SE9801474D0 - Quinoline Derivatives - Google Patents
Quinoline DerivativesInfo
- Publication number
- SE9801474D0 SE9801474D0 SE9801474A SE9801474A SE9801474D0 SE 9801474 D0 SE9801474 D0 SE 9801474D0 SE 9801474 A SE9801474 A SE 9801474A SE 9801474 A SE9801474 A SE 9801474A SE 9801474 D0 SE9801474 D0 SE 9801474D0
- Authority
- SE
- Sweden
- Prior art keywords
- propyl
- iso
- butyl
- formula
- ethyl
- Prior art date
Links
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 241000124008 Mammalia Species 0.000 abstract 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- -1 methoxy, ethoxy Chemical group 0.000 abstract 2
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 150000001767 cationic compounds Chemical class 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000002892 organic cations Chemical class 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (35)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9801474A SE9801474D0 (sv) | 1998-04-27 | 1998-04-27 | Quinoline Derivatives |
| US09/296,519 US6077851A (en) | 1998-04-27 | 1999-04-22 | Quinoline derivatives |
| HR20000726A HRP20000726B1 (hr) | 1998-04-27 | 1999-04-26 | Derivati kinolina |
| DE69904162T DE69904162T2 (de) | 1998-04-27 | 1999-04-26 | Chinolinderivate |
| IL13816099A IL138160A0 (en) | 1998-04-27 | 1999-04-26 | Quinoline derivatives |
| AU43013/99A AU747550B2 (en) | 1998-04-27 | 1999-04-26 | Quinoline derivatives |
| NZ506641A NZ506641A (en) | 1998-04-27 | 1999-04-26 | Quinoline derivatives useful in the treatment of autoimmune disorders |
| CZ20003849A CZ297439B6 (cs) | 1998-04-27 | 1999-04-26 | Deriváty chinolinu |
| BRPI9909925-0A BR9909925B1 (pt) | 1998-04-27 | 1999-04-26 | derivados de quinolina, composições farmacêuticas, e, processo para a fabricação de derivados de quinolina. |
| PL99343420A PL190441B1 (pl) | 1998-04-27 | 1999-04-26 | Nowe pochodne 1-metylo-2-okso-chinolino-3-karboksyamidu zawierające je kompozycje farmaceutyczne oraz sposób ich wytwarzania |
| AT99947036T ATE228505T1 (de) | 1998-04-27 | 1999-04-26 | Chinolinderivate |
| OA1200000301A OA11547A (en) | 1998-04-27 | 1999-04-26 | Quinoline derivatives. |
| UA2000085078A UA60354C2 (uk) | 1998-04-27 | 1999-04-26 | Похідні хіноліну, спосіб їх одержання (варіанти) та спосіб лікування ссавців |
| DK99947036T DK1073639T3 (da) | 1998-04-27 | 1999-04-26 | Chinolinderivater |
| APAP/P/2000/001933A AP1293A (en) | 1998-04-27 | 1999-04-26 | Quinoline derivatives. |
| CA002329788A CA2329788C (en) | 1998-04-27 | 1999-04-26 | Quinoline derivatives |
| MEP-2000-612A ME00870B (me) | 1998-04-27 | 1999-04-26 | Derivati hinolina |
| RU2000129672/04A RU2197481C2 (ru) | 1998-04-27 | 1999-04-26 | Производные хинолина |
| ES99947036T ES2188242T3 (es) | 1998-04-27 | 1999-04-26 | Derivados de quinolina. |
| EEP200000613A EE04275B1 (et) | 1998-04-27 | 1999-04-26 | Kinoliini derivaadid, nende valmistamismeetodid, kasutamine ja farmatseutilised kompositsioonid |
| TR2000/03061T TR200003061T2 (tr) | 1998-04-27 | 1999-04-26 | Kinolin türevleri |
