SG10202111841TA - Nanopore-based analysis of protein characteristics - Google Patents

Nanopore-based analysis of protein characteristics

Info

Publication number
SG10202111841TA
SG10202111841TA SG10202111841TA SG10202111841TA SG10202111841TA SG 10202111841T A SG10202111841T A SG 10202111841TA SG 10202111841T A SG10202111841T A SG 10202111841TA SG 10202111841T A SG10202111841T A SG 10202111841TA SG 10202111841T A SG10202111841T A SG 10202111841TA
Authority
SG
Singapore
Prior art keywords
nanopore
based analysis
protein characteristics
protein
analysis
Prior art date
Application number
SG10202111841TA
Other languages
English (en)
Inventor
Jens Gundlach
Ian Derrington
Andrew Laszlo
Jonathan Craig
Henry Brinkerhoff
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Publication of SG10202111841TA publication Critical patent/SG10202111841TA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44743—Introducing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818—Sequencing of polypeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nanotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
SG10202111841TA 2014-02-19 2014-11-26 Nanopore-based analysis of protein characteristics SG10202111841TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461941919P 2014-02-19 2014-02-19

Publications (1)

Publication Number Publication Date
SG10202111841TA true SG10202111841TA (en) 2021-12-30

Family

ID=53878776

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201607796TA SG11201607796TA (en) 2014-02-19 2014-11-26 Nanopore-based analysis of protein characteristics
SG10202111841TA SG10202111841TA (en) 2014-02-19 2014-11-26 Nanopore-based analysis of protein characteristics

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201607796TA SG11201607796TA (en) 2014-02-19 2014-11-26 Nanopore-based analysis of protein characteristics

Country Status (5)

Country Link
US (4) US10359395B2 (fr)
EP (1) EP3108229A4 (fr)
CN (1) CN106133513B (fr)
SG (2) SG11201607796TA (fr)
WO (1) WO2015126494A1 (fr)

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EP3646025B1 (fr) * 2017-06-29 2021-08-04 President and Fellows of Harvard College Progression déterministe de polymères à travers un nanopore
CN107942070B (zh) * 2017-11-16 2020-12-01 苏州市东挺河智能科技发展有限公司 一种用于血液巡航的纳米生物监测器及其应急信息ar显示
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CN109270154A (zh) * 2018-10-29 2019-01-25 东南大学 基于dna四面体的固态纳米孔单分子蛋白质检测信号放大方法及dna四面体
CN111499705B (zh) * 2019-01-30 2023-08-08 深圳市梅丽纳米孔科技有限公司 一种突变NfpAB纳米孔、测试系统及制作方法与应用
WO2020168286A1 (fr) * 2019-02-14 2020-08-20 University Of Washington Systèmes et procédés pour analyse fondée sur des nanopores d'acides nucléiques améliorée
CN112147185B (zh) * 2019-06-29 2022-07-01 清华大学 一种控制多肽穿过纳米孔速度的方法及其应用
CN110729915B (zh) * 2019-11-20 2022-04-19 西南大学 一种水超分子马达的制备方法
NL2024579B1 (en) 2019-12-24 2021-09-06 Univ Delft Tech Protein and peptide fingerprinting and sequencing by nanopore translocation of peptide-oligonucleotide complexes
CN112578106B (zh) * 2020-04-13 2022-04-22 南京大学 一种纳米孔道单分子蛋白质测序仪
WO2021208936A1 (fr) * 2020-04-14 2021-10-21 成都今是科技有限公司 Procédé de préparation et de détection de nanopores et appareil de détection correspondant
CN111413383B (zh) * 2020-04-20 2021-03-02 深圳市梅丽纳米孔科技有限公司 一种构建双识别位点纳米孔的方法
CN115219558A (zh) * 2021-04-15 2022-10-21 苏州罗岛纳米科技有限公司 一种蛋白分子与dna结合位置定位方法及设备
EP4352499A1 (fr) * 2021-05-13 2024-04-17 Nanjing University Profilage structural d'analytes par piégeage de nanopores
CN113322180B (zh) * 2021-05-31 2022-07-15 中国科学院物理研究所 基于纳米孔测序的力谱分析方法和分析装置
CN116165373A (zh) * 2021-08-30 2023-05-26 四川大学 一种基于铜离子修饰MspA纳米孔的多肽成分分析方法
CN114199971B (zh) * 2021-12-16 2024-03-22 中国科学院重庆绿色智能技术研究院 基于化学修饰的纳米孔对整合素构象检测的方法
CN115877018A (zh) * 2022-08-05 2023-03-31 四川大学华西医院 一种孔蛋白在制备检测去氢表雄酮硫酸酯的试剂盒中的应用

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Also Published As

Publication number Publication date
US11808734B2 (en) 2023-11-07
US20170199149A1 (en) 2017-07-13
EP3108229A1 (fr) 2016-12-28
WO2015126494A1 (fr) 2015-08-27
US20210293748A1 (en) 2021-09-23
SG11201607796TA (en) 2016-11-29
US10359395B2 (en) 2019-07-23
US10948454B2 (en) 2021-03-16
CN106133513A (zh) 2016-11-16
CN106133513B (zh) 2019-08-13
US20240085372A1 (en) 2024-03-14
US20200049656A1 (en) 2020-02-13
EP3108229A4 (fr) 2017-09-06

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