KR102608333B1 - 곡침을 통해 치료제를 망막하 투여하기 위한 장치 - Google Patents
곡침을 통해 치료제를 망막하 투여하기 위한 장치 Download PDFInfo
- Publication number
- KR102608333B1 KR102608333B1 KR1020217001164A KR20217001164A KR102608333B1 KR 102608333 B1 KR102608333 B1 KR 102608333B1 KR 1020217001164 A KR1020217001164 A KR 1020217001164A KR 20217001164 A KR20217001164 A KR 20217001164A KR 102608333 B1 KR102608333 B1 KR 102608333B1
- Authority
- KR
- South Korea
- Prior art keywords
- needle
- cannula
- distal
- choroid
- curvature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/008—Strength or flexibility characteristics of the catheter tip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0082—Catheter tip comprising a tool
- A61M25/0084—Catheter tip comprising a tool being one or more injection needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0113—Mechanical advancing means, e.g. catheter dispensers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
- A61M5/3291—Shafts with additional lateral openings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M2005/1585—Needle inserters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/587—Lighting arrangements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0612—Eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020237040321A KR20230163593A (ko) | 2016-03-09 | 2017-03-09 | 곡침을 통해 치료제를 망막하 투여하기 위한 장치 |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662305767P | 2016-03-09 | 2016-03-09 | |
| US62/305,767 | 2016-03-09 | ||
| US15/438,918 | 2017-02-22 | ||
| US15/438,918 US10478553B2 (en) | 2016-03-09 | 2017-02-22 | Apparatus for subretinal administration of therapeutic agent via a curved needle |
| PCT/US2017/021508 WO2017156227A1 (en) | 2016-03-09 | 2017-03-09 | Apparatus for subretinal administration of therapeutic agent via a curved needle |
| KR1020187028153A KR102205295B1 (ko) | 2016-03-09 | 2017-03-09 | 곡침을 통해 치료제를 망막하 투여하기 위한 장치 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187028153A Division KR102205295B1 (ko) | 2016-03-09 | 2017-03-09 | 곡침을 통해 치료제를 망막하 투여하기 위한 장치 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237040321A Division KR20230163593A (ko) | 2016-03-09 | 2017-03-09 | 곡침을 통해 치료제를 망막하 투여하기 위한 장치 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20210008173A KR20210008173A (ko) | 2021-01-20 |
| KR102608333B1 true KR102608333B1 (ko) | 2023-12-01 |
Family
ID=59788385
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217001164A Active KR102608333B1 (ko) | 2016-03-09 | 2017-03-09 | 곡침을 통해 치료제를 망막하 투여하기 위한 장치 |
| KR1020187028153A Active KR102205295B1 (ko) | 2016-03-09 | 2017-03-09 | 곡침을 통해 치료제를 망막하 투여하기 위한 장치 |
| KR1020237040321A Ceased KR20230163593A (ko) | 2016-03-09 | 2017-03-09 | 곡침을 통해 치료제를 망막하 투여하기 위한 장치 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187028153A Active KR102205295B1 (ko) | 2016-03-09 | 2017-03-09 | 곡침을 통해 치료제를 망막하 투여하기 위한 장치 |
| KR1020237040321A Ceased KR20230163593A (ko) | 2016-03-09 | 2017-03-09 | 곡침을 통해 치료제를 망막하 투여하기 위한 장치 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10478553B2 (enExample) |
| EP (1) | EP3426203B1 (enExample) |
| JP (3) | JP7023873B2 (enExample) |
| KR (3) | KR102608333B1 (enExample) |
| CN (2) | CN113616417B (enExample) |
| AU (1) | AU2017229763B2 (enExample) |
| BR (1) | BR112018067896A2 (enExample) |
| CA (2) | CA3175975A1 (enExample) |
| ES (1) | ES3031816T3 (enExample) |
| IL (1) | IL261251B (enExample) |
| RU (1) | RU2740165C2 (enExample) |
| SA (1) | SA518392352B1 (enExample) |
| SG (2) | SG11201807191YA (enExample) |
| WO (1) | WO2017156227A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10478553B2 (en) | 2016-03-09 | 2019-11-19 | Orbit Biomedical Limited | Apparatus for subretinal administration of therapeutic agent via a curved needle |
| US10646374B2 (en) | 2016-06-17 | 2020-05-12 | Orbit Biomedical Limited | Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent |
| US10806629B2 (en) | 2016-06-17 | 2020-10-20 | Gyroscope Therapeutics Limited | Injection device for subretinal delivery of therapeutic agent |
| US11076984B2 (en) | 2017-03-13 | 2021-08-03 | Gyroscope Therapeutics Limited | Method of performing subretinal drainage and agent delivery |
| US11033427B2 (en) | 2017-04-13 | 2021-06-15 | Alcon Inc. | Vitreoretinal instruments for fluid aspiration |
| GB201714392D0 (en) | 2017-09-07 | 2017-10-25 | Marsteller Laurence | Methods and devices for treating glaucoma |
| US10960147B2 (en) * | 2018-04-20 | 2021-03-30 | Flextronics Ap, Llc | Flex needle |
| EP3829501B1 (en) * | 2018-08-03 | 2025-12-31 | The Johns Hopkins University | RETINAL IMPLANTATION DEVICE |
