SG10201610881UA - Differentiation of primate pluripotent stem cells to hematopoietic lineage cells - Google Patents

Differentiation of primate pluripotent stem cells to hematopoietic lineage cells

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Publication number
SG10201610881UA
SG10201610881UA SG10201610881UA SG10201610881UA SG10201610881UA SG 10201610881U A SG10201610881U A SG 10201610881UA SG 10201610881U A SG10201610881U A SG 10201610881UA SG 10201610881U A SG10201610881U A SG 10201610881UA SG 10201610881U A SG10201610881U A SG 10201610881UA
Authority
SG
Singapore
Prior art keywords
cells
differentiation
pluripotent stem
hematopoietic lineage
primate pluripotent
Prior art date
Application number
SG10201610881UA
Other languages
English (en)
Inventor
Tseng Suyi
Sen Majumdar Anish
Nishimoto Kevin
Reddy Anita
Lebkowski Jane
Original Assignee
Asterias Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asterias Biotherapeutics Inc filed Critical Asterias Biotherapeutics Inc
Publication of SG10201610881UA publication Critical patent/SG10201610881UA/en

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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0639Dendritic cells, e.g. Langherhans cells in the epidermis
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/02Compounds of the arachidonic acid pathway, e.g. prostaglandins, leukotrienes
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/125Stem cell factor [SCF], c-kit ligand [KL]
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/155Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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    • C12N2501/165Vascular endothelial growth factor [VEGF]
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/24Interferons [IFN]
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/52CD40, CD40-ligand (CD154)
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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

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  • Health & Medical Sciences (AREA)
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  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
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  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG10201610881UA 2008-03-27 2009-03-26 Differentiation of primate pluripotent stem cells to hematopoietic lineage cells SG10201610881UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3983508P 2008-03-27 2008-03-27
US8124208P 2008-07-16 2008-07-16

Publications (1)

Publication Number Publication Date
SG10201610881UA true SG10201610881UA (en) 2017-03-30

Family

ID=41114730

Family Applications (2)

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SG2013050216A SG192449A1 (en) 2008-03-27 2009-03-26 Differentiation of primate pluripotent stem cells to hematopoietic lineage cells
SG10201610881UA SG10201610881UA (en) 2008-03-27 2009-03-26 Differentiation of primate pluripotent stem cells to hematopoietic lineage cells

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SG2013050216A SG192449A1 (en) 2008-03-27 2009-03-26 Differentiation of primate pluripotent stem cells to hematopoietic lineage cells

Country Status (12)

Country Link
US (3) US8093049B2 (de)
EP (2) EP3293255A1 (de)
JP (4) JP5734836B2 (de)
KR (4) KR102116658B1 (de)
CN (3) CN102016007B (de)
AU (2) AU2009228215B2 (de)
CA (2) CA3123228A1 (de)
ES (1) ES2647533T3 (de)
GB (1) GB2470689A (de)
IL (1) IL208116A (de)
SG (2) SG192449A1 (de)
WO (1) WO2009120891A2 (de)

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CN102016007B (zh) 2019-04-19
JP2015146817A (ja) 2015-08-20
EP2268794A4 (de) 2012-04-18
AU2016201540B2 (en) 2018-02-08
CN116875549A (zh) 2023-10-13
SG192449A1 (en) 2013-08-30
US20090246869A1 (en) 2009-10-01
JP5734836B2 (ja) 2015-06-17
US8093049B2 (en) 2012-01-10
CA2718438C (en) 2021-06-29
KR20160148065A (ko) 2016-12-23
AU2009228215B2 (en) 2015-12-10
JP6494677B2 (ja) 2019-04-03
KR102116658B1 (ko) 2020-06-01
GB201015471D0 (en) 2010-10-27
KR101946785B1 (ko) 2019-02-12
EP3293255A1 (de) 2018-03-14
JP2019110915A (ja) 2019-07-11
KR20200060550A (ko) 2020-05-29
JP6106705B2 (ja) 2017-04-05
JP6942746B2 (ja) 2021-09-29
US20170369842A1 (en) 2017-12-28
CN102016007A (zh) 2011-04-13
EP2268794B1 (de) 2017-09-13
AU2009228215A1 (en) 2009-10-01
GB2470689A (en) 2010-12-01
ES2647533T3 (es) 2017-12-22
IL208116A (en) 2014-06-30
US10344262B2 (en) 2019-07-09
KR101689124B1 (ko) 2016-12-23
JP2011515110A (ja) 2011-05-19
CN109988749A (zh) 2019-07-09
WO2009120891A3 (en) 2010-01-07
WO2009120891A2 (en) 2009-10-01
CN109988749B (zh) 2023-06-16
CA3123228A1 (en) 2009-10-01
EP2268794A2 (de) 2011-01-05
KR102242305B1 (ko) 2021-04-19
KR20190015618A (ko) 2019-02-13
US20120107931A1 (en) 2012-05-03
JP2017123867A (ja) 2017-07-20
IL208116A0 (en) 2010-12-30
KR20100132507A (ko) 2010-12-17
CA2718438A1 (en) 2009-10-01

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