BR112018067896A2 - aparelho para administração sub-retinal de agente terapêutico através de uma agulha curva - Google Patents

aparelho para administração sub-retinal de agente terapêutico através de uma agulha curva

Info

Publication number
BR112018067896A2
BR112018067896A2 BR112018067896-1A BR112018067896A BR112018067896A2 BR 112018067896 A2 BR112018067896 A2 BR 112018067896A2 BR 112018067896 A BR112018067896 A BR 112018067896A BR 112018067896 A2 BR112018067896 A2 BR 112018067896A2
Authority
BR
Brazil
Prior art keywords
needle
cannula
therapeutic agent
curved needle
subretinal administration
Prior art date
Application number
BR112018067896-1A
Other languages
English (en)
Portuguese (pt)
Inventor
E. Meyer Thomas
L. KO Benjamin
J. KHAN Isaac
W. Price Daniel
J. OBERKIRCHER Brendan
F. Keane Michael
Original Assignee
Orbit Biomedical Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orbit Biomedical Limited filed Critical Orbit Biomedical Limited
Publication of BR112018067896A2 publication Critical patent/BR112018067896A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/00736Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0026Ophthalmic product dispenser attachments to facilitate positioning near the eye
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/008Strength or flexibility characteristics of the catheter tip
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0082Catheter tip comprising a tool
    • A61M25/0084Catheter tip comprising a tool being one or more injection needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0113Mechanical advancing means, e.g. catheter dispensers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
    • A61M5/3291Shafts with additional lateral openings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1585Needle inserters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/587Lighting arrangements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0612Eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
BR112018067896-1A 2016-03-09 2017-03-09 aparelho para administração sub-retinal de agente terapêutico através de uma agulha curva BR112018067896A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662305767P 2016-03-09 2016-03-09
US62/305,767 2016-03-09
US15/438,918 2017-02-22
US15/438,918 US10478553B2 (en) 2016-03-09 2017-02-22 Apparatus for subretinal administration of therapeutic agent via a curved needle
PCT/US2017/021508 WO2017156227A1 (en) 2016-03-09 2017-03-09 Apparatus for subretinal administration of therapeutic agent via a curved needle

Publications (1)

Publication Number Publication Date
BR112018067896A2 true BR112018067896A2 (pt) 2019-03-19

Family

ID=59788385

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018067896-1A BR112018067896A2 (pt) 2016-03-09 2017-03-09 aparelho para administração sub-retinal de agente terapêutico através de uma agulha curva

Country Status (14)

