SG10201808165YA - Sample analysis for mass cytometry - Google Patents
Sample analysis for mass cytometryInfo
- Publication number
- SG10201808165YA SG10201808165YA SG10201808165YA SG10201808165YA SG10201808165YA SG 10201808165Y A SG10201808165Y A SG 10201808165YA SG 10201808165Y A SG10201808165Y A SG 10201808165YA SG 10201808165Y A SG10201808165Y A SG 10201808165YA SG 10201808165Y A SG10201808165Y A SG 10201808165YA
- Authority
- SG
- Singapore
- Prior art keywords
- mass cytometry
- sample analysis
- analysis
- icp
- devices
- Prior art date
Links
- 238000004458 analytical method Methods 0.000 title abstract 4
- 238000012083 mass cytometry Methods 0.000 title abstract 3
- 238000000095 laser ablation inductively coupled plasma mass spectrometry Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000002679 ablation Methods 0.000 abstract 1
- 238000009616 inductively coupled plasma Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
- G01N15/1436—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0459—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for solid samples
- H01J49/0463—Desorption by laser or particle beam, followed by ionisation as a separate step
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/10—Ion sources; Ion guns
- H01J49/105—Ion sources; Ion guns using high-frequency excitation, e.g. microwave excitation, Inductively Coupled Plasma [ICP]
-
- G01N15/01—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/40—Time-of-flight spectrometers
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361812893P | 2013-04-17 | 2013-04-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201808165YA true SG10201808165YA (en) | 2018-10-30 |
Family
ID=51730644
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201808165YA SG10201808165YA (en) | 2013-04-17 | 2014-04-17 | Sample analysis for mass cytometry |
SG11201504874QA SG11201504874QA (en) | 2013-04-17 | 2014-04-17 | Sample analysis for mass cytometry |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201504874QA SG11201504874QA (en) | 2013-04-17 | 2014-04-17 | Sample analysis for mass cytometry |
Country Status (8)
Country | Link |
---|---|
US (6) | US9589779B2 (ru) |
EP (2) | EP3690923A1 (ru) |
JP (1) | JP6230693B2 (ru) |
CN (1) | CN105190829B (ru) |
CA (2) | CA2895360C (ru) |
RU (1) | RU2637795C2 (ru) |
SG (2) | SG10201808165YA (ru) |
WO (1) | WO2014169394A1 (ru) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014146724A1 (en) | 2013-03-22 | 2014-09-25 | Eth Zurich | Laser ablation cell |
EP3690923A1 (en) | 2013-04-17 | 2020-08-05 | Fluidigm Canada Inc. | Sample analysis for mass cytometry |
CN105658310A (zh) | 2013-09-13 | 2016-06-08 | 斯坦福大学托管董事会 | 使用质量标签和次级离子质谱术的组织复用成像 |
GB201403625D0 (en) * | 2014-02-28 | 2014-04-16 | Asrepresented By The Sec Dep Of Health And Human Services The | Multiplexed imaging of tissue samples by mass cytometry |
WO2016042165A1 (en) * | 2014-09-18 | 2016-03-24 | Universiteit Gent | Laser ablation probe |
WO2016109825A1 (en) | 2014-12-31 | 2016-07-07 | Fluidigm Canada Inc. | Structured biological samples for analysis by mass cytometry |
US20160260598A1 (en) * | 2015-02-04 | 2016-09-08 | Fluidigm Canada Inc. | Laser enabled imaging mass cytometry |
US9766224B2 (en) | 2015-03-25 | 2017-09-19 | The Board Of Trustees Of The Leland Stanford Junior University | Single cell analysis using secondary ion mass spectrometry |
EP3286360A4 (en) | 2015-04-23 | 2018-11-21 | The Board of Trustees of The Leland Stanford Junior University | Method for multiplexed sample analysis by photoionizing secondary sputtered neutrals |
WO2018026898A1 (en) * | 2016-08-02 | 2018-02-08 | Fluidigm Canada Inc. | Laser ablation system |
CN110312486B (zh) * | 2016-12-22 | 2023-07-21 | 先进截骨工具 -Aot股份公司 | 激光设备和组织表征方法 |
