SG10202008679RA - Apparatus for subretinal administration of therapeutic agent via a curved needle - Google Patents

Apparatus for subretinal administration of therapeutic agent via a curved needle

Info

Publication number
SG10202008679RA
SG10202008679RA SG10202008679RA SG10202008679RA SG10202008679RA SG 10202008679R A SG10202008679R A SG 10202008679RA SG 10202008679R A SG10202008679R A SG 10202008679RA SG 10202008679R A SG10202008679R A SG 10202008679RA SG 10202008679R A SG10202008679R A SG 10202008679RA
Authority
SG
Singapore
Prior art keywords
therapeutic agent
agent via
curved needle
subretinal administration
subretinal
Prior art date
Application number
SG10202008679RA
Other languages
English (en)
Inventor
Thomas E Meyer
Benjamin L Ko
Isaac J Khan
Daniel W Price
Brendan J Oberkircher
Michael F Keane
Original Assignee
Gyroscope Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyroscope Therapeutics Ltd filed Critical Gyroscope Therapeutics Ltd
Publication of SG10202008679RA publication Critical patent/SG10202008679RA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/008—Methods or devices for eye surgery using laser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/008—Strength or flexibility characteristics of the catheter tip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0082—Catheter tip comprising a tool
    • A61M25/0084—Catheter tip comprising a tool being one or more injection needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0113—Mechanical advancing means, e.g. catheter dispensers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
    • A61M5/3291—Shafts with additional lateral openings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1585—Needle inserters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/587—Lighting arrangements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0612—Eyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
SG10202008679RA 2016-03-09 2017-03-09 Apparatus for subretinal administration of therapeutic agent via a curved needle SG10202008679RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662305767P 2016-03-09 2016-03-09
US15/438,918 US10478553B2 (en) 2016-03-09 2017-02-22 Apparatus for subretinal administration of therapeutic agent via a curved needle

Publications (1)

Publication Number Publication Date
SG10202008679RA true SG10202008679RA (en) 2020-10-29

Family

ID=59788385

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202008679RA SG10202008679RA (en) 2016-03-09 2017-03-09 Apparatus for subretinal administration of therapeutic agent via a curved needle
SG11201807191YA SG11201807191YA (en) 2016-03-09 2017-03-09 Apparatus for subretinal administration of therapeutic agent via a curved needle

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201807191YA SG11201807191YA (en) 2016-03-09 2017-03-09 Apparatus for subretinal administration of therapeutic agent via a curved needle

Country Status (14)

