SG108208A1 - Connective tissue growth factor - Google Patents

Connective tissue growth factor

Info

Publication number
SG108208A1
SG108208A1 SG9806251A SG1998006251A SG108208A1 SG 108208 A1 SG108208 A1 SG 108208A1 SG 9806251 A SG9806251 A SG 9806251A SG 1998006251 A SG1998006251 A SG 1998006251A SG 108208 A1 SG108208 A1 SG 108208A1
Authority
SG
Singapore
Prior art keywords
ctgf
growth factor
connective tissue
tissue growth
provides
Prior art date
Application number
SG9806251A
Other languages
English (en)
Inventor
R Grotendorst Gary
M Bradham Douglass Jr
Original Assignee
Univ South Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ South Florida filed Critical Univ South Florida
Publication of SG108208A1 publication Critical patent/SG108208A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655—Chondrocytes; Cartilage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
SG9806251A 1995-06-02 1996-05-31 Connective tissue growth factor SG108208A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/459,717 US5770209A (en) 1991-08-30 1995-06-02 Acceleration of wound healing using connective tissue growth factor

Publications (1)

Publication Number Publication Date
SG108208A1 true SG108208A1 (en) 2005-01-28

Family

ID=23825885

Family Applications (1)

Application Number Title Priority Date Filing Date
SG9806251A SG108208A1 (en) 1995-06-02 1996-05-31 Connective tissue growth factor

Country Status (11)

Country Link
US (4) US5770209A (ja)
EP (2) EP0831903B1 (ja)
JP (4) JPH11506449A (ja)
CN (2) CN1191491A (ja)
AT (1) ATE464067T1 (ja)
AU (2) AU720268B2 (ja)
BR (2) BR9608558A (ja)
CA (2) CA2222609A1 (ja)
DE (1) DE69638162D1 (ja)
SG (1) SG108208A1 (ja)
WO (2) WO1996038168A1 (ja)

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US6638912B2 (en) * 1995-05-01 2003-10-28 The Regents Of The University Of California Peptide compositions mimicking TGF-β activity
AU763649B2 (en) * 1995-06-02 2003-07-31 University Of South Florida Connective tissue growth factor
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US7521540B2 (en) * 1996-03-15 2009-04-21 Munin Corporation CYR61 compositions and methods
US20090081228A1 (en) * 1996-03-15 2009-03-26 Munin Corporation Cyr61 compositions and methods
US6790606B1 (en) * 1996-03-15 2004-09-14 Munin Corporation Extracellular matrix signaling molecules
US20040132987A1 (en) 1996-11-08 2004-07-08 Human Genome Sciences, Inc. Connective tissue growth factor-3
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CA2274122C (en) * 1996-12-06 2004-02-17 Osiris Therapeutics, Inc. Improved chondrogenic differentiation of human mesenchymal stem cells
DE19719652A1 (de) * 1997-05-09 1998-12-03 Merckle Gmbh Tissue-Faktor zur Förderung von Wundheilung
EP1003770A4 (en) * 1997-06-19 2002-10-30 Inst Genetics Llc SECRETIED POLYPEPTIDES AND THESE ENCODING POLYNUCLEOTIDES
AU7980598A (en) * 1997-06-19 1999-01-04 Incyte Pharmaceuticals, Inc. Polynucleotides encoding a growth factor-like protein (as amended)
US5876730A (en) * 1997-08-07 1999-03-02 Childrens Hospital Research Foundation Heparin-binding growth factor (HBGF) polypeptides
JP4537507B2 (ja) * 1997-12-25 2010-09-01 アムジェン インコーポレイテッド 結合組織増殖因子に対するモノクローナル抗体及びその医薬用途
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US20070141181A1 (en) 1998-02-13 2007-06-21 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
US6797289B2 (en) 1998-02-13 2004-09-28 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
US6451771B1 (en) 1999-02-12 2002-09-17 Nutramax Laboratories, Inc. Use of anabolic agents anti-catabolic agents and antioxidant agents for protection treatment and repair of connective tissues in humans and animals
CN1326361A (zh) 1998-09-08 2001-12-12 亨利福特保健系统公司 通过修饰、调节及抑制结缔组织生长因子来检查、预防和治疗肾脏疾病的方法
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US6555322B1 (en) 1999-08-27 2003-04-29 Fibrogen, Inc. α2-macroglobulin receptor as a receptor for CTGF
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US6939540B1 (en) 2000-07-31 2005-09-06 Cornell Research Foundation, Inc. Method of enhancing bone density
US6599526B2 (en) * 2000-08-18 2003-07-29 The University Of North Texas Health Science Center At Fort Worth Pericardial anti-adhesion patch
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US6965025B2 (en) * 2001-12-10 2005-11-15 Isis Pharmaceuticals, Inc. Antisense modulation of connective tissue growth factor expression
CN1602427A (zh) * 2001-12-12 2005-03-30 默克专利股份公司 三重四脯氨酸碱性蛋白用于保护心脏避免发生心脏损伤的抑制作用
JP2005523928A (ja) * 2002-04-30 2005-08-11 アルコン，インコーポレイテッド 眼内圧の低下および緑内障性網膜症／眼神経障害の処置の両方のための独特の手段としての、結合組織増殖因子（ｃｔｇｆ）の活性および／または発現を調節するか、阻害するか、または調整する薬剤
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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5408040A (en) * 1991-08-30 1995-04-18 University Of South Florida Connective tissue growth factor(CTGF)

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US5149691A (en) * 1991-03-12 1992-09-22 Creative Biomolecules, Inc. Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone
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Also Published As

Publication number Publication date
CA2222509C (en) 2012-12-04
CA2222509A1 (en) 1996-12-05
DE69638162D1 (de) 2010-05-27
JP2007051150A (ja) 2007-03-01
AU722919B2 (en) 2000-08-17
AU720268B2 (en) 2000-05-25
JPH11506449A (ja) 1999-06-08
JPH11507332A (ja) 1999-06-29
JP2004132974A (ja) 2004-04-30
US5770209A (en) 1998-06-23
WO1996038168A1 (en) 1996-12-05
US6150101A (en) 2000-11-21
CA2222609A1 (en) 1996-12-05
AU5958296A (en) 1996-12-18
EP0831903A1 (en) 1998-04-01
EP0831885A1 (en) 1998-04-01
EP0831885A4 (en) 2000-11-29
MX9709294A (es) 1998-08-30
WO1996038172A1 (en) 1996-12-05
CN1195295A (zh) 1998-10-07
BR9609521A (pt) 1999-06-15
EP0831903B1 (en) 2010-04-14
EP0831903A4 (en) 2001-02-28
BR9608558A (pt) 1999-11-30
CN1191491A (zh) 1998-08-26
US6232064B1 (en) 2001-05-15
US6069006A (en) 2000-05-30
AU5885596A (en) 1996-12-18
ATE464067T1 (de) 2010-04-15

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