SG10201802647QA - Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives - Google Patents

Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives

Info

Publication number
SG10201802647QA
SG10201802647QA SG10201802647QA SG10201802647QA SG10201802647QA SG 10201802647Q A SG10201802647Q A SG 10201802647QA SG 10201802647Q A SG10201802647Q A SG 10201802647QA SG 10201802647Q A SG10201802647Q A SG 10201802647QA SG 10201802647Q A SG10201802647Q A SG 10201802647QA
Authority
SG
Singapore
Prior art keywords
glutarimide derivatives
methods
pharmaceutical composition
composition based
producing
Prior art date
Application number
SG10201802647QA
Other languages
English (en)
Inventor
Vladimir Evgenievich Nebolsin
Tatyana Alexandrovna Kromova
Original Assignee
Obschestvo S Ogranichennoi Otvetstvennostiyu Pharmenterprises
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU2013116826A external-priority patent/RU2562773C3/ru
Application filed by Obschestvo S Ogranichennoi Otvetstvennostiyu Pharmenterprises filed Critical Obschestvo S Ogranichennoi Otvetstvennostiyu Pharmenterprises
Publication of SG10201802647QA publication Critical patent/SG10201802647QA/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG10201802647QA 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives SG10201802647QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2013116826A RU2562773C3 (ru) 2013-04-12 Производные глутаримидов, их применение, фармацевтическая композиция на их основе, способы их получения

Publications (1)

Publication Number Publication Date
SG10201802647QA true SG10201802647QA (en) 2018-05-30

Family

ID=51689819

Family Applications (4)

Application Number Title Priority Date Filing Date
SG10201802650WA SG10201802650WA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
SG10201802647QA SG10201802647QA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
SG10201802648SA SG10201802648SA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
SG11201508394UA SG11201508394UA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives

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SG10201802650WA SG10201802650WA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives

Family Applications After (2)

Application Number Title Priority Date Filing Date
SG10201802648SA SG10201802648SA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
SG11201508394UA SG11201508394UA (en) 2013-04-12 2014-04-10 Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives

Country Status (15)

Country Link
US (8) US9815814B2 (fr)
EP (3) EP2985282A4 (fr)
JP (4) JP6529958B2 (fr)
KR (3) KR102296182B1 (fr)
CN (4) CN110128406B (fr)
AU (5) AU2014251442A1 (fr)
BR (3) BR122020010210B1 (fr)
CA (1) CA2909057C (fr)
EA (4) EA031392B1 (fr)
IL (4) IL266301B2 (fr)
MX (4) MX2020005738A (fr)
SG (4) SG10201802650WA (fr)
UA (1) UA121299C2 (fr)
WO (1) WO2014168522A1 (fr)
ZA (3) ZA201508278B (fr)

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RU2552929C1 (ru) 2013-11-14 2015-06-10 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Фармацевтическая композиция, содержащая производные глутаримидов, и их применение для лечения эозинофильных заболеваний
RU2628800C2 (ru) * 2014-03-12 2017-08-22 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Амидные соединения, способы получения, применение в качестве средств для лечения и профилактики заболеваний, вызываемых рнк-содержащими вирусами
CN106539792B (zh) * 2016-11-07 2017-08-25 王晓旭 一种治疗高血脂症的药物
EA201992341A8 (ru) * 2017-09-07 2020-08-11 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Применение производного глутаримида для лечения заболеваний, связанных с аберрантной активностью цитокинов
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RU2712281C1 (ru) 2018-11-23 2020-01-28 Общество С Ограниченной Ответственностью "Хемиммьюн Терапьютикс" Применение производного глутаримида для преодоления резистентности к стероидам и терапии заболеваний, ассоциированных с аберрантным сигналингом интерферона гамма
BR112022026356A2 (pt) * 2020-06-26 2023-01-17 Valenta Intellekt Ltd Uso de um derivado de glutarimida para tratar doenças associadas à atividade aberrante da interleucina-6
WO2023121519A1 (fr) * 2021-12-23 2023-06-29 Общество С Ограниченной Ответственностью "Валента-Интеллект" Utilisation de 1-[2-(1-méthyylimidazol-4-yl)-éthyl]perhydroazine-2,6-dione pour le traitement de la covid-19
WO2023177329A1 (fr) * 2022-03-18 2023-09-21 Общество С Ограниченной Ответственностью "Валента-Интеллект" Utilisation de 1-(2-(1н-imidazol-4-yl)éthyl)pipéridine-2,6-dione pour le traitement de la toux induite par des infections virales
WO2023191666A1 (fr) * 2022-03-29 2023-10-05 Общество С Ограниченной Ответственностью "Валента-Интеллект" Forme cristalline de 1-(2-(1н-imidazol-4-yl)éthyl)pipéridine-2,6-dione, et utilisation de celle-ci