Country Link
US (3) US10478553B2 (enExample)
EP (1) EP3426203B1 (enExample)
JP (3) JP7023873B2 (enExample)
KR (3) KR102608333B1 (enExample)
CN (2) CN113616417B (enExample)
AU (1) AU2017229763B2 (enExample)
BR (1) BR112018067896A2 (enExample)
CA (2) CA3175975A1 (enExample)
ES (1) ES3031816T3 (enExample)
IL (1) IL261251B (enExample)
RU (1) RU2740165C2 (enExample)
SA (1) SA518392352B1 (enExample)
SG (2) SG10202008679RA (enExample)
WO (1) WO2017156227A1 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10478553B2 (en) * 2016-03-09 2019-11-19 Orbit Biomedical Limited Apparatus for subretinal administration of therapeutic agent via a curved needle
US10646374B2 (en) 2016-06-17 2020-05-12 Orbit Biomedical Limited Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent
US10806629B2 (en) 2016-06-17 2020-10-20 Gyroscope Therapeutics Limited Injection device for subretinal delivery of therapeutic agent
US11076984B2 (en) 2017-03-13 2021-08-03 Gyroscope Therapeutics Limited Method of performing subretinal drainage and agent delivery
US11033427B2 (en) 2017-04-13 2021-06-15 Alcon Inc. Vitreoretinal instruments for fluid aspiration
GB201714392D0 (en) 2017-09-07 2017-10-25 Marsteller Laurence Methods and devices for treating glaucoma
US11666780B2 (en) * 2017-09-07 2023-06-06 Radiance Therapeutics, Inc. Methods, systems, and compositions for maintaining functioning drainage blebs associated with minimally invasive micro sclerostomy
US10960147B2 (en) * 2018-04-20 2021-03-30 Flextronics Ap, Llc Flex needle
EP3829501B1 (en) * 2018-08-03 2025-12-31 The Johns Hopkins University RETINAL IMPLANTATION DEVICE
US20220125633A1 (en) * 2019-02-06 2022-04-28 The Johns Hopkins University External and internal intraoperative optical coherence tomography imaging for subretinal material delivery
US11759355B1 (en) 2019-02-26 2023-09-19 Gyroscope Therapeutics Limited Method of delivering leading blebs and agent to subretinal space
CN114555016B (zh) 2019-10-11 2024-10-01 陀螺仪治疗学有限公司 用于注射器的剂量夹组件
WO2022136913A1 (en) 2020-12-22 2022-06-30 Gyroscope Therapeutics Limited Ocular cannula guide
USD1076086S1 (en) 2021-11-23 2025-05-20 Radiance Therapeutics, Inc. Opthalmic brachytherapy device
USD1076085S1 (en) 2021-11-23 2025-05-20 Radiance Therapeutics, Inc. Opthalmic brachytherapy device
IL319330A (en) 2022-09-06 2025-05-01 Genentech Inc A device for subretinal administration of a therapeutic agent using a double curved needle
IL322034A (en) 2023-01-13 2025-09-01 Genentech Inc Syringe dosing station
WO2024249805A1 (en) * 2023-05-31 2024-12-05 The Johns Hopkins University Methods and systems for accessing anatomical spaces
US20240423836A1 (en) * 2023-06-22 2024-12-26 Alcon Inc. Methods and apparatus for subretinal delivery
AU2024314616A1 (en) * 2023-06-22 2025-11-13 Alcon Inc. Methods and apparatus for subretinal delivery
US20240423833A1 (en) * 2023-06-22 2024-12-26 Alcon Inc. Methods and apparatus for subretinal delivery
TW202529711A (zh) 2023-09-29 2025-08-01 美商建南德克公司 眼插管導引器、施用器及標記器械
WO2025207699A1 (en) 2024-03-27 2025-10-02 Genentech, Inc. Torque ring for subretinal injection device
WO2025217214A2 (en) 2024-04-08 2025-10-16 Regenxbio Inc. Recombinant adeno-associated viruses and uses thereof
WO2025217230A1 (en) 2024-04-08 2025-10-16 Regenxbio Inc. Vectorized anti-complement antibodies and complement agents and administration thereof