| KR1020007011944A KR100571534B1 (ko) | 1998-04-27 | 1999-04-26 | 퀴놀린 유도체 |
| CN99805581A CN1113057C (zh) | 1998-04-27 | 1999-04-26 | 喹啉衍生物 |
| HK01105489.6A HK1036618B (en) | 1998-04-27 | 1999-04-26 | Quinoline derivatives |
| HU0102084A HU227709B1 (en) | 1998-04-27 | 1999-04-26 | Quinoline derivatives, process for producing them and pharmaceutical compositions containing them |
| PT99947036T PT1073639E (pt) | 1998-04-27 | 1999-04-26 | Derivados de quinolina |
| EP99947036A EP1073639B1 (en) | 1998-04-27 | 1999-04-26 | Quinoline derivatives |
| PCT/SE1999/000676 WO1999055678A1 (en) | 1998-04-27 | 1999-04-26 | Quinoline derivatives |
| JP2000545838A JP4045069B2 (ja) | 1998-04-27 | 1999-04-26 | キノリン誘導体 |
| YUP-612/00A RS50029B (sr) | 1998-04-27 | 1999-04-26 | Derivati hinolina |
| IDW20002183A ID26277A (id) | 1998-04-27 | 1999-04-26 | Turunan-turunan kuinolina |
| IL138160A IL138160A (en) | 1998-04-27 | 2000-08-30 | Quinoline derivatives |
| IS5615A IS2082B (is) | 1998-04-27 | 2000-08-31 | Kvínólínafleiður |
| ZA200004601A ZA200004601B (en) | 1998-04-27 | 2000-09-01 | Quinoline derivatives. |
| NO20005254A NO315606B1 (no) | 1998-04-27 | 2000-10-19 | Kinolinderivater |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9801474A SE9801474D0 (sv) | 1998-04-27 | 1998-04-27 | Quinoline Derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE9801474D0 true SE9801474D0 (sv) | 1998-04-27 |
Family
ID=20411103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9801474A SE9801474D0 (sv) | 1998-04-27 | 1998-04-27 | Quinoline Derivatives |
Country Status (32)
| Country | Link |
|---|---|
| EP (1) | EP1073639B1 (cs) |
| JP (1) | JP4045069B2 (cs) |
| KR (1) | KR100571534B1 (cs) |
| CN (1) | CN1113057C (cs) |
| AP (1) | AP1293A (cs) |
| AT (1) | ATE228505T1 (cs) |
| AU (1) | AU747550B2 (cs) |
| BR (1) | BR9909925B1 (cs) |
| CA (1) | CA2329788C (cs) |
| CZ (1) | CZ297439B6 (cs) |
| DE (1) | DE69904162T2 (cs) |
| DK (1) | DK1073639T3 (cs) |
| EE (1) | EE04275B1 (cs) |
| ES (1) | ES2188242T3 (cs) |
| HR (1) | HRP20000726B1 (cs) |
| HU (1) | HU227709B1 (cs) |
| ID (1) | ID26277A (cs) |
| IL (2) | IL138160A0 (cs) |
| IS (1) | IS2082B (cs) |
| ME (1) | ME00870B (cs) |
| NO (1) | NO315606B1 (cs) |
| NZ (1) | NZ506641A (cs) |
| OA (1) | OA11547A (cs) |
| PL (1) | PL190441B1 (cs) |
| PT (1) | PT1073639E (cs) |
| RS (1) | RS50029B (cs) |
| RU (1) | RU2197481C2 (cs) |
| SE (1) | SE9801474D0 (cs) |
| TR (1) | TR200003061T2 (cs) |
| UA (1) | UA60354C2 (cs) |
| WO (1) | WO1999055678A1 (cs) |
| ZA (1) | ZA200004601B (cs) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0002320D0 (sv) * | 1999-10-25 | 2000-06-21 | Active Biotech Ab | Malignant tumors |
| SE0201778D0 (sv) * | 2002-06-12 | 2002-06-12 | Active Biotech Ab | Process for the manufacture of quinoline derivatives |
| KR100908655B1 (ko) | 2002-11-27 | 2009-07-21 | 엘지디스플레이 주식회사 | 데이터 공급시간의 변조방법과 이를 이용한액정표시장치의 구동방법 및 장치 |
| SE0400235D0 (sv) * | 2004-02-06 | 2004-02-06 | Active Biotech Ab | New composition containing quinoline compounds |
