999-01-27 2000-12-26 Allergan Sales, Inc. Methods for restoring and/or enhancing accommodation in pseudo phakia
US6420407B1 (en) 1999-09-16 2002-07-16 Gerald Horn Ophthalmic formulation which modulates dilation
US6730065B1 (en) 2000-09-15 2004-05-04 Ocularis Pharma, Inc. Night vision composition
AU7581000A (en) 1999-09-16 2001-04-17 Gerald D. Horn A method for optimizing pupil size using alpha antagonist
WO2001037838A1 (en) 1999-11-24 2001-05-31 Wakamoto Pharmaceutical Co., Ltd. Ophthalmic aqueous preparation
US6730691B1 (en) 2000-02-10 2004-05-04 Miles A. Galin Uses of alpha adrenergic blocking agents
EP1299123A2 (en) * 2000-07-13 2003-04-09 Pharmacia Corporation Use of cox-2 inhibitors in the treatment and prevention of ocular cox-2 mediated disorders
PE20020146A1 (es) 2000-07-13 2002-03-31 Upjohn Co Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
US6273092B1 (en) 2000-09-22 2001-08-14 Gerard M. Nolan Methods for treating various eye disorders
US6515006B2 (en) 2000-11-08 2003-02-04 Hmt Pharma, Inc. Ophthalmic formulation which modulates dilation
US20050205101A1 (en) 2002-10-17 2005-09-22 Lin J T Combined pharmocological and surgical method and system for the treatment of eye disorders
US20040078009A1 (en) 2002-10-17 2004-04-22 Lin J. T. Method and apparatus for the treatment of presbyopia and other eye disorders combining pharmocological and surgical means
US20060177430A1 (en) 2002-12-20 2006-08-10 Chakshu Research Inc Treatment of ocular disorders with ophthalmic formulations containing methylsulfonylmethane as a transport enhancer
US20050119262A1 (en) 2003-08-21 2005-06-02 Pharmacia Corporation Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
MXPA03011987A (es) 2003-12-19 2005-06-23 Osio Sancho Alberto Metodo para el tratamiento de la presbicia induciendo cambios en el poder y fisiologia corneal.
WO2005099691A1 (en) * 2004-03-31 2005-10-27 Pharmacia & Upjohn Company Llc Composition for treating elevated intraocular pressure
ATE439863T1 (de) 2006-12-18 2009-09-15 Jorge Luis Benozzi Ophthalmische zusammensetzungen von parasympathischen stimulantia und entzündungshemmer zur verwendung bei der behandlung von presbyopie
GB0724558D0 (en) 2007-12-15 2008-01-30 Sharma Anant Optical correction
TNSN08110A1 (en) 2008-03-11 2009-07-14 Rekik Raouf Dr Drug delivery to the anterior and posterior segment of the eye from drops
CN102119120B (zh) * 2008-08-08 2013-08-07 株式会社东芝 纳米碳生成装置
CN102245166A (zh) * 2008-10-21 2011-11-16 法姆莱特有限公司 作为雾的含溴莫尼定的组合物的眼部施用
US20110091459A1 (en) 2008-12-11 2011-04-21 Auspex Pharmaceuticals, Inc. Imidazole modulators of muscarinic acetylcholine receptor m3
WO2010125416A1 (en) 2009-04-27 2010-11-04 Raouf Rekik Drug delivery to the anterior and posterior segments of the eye
US20100298335A1 (en) 2009-05-22 2010-11-25 Kaufman Herbert E Preparations and Methods for Ameliorating or Reducing Presbyopia
US8299079B2 (en) 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
JP2012015266A (ja) 2010-06-30 2012-01-19 Sony Corp 半導体光増幅器
AR081049A1 (es) 2010-08-17 2012-06-06 Gonzalez Santos Alejandro Raul Medicamento oftalmico para el tratamiento de la hipermetropia
TN2010000566A1 (en) 2010-12-03 2012-05-24 Rekik Raouf Folic acid - ramipril combination : cell protective neuroprotective and retinoprotective ophtalmologic drugs
CA2827373C (en) 2011-02-15 2019-05-14 Epi Health, Llc Pharmaceutical cream compositions of oxymetazoline for treating symptoms of rosacea
US20120225918A1 (en) 2011-03-03 2012-09-06 Voom, Llc Compositions and Methods for Non-Surgical Treatment of Ptosis
IN2014CN02961A (enExample) 2011-09-20 2015-07-03 Altavista Inst De Invest Medica S A S
WO2013061161A2 (en) 2011-10-28 2013-05-02 Green Bcn Consulting Services Sl New combination therapies for treating neurological disorders
US10507245B2 (en) 2012-07-19 2019-12-17 Luis Felipe Vejarano Restrepo Ophthalmic formulation and method for ameliorating presbyopia
US9089562B2 (en) 2013-08-28 2015-07-28 Presbyopia Therapies Llc Compositions and methods for the treatment of presbyopia
ES2538551B1 (es) 2013-12-20 2016-01-13 Eurocanarias Oftalmológica, Sl Composición Oftálmica para la corrección de la presbicia