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5273530A (en) 1990-11-14 1993-12-28 The University Of Rochester Intraretinal delivery and withdrawal instruments
DE4235506A1 (de) * 1992-10-21 1994-04-28 Bavaria Med Tech Katheter zur Injektion von Arzneimitteln
US5964740A (en) * 1996-07-09 1999-10-12 Asahi Kogaku Kogyo Kabushiki Kaisha Treatment accessory for an endoscope
CN1204242A (zh) * 1995-10-13 1999-01-06 血管转换公司 为动脉阻塞物加设旁路和/或其他经血管操作的方法和装置
ATE275880T1 (de) * 1995-10-13 2004-10-15 Transvascular Inc Vorrichtung zur umgehung von arteriellen verengungen und/oder zur ausführung anderer transvaskularer eingriffe
DE19741487C2 (de) 1997-09-19 2000-08-31 Univ Eberhard Karls Vorrichtung für einen Zugang in den Subretinalraum eines Auges
US6231546B1 (en) * 1998-01-13 2001-05-15 Lumend, Inc. Methods and apparatus for crossing total occlusions in blood vessels
JP3055504U (ja) * 1998-07-02 1999-01-22 株式会社八光電機製作所 眼球針
US6217554B1 (en) * 1999-02-12 2001-04-17 Pharmaspec Corporation Methods and apparatus for delivering substances into extravascular tissue
US6368315B1 (en) 1999-06-23 2002-04-09 Durect Corporation Composite drug delivery catheter
DE60018777T2 (de) * 1999-10-21 2006-02-02 Alcon Inc. Medikamentenversorgung der sub-tenon
US7357794B2 (en) * 2002-01-17 2008-04-15 Medtronic Vascular, Inc. Devices, systems and methods for acute or chronic delivery of substances or apparatus to extravascular treatment sites
US6989004B2 (en) * 2001-02-28 2006-01-24 Rex Medical, L.P. Apparatus for delivering ablation fluid to treat lesions
AU2003213075A1 (en) 2002-02-14 2003-09-04 Henry J. Kaplan Subretinal implantation device and surgical cannulas for use therewith
US7316676B2 (en) * 2002-08-20 2008-01-08 Gholam A. Peyman Treatment of retinal detachment
WO2004028477A2 (en) 2002-09-29 2004-04-08 Surmodics, Inc. Methods for treatment and/or prevention of retinal disease
US20040199130A1 (en) * 2003-04-03 2004-10-07 Chornenky Victor I. Apparatus and method for treatment of macular degeneration
JP4289919B2 (ja) * 2003-05-06 2009-07-01 朝日インテック株式会社 薬液注入装置
IL156582A0 (en) * 2003-06-22 2004-01-04 Sergey Popov Safety trocar obturator
PL1641916T3 (pl) 2003-06-27 2016-08-31 Depuy Synthes Products Inc Regeneracja i naprawa tkanki nerwowej z wykorzystaniem komórek poporodowych
GB0327136D0 (en) * 2003-11-21 2003-12-24 Nmt Group Plc Safety needle
PL1715827T3 (pl) 2004-01-23 2011-07-29 Iscience Interventional Corp Złożona okulistyczna mikrokaniula
CA2564840A1 (en) * 2004-04-29 2005-11-17 Michael Hee Apparatus and method for ocular treatment
US20080058704A1 (en) 2004-04-29 2008-03-06 Michael Hee Apparatus and Method for Ocular Treatment
WO2007002304A2 (en) * 2005-06-22 2007-01-04 Vnus Medical Technologies, Inc. Methods and apparatus for introducing tumescent fluid to body tissue
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US20080004596A1 (en) * 2006-05-25 2008-01-03 Palo Alto Institute Delivery of agents by microneedle catheter
JP2010504151A (ja) * 2006-09-19 2010-02-12 ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク 中空の解剖学的に懸吊された器官の手術のためのシステム、装置、及び方法
US20080281292A1 (en) 2006-10-16 2008-11-13 Hickingbotham Dyson W Retractable Injection Port
US8002743B2 (en) * 2007-06-15 2011-08-23 Kyphon Sarl Systems and methods for needle access to an intervertebral disc
EP2227257B1 (en) * 2008-01-07 2013-06-26 Salutaris Medical Devices, Inc. Devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye
WO2009089409A2 (en) 2008-01-10 2009-07-16 Bausch & Lomb Incorporated Intravitreal injection system having coaxial cannulae and use thereof
