SG10201705761YA - Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators - Google Patents
Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulatorsInfo
- Publication number
- SG10201705761YA SG10201705761YA SG10201705761YA SG10201705761YA SG10201705761YA SG 10201705761Y A SG10201705761Y A SG 10201705761YA SG 10201705761Y A SG10201705761Y A SG 10201705761YA SG 10201705761Y A SG10201705761Y A SG 10201705761YA SG 10201705761Y A SG10201705761Y A SG 10201705761YA
- Authority
- SG
- Singapore
- Prior art keywords
- treatment
- combination
- estrogen receptor
- receptor modulators
- selective estrogen
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
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- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
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- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
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- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Neurology (AREA)
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- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Gynecology & Obstetrics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pregnancy & Childbirth (AREA)
- Child & Adolescent Psychology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18754909P | 2009-06-16 | 2009-06-16 | |
US12/791,174 US20100317635A1 (en) | 2009-06-16 | 2010-06-01 | Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201705761YA true SG10201705761YA (en) | 2017-08-30 |
Family
ID=43306950
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201912379PA SG10201912379PA (en) | 2009-06-16 | 2010-06-16 | Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators |
SG2012000410A SG177497A1 (en) | 2009-06-16 | 2010-06-16 | Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators |
SG10201705761YA SG10201705761YA (en) | 2009-06-16 | 2010-06-16 | Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201912379PA SG10201912379PA (en) | 2009-06-16 | 2010-06-16 | Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators |
SG2012000410A SG177497A1 (en) | 2009-06-16 | 2010-06-16 | Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators |
Country Status (20)
Country | Link |
---|---|
US (4) | US20100317635A1 (ja) |
EP (3) | EP2442807A4 (ja) |
JP (4) | JP2012530074A (ja) |
KR (10) | KR20190025752A (ja) |
CN (3) | CN104352504A (ja) |
AR (1) | AR077119A1 (ja) |
AU (1) | AU2010262722A1 (ja) |
BR (1) | BRPI1011561A2 (ja) |
CA (2) | CA2893236A1 (ja) |
CL (1) | CL2011003172A1 (ja) |
EA (1) | EA201200016A1 (ja) |
HK (1) | HK1204550A1 (ja) |
IL (2) | IL216963A (ja) |
MA (1) | MA33434B1 (ja) |
MX (1) | MX338290B (ja) |
NZ (1) | NZ597583A (ja) |
SG (3) | SG10201912379PA (ja) |
TW (1) | TWI612044B (ja) |
WO (1) | WO2010145010A1 (ja) |
ZA (1) | ZA201109198B (ja) |
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Publication number | Priority date | Publication date | Assignee | Title |
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US8268806B2 (en) | 2007-08-10 | 2012-09-18 | Endorecherche, Inc. | Pharmaceutical compositions |
US8703810B2 (en) | 2010-06-10 | 2014-04-22 | Seragon Pharmaceuticals, Inc. | Estrogen receptor modulators and uses thereof |
EP2734193B1 (en) * | 2011-07-19 | 2015-05-20 | Pantarhei Bioscience B.V. | Tablet containing dehydroepiandrosterone (dhea) |
AU2012351942B2 (en) | 2011-12-14 | 2017-07-06 | Seragon Pharmaceuticals, Inc. | Fluorinated estrogen receptor modulators and uses thereof |
AP2014007657A0 (en) | 2011-12-16 | 2014-05-31 | Olema Pharmaceuticals Inc | Novel benzopyran compounds, compositions and uses thereof |
WO2013134311A1 (en) * | 2012-03-07 | 2013-09-12 | Ligand Pharmaceuticals, Inc. | Steroid hormone and cholesterol pathways as one unified homestatic system |
WO2014008159A1 (en) * | 2012-07-03 | 2014-01-09 | The University Of North Carolina At Chapel Hill | Selective estrogen receptor degraders for treatment of tamoxifen resistant tumors |
WO2014203129A1 (en) | 2013-06-19 | 2014-12-24 | Olema Pharmaceuticals, Inc. | Combinations of benzopyran compounds, compositions and uses thereof |
WO2014203132A1 (en) | 2013-06-19 | 2014-12-24 | Olema Pharmaceuticals, Inc. | Substituted benzopyran compounds, compositions and uses thereof |
CN103739456A (zh) * | 2013-12-03 | 2014-04-23 | 镇江圣安医药有限公司 | 2-(对-((z-4-氯-1,2-二苯基-1-丁烯基)苯氧基)乙醇的新型衍生物及其应用 |
US9744177B2 (en) | 2014-03-10 | 2017-08-29 | Endorecherche, Inc. | Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM |
CN107530273B (zh) | 2015-04-28 | 2021-07-09 | 库泰克有限责任公司 | 含有缬草提取物的组合物 |
JP6855475B2 (ja) | 2015-10-27 | 2021-04-07 | スン プハルマ アドバンセド リサーチ カンパニー リミテド | 新規ヘテロ環状抗エストロゲン剤 |
WO2017162206A1 (zh) * | 2016-03-25 | 2017-09-28 | 南京明德新药研发股份有限公司 | 作为雌激素受体降解剂的吲哚并取代哌啶类化合物 |
BR112018072286A2 (pt) | 2016-04-29 | 2019-02-12 | Yale University | medida direcionada de atividade transcricional relacionada a receptores de hormônios |
WO2017201508A1 (en) | 2016-05-20 | 2017-11-23 | Azure Biotech, Inc. | Vaginal delivery systems containing selective estrogen receptor modulator (serm) and uses thereof |
SG11202002105WA (en) | 2017-09-11 | 2020-04-29 | Atossa Therapeutics Inc | Methods for making and using endoxifen |
CN111212631A (zh) * | 2017-09-11 | 2020-05-29 | 阿托莎医疗公司 | 局部用组合物和治疗方法 |
WO2022203097A1 (ko) * | 2021-03-24 | 2022-09-29 | 디어젠 주식회사 | 스트레스 과립의 조절제인 atxn2를 제어하여 tdp-43 단백질의 과잉생산을 억제하는 중추신경계질환의 예방 및 치료 조성물 |
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US60503A (en) | 1866-12-18 | Improvement in olaips foe gluing the tips on billiard cues | ||
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US3742951A (en) * | 1971-08-09 | 1973-07-03 | Alza Corp | Bandage for controlled release of vasodilators |
DE3333240A1 (de) * | 1983-09-12 | 1985-03-28 | Schering AG, 1000 Berlin und 4709 Bergkamen | Mittel zur transdermalen applikation von arzneimittelwirkstoffen |
CA1254514A (en) | 1984-06-29 | 1989-05-23 | Eugene Roberts | Method for promoting nerve regeneration |
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