| SE0401578D0 (sv) * | 2004-06-18 | 2004-06-18 | Active Biotech Ab | Novel compounds |
| US7838522B2 (en) | 2004-11-17 | 2010-11-23 | Ares Trading S.A. | Benzothiazole formulations and use thereof |
| WO2006067114A1 (en) | 2004-12-21 | 2006-06-29 | Laboratoires Serono S.A. | Sulfonyl amino cyclic derivatives and use thereof |
| MX2007009231A (es) | 2005-01-31 | 2007-09-19 | Serono Lab | Derivados de n-hidroxiamida y uso de los mismos. |
| BRPI0613042A2 (pt) | 2005-07-15 | 2010-12-14 | Serono Lab | inibidores de jnk para o tratamento de endometriose |
| KR20080044836A (ko) | 2005-07-15 | 2008-05-21 | 라보라뚜와르 세로노 에스. 에이. | 자궁내막증 치료용 ｊｎｋ 억제제 |
| US8178083B2 (en) | 2005-09-01 | 2012-05-15 | Ares Trading, S.A. | Treatment of optic neuritis |
| EP1937642B1 (en) * | 2005-10-19 | 2014-09-10 | Teva Pharmaceutical Industries Ltd | Crystals of laquinimod sodium, and process for the manufacture thereof |
| AR061348A1 (es) | 2006-06-12 | 2008-08-20 | Teva Pharma | Preparados estables de laquinimod |
| PL2234485T3 (pl) | 2007-12-20 | 2014-06-30 | Teva Pharma | Stabilne preparaty lakwinimodu |
| BRPI0913518A2 (pt) * | 2008-09-03 | 2016-07-26 | Teva Pharma | composto, composição farmacêutica, e, método de tratamento de um distúrbio mediado por função imune |
| US8598203B2 (en) * | 2009-07-30 | 2013-12-03 | Teva Pharmaceutical Industries, Ltd. | Treatment of Crohn's disease with laquinimod |
| SI2467372T1 (sl) | 2009-08-10 | 2016-09-30 | Teva Pharmaceutical Industries Ltd. | Zdravljenje motenj, povezanih z BDNF, z uporabo lakvinimoda |
| AU2011223702B2 (en) * | 2010-03-03 | 2016-07-14 | Teva Pharmaceutical Industries Ltd. | Treatment of lupus arthritis using laquinimod |
| SI2542079T1 (sl) | 2010-03-03 | 2014-08-29 | Teva Pharmaceutical Industries Ltd. | Zdravljenje revmatoidnega artritisa s kombinacijo lakvinimoda in metotreksata |
| PH12012501739A1 (en) * | 2010-03-03 | 2017-08-23 | Teva Pharma | Treatment of lupus nephritis using laquinimod |
| WO2011116091A1 (en) | 2010-03-17 | 2011-09-22 | Novartis Ag | Dispenser |
| MX2013000333A (es) | 2010-07-09 | 2013-02-26 | Teva Pharma | N-etil-n-fenil-1,2-dihidro-4-hidroxi-5-cloro-1-metil-2-oxoquinoli na-3-carboxamida deuterada, sales y usos de la misma. |
| BR112012033465A2 (pt) | 2010-07-09 | 2017-06-20 | Active Biotech Ab | método para preparar um composto |
| BR112013000607A2 (pt) * | 2010-07-09 | 2016-06-28 | Teva Pharma | 5-cloro-4-hidroxi-1-metil-2-oxo-n-fenil-1,2-di-hidroquinolina-3-carboxamida, os sais e suas utilizações |
| EP2444086A1 (en) | 2010-10-22 | 2012-04-25 | Almirall, S.A. | Combinations comprising DHODH inhibitors and COX inhibitors |
| MX2014004420A (es) | 2011-10-12 | 2014-07-09 | Teva Pharma | Tratamiento de esclerosis multiple con combinacion de laquinimod y fingolimod. |
| US9161935B2 (en) * | 2012-02-03 | 2015-10-20 | Teva Pharmaceutical Industries, Ltd. | Use of laquinimod for treating Crohn's disease patients who failed first-line anti-TNF therapy |
| SG11201404419WA (en) | 2012-02-16 | 2014-10-30 | Teva Pharma | N-ethyl-n-phenyl-1,2-dihydro-4,5-di-hydroxy-1-methyl-2-oxo-3-quinoline carboxamide, preparation and uses thereof |