US11092519B1 (en) * | 2017-02-06 | 2021-08-17 | Elemental Scientific Lasers, Llc | System and method for automated sampling and analysis |
JP7078382B2 (ja) * | 2017-11-22 | 2022-05-31 | 藤太郎 今坂 | 飛行時間型質量分析装置及び質量分析方法 |
EP3779399A4 (en) | 2018-04-18 | 2021-11-24 | S.T.Japan Inc. | LASER ABLATION DEVICE AND ANALYZER |
JP2021527828A (ja) * | 2018-06-18 | 2021-10-14 | フリューダイム カナダ インコーポレイテッド | 高解像度イメージング装置および方法 |
CN111954917B (zh) * | 2018-09-11 | 2023-11-07 | 株式会社 Lg新能源 | 接口单元 |
KR102577694B1 (ko) * | 2018-09-11 | 2023-09-12 | 주식회사 엘지에너지솔루션 | 검출 감도 향상을 위한 레이저 탈착-dart-ms 시스템 및 이에 사용되는 인터페이스 유닛 |
US20210404968A1 (en) * | 2018-10-29 | 2021-12-30 | Fluidigm Canada Inc. | Inductively coupled plasma torch with reverse vortex flow and method of operation |
CN109668818A (zh) * | 2018-12-26 | 2019-04-23 | 宁波大学 | 基于激光烧蚀的细胞分析装置及方法 |
US20210391161A1 (en) * | 2019-01-15 | 2021-12-16 | Fluidigm Canada Inc. | Direct ionization in imaging mass spectrometry operation |
WO2020228475A1 (en) * | 2019-05-15 | 2020-11-19 | Shanghai Polaris Biology Co., Ltd. | Sample transport apparatus for mass spectrometry |
US20220310373A1 (en) * | 2019-06-18 | 2022-09-29 | Fluidigm Canada Inc. | Improved mass cytometry |
GB2608031A (en) * | 2020-02-19 | 2022-12-21 | Elemental Scient Lasers Llc | Variable beam size via homqgenizer movement |
EP3943197A1 (en) * | 2020-07-20 | 2022-01-26 | The Provost, Fellows, Scholars and other Members of Board of Trinity College Dublin | Jet deposition using laser-produced dry aerosol |
JP2023544514A (ja) | 2020-09-18 | 2023-10-24 | フリューダイム カナダ インコーポレイテッド | 誘導結合プラズマに基づく原子分析システム及び方法 |
US11443933B1 (en) * | 2020-10-30 | 2022-09-13 | Agilent Technologies, Inc. | Inductively coupled plasma mass spectrometry (ICP-MS) with ion trapping |
JP2022131579A (ja) | 2021-02-26 | 2022-09-07 | キオクシア株式会社 | 分析装置および分析方法 |
CN113218846A (zh) * | 2021-03-18 | 2021-08-06 | 上海交通大学 | 一种面向于单细胞质谱流式分析的icp装置 |
CN117501408A (zh) * | 2021-04-14 | 2024-02-02 | 吉米亚分析公司 | 为icp-ms生成高产率负离子的系统 |
AT525093B1 (de) * | 2021-10-05 | 2022-12-15 | Univ Wien Tech | Vorrichtung zur Aufnahme eines Feststoff-Probenmaterials |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2177507B (en) | 1985-06-13 | 1989-02-15 | Mitsubishi Electric Corp | Laser mass spectroscopic analyzer |
DE4108462C2 (de) * | 1991-03-13 | 1994-10-13 | Bruker Franzen Analytik Gmbh | Verfahren und Vorrichtung zum Erzeugen von Ionen aus thermisch instabilen, nichtflüchtigen großen Molekülen |
DE4200497A1 (de) | 1992-01-10 | 1993-07-15 | Bayer Ag | Verfahren und vorrichtung zur schnellen identifizierung von kunststoffen mit hilfe der massenspektrometrie |
JP2870364B2 (ja) * | 1993-06-29 | 1999-03-17 | 日本鋼管株式会社 | レーザー気化分析方法及び装置 |
US5526110A (en) | 1994-07-08 | 1996-06-11 | Iowa State University Research Foundation, Inc. | In situ calibration of inductively coupled plasma-atomic emission and mass spectroscopy |
US5777324A (en) | 1996-09-19 | 1998-07-07 | Sequenom, Inc. | Method and apparatus for maldi analysis |
JPH11201945A (ja) * | 1998-01-09 | 1999-07-30 | Jeol Ltd | レーザーアブレーション装置 |
US5965884A (en) | 1998-06-04 | 1999-10-12 | The Regents Of The University Of California | Atmospheric pressure matrix assisted laser desorption |
JP2005502993A (ja) * | 2001-09-17 | 2005-01-27 | エムディーエス インコーポレイテッド ドゥーイング ビジネス アズ エムディーエス サイエックス | イオンの冷却・集束方法および装置 |
US6683277B1 (en) | 2002-12-20 | 2004-01-27 | Osram Opto Semiconductors | Laser ablation nozzle assembly |
US7217921B2 (en) * | 2004-01-22 | 2007-05-15 | Thermo Finnigan Llc | Method and apparatus for FAIMS for in-line analysis of multiple samples |
WO2005095942A1 (ja) | 2004-03-30 | 2005-10-13 | Riken | レーザーアブレーションを用いた生体試料の分析方法およびその装置 |
US7180058B1 (en) | 2005-10-05 | 2007-02-20 | Thermo Finnigan Llc | LDI/MALDI source for enhanced spatial resolution |
CA2658787C (en) | 2006-08-15 | 2013-04-09 | Alexei Antonov | Apparatus and method for elemental analysis of particles by mass spectrometry |