Country Link
US (3) US10478553B2 (enExample)
EP (1) EP3426203B1 (enExample)
JP (3) JP7023873B2 (enExample)
KR (3) KR102608333B1 (enExample)
CN (2) CN113616417B (enExample)
AU (1) AU2017229763B2 (enExample)
BR (1) BR112018067896A2 (enExample)
CA (2) CA3175975A1 (enExample)
ES (1) ES3031816T3 (enExample)
IL (1) IL261251B (enExample)
RU (1) RU2740165C2 (enExample)
SA (1) SA518392352B1 (enExample)
SG (2) SG11201807191YA (enExample)
WO (1) WO2017156227A1 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10478553B2 (en) 2016-03-09 2019-11-19 Orbit Biomedical Limited Apparatus for subretinal administration of therapeutic agent via a curved needle
US10646374B2 (en) 2016-06-17 2020-05-12 Orbit Biomedical Limited Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent
US10806629B2 (en) 2016-06-17 2020-10-20 Gyroscope Therapeutics Limited Injection device for subretinal delivery of therapeutic agent
US11076984B2 (en) 2017-03-13 2021-08-03 Gyroscope Therapeutics Limited Method of performing subretinal drainage and agent delivery
US11033427B2 (en) 2017-04-13 2021-06-15 Alcon Inc. Vitreoretinal instruments for fluid aspiration
GB201714392D0 (en) 2017-09-07 2017-10-25 Marsteller Laurence Methods and devices for treating glaucoma
US10960147B2 (en) * 2018-04-20 2021-03-30 Flextronics Ap, Llc Flex needle
EP3829501B1 (en) * 2018-08-03 2025-12-31 The Johns Hopkins University RETINAL IMPLANTATION DEVICE
WO2020069217A1 (en) * 2018-09-28 2020-04-02 Radiance Therapeutics, Inc. Methods, systems, and compositions for maintaining functioning drainage blebs associated with minimally invasive micro sclerostomy
EP3920859B1 (en) * 2019-02-06 2025-09-03 The Johns Hopkins University External and internal intraoperative optical coherence tomography imaging for subretinal material delivery
US11759355B1 (en) 2019-02-26 2023-09-19 Gyroscope Therapeutics Limited Method of delivering leading blebs and agent to subretinal space
EP4041147A1 (en) 2019-10-11 2022-08-17 Gyroscope Therapeutics Limited Dose clip assembly for syringe
WO2022136913A1 (en) 2020-12-22 2022-06-30 Gyroscope Therapeutics Limited Ocular cannula guide
USD1076086S1 (en) 2021-11-23 2025-05-20 Radiance Therapeutics, Inc. Opthalmic brachytherapy device
USD1076085S1 (en) 2021-11-23 2025-05-20 Radiance Therapeutics, Inc. Opthalmic brachytherapy device
KR20250065626A (ko) 2022-09-06 2025-05-13 제넨테크, 인크. 이중-곡선 니들을 통해 치료제를 망막하 투여하기 위한 장치
KR20250138741A (ko) 2023-01-13 2025-09-22 제넨테크, 인크. 주사기용 용량 도킹 장치
WO2024249805A1 (en) * 2023-05-31 2024-12-05 The Johns Hopkins University Methods and systems for accessing anatomical spaces
US20240423836A1 (en) * 2023-06-22 2024-12-26 Alcon Inc. Methods and apparatus for subretinal delivery
AU2024311612A1 (en) * 2023-06-22 2025-11-13 Alcon Inc. Methods and apparatus for subretinal delivery
US20240423835A1 (en) * 2023-06-22 2024-12-26 Alcon Inc. Methods and apparatus for subretinal delivery
TW202529711A (zh) 2023-09-29 2025-08-01 美商建南德克公司 眼插管導引器、施用器及標記器械
WO2025207699A1 (en) 2024-03-27 2025-10-02 Genentech, Inc. Torque ring for subretinal injection device
WO2025217214A2 (en) 2024-04-08 2025-10-16 Regenxbio Inc. Recombinant adeno-associated viruses and uses thereof
WO2025217230A1 (en) 2024-04-08 2025-10-16 Regenxbio Inc. Vectorized anti-complement antibodies and complement agents and administration thereof