US8021332B2 (en) * 2008-12-04 2011-09-20 Abbott Cardiovascular Systems Inc. Agent delivery catheter having articulating arms
US8425473B2 (en) 2009-01-23 2013-04-23 Iscience Interventional Corporation Subretinal access device
EP2429607A4 (en) * 2009-05-15 2014-01-08 Iscience Interventional Corp METHOD AND DEVICE FOR SUBRETINAL CATHETERIZATION
EP2437841B1 (en) * 2009-06-05 2019-10-30 Cook Medical Technologies LLC Access sheath and needle assembly for delivering therapeutic material
US20120271272A1 (en) 2010-10-15 2012-10-25 Iscience Interventional Corporation Device for ocular access
GB2487899A (en) * 2011-02-01 2012-08-15 Olberon Ltd Needle holder with grip means
JP5717182B2 (ja) * 2011-02-25 2015-05-13 Hoya株式会社 眼科手術器具
US8852165B2 (en) * 2011-06-16 2014-10-07 II Edward G. Mackay Endoluminal drug delivery devices and methods
US9414816B2 (en) * 2011-06-23 2016-08-16 Devicor Medical Products, Inc. Introducer for biopsy device
US8938285B2 (en) * 2011-08-08 2015-01-20 Devicor Medical Products, Inc. Access chamber and markers for biopsy device
US9370447B2 (en) * 2011-10-10 2016-06-21 Cygnus LP Probes for use in ophthalmic and vitreoretinal surgery
US9629675B2 (en) * 2011-10-19 2017-04-25 Confluent Medical Technologies, Inc. Tissue treatment device and related methods
ES2533576T3 (es) * 2011-12-30 2015-04-13 Q-Med Ab Cánula sin hematomas
WO2013123309A1 (en) * 2012-02-15 2013-08-22 The Cleveland Clinic Foundation Catheter assembly and method of treating a vascular disease
WO2014036009A1 (en) 2012-08-27 2014-03-06 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using microneedles
US9301795B2 (en) * 2012-10-29 2016-04-05 Ablative Solutions, Inc. Transvascular catheter for extravascular delivery
CN110893188A (zh) 2012-11-08 2020-03-20 克莱尔塞德生物医学股份有限公司 用于在人类受试者中治疗眼部疾病的方法和装置
EP3068354B1 (en) * 2013-11-14 2023-06-28 Aquesys, Inc. Intraocular shunt inserter
US10010447B2 (en) * 2013-12-18 2018-07-03 Novartis Ag Systems and methods for subretinal delivery of therapeutic agents
JP5777074B2 (ja) * 2013-12-24 2015-09-09 公立大学法人横浜市立大学 注射針
CN110680606B (zh) * 2014-02-12 2023-07-21 陀螺仪治疗学有限公司 用于治疗剂的脉络膜上施用的方法和设备
US9925088B2 (en) 2014-06-06 2018-03-27 Janssen Biotech, Inc. Sub-retinal tangential needle catheter guide and introducer
US9949874B2 (en) 2014-06-06 2018-04-24 Janssen Biotech, Inc. Therapeutic agent delivery device with convergent lumen
KR102511477B1 (ko) 2014-06-17 2023-03-16 클리어사이드 바이오메디컬, 인코포레이드 안구 후부 질환을 치료하기 위한 방법 및 디바이스
RU2710491C2 (ru) 2014-06-20 2019-12-26 Клиасайд Байомедикал, Инк. Устройство для инъекции лекарственного средства в глазную ткань и способ инъекции лекарственного средства в глазную ткань
US9949875B1 (en) * 2014-07-08 2018-04-24 Jeffrey N. Weiss Retinal and optic nerve autologous bone-marrow derived stem cell surgery
US10456557B2 (en) * 2014-08-14 2019-10-29 Invatec S.P.A. Occlusion bypassing apparatus with varying flexibility and methods for bypassing an occlusion in a blood vessel
US10219936B2 (en) 2014-09-11 2019-03-05 Orbit Biomedical Limited Therapeutic agent delivery device with advanceable cannula and needle
US10064752B2 (en) 2014-09-11 2018-09-04 Orbit Biomedical Limited Motorized suprachoroidal injection of therapeutic agent
US10322028B2 (en) 2014-09-11 2019-06-18 Orbit Biomedical Limited Method and apparatus for sensing position between layers of an eye
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
GB201516066D0 (en) 2015-09-10 2015-10-28 Young & Co Llp D Treatment of retinitis pigmentosa
US10478553B2 (en) 2016-03-09 2019-11-19 Orbit Biomedical Limited Apparatus for subretinal administration of therapeutic agent via a curved needle