| TW201350467A (zh) | 2012-05-08 | 2013-12-16 | Teva Pharma | Ｎ－乙基－４－羥基－１－甲基－５－（甲基（２，３，４，５，６－五羥基己基）胺基）－２－側氧－ｎ－苯基－１，２－二氫喹啉－３－甲醯胺 |
| TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
| TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療ｇａｂａ媒介之疾病之拉喹莫德（ｌａｑｕｉｎｉｍｏｄ） |
| KR20150091077A (ko) | 2012-11-07 | 2015-08-07 | 테바 파마슈티컬 인더스트리즈 리미티드 | 라퀴니모드의 아민염 |
| RU2545056C2 (ru) * | 2012-12-10 | 2015-03-27 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия" Министерства здавоохранения и социального развития Российской Федерации (ГБОУ ВПО ПГФА Минздравсоцразвития России) | Противовоспалительное и анальгетическое средство на основе изопропиламида 1,2-дигидро-1н-2-оксоцинхониновой кислоты |
| US20140235670A1 (en) * | 2013-02-15 | 2014-08-21 | Teva Pharmaceutical Industries, Ltd. | Treatment of progressive forms of multiple sclerosis with laquinimod |
| US20160046582A1 (en) | 2013-03-14 | 2016-02-18 | Teva Pharmaceutical Industries Ltd. | Crystals of laquinimod sodium and improved process for the manufacture thereof |
| WO2015168103A1 (en) | 2014-04-29 | 2015-11-05 | Teva Pharmaceutical Industries Ltd. | Laquinimod for the treatment of relapsing-remitting multiple sclerosis (rrms) patients with a high disability status |
| MX366837B (es) | 2014-09-23 | 2019-07-26 | Active Biotech Ab | Quinolinas carboxamidas para usarse en el tratamiento de mielomas multiples. |
| EA031643B1 (ru) | 2014-11-19 | 2019-01-31 | Эктив Байотек Аб | Применение тасквинимода для лечения острого лимфобластного лейкоза и острого миелоидного лейкоза |
| JP7730816B2 (ja) | 2019-12-19 | 2025-08-28 | アクティブ バイオテック エービー | 過剰血管新生に関連する眼疾患を治療する化合物 |
| BR112022016873A2 (pt) | 2020-03-03 | 2022-10-25 | Active Biotech Ab | Combinação, kit, e, tasquinimod ou um sal farmaceuticamente aceitável do mesmo para uso no tratamento de mieloma múltiplo |
| CA3179303A1 (en) * | 2020-05-21 | 2021-11-25 | Darren Orton | Notch inhibitors and uses thereof |
| ES3037361T3 (en) | 2020-07-23 | 2025-10-01 | Univ Erasmus Med Ct Rotterdam | S100 proteins as novel therapeutic targets in myeloproliferative neoplasms |
| EP4277628B1 (en) | 2021-01-18 | 2025-09-24 | Active Biotech AB | Tasquinimod or a pharmaceutically acceptable salt thereof for use in the treatment of myelodysplastic syndrome |
| IL308542A (en) | 2021-05-25 | 2024-01-01 | Active Biotech Ab | Multiparticles of tesquinimod and their use |
| JP2024524158A (ja) | 2021-07-02 | 2024-07-05 | アクティブ バイオテック エイビー | タスキニモドを含有する医薬製品および前記製品の純度を評価する方法 |
| WO2025083549A1 (en) | 2023-10-16 | 2025-04-24 | Sun Pharma Advanced Research Company Limited | Methods and combinations of inhibitors of il-23 pathway and modulators of s1p signaling pathway for the treatment of autoimmune disorders |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE52670B1 (en) * | 1981-03-03 | 1988-01-20 | Leo Ab | Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation |
| SU1735288A1 (ru) * | 1990-03-05 | 1992-05-23 | Харьковский государственный фармацевтический институт | Способ получени N-R-замещенных амидов 4-гидроксихинолон-2 карбоновой -3-кислоты |
