SG10201911204WA - Autotaxin inhibitors and uses thereof - Google Patents
Autotaxin inhibitors and uses thereofInfo
- Publication number
- SG10201911204WA SG10201911204WA SG10201911204WA SG10201911204WA SG10201911204WA SG 10201911204W A SG10201911204W A SG 10201911204WA SG 10201911204W A SG10201911204W A SG 10201911204WA SG 10201911204W A SG10201911204W A SG 10201911204WA SG 10201911204W A SG10201911204W A SG 10201911204WA
- Authority
- SG
- Singapore
- Prior art keywords
- autotaxin inhibitors
- autotaxin
- inhibitors
- Prior art date
Links
- 102100021977 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 Human genes 0.000 title 1
- 108050004000 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562167216P | 2015-05-27 | 2015-05-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201911204WA true SG10201911204WA (en) | 2020-02-27 |
Family
ID=57393709
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201911204WA SG10201911204WA (en) | 2015-05-27 | 2016-05-24 | Autotaxin inhibitors and uses thereof |
Country Status (14)
Country | Link |
---|---|
US (2) | US10632104B2 (fr) |
EP (2) | EP4026549A1 (fr) |
JP (2) | JP6873919B2 (fr) |
CN (2) | CN116059203A (fr) |
AU (3) | AU2016268250B2 (fr) |
BR (1) | BR122023011445B1 (fr) |
CA (1) | CA2986759A1 (fr) |
EA (2) | EA039684B1 (fr) |
ES (1) | ES2915267T3 (fr) |
HK (1) | HK1253587A1 (fr) |
IL (2) | IL280863B1 (fr) |
MX (2) | MX2017015225A (fr) |
SG (1) | SG10201911204WA (fr) |
WO (1) | WO2016191427A1 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT3071561T (pt) | 2013-11-22 | 2021-06-25 | Sabre Therapeutics Llc | Compostos inibidores de autotaxina |
EP4026549A1 (fr) | 2015-05-27 | 2022-07-13 | Sabre Therapeutics LLC | Inhibiteurs de l'autotaxine et leurs utilisations |
CN107021915A (zh) * | 2017-04-27 | 2017-08-08 | 李亚庆 | 一种治疗妇科炎症的化合物及制备方法和应用 |
CA3072346A1 (fr) * | 2017-08-14 | 2019-02-21 | Camp4 Therapeutics Corporation | Procedes de traitement de maladies hepatiques |
CN112190708B (zh) * | 2019-07-08 | 2023-09-05 | 上海交通大学医学院附属瑞金医院 | 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用 |
CN114767863B (zh) * | 2022-04-29 | 2024-01-30 | 西北工业大学 | 一种enpp2基因或蛋白在调控结直肠癌细胞中的应用 |
WO2023215196A1 (fr) * | 2022-05-03 | 2023-11-09 | Sabre Therapeutics Llc | Formes polymorphes et formes salines de l'inhibiteur de l'autotaxine cudetaxestat |
WO2023215684A1 (fr) * | 2022-05-05 | 2023-11-09 | The Trustees Of Indiana University | Stratégies thérapeutiques pour gérer des contractures faciales après une lésion |
CN116239577A (zh) * | 2023-03-27 | 2023-06-09 | 沈阳药科大学 | 一种制备Cudetaxestat的方法 |
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