CA2668410C (en) | 2006-11-02 | 2017-05-16 | Mitchell A. Winnik | Particles containing detectable elemental code |
CA2673912A1 (en) * | 2006-12-29 | 2008-07-10 | Scott D. Tanner | Cell injector for flow cytometer having mass spectrometer detector and method for using same |
US8174691B1 (en) * | 2007-03-15 | 2012-05-08 | Arkansas State University—Jonesboro | Detection of a component of interest with an ultraviolet laser and method of using the same |
US9079268B2 (en) * | 2007-09-14 | 2015-07-14 | Robert C. Fry | Analytical laser ablation of solid samples for ICP, ICP-MS, and FAG-MS analysis |
US8207494B2 (en) * | 2008-05-01 | 2012-06-26 | Indiana University Research And Technology Corporation | Laser ablation flowing atmospheric-pressure afterglow for ambient mass spectrometry |
US9383260B1 (en) * | 2008-05-05 | 2016-07-05 | Applied Spectra, Inc. | Laser ablation analysis system |
DE102008049833A1 (de) * | 2008-10-01 | 2010-04-22 | Forschungszentrum Jülich GmbH | Verfahren und Vorrichtung zur Durchführung einer quantitativen ortsaufgelösten Lokal- und Verteilunganalyse chemischer Elemente und in-situ Charakterisierung der ablatierten Oberflächenregionen |
ES2741664T3 (es) * | 2009-02-02 | 2020-02-11 | Light Matter Interaction Inc | Método y sistema de desorción ablativa blanda |
DE102009016512B4 (de) * | 2009-04-08 | 2011-05-12 | Forschungszentrum Jülich GmbH | Verfahren und Vorrichtung zur Durchführung einer quantitativen ortsaufgelösten Lokal- und Verteilungsanalyse chemischer Elemente und in-situ Charakterisierung der ablatierten Oberflächenregionen |
WO2011006156A2 (en) * | 2009-07-10 | 2011-01-13 | University Of Florida Research Foundation, Inc. | Method and apparatus to laser ablation-laser induced breakdown spectroscopy |
DE202010010932U1 (de) * | 2010-04-19 | 2011-10-07 | Witec Wissenschaftliche Instrumente Und Technologie Gmbh | Vorrichtung zur Abbildung einer Probenoberfläche |
US8519330B2 (en) * | 2010-10-01 | 2013-08-27 | Ut-Battelle, Llc | Systems and methods for laser assisted sample transfer to solution for chemical analysis |
US8598488B2 (en) * | 2011-12-23 | 2013-12-03 | Electro Scientific Industries, Inc. | Method and apparatus for adjusting radiation spot size |
US8879064B2 (en) * | 2011-12-23 | 2014-11-04 | Electro Scientific Industries, Inc. | Apparatus and method for transporting an aerosol |
US9412574B2 (en) * | 2013-01-28 | 2016-08-09 | Westfaelische Wilhelms-Universitaet Muenster | Parallel elemental and molecular mass spectrometry analysis with laser ablation sampling |
EP2948974A2 (en) * | 2013-01-28 | 2015-12-02 | Westfälische Wilhelms-Universität Münster | Laser ablation atmospheric pressure ionization mass spectrometry |
US20140227776A1 (en) * | 2013-02-14 | 2014-08-14 | Electro Scientific Industries, Inc. | Laser ablation cell and torch system for a compositional analysis system |
US20140268134A1 (en) * | 2013-03-15 | 2014-09-18 | Electro Scientific Industries, Inc. | Laser sampling methods for reducing thermal effects |
WO2014146724A1 (en) | 2013-03-22 | 2014-09-25 | Eth Zurich | Laser ablation cell |
EP3690923A1 (en) | 2013-04-17 | 2020-08-05 | Fluidigm Canada Inc. | Sample analysis for mass cytometry |
US20160260598A1 (en) * | 2015-02-04 | 2016-09-08 | Fluidigm Canada Inc. | Laser enabled imaging mass cytometry |
-
2014
- 2014-04-17 EP EP20150581.5A patent/EP3690923A1/en active Pending
- 2014-04-17 WO PCT/CA2014/050387 patent/WO2014169394A1/en active Application Filing
- 2014-04-17 CA CA2895360A patent/CA2895360C/en active Active
- 2014-04-17 CA CA3191952A patent/CA3191952A1/en active Pending
- 2014-04-17 SG SG10201808165YA patent/SG10201808165YA/en unknown
- 2014-04-17 CN CN201480009995.6A patent/CN105190829B/zh active Active
- 2014-04-17 US US14/783,791 patent/US9589779B2/en active Active
