SG11201607796TA - Nanopore-based analysis of protein characteristics - Google Patents

Nanopore-based analysis of protein characteristics

Info

Publication number
SG11201607796TA
SG11201607796TA SG11201607796TA SG11201607796TA SG11201607796TA SG 11201607796T A SG11201607796T A SG 11201607796TA SG 11201607796T A SG11201607796T A SG 11201607796TA SG 11201607796T A SG11201607796T A SG 11201607796TA SG 11201607796T A SG11201607796T A SG 11201607796TA
Authority
SG
Singapore
Prior art keywords
nanopore
based analysis
protein characteristics
protein
analysis
Prior art date
Application number
SG11201607796TA
Inventor
Jens Gundlach
Ian Michael Derrington
Andrew Laszlo
Jonathan Craig
Henry Brinkerhoff
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Publication of SG11201607796TA publication Critical patent/SG11201607796TA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44743—Introducing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818—Sequencing of polypeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nanotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
SG11201607796TA 2014-02-19 2014-11-26 Nanopore-based analysis of protein characteristics SG11201607796TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461941919P 2014-02-19 2014-02-19
PCT/US2014/067732 WO2015126494A1 (en) 2014-02-19 2014-11-26 Nanopore-based analysis of protein characteristics

Publications (1)

Publication Number Publication Date
SG11201607796TA true SG11201607796TA (en) 2016-11-29

Family

ID=53878776

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201607796TA SG11201607796TA (en) 2014-02-19 2014-11-26 Nanopore-based analysis of protein characteristics
SG10202111841TA SG10202111841TA (en) 2014-02-19 2014-11-26 Nanopore-based analysis of protein characteristics

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10202111841TA SG10202111841TA (en) 2014-02-19 2014-11-26 Nanopore-based analysis of protein characteristics

Country Status (5)

Country Link
US (4) US10359395B2 (en)
EP (1) EP3108229A4 (en)
CN (1) CN106133513B (en)
SG (2) SG11201607796TA (en)
WO (1) WO2015126494A1 (en)

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EP3646025B1 (en) * 2017-06-29 2021-08-04 President and Fellows of Harvard College Deterministic stepping of polymers through a nanopore
CN111665349A (en) * 2017-11-16 2020-09-15 李敏 Nanometer biological monitor for blood cruising
CN112423878B (en) * 2018-02-12 2024-06-18 牛津纳米孔科技公开有限公司 Nanopore assembly and uses thereof
JP2020031557A (en) * 2018-08-28 2020-03-05 株式会社日立ハイテクノロジーズ Biomolecule analyzer
CN109270154A (en) * 2018-10-29 2019-01-25 东南大学 Based on the tetrahedral solid nano hole unimolecule protein detection method for amplifying signal of DNA and DNA tetrahedron
CN111499705B (en) * 2019-01-30 2023-08-08 深圳市梅丽纳米孔科技有限公司 Mutant NfpAB nanopore, testing system, manufacturing method and application
US20220366313A1 (en) * 2019-02-14 2022-11-17 University Of Washington Systems and methods for improved nanopore-based analysis of nucleic acids
CN112147185B (en) * 2019-06-29 2022-07-01 清华大学 Method for controlling speed of polypeptide passing through nanopore and application of method
CN110729915B (en) * 2019-11-20 2022-04-19 西南大学 Preparation method of water supermolecule motor
NL2024579B1 (en) 2019-12-24 2021-09-06 Univ Delft Tech Protein and peptide fingerprinting and sequencing by nanopore translocation of peptide-oligonucleotide complexes
CN112578106B (en) * 2020-04-13 2022-04-22 南京大学 Nano-pore single-molecule protein sequencer
WO2021208936A1 (en) * 2020-04-14 2021-10-21 成都今是科技有限公司 Nanopore preparation and detection method and detection apparatus thereof
CN111413383B (en) * 2020-04-20 2021-03-02 深圳市梅丽纳米孔科技有限公司 Method for constructing double-recognition-site nanopore
CN115219558A (en) * 2021-04-15 2022-10-21 苏州罗岛纳米科技有限公司 Method and equipment for positioning combination position of protein molecule and DNA
WO2022237883A1 (en) * 2021-05-13 2022-11-17 Nanjing University Structural-profiling of analytes by nanopore trapping
CN113322180B (en) * 2021-05-31 2022-07-15 中国科学院物理研究所 Force spectrum analysis method and analysis device based on nanopore sequencing
CN116165373A (en) * 2021-08-30 2023-05-26 四川大学 Polypeptide component analysis method based on copper ion modified MspA nanopore
CN114199971B (en) * 2021-12-16 2024-03-22 中国科学院重庆绿色智能技术研究院 Method for detecting conformation of integrin based on chemically modified nano-pore
CN115877018A (en) * 2022-08-05 2023-03-31 四川大学华西医院 Application of porin in preparation of kit for detecting dehydroepiandrosterone sulfate

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Also Published As

Publication number Publication date
CN106133513B (en) 2019-08-13
EP3108229A1 (en) 2016-12-28
US11808734B2 (en) 2023-11-07
WO2015126494A1 (en) 2015-08-27
CN106133513A (en) 2016-11-16
US20240085372A1 (en) 2024-03-14
SG10202111841TA (en) 2021-12-30
US20210293748A1 (en) 2021-09-23
US20170199149A1 (en) 2017-07-13
US10359395B2 (en) 2019-07-23
US20200049656A1 (en) 2020-02-13
US10948454B2 (en) 2021-03-16
EP3108229A4 (en) 2017-09-06

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