Also Published As

Publication number Publication date
PH12014500636A1 (en) 2014-05-12
HK1198426A1 (en) 2015-04-24
CA2849366A1 (en) 2013-03-28
US20160310466A1 (en) 2016-10-27
US9579308B2 (en) 2017-02-28
AU2017239563B2 (en) 2019-09-26
NZ623037A (en) 2016-07-29
WO2013041967A3 (en) 2013-08-01
US20200069651A1 (en) 2020-03-05
US20140113946A1 (en) 2014-04-24
EP3517111A3 (en) 2019-12-11
RU2014115439A (ru) 2015-10-27
US20250049761A1 (en) 2025-02-13
AU2012311239B2 (en) 2017-10-19
MY168643A (en) 2018-11-27
IL231631B (en) 2019-07-31
EP2758047B1 (en) 2018-12-19
WO2013041967A2 (en) 2013-03-28
BR112014006607A2 (pt) 2017-04-25
EP3517111A2 (en) 2019-07-31
US20220040152A1 (en) 2022-02-10
EP2758047A2 (en) 2014-07-30
ZA201402049B (en) 2015-11-25
EP4272743A2 (en) 2023-11-08
US20180333392A1 (en) 2018-11-22
KR102017916B1 (ko) 2019-09-03
AU2012311239A1 (en) 2014-04-10
UA113525C2 (xx) 2017-02-10
PH12014500636B1 (en) 2019-11-20
TR201903465T4 (tr) 2019-04-22
WO2013041967A9 (en) 2013-06-13
US20140200211A1 (en) 2014-07-17
KR20140076587A (ko) 2014-06-20
IN2014CN02961A (enExample) 2015-07-03
MX357635B (es) 2018-07-17
CN104093404A (zh) 2014-10-08
CN104093404B (zh) 2016-12-07
CL2014000689A1 (es) 2015-01-09
JP6141850B2 (ja) 2017-06-07
AU2017239563A1 (en) 2017-10-26
JP2014533238A (ja) 2014-12-11
ES2715296T3 (es) 2019-06-03
RU2630968C2 (ru) 2017-09-15
US9301933B2 (en) 2016-04-05
CA2849366C (en) 2019-09-10
CA3049795A1 (en) 2013-03-28
DK2758047T3 (en) 2019-04-01
IL231631A0 (en) 2014-05-28
CO7000769A2 (es) 2014-07-21
MX2014003421A (es) 2014-10-17
EP4272743A3 (en) 2024-07-10

Similar Documents

Publication Publication Date Title
ZA201402049B (en) Compositions and methods for treating presbyopia, mild hyperopia, and irregular astigmatism
IL229257A0 (en) Compositions and methods for treating retinal diseases
EP2817018A4 (en) METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS
WO2012149472A9 (en) Methods, compositions, and kits for treating and preventing neurological conditions
PL2874660T3 (pl) Preparat okulistyczny i sposób łagodzenia starczowzroczności
PL2672966T3 (pl) Kompozycja farmaceutyczna, sposoby leczenia i jej zastosowania
PH12013500577A1 (en) Compositions and methods for treating ocular edema, neovascularization and related diseases
IL260714B (en) Methods for the treatment and diagnosis of blinding eye diseases
ZA201305783B (en) Composition and methods for treating cardiovascular diseases
IL232710A0 (en) l-serine preparations, methods and uses for the treatment of neurodegenerative diseases and disorders
EP2760359A4 (en) METHOD FOR TREATING EYE STATES
EP2663271A1 (en) Apparatus and methods for treating excess intraocular fluid
EP2753275A4 (en) METHODS OF TREATING OCULAR CONDITIONS
EP2770992A4 (en) AGENTS, METHODS AND DEVICES FOR AFFECTING NERVOUS FUNCTION
IL238416A0 (en) Preparations and methods for the treatment of diseases caused by protein pathology
EP2663653A2 (en) Methods for diagnosing and treating eye-length related disorders
PL2667877T3 (pl) Kompozycja androgenu do leczenia stanu okulistycznego
ZA201502600B (en) Combination of laquinimod and pridopidine for treating neurodegenerative disorders, in particular huntington's disease
DK3292875T3 (en) Compositions and methods for treating diseases
ZA201404187B (en) Compositions and methods for treating dental conditions
EP2558104A4 (en) METHOD AND OPHTHALMIC COMPOSITION FOR TREATING RETINAL DISEASE
WO2013022740A3 (en) Gpr35 ligands and the uses thereof
IL232648A0 (en) Preparations and methods for treating glioma
EP2663326A1 (en) Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
AP2013007056A0 (en) Methods and compositions for treating kidney disorders