SG10201703677VA - Methods of treating s. aureus-associated diseases - Google Patents

Methods of treating s. aureus-associated diseases

Info

Publication number
SG10201703677VA
SG10201703677VA SG10201703677VA SG10201703677VA SG10201703677VA SG 10201703677V A SG10201703677V A SG 10201703677VA SG 10201703677V A SG10201703677V A SG 10201703677VA SG 10201703677V A SG10201703677V A SG 10201703677VA SG 10201703677V A SG10201703677V A SG 10201703677VA
Authority
SG
Singapore
Prior art keywords
aureus
treating
methods
associated diseases
diseases
Prior art date
Application number
SG10201703677VA
Other languages
English (en)
Inventor
Bret Sellman
Christine Tkaczyk
Melissa Hamilton
Lei Hua
Original Assignee
Medimmune Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Llc filed Critical Medimmune Llc
Publication of SG10201703677VA publication Critical patent/SG10201703677VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/085Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SG10201703677VA 2012-11-06 2013-11-05 Methods of treating s. aureus-associated diseases SG10201703677VA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261723128P 2012-11-06 2012-11-06

Publications (1)

Publication Number Publication Date
SG10201703677VA true SG10201703677VA (en) 2017-06-29

Family

ID=50685101

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201703677VA SG10201703677VA (en) 2012-11-06 2013-11-05 Methods of treating s. aureus-associated diseases
SG11201503231YA SG11201503231YA (en) 2012-11-06 2013-11-05 METHODS OF TREATING <i>S. AUREUS</i>-ASSOCIATED DISEASES

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201503231YA SG11201503231YA (en) 2012-11-06 2013-11-05 METHODS OF TREATING <i>S. AUREUS</i>-ASSOCIATED DISEASES

Country Status (13)

Country Link
US (3) US9845348B2 (enExample)
EP (1) EP2928490B1 (enExample)
JP (2) JP6506172B2 (enExample)
KR (3) KR102272744B1 (enExample)
CN (2) CN104780934A (enExample)
AU (2) AU2013341421A1 (enExample)
BR (1) BR112015010126B1 (enExample)
CA (1) CA2890385C (enExample)
ES (1) ES2912267T3 (enExample)
MX (1) MX367082B (enExample)
RU (1) RU2661406C2 (enExample)
SG (2) SG10201703677VA (enExample)
WO (1) WO2014074470A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20180458T1 (hr) 2011-06-10 2018-06-29 Medimmune Limited Molekule koje vežu anti-pseudomonas psl i njihova uporaba
AU2012336028A1 (en) * 2011-11-07 2014-06-26 Medimmune, Llc Combination therapies using anti- Pseudomonas Psl and PcrV binding molecules
ES2776179T3 (es) * 2012-11-06 2020-07-29 Medimmune Llc Anticuerpos dirigidos contra determinantes de la superficie de S. aureus
RU2661406C2 (ru) * 2012-11-06 2018-07-16 МЕДИММЬЮН, ЭлЭлСи Способы лечения заболеваний, ассоциированных с s. aureus
TWI719938B (zh) 2014-06-19 2021-03-01 美商麥迪紐有限責任公司 多重細菌感染之治療
TW202311284A (zh) 2017-01-03 2023-03-16 美商再生元醫藥公司 抗金黃色葡萄球菌溶血素a毒素之人類抗體
WO2020023644A2 (en) 2018-07-24 2020-01-30 Medimmune, Llc Antibody directed against s. aureus clumping factor a (clfa)
CN113164602A (zh) 2018-10-09 2021-07-23 免疫医疗有限责任公司 抗金黄色葡萄球菌抗体的组合
AU2019359207A1 (en) 2018-10-09 2021-05-20 Humabs Biomed Sa Antibodies directed against Staphylococcus aureus leukotoxins
WO2020185986A1 (en) 2019-03-13 2020-09-17 Medimmune, Llc Decreasing staphylococcus aureus infections in colonized patients
CN112538112B (zh) * 2019-09-20 2023-10-27 迈威(上海)生物科技股份有限公司 抗α-溶血素的抗体及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2719397A1 (en) 2006-06-12 2014-04-16 GlaxoSmithKline Biologicals SA Use of alpha-toxin for treating and preventing staphylococcus infections
KR20100072228A (ko) 2007-08-31 2010-06-30 유니버시티 오브 시카고 스타필로코커스 폐 질환 및 상태에 대한 면역화와 관련된 방법 및 조성물
WO2011008939A2 (en) * 2009-07-16 2011-01-20 Medical College Of Georgia Research Institute, Inc. Porous-wall hollow glass microspheres as carriers for biomolecules
EP2284193A1 (en) 2009-08-10 2011-02-16 Kenta Biotech AG Human monoclonal antibody against S. aureus derived apha-toxin and its use in treating or preventing abscess formation
WO2012109167A1 (en) 2011-02-08 2012-08-16 Integrated Biotherapeutics, Inc. Immunogenic composition comprising alpha-hemolysin oligopeptides
US9527905B2 (en) 2011-02-08 2016-12-27 Medimmune, Llc Antibodies that specifically bind Staphylococcus aureus alpha toxin and methods of use
ES2776179T3 (es) 2012-11-06 2020-07-29 Medimmune Llc Anticuerpos dirigidos contra determinantes de la superficie de S. aureus
RU2661406C2 (ru) * 2012-11-06 2018-07-16 МЕДИММЬЮН, ЭлЭлСи Способы лечения заболеваний, ассоциированных с s. aureus
TWI719938B (zh) 2014-06-19 2021-03-01 美商麥迪紐有限責任公司 多重細菌感染之治療
WO2017075188A2 (en) 2015-10-30 2017-05-04 Medimmune, Llc Methods of using anti-alpha toxin antibody

Also Published As

Publication number Publication date
HK1215173A1 (zh) 2016-08-19
AU2013341421A1 (en) 2015-06-04
JP6926138B2 (ja) 2021-08-25
AU2018236849B2 (en) 2020-05-21
US9845348B2 (en) 2017-12-19
WO2014074470A1 (en) 2014-05-15
AU2018236849A1 (en) 2018-10-18
BR112015010126A2 (enExample) 2017-08-22
ES2912267T3 (es) 2022-05-25
EP2928490A4 (en) 2016-11-02
SG11201503231YA (en) 2015-05-28
KR20200102533A (ko) 2020-08-31
JP2019142888A (ja) 2019-08-29
EP2928490A1 (en) 2015-10-14
MX367082B (es) 2019-08-05
MX2015005481A (es) 2016-01-14
US20200109191A1 (en) 2020-04-09
US20160257733A1 (en) 2016-09-08
US10759849B2 (en) 2020-09-01
RU2015121617A (ru) 2016-12-27
EP2928490B1 (en) 2022-03-30
JP2015536951A (ja) 2015-12-24
CN104780934A (zh) 2015-07-15
CA2890385C (en) 2022-07-12
CA2890385A1 (en) 2014-05-15
CN112316135A (zh) 2021-02-05
KR20210083389A (ko) 2021-07-06
KR20150092738A (ko) 2015-08-13
KR102272744B1 (ko) 2021-07-06
US10457724B2 (en) 2019-10-29
US20190002540A1 (en) 2019-01-03
JP6506172B2 (ja) 2019-04-24
RU2661406C2 (ru) 2018-07-16
BR112015010126B1 (pt) 2022-11-01

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