- 2014-04-17 JP JP2016507962A patent/JP6230693B2/ja active Active
- 2014-04-17 EP EP14784995.4A patent/EP2987177B1/en active Active
- 2014-04-17 SG SG11201504874QA patent/SG11201504874QA/en unknown
- 2014-04-17 RU RU2015123440A patent/RU2637795C2/ru active
-
2017
- 2017-01-18 US US15/408,806 patent/US9952132B2/en active Active
-
2018
- 2018-04-18 US US15/956,403 patent/US10241023B2/en active Active
-
2019
- 2019-02-07 US US16/270,421 patent/US10705006B2/en active Active
-
2020
- 2020-06-08 US US16/895,009 patent/US11099116B2/en active Active
-
2021
- 2021-07-22 US US17/382,764 patent/US11630050B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20190271630A1 (en) | 2019-09-05 |
US11630050B2 (en) | 2023-04-18 |
EP2987177B1 (en) | 2020-01-08 |
US10241023B2 (en) | 2019-03-26 |
SG11201504874QA (en) | 2015-07-30 |
EP2987177A1 (en) | 2016-02-24 |
US20160056031A1 (en) | 2016-02-25 |
CA2895360A1 (en) | 2014-10-23 |
EP2987177A4 (en) | 2016-11-30 |
US10705006B2 (en) | 2020-07-07 |
CA3191952A1 (en) | 2014-10-23 |
EP3690923A1 (en) | 2020-08-05 |
CA2895360C (en) | 2023-05-02 |
JP2016522887A (ja) | 2016-08-04 |
US20170248507A1 (en) | 2017-08-31 |
US9589779B2 (en) | 2017-03-07 |
RU2015123440A (ru) | 2017-05-22 |
JP6230693B2 (ja) | 2017-11-15 |
CN105190829B (zh) | 2018-04-03 |
US20220178809A1 (en) | 2022-06-09 |
US11099116B2 (en) | 2021-08-24 |
US9952132B2 (en) | 2018-04-24 |
CN105190829A (zh) | 2015-12-23 |
RU2637795C2 (ru) | 2017-12-07 |
US20200408662A1 (en) | 2020-12-31 |
US20180306695A1 (en) | 2018-10-25 |
WO2014169394A1 (en) | 2014-10-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG10201808165YA (en) | Sample analysis for mass cytometry | |
EP3523651A4 (en) | DEVICES AND METHODS FOR SAMPLE ANALYSIS | |
EP3523640A4 (en) | DEVICES AND METHODS FOR SAMPLE ANALYSIS | |
MX2015010391A (es) | Dispositivo de muestreo y registro de almacenamiento para analisis de gas de respiracion. | |
EP3161161A4 (en) | Methods and compositions for sample analysis | |
EP3209410A4 (en) | Systems and methods for sample preparation, processing and analysis | |
EP3207499A4 (en) | Methods and systems for classifying biological samples, including optimization of analyses and use of correlation | |
MX2015017331A (es) | Anticuerpos anti fc similar a receptor 5 (fcrh5). | |
MX2019007742A (es) | Metodos para aislar microvesiculas. | |
EP3149464A4 (en) | System and method for electronic biological sample analysis | |
MX362545B (es) | Analisis de imagen y medicion de muestras biologicas. | |
EP3173786A4 (en) | Analysis method for diluted biological sample component | |
EP3512862A4 (en) | DEVICES AND METHOD FOR SAMPLE ANALYSIS | |
EP3240885A4 (en) | STRUCTURED BIOLOGICAL SAMPLES FOR ANALYSIS BY A MASS CYTOMETER | |
EP3232203A4 (en) | Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system | |
EP3039416A4 (en) | Method and apparatus for isolation, capture and molecular analysis of target particles | |
EP3256849A4 (en) | Devices, solutions and methods for sample collection related applications, analysis and diagnosis | |
EP3404397A4 (en) | SAMPLE SAMPLING DEVICE, SAMPLE SAMPLING DEVICE SUPPORT, AND SAMPLE PRE-PROCESSING METHOD USING THE SAMPLE COLLECTION DEVICE | |
EP3399319A4 (en) | Specimen analysis substrate, specimen analysis device, specimen analysis system, and program for specimen analysis system | |
EP3163306A4 (en) | Substrate for sample analysis, and sample analysis apparatus | |
PL2789007T3 (pl) | Układy, urządzenia i sposoby do analizy próbki z wykorzystaniem spektrometrii mas | |
MX2016008447A (es) | Metodos y sistemas para amplificacion de acido nucleico. | |
GB2562858B (en) | Method for the cytometric analysis of cell samples | |
HK1217990A1 (zh) | 用於樣品分析的方法、裝置和系統 | |
EP3045913A4 (en) | Sample processing method for influenza virus immunoassay, and immunoassay method |