SE9903997D0 - New compounds - Google Patents

New compounds

Info

Publication number
SE9903997D0
SE9903997D0 SE9903997A SE9903997A SE9903997D0 SE 9903997 D0 SE9903997 D0 SE 9903997D0 SE 9903997 A SE9903997 A SE 9903997A SE 9903997 A SE9903997 A SE 9903997A SE 9903997 D0 SE9903997 D0 SE 9903997D0
Authority
SE
Sweden
Prior art keywords
compounds
new compounds
nicotinic
reductions
enantiomers
Prior art date
Application number
SE9903997A
Other languages
English (en)
Swedish (sv)
Inventor
David Gurley
Thomas Lanthorn
John Macor
James Rosamond
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9903997A priority Critical patent/SE9903997D0/xx
Publication of SE9903997D0 publication Critical patent/SE9903997D0/xx
Priority to NZ518450A priority patent/NZ518450A/en
Priority to MXPA02004232A priority patent/MXPA02004232A/es
Priority to EP00976500A priority patent/EP1230216A1/en
Priority to CA002387745A priority patent/CA2387745A1/en
Priority to US10/111,027 priority patent/US6750242B1/en
Priority to NZ530161A priority patent/NZ530161A/en
Priority to PCT/SE2000/002148 priority patent/WO2001032619A1/en
Priority to CO00083175A priority patent/CO5251458A1/es
Priority to JP2001534771A priority patent/JP2003513071A/ja
Priority to KR1020027005706A priority patent/KR20020063176A/ko
Priority to IL14909800A priority patent/IL149098A0/xx
Priority to BR0015195-5A priority patent/BR0015195A/pt
Priority to CNB008154414A priority patent/CN1239482C/zh
Priority to AU14264/01A priority patent/AU783507B2/en
Priority to ZA200203171A priority patent/ZA200203171B/xx
Priority to NO20022009A priority patent/NO323076B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE9903997A 1999-11-03 1999-11-03 New compounds SE9903997D0 (sv)

Priority Applications (17)

Application Number Priority Date Filing Date Title
SE9903997A SE9903997D0 (sv) 1999-11-03 1999-11-03 New compounds
AU14264/01A AU783507B2 (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
NZ530161A NZ530161A (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
CO00083175A CO5251458A1 (es) 1999-11-03 2000-11-01 Nuevos compuestos
EP00976500A EP1230216A1 (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
CA002387745A CA2387745A1 (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
US10/111,027 US6750242B1 (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
NZ518450A NZ518450A (en) 1999-11-03 2000-11-01 Indole derivatives and their use as positive modulators of nicotinic receptor agonists
PCT/SE2000/002148 WO2001032619A1 (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
MXPA02004232A MXPA02004232A (es) 1999-11-03 2000-11-01 Moduladores positivos de agonistas de receptores nicotinicos.
JP2001534771A JP2003513071A (ja) 1999-11-03 2000-11-01 ニコチン受容体作用薬の正のモジュレーター
KR1020027005706A KR20020063176A (ko) 1999-11-03 2000-11-01 니코틴 수용체 작용물질의 양성 조절자
IL14909800A IL149098A0 (en) 1999-11-03 2000-11-01 Positive modulators of nicotinic receptor agonists
BR0015195-5A BR0015195A (pt) 1999-11-03 2000-11-01 Composto, composição farmacêutica, uso de um composto, e, métodos para o tratamento de uma condição associada com a transmissão reduzida de nicotina para o tratamento ou profilaxia de distúrbios psicóticos ou distúrbios de deterioração intelectual e para o tratamento ou profilaxia de doenças ou condições humanas
CNB008154414A CN1239482C (zh) 1999-11-03 2000-11-01 烟碱性受体激动剂的正调节剂
ZA200203171A ZA200203171B (en) 1999-11-03 2002-04-22 Positive modulators of nicotinic receptor agonists.
NO20022009A NO323076B1 (no) 1999-11-03 2002-04-26 Forbindelser, preparater, nevnte forbindelser og preparater for bruk i terapi samt anvendelse av nevnte forbindelser for fremstilling av preparater til medisinsk behandling.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9903997A SE9903997D0 (sv) 1999-11-03 1999-11-03 New compounds

Publications (1)

Publication Number Publication Date
SE9903997D0 true SE9903997D0 (sv) 1999-11-03

Family

ID=20417607

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9903997A SE9903997D0 (sv) 1999-11-03 1999-11-03 New compounds

Country Status (16)