Also Published As

Publication number Publication date
EP3426203C0 (en) 2025-05-28
US20220288306A1 (en) 2022-09-15
EP3426203A1 (en) 2019-01-16
KR102608333B1 (ko) 2023-12-01
US11338084B2 (en) 2022-05-24
JP2023169335A (ja) 2023-11-29
CN108712894A (zh) 2018-10-26
CA3175975A1 (en) 2017-09-14
JP2019508212A (ja) 2019-03-28
KR102205295B1 (ko) 2021-01-22
KR20180122653A (ko) 2018-11-13
SG11201807191YA (en) 2018-09-27
CN108712894B (zh) 2021-09-10
US10478553B2 (en) 2019-11-19
JP7023873B2 (ja) 2022-02-22
WO2017156227A1 (en) 2017-09-14
IL261251A (en) 2018-10-31
KR20210008173A (ko) 2021-01-20
RU2018135286A (ru) 2020-04-09
SA518392352B1 (ar) 2022-01-13
JP2022017454A (ja) 2022-01-25
US20170258988A1 (en) 2017-09-14
AU2017229763A1 (en) 2018-09-06
KR20230163593A (ko) 2023-11-30
ES3031816T3 (en) 2025-07-11
US20200078514A1 (en) 2020-03-12
EP3426203B1 (en) 2025-05-28
AU2017229763B2 (en) 2021-06-10
RU2018135286A3 (enExample) 2020-06-11
CA3015529C (en) 2024-11-12
BR112018067896A2 (pt) 2019-03-19
CN113616417B (zh) 2024-10-18
CN113616417A (zh) 2021-11-09
CA3015529A1 (en) 2017-09-14
IL261251B (en) 2022-02-01
RU2740165C2 (ru) 2021-01-12

Similar Documents

Publication Publication Date Title
IL261251B (en) A device for subretinal administration of a therapeutic substance using a convex needle
ZA201908621B (en) Method and apparatus for delivery of therapeutic agents
PT3471672T (pt) Dispositivo injetor para administração subretinal de agente terapêutico
IL289611B (en) A device for subcutaneous administration of a liquid drug
PT3797742T (pt) Aparelho para administração supra-coroidal de agente terapêutico
EP3471670B8 (en) Apparatus to form entry bleb for subretinal delivery of therapeutic agent
IL277803A (en) Systems and methods for administering a therapeutic agent
IL262213A (en) Device and a method for controlled administering of a therapeutic composition to a patient
IL248756A0 (en) Devices and methods to assist the user of a drug delivery device
IL250250B (en) Device and method for delivering stimulation to body tissue
IL277150A (en) Devices for injecting drugs and methods of using them
EP3525864C0 (en) DEVICE FOR PLACING AN IMPLANT THROUGH A CATHETER
IL249694A0 (en) Apparatus and methods for sealing a drug within a medical delivery device
EP3141603A4 (en) Gpc3-targeted therapeutic agent for administration to patients for whom gpc3-targeted therapeutic agent therapy is effective
IL267622A (en) Method for modifying the therapeutic effects of drugs
EP3212170A4 (en) Implantable medical devices for extended release of therapeutic agents
SG11201608257RA (en) A device for a medical treatment of a sclera
IL254625A0 (en) Device for targeted delivery of a therapeutic implant
IL269001A (en) Device and methods for administering a nauseating compound from a drug delivery device
IL289544A (en) Methods for administering anti-fibrotic therapy
GB201511126D0 (en) Spray device for the delivery of therapeutic agents
GB201717625D0 (en) Device for treatment of chronic respiratory diseases
NO20161568A1 (en) A new drug delivery system for treatment of cancer
HK40126664A (en) Method and apparatus for suprachoroidal administration of therapeutic agent
GB201820637D0 (en) Engineered platelets for targeted delivery of a therapeutic agent