BR112015010126B1 - Uso de um anticorpo anti-alfa toxina (anti-at) de s. aureus isolado - Google Patents
Uso de um anticorpo anti-alfa toxina (anti-at) de s. aureus isolado Download PDFInfo
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
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- Public Health (AREA)
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- Microbiology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US201261723128P | 2012-11-06 | 2012-11-06 | |
| US61/723,128 | 2012-11-06 | ||
| PCT/US2013/068385 WO2014074470A1 (en) | 2012-11-06 | 2013-11-05 | Methods of treating s. aureus-associated diseases |
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| BR112015010126A2 BR112015010126A2 (enExample) | 2017-08-22 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| HRP20180458T1 (hr) | 2011-06-10 | 2018-06-29 | Medimmune Limited | Molekule koje vežu anti-pseudomonas psl i njihova uporaba |
| AU2012336028A1 (en) * | 2011-11-07 | 2014-06-26 | Medimmune, Llc | Combination therapies using anti- Pseudomonas Psl and PcrV binding molecules |
| ES2776179T3 (es) * | 2012-11-06 | 2020-07-29 | Medimmune Llc | Anticuerpos dirigidos contra determinantes de la superficie de S. aureus |
| RU2661406C2 (ru) * | 2012-11-06 | 2018-07-16 | МЕДИММЬЮН, ЭлЭлСи | Способы лечения заболеваний, ассоциированных с s. aureus |
| TWI719938B (zh) | 2014-06-19 | 2021-03-01 | 美商麥迪紐有限責任公司 | 多重細菌感染之治療 |
| TW202311284A (zh) | 2017-01-03 | 2023-03-16 | 美商再生元醫藥公司 | 抗金黃色葡萄球菌溶血素ａ毒素之人類抗體 |
| WO2020023644A2 (en) | 2018-07-24 | 2020-01-30 | Medimmune, Llc | Antibody directed against s. aureus clumping factor a (clfa) |
| CN113164602A (zh) | 2018-10-09 | 2021-07-23 | 免疫医疗有限责任公司 | 抗金黄色葡萄球菌抗体的组合 |
| AU2019359207A1 (en) | 2018-10-09 | 2021-05-20 | Humabs Biomed Sa | Antibodies directed against Staphylococcus aureus leukotoxins |
| WO2020185986A1 (en) | 2019-03-13 | 2020-09-17 | Medimmune, Llc | Decreasing staphylococcus aureus infections in colonized patients |
| CN112538112B (zh) * | 2019-09-20 | 2023-10-27 | 迈威(上海)生物科技股份有限公司 | 抗α-溶血素的抗体及其应用 |
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| EP2719397A1 (en) | 2006-06-12 | 2014-04-16 | GlaxoSmithKline Biologicals SA | Use of alpha-toxin for treating and preventing staphylococcus infections |
| KR20100072228A (ko) | 2007-08-31 | 2010-06-30 | 유니버시티 오브 시카고 | 스타필로코커스 폐 질환 및 상태에 대한 면역화와 관련된 방법 및 조성물 |
| WO2011008939A2 (en) * | 2009-07-16 | 2011-01-20 | Medical College Of Georgia Research Institute, Inc. | Porous-wall hollow glass microspheres as carriers for biomolecules |
| EP2284193A1 (en) | 2009-08-10 | 2011-02-16 | Kenta Biotech AG | Human monoclonal antibody against S. aureus derived apha-toxin and its use in treating or preventing abscess formation |
| WO2012109167A1 (en) | 2011-02-08 | 2012-08-16 | Integrated Biotherapeutics, Inc. | Immunogenic composition comprising alpha-hemolysin oligopeptides |
| US9527905B2 (en) | 2011-02-08 | 2016-12-27 | Medimmune, Llc | Antibodies that specifically bind Staphylococcus aureus alpha toxin and methods of use |
| ES2776179T3 (es) | 2012-11-06 | 2020-07-29 | Medimmune Llc | Anticuerpos dirigidos contra determinantes de la superficie de S. aureus |
| RU2661406C2 (ru) * | 2012-11-06 | 2018-07-16 | МЕДИММЬЮН, ЭлЭлСи | Способы лечения заболеваний, ассоциированных с s. aureus |
| TWI719938B (zh) | 2014-06-19 | 2021-03-01 | 美商麥迪紐有限責任公司 | 多重細菌感染之治療 |
| WO2017075188A2 (en) | 2015-10-30 | 2017-05-04 | Medimmune, Llc | Methods of using anti-alpha toxin antibody |
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2013
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- 2013-11-05 WO PCT/US2013/068385 patent/WO2014074470A1/en not_active Ceased
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2017
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- 2019-10-11 US US16/599,595 patent/US10759849B2/en active Active
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