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5273530A (en) 1990-11-14 1993-12-28 The University Of Rochester Intraretinal delivery and withdrawal instruments
DE4235506A1 (de) * 1992-10-21 1994-04-28 Bavaria Med Tech Katheter zur Injektion von Arzneimitteln
US5964740A (en) * 1996-07-09 1999-10-12 Asahi Kogaku Kogyo Kabushiki Kaisha Treatment accessory for an endoscope
KR19990064208A (ko) * 1995-10-13 1999-07-26 트랜스바스큘라, 인코포레이티드 동맥 폐색부를 우회하고/거나 그 밖의 혈관 횡단 과정을 수행하기 위한 방법 및 장치
CN1204242A (zh) * 1995-10-13 1999-01-06 血管转换公司 为动脉阻塞物加设旁路和/或其他经血管操作的方法和装置
DE19741487C2 (de) 1997-09-19 2000-08-31 Univ Eberhard Karls Vorrichtung für einen Zugang in den Subretinalraum eines Auges
US6231546B1 (en) * 1998-01-13 2001-05-15 Lumend, Inc. Methods and apparatus for crossing total occlusions in blood vessels
JP3055504U (ja) * 1998-07-02 1999-01-22 株式会社八光電機製作所 眼球針
US6217554B1 (en) * 1999-02-12 2001-04-17 Pharmaspec Corporation Methods and apparatus for delivering substances into extravascular tissue
US6368315B1 (en) 1999-06-23 2002-04-09 Durect Corporation Composite drug delivery catheter
US6413245B1 (en) * 1999-10-21 2002-07-02 Alcon Universal Ltd. Sub-tenon drug delivery
US7357794B2 (en) * 2002-01-17 2008-04-15 Medtronic Vascular, Inc. Devices, systems and methods for acute or chronic delivery of substances or apparatus to extravascular treatment sites
US6989004B2 (en) * 2001-02-28 2006-01-24 Rex Medical, L.P. Apparatus for delivering ablation fluid to treat lesions
AU2003213075A1 (en) 2002-02-14 2003-09-04 Henry J. Kaplan Subretinal implantation device and surgical cannulas for use therewith
US7316676B2 (en) * 2002-08-20 2008-01-08 Gholam A. Peyman Treatment of retinal detachment
JP2006507368A (ja) 2002-09-29 2006-03-02 サーモディックス,インコーポレイティド ステロイド含有治療剤の網膜下投与方法;脈絡膜及び網膜に薬力学作用を局在化するための方法;並びに網膜疾患の治療及び/又は予防のための関連する方法
US20040199130A1 (en) * 2003-04-03 2004-10-07 Chornenky Victor I. Apparatus and method for treatment of macular degeneration
JP4289919B2 (ja) * 2003-05-06 2009-07-01 朝日インテック株式会社 薬液注入装置
IL156582A0 (en) * 2003-06-22 2004-01-04 Sergey Popov Safety trocar obturator
AU2004252568B2 (en) 2003-06-27 2011-06-30 Ethicon, Incorporated Regeneration and repair of neural tissue using postpartum-derived cells
GB0327136D0 (en) * 2003-11-21 2003-12-24 Nmt Group Plc Safety needle
KR101195052B1 (ko) 2004-01-23 2012-10-29 아이싸이언스 인터벤셔날 코포레이션 복합체 안과 마이크로캐뉼라
KR20070036044A (ko) * 2004-04-29 2007-04-02 아이싸이언스 인터벤셔날 코포레이션 안과 치료를 위한 장치와 방법
US20080058704A1 (en) 2004-04-29 2008-03-06 Michael Hee Apparatus and Method for Ocular Treatment
WO2007002304A2 (en) * 2005-06-22 2007-01-04 Vnus Medical Technologies, Inc. Methods and apparatus for introducing tumescent fluid to body tissue
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US20080004596A1 (en) * 2006-05-25 2008-01-03 Palo Alto Institute Delivery of agents by microneedle catheter
KR20090057984A (ko) * 2006-09-19 2009-06-08 더 트러스티이스 오브 콜롬비아 유니버시티 인 더 시티 오브 뉴욕 중공형 해부학적 부유 기관 상에서의 수술을 위한 시스템, 디바이스 및 방법
US20080281292A1 (en) 2006-10-16 2008-11-13 Hickingbotham Dyson W Retractable Injection Port
US8002743B2 (en) * 2007-06-15 2011-08-23 Kyphon Sarl Systems and methods for needle access to an intervertebral disc
EP2227257B1 (en) * 2008-01-07 2013-06-26 Salutaris Medical Devices, Inc. Devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye
WO2009089409A2 (en) 2008-01-10 2009-07-16 Bausch & Lomb Incorporated Intravitreal injection system having coaxial cannulae and use thereof
US8021332B2 (en) * 2008-12-04 2011-09-20 Abbott Cardiovascular Systems Inc. Agent delivery catheter having articulating arms
US8425473B2 (en) 2009-01-23 2013-04-23 Iscience Interventional Corporation Subretinal access device