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EP3725785A1 (fr) 2020-10-21
KR102255929B1 (ko) 2021-05-26
EP3725785B1 (fr) 2024-04-10
KR20160021092A (ko) 2016-02-24
JP2019034964A (ja) 2019-03-07
KR102296182B1 (ko) 2021-09-02
AU2018236805A1 (en) 2018-10-18
KR20200069380A (ko) 2020-06-16
EA033054B1 (ru) 2019-08-30
AU2020203630A1 (en) 2020-06-25
EA201792072A3 (ru) 2018-09-28
AU2014251442A1 (en) 2015-12-03
AU2020203968A1 (en) 2020-07-02
IL266301B (en) 2022-11-01
CN110128406B (zh) 2021-08-27
CN110229140A (zh) 2019-09-13
IL266301B2 (en) 2023-03-01
JP6627039B2 (ja) 2020-01-08
EA031392B1 (ru) 2018-12-28
EA201591957A1 (ru) 2016-02-29
KR20200069381A (ko) 2020-06-16
RU2013116826A (ru) 2014-10-20
EA032938B1 (ru) 2019-08-30
KR102254315B1 (ko) 2021-05-25
SG10201802648SA (en) 2018-05-30
EP2985282A4 (fr) 2017-02-22
AU2020203968B2 (en) 2021-04-22
MX2020005736A (es) 2021-06-14
IL266300B (en) 2021-10-31
EA201792072A2 (ru) 2018-04-30
WO2014168522A1 (fr) 2014-10-16
BR112015025804A2 (pt) 2017-07-25
SG11201508394UA (en) 2015-11-27
ZA201603109B (en) 2017-08-30
SG10201802650WA (en) 2018-05-30
MX2020005738A (es) 2021-08-13
US20180016255A1 (en) 2018-01-18
IL266300A (en) 2019-06-30
IL266302B (en) 2021-09-30
JP2019034965A (ja) 2019-03-07
EA201792597A2 (ru) 2018-04-30
EP3725785C0 (fr) 2024-04-10
US10155746B2 (en) 2018-12-18
US10155744B2 (en) 2018-12-18
AU2018236805C1 (en) 2020-11-05
ZA201508278B (en) 2017-11-29
JP2019034966A (ja) 2019-03-07
US10155743B2 (en) 2018-12-18
MX2015014336A (es) 2016-06-07
AU2020203630B2 (en) 2021-04-22
JP6529958B2 (ja) 2019-06-12
US10196377B2 (en) 2019-02-05
US20180016254A1 (en) 2018-01-18
CN106061962A (zh) 2016-10-26
AU2020203632B2 (en) 2021-04-22
IL266301A (en) 2019-06-30
BR122020010204B1 (pt) 2022-03-03
US20180016257A1 (en) 2018-01-18
RU2562773C2 (ru) 2015-09-10
BR122020010210B1 (pt) 2022-09-20
EA201792071A3 (ru) 2018-09-28
CN110172055B (zh) 2021-10-29
CA2909057C (fr) 2022-03-22
US20180016253A1 (en) 2018-01-18
EA032951B1 (ru) 2019-08-30
ZA201603108B (en) 2017-08-30
IL241998B (en) 2019-06-30
UA121299C2 (uk) 2020-05-12
US10377739B2 (en) 2019-08-13
US10155745B2 (en) 2018-12-18
EA201792071A2 (ru) 2018-04-30
EP3722290B1 (fr) 2023-06-21
JP6843103B2 (ja) 2021-03-17
US20190084961A1 (en) 2019-03-21
MX2020005735A (es) 2021-06-21
AU2020203632A1 (en) 2020-06-25
US20160046598A1 (en) 2016-02-18
US10155747B2 (en) 2018-12-18
IL266302A (en) 2019-06-30
EP2985282A1 (fr) 2016-02-17
US20180022728A1 (en) 2018-01-25
US9815814B2 (en) 2017-11-14
EP3722290A1 (fr) 2020-10-14
US20180016256A1 (en) 2018-01-18
WO2014168522A4 (fr) 2015-01-22
JP6620324B2 (ja) 2019-12-18
CN110128406A (zh) 2019-08-16
AU2018236805B2 (en) 2020-04-09
BR112015025804B1 (pt) 2022-01-04
CN110172055A (zh) 2019-08-27
CN110229140B (zh) 2022-06-10
EA201792597A3 (ru) 2018-09-28
JP2016516766A (ja) 2016-06-09
CA2909057A1 (fr) 2014-10-16
CN106061962B (zh) 2019-09-06
WO2014168522A9 (fr) 2014-12-04

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