Country Link
US (1) US6750242B1 (enExample)
EP (1) EP1230216A1 (enExample)
JP (1) JP2003513071A (enExample)
KR (1) KR20020063176A (enExample)
CN (1) CN1239482C (enExample)
AU (1) AU783507B2 (enExample)
BR (1) BR0015195A (enExample)
CA (1) CA2387745A1 (enExample)
CO (1) CO5251458A1 (enExample)
IL (1) IL149098A0 (enExample)
MX (1) MXPA02004232A (enExample)
NO (1) NO323076B1 (enExample)
NZ (2) NZ518450A (enExample)
SE (1) SE9903997D0 (enExample)
WO (1) WO2001032619A1 (enExample)
ZA (1) ZA200203171B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903998D0 (sv) * 1999-11-03 1999-11-03 Astra Ab New compounds
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
DE10234424A1 (de) * 2002-07-29 2004-02-12 Bayer Ag Benzothiophen-, Benzofuran- und Indolharnstoffe
JP2006501246A (ja) 2002-08-30 2006-01-12 メモリー・ファーマシューティカルズ・コーポレイション 神経変性疾患の治療において有用なアナバセイン誘導体
AU2003276919B2 (en) 2002-09-25 2013-05-16 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof
US20050234095A1 (en) 2004-03-25 2005-10-20 Wenge Xie Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
CN101247853B (zh) * 2005-04-13 2014-11-12 轴突公司 具有nos抑制活性的取代的吲哚化合物
US20070134169A1 (en) * 2005-12-11 2007-06-14 Rabinoff Michael D Methods for smoking cessation or alcohol cessation or other addiction cessation
US7989447B2 (en) 2006-04-13 2011-08-02 Neuraxon, Inc. 1,5 and 3,6-substituted indole compounds having NOS inhibitory activity
AU2008321353A1 (en) * 2007-11-16 2009-05-22 The Arizona Board Of Regents On Behalf Of The University Of Arizona Methods for treating visceral pain
MX2010005343A (es) * 2007-11-16 2010-08-09 Neuraxon Inc Compuestos indola 3, 5-sustituidos que tienen actividad inhibidora de la re-absorcion y el reciclo de nos y norepinefrina.
JP2011503120A (ja) * 2007-11-16 2011-01-27 ニューラクソン，インコーポレーテッド 内臓痛を治療するためのインドール化合物および方法
US8383657B2 (en) 2007-12-21 2013-02-26 Abbott Laboratories Thiazolylidine urea and amide derivatives and methods of use thereof
AU2009212259A1 (en) * 2008-02-07 2009-08-13 Abbott Laboratories Amide derivatives as positive allosteric modulators and methods of use thereof
UY31769A1 (es) 2008-04-17 2009-09-30 Derivados del indol con actividad modulatoria del receptor nicotínico de acetilcolina
JP5642154B2 (ja) * 2009-04-16 2014-12-17 プロキシマジェン エルティーディーＰｒｏｘｉｍａｇｅｎ Ｌｔｄ． α７ｎＡＣｈＲのインドール誘導体モジュレータ
JP5749797B2 (ja) * 2010-05-17 2015-07-15 フォルム ファーマシューティカルズ、インコーポレイテッド （ｒ）−７−クロロ−ｎ−（キヌクリジン−３−イル）ベンゾ［ｂ］チオフェン−２−カルボキサミド塩酸塩一水和物の結晶形
TW201245185A (en) 2011-04-01 2012-11-16 Lundbeck & Co As H New positive allosteric modulators of nicotinic acetylcholine receptor
AR086791A1 (es) 2011-07-01 2014-01-22 Lundbeck & Co As H Moduladores alostericos positivos del receptor de acetilcolina nicotinico
CA2872005A1 (en) 2012-05-08 2013-11-14 Forum Pharmaceuticals, Inc. Methods of maintaining, treating or improving cognitive function
WO2020045982A1 (ko) * 2018-08-29 2020-03-05 숙명여자대학교산학협력단 치환된 인돌 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 PPARα, PPARγ 및 PPARδ 관련 질환의 예방 또는 치료용 약학적 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2787551A (en) * 1954-02-24 1957-04-02 Eastman Kodak Co Compositions stabilized with hydroxyindole
BE758766A (fr) * 1969-11-17 1971-05-10 Ici Ltd Nouveaux derives de la morpholine et de la
US4704390A (en) * 1986-02-13 1987-11-03 Warner-Lambert Company Phenyl and heterocyclic tetrahydropyridyl alkoxy-benzheterocyclic compounds as antipsychotic agents
KR930702334A (ko) * 1990-09-13 1993-09-08 데이비드 로버트 5 하이드록시트립타민 수용체 길항제로서의 인돌우레아
RU2126399C1 (ru) * 1991-11-25 1999-02-20 Пфайзер Инк. Производные индола, замещенные индолы и способ ингибирования 5ht1 рецептора серотонина
WO1993018026A1 (en) * 1992-03-04 1993-09-16 Beecham Group Plc Indole ureas as 5-ht1c receptor antogonists
US5504101A (en) * 1994-05-06 1996-04-02 Allelix Biopharmaceuticals, Inc. 5-HT-1D receptor ligands
FR2722686B1 (fr) * 1994-07-22 1996-08-30 Oreal Set, procede, dispositif et composition de teinture des fibres keratiniques
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems

Also Published As

Publication number Publication date
IL149098A0 (en) 2002-11-10
BR0015195A (pt) 2002-06-18
ZA200203171B (en) 2003-09-23
CN1239482C (zh) 2006-02-01
WO2001032619A1 (en) 2001-05-10
NO323076B1 (no) 2006-12-27
CO5251458A1 (es) 2003-02-28
MXPA02004232A (es) 2002-10-17
AU783507B2 (en) 2005-11-03
NO20022009D0 (no) 2002-04-26
AU1426401A (en) 2001-05-14
KR20020063176A (ko) 2002-08-01
US6750242B1 (en) 2004-06-15
NZ530161A (en) 2005-08-26
NZ518450A (en) 2004-04-30
CN1387512A (zh) 2002-12-25
EP1230216A1 (en) 2002-08-14
CA2387745A1 (en) 2001-05-10
NO20022009L (no) 2002-07-02
JP2003513071A (ja) 2003-04-08

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