WO2010132751A1 (en) 2009-05-15 2010-11-18 Iscience Interventional Corporation Methods and apparatus for sub-retinal catheterization
WO2010141837A1 (en) * 2009-06-05 2010-12-09 Vance Products Incorporated, D/B/A/ Cook Urological Incorporated Access sheath and needle assembly for delivering therapeutic material
CN106214321B (zh) 2010-10-15 2018-08-28 科尼尔赛德生物医学公司 用于进入眼睛的装置
GB2487899A (en) * 2011-02-01 2012-08-15 Olberon Ltd Needle holder with grip means
JP5717182B2 (ja) * 2011-02-25 2015-05-13 Hoya株式会社 眼科手術器具
US8852165B2 (en) * 2011-06-16 2014-10-07 II Edward G. Mackay Endoluminal drug delivery devices and methods
US9414816B2 (en) * 2011-06-23 2016-08-16 Devicor Medical Products, Inc. Introducer for biopsy device
US8938285B2 (en) * 2011-08-08 2015-01-20 Devicor Medical Products, Inc. Access chamber and markers for biopsy device
US9370447B2 (en) * 2011-10-10 2016-06-21 Cygnus LP Probes for use in ophthalmic and vitreoretinal surgery
WO2013059737A2 (en) * 2011-10-19 2013-04-25 Nitinol Devices And Components, Inc. Tissue treatment device and related methods
ES2533576T3 (es) * 2011-12-30 2015-04-13 Q-Med Ab Cánula sin hematomas
WO2013123309A1 (en) * 2012-02-15 2013-08-22 The Cleveland Clinic Foundation Catheter assembly and method of treating a vascular disease
US20150209180A1 (en) 2012-08-27 2015-07-30 Clearside Biomedical, Inc. Apparatus and Methods for Drug Delivery Using Microneedles
US9301795B2 (en) * 2012-10-29 2016-04-05 Ablative Solutions, Inc. Transvascular catheter for extravascular delivery
EP3721872B1 (en) 2012-11-08 2025-01-22 Clearside Biomedical Inc. Methods for the treatment of ocular disease in human subjects
KR102086103B1 (ko) * 2013-11-14 2020-03-06 아큐시스, 인코포레이티드 안구내 션트 삽입기
US10010447B2 (en) * 2013-12-18 2018-07-03 Novartis Ag Systems and methods for subretinal delivery of therapeutic agents
JP5777074B2 (ja) * 2013-12-24 2015-09-09 公立大学法人横浜市立大学 注射針
EP4555981A3 (en) * 2014-02-12 2025-08-06 Genentech, Inc. Method and apparatus for suprachoroidal administration of therapeutic agent
US9949874B2 (en) * 2014-06-06 2018-04-24 Janssen Biotech, Inc. Therapeutic agent delivery device with convergent lumen
US9925088B2 (en) 2014-06-06 2018-03-27 Janssen Biotech, Inc. Sub-retinal tangential needle catheter guide and introducer
CA2952822A1 (en) 2014-06-17 2015-12-23 Clearside Biomedical, Inc. Methods and devices for treating posterior ocular disorders
MX2016017028A (es) 2014-06-20 2017-08-07 Clearside Biomedical Inc Canula de diametro variable y metodos para el control de la profundidad de insercion para administracion de medicamentos.
US9949875B1 (en) * 2014-07-08 2018-04-24 Jeffrey N. Weiss Retinal and optic nerve autologous bone-marrow derived stem cell surgery
US10456557B2 (en) * 2014-08-14 2019-10-29 Invatec S.P.A. Occlusion bypassing apparatus with varying flexibility and methods for bypassing an occlusion in a blood vessel
US10064752B2 (en) 2014-09-11 2018-09-04 Orbit Biomedical Limited Motorized suprachoroidal injection of therapeutic agent
US10219936B2 (en) 2014-09-11 2019-03-05 Orbit Biomedical Limited Therapeutic agent delivery device with advanceable cannula and needle
US10322028B2 (en) 2014-09-11 2019-06-18 Orbit Biomedical Limited Method and apparatus for sensing position between layers of an eye
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
GB201516066D0 (en) 2015-09-10 2015-10-28 Young & Co Llp D Treatment of retinitis pigmentosa
US10478553B2 (en) * 2016-03-09 2019-11-19 Orbit Biomedical Limited Apparatus for subretinal administration of therapeutic agent via a curved needle

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US10478553B2 (en) 2019-11-19
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