| WO2020069217A1 (en) * | 2018-09-28 | 2020-04-02 | Radiance Therapeutics, Inc. | Methods, systems, and compositions for maintaining functioning drainage blebs associated with minimally invasive micro sclerostomy |
| EP3920859B1 (en) * | 2019-02-06 | 2025-09-03 | The Johns Hopkins University | External and internal intraoperative optical coherence tomography imaging for subretinal material delivery |
| US11759355B1 (en) | 2019-02-26 | 2023-09-19 | Gyroscope Therapeutics Limited | Method of delivering leading blebs and agent to subretinal space |
| EP4041147A1 (en) | 2019-10-11 | 2022-08-17 | Gyroscope Therapeutics Limited | Dose clip assembly for syringe |
| WO2022136913A1 (en) | 2020-12-22 | 2022-06-30 | Gyroscope Therapeutics Limited | Ocular cannula guide |
| USD1076086S1 (en) | 2021-11-23 | 2025-05-20 | Radiance Therapeutics, Inc. | Opthalmic brachytherapy device |
| USD1076085S1 (en) | 2021-11-23 | 2025-05-20 | Radiance Therapeutics, Inc. | Opthalmic brachytherapy device |
| KR20250065626A (ko) | 2022-09-06 | 2025-05-13 | 제넨테크, 인크. | 이중-곡선 니들을 통해 치료제를 망막하 투여하기 위한 장치 |
| KR20250138741A (ko) | 2023-01-13 | 2025-09-22 | 제넨테크, 인크. | 주사기용 용량 도킹 장치 |
| WO2024249805A1 (en) * | 2023-05-31 | 2024-12-05 | The Johns Hopkins University | Methods and systems for accessing anatomical spaces |
| US20240423836A1 (en) * | 2023-06-22 | 2024-12-26 | Alcon Inc. | Methods and apparatus for subretinal delivery |
| AU2024311612A1 (en) * | 2023-06-22 | 2025-11-13 | Alcon Inc. | Methods and apparatus for subretinal delivery |
| US20240423835A1 (en) * | 2023-06-22 | 2024-12-26 | Alcon Inc. | Methods and apparatus for subretinal delivery |
| TW202529711A (zh) | 2023-09-29 | 2025-08-01 | 美商建南德克公司 | 眼插管導引器、施用器及標記器械 |
| WO2025207699A1 (en) | 2024-03-27 | 2025-10-02 | Genentech, Inc. | Torque ring for subretinal injection device |
| WO2025217214A2 (en) | 2024-04-08 | 2025-10-16 | Regenxbio Inc. | Recombinant adeno-associated viruses and uses thereof |
| WO2025217230A1 (en) | 2024-04-08 | 2025-10-16 | Regenxbio Inc. | Vectorized anti-complement antibodies and complement agents and administration thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US20040138562A1 (en) * | 2002-01-17 | 2004-07-15 | Joshua Makower | Devices, systems and methods for acute or chronic delivery of substances or apparatus to extravascular treatment sites |
| US20100145278A1 (en) * | 2008-12-04 | 2010-06-10 | Abbott Cardiovascular Systems Inc. | Agent delivery catheter having articulating arms |
| WO2015126694A1 (en) * | 2014-02-12 | 2015-08-27 | Ethicon Endo-Surgery, Inc. | Method and apparatus for suprachoroidal administration of therapeutic agent |
| WO2015187629A1 (en) | 2014-06-06 | 2015-12-10 | Ethicon Endo-Surgery, Inc. | Sub-retinal tangential needle catheter guide and introducer |
| US20160074211A1 (en) | 2014-09-11 | 2016-03-17 | Ethicon Endo-Surgery, Inc. | Therapeutic agent delivery device with advanceable cannula and needle |
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| US5273530A (en) | 1990-11-14 | 1993-12-28 | The University Of Rochester | Intraretinal delivery and withdrawal instruments |
| DE4235506A1 (de) * | 1992-10-21 | 1994-04-28 | Bavaria Med Tech | Katheter zur Injektion von Arzneimitteln |
| US5964740A (en) * | 1996-07-09 | 1999-10-12 | Asahi Kogaku Kogyo Kabushiki Kaisha | Treatment accessory for an endoscope |
| KR19990064208A (ko) * | 1995-10-13 | 1999-07-26 | 트랜스바스큘라, 인코포레이티드 | 동맥 폐색부를 우회하고/거나 그 밖의 혈관 횡단 과정을 수행하기 위한 방법 및 장치 |
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| DE19741487C2 (de) | 1997-09-19 | 2000-08-31 | Univ Eberhard Karls | Vorrichtung für einen Zugang in den Subretinalraum eines Auges |
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| US6217554B1 (en) * | 1999-02-12 | 2001-04-17 | Pharmaspec Corporation | Methods and apparatus for delivering substances into extravascular tissue |
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| US6989004B2 (en) * | 2001-02-28 | 2006-01-24 | Rex Medical, L.P. | Apparatus for delivering ablation fluid to treat lesions |
| AU2003213075A1 (en) | 2002-02-14 | 2003-09-04 | Henry J. Kaplan | Subretinal implantation device and surgical cannulas for use therewith |
| US7316676B2 (en) * | 2002-08-20 | 2008-01-08 | Gholam A. Peyman | Treatment of retinal detachment |
| JP2006507368A (ja) | 2002-09-29 | 2006-03-02 | サーモディックス,インコーポレイティド | ステロイド含有治療剤の網膜下投与方法;脈絡膜及び網膜に薬力学作用を局在化するための方法;並びに網膜疾患の治療及び/又は予防のための関連する方法 |
| US20040199130A1 (en) * | 2003-04-03 | 2004-10-07 | Chornenky Victor I. | Apparatus and method for treatment of macular degeneration |
| JP4289919B2 (ja) * | 2003-05-06 | 2009-07-01 | 朝日インテック株式会社 | 薬液注入装置 |
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