| GB9108547D0 (en) * | 1991-04-22 | 1991-06-05 | Fujisawa Pharmaceutical Co | Quinoline derivatives |
| DE4120646A1 (de) * | 1991-06-22 | 1992-12-24 | Bayer Ag | 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate |
| US5428040A (en) * | 1993-08-31 | 1995-06-27 | The Du Pont Merck Pharmaceutical Company | Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents |
| SE9400810D0 (sv) * | 1994-03-10 | 1994-03-10 | Pharmacia Ab | New use of Quinoline-3-carboxamide compounds |
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1998
- 1998-04-27 SE SE9801474A patent/SE9801474D0/xx unknown
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1999
- 1999-04-26 IL IL13816099A patent/IL138160A0/xx active IP Right Grant
- 1999-04-26 TR TR2000/03061T patent/TR200003061T2/xx unknown
- 1999-04-26 HR HR20000726A patent/HRP20000726B1/xx not_active IP Right Cessation
- 1999-04-26 CZ CZ20003849A patent/CZ297439B6/cs not_active IP Right Cessation
- 1999-04-26 RS YUP-612/00A patent/RS50029B/sr unknown
- 1999-04-26 UA UA2000085078A patent/UA60354C2/uk unknown
- 1999-04-26 PL PL99343420A patent/PL190441B1/pl unknown
- 1999-04-26 WO PCT/SE1999/000676 patent/WO1999055678A1/en not_active Ceased
- 1999-04-26 DE DE69904162T patent/DE69904162T2/de not_active Expired - Lifetime
- 1999-04-26 BR BRPI9909925-0A patent/BR9909925B1/pt not_active IP Right Cessation
- 1999-04-26 ES ES99947036T patent/ES2188242T3/es not_active Expired - Lifetime
- 1999-04-26 AT AT99947036T patent/ATE228505T1/de active
- 1999-04-26 AP APAP/P/2000/001933A patent/AP1293A/en active
- 1999-04-26 AU AU43013/99A patent/AU747550B2/en not_active Ceased
- 1999-04-26 ID IDW20002183A patent/ID26277A/id unknown
- 1999-04-26 RU RU2000129672/04A patent/RU2197481C2/ru not_active IP Right Cessation
- 1999-04-26 EP EP99947036A patent/EP1073639B1/en not_active Expired - Lifetime
- 1999-04-26 ME MEP-2000-612A patent/ME00870B/me unknown
- 1999-04-26 EE EEP200000613A patent/EE04275B1/xx unknown
- 1999-04-26 PT PT99947036T patent/PT1073639E/pt unknown
- 1999-04-26 OA OA1200000301A patent/OA11547A/en unknown
- 1999-04-26 CN CN99805581A patent/CN1113057C/zh not_active Expired - Fee Related
- 1999-04-26 NZ NZ506641A patent/NZ506641A/en not_active IP Right Cessation
- 1999-04-26 HU HU0102084A patent/HU227709B1/hu not_active IP Right Cessation
- 1999-04-26 DK DK99947036T patent/DK1073639T3/da active
- 1999-04-26 CA CA002329788A patent/CA2329788C/en not_active Expired - Fee Related
- 1999-04-26 JP JP2000545838A patent/JP4045069B2/ja not_active Expired - Lifetime
- 1999-04-26 KR KR1020007011944A patent/KR100571534B1/ko not_active Expired - Fee Related
-
2000
- 2000-08-30 IL IL138160A patent/IL138160A/en not_active IP Right Cessation
- 2000-08-31 IS IS5615A patent/IS2082B/is unknown
- 2000-09-01 ZA ZA200004601A patent/ZA200004601B/en unknown
- 2000-10-19 NO NO20005254A patent/NO315606B1/no not_active IP Right Cessation
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