SE9702772D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE9702772D0
SE9702772D0 SE9702772A SE9702772A SE9702772D0 SE 9702772 D0 SE9702772 D0 SE 9702772D0 SE 9702772 A SE9702772 A SE 9702772A SE 9702772 A SE9702772 A SE 9702772A SE 9702772 D0 SE9702772 D0 SE 9702772D0
Authority
SE
Sweden
Prior art keywords
pct
novel compounds
sec
date
pub
Prior art date
Application number
SE9702772A
Other languages
English (en)
Swedish (sv)
Inventor
David Hardern
Brian Springthorpe
Original Assignee
Astra Pharma Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod
Priority to SE9702772A priority Critical patent/SE9702772D0/xx
Publication of SE9702772D0 publication Critical patent/SE9702772D0/xx
Priority to IDW20000146A priority patent/ID24837A/id
Priority to EP98934106A priority patent/EP0996620B1/en
Priority to PCT/SE1998/001392 priority patent/WO1999005142A1/en
Priority to CN98809135A priority patent/CN1271359A/zh
Priority to DE69804964T priority patent/DE69804964T2/de
Priority to AT98934106T priority patent/ATE216389T1/de
Priority to JP2000504138A priority patent/JP2001510841A/ja
Priority to IL13411298A priority patent/IL134112A0/xx
Priority to SK1880-99A priority patent/SK188099A3/sk
Priority to EEP200000042A priority patent/EE200000042A/xx
Priority to KR1020007000651A priority patent/KR20010022082A/ko
Priority to CA002296648A priority patent/CA2296648A1/en
Priority to PL98338518A priority patent/PL338518A1/xx
Priority to TR2000/00151T priority patent/TR200000151T2/xx
Priority to AU83705/98A priority patent/AU8370598A/en
Priority to HU0100202A priority patent/HUP0100202A3/hu
Priority to BR9811022-5A priority patent/BR9811022A/pt
Priority to US09/155,562 priority patent/US6156756A/en
Priority to IS5351A priority patent/IS5351A/is
Priority to NO20000311A priority patent/NO20000311L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Use Of Switch Circuits For Exchanges And Methods Of Control Of Multiplex Exchanges (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE9702772A 1997-07-22 1997-07-22 Novel compounds SE9702772D0 (sv)

Priority Applications (21)

Application Number Priority Date Filing Date Title
SE9702772A SE9702772D0 (sv) 1997-07-22 1997-07-22 Novel compounds
IDW20000146A ID24837A (id) 1997-07-22 1997-07-24 Senyawa triazolo [4,5-d] pirimidina, penggunaan, komposisi dan proses pembuatannya
US09/155,562 US6156756A (en) 1997-07-22 1998-07-15 Triazolo [4,5-d]pyrimidine compounds, their use as medicaments, compositions containing them and processes for their preparation
IL13411298A IL134112A0 (en) 1997-07-22 1998-07-15 Triazolo [4,5-d] pyrimidine compounds, their use anovel compounds s medicaments, compositions containing them and processes for their preparation
KR1020007000651A KR20010022082A (ko) 1997-07-22 1998-07-15 신규 화합물
CN98809135A CN1271359A (zh) 1997-07-22 1998-07-15 新的化合物
DE69804964T DE69804964T2 (de) 1997-07-22 1998-07-15 Neue verbindungen
AT98934106T ATE216389T1 (de) 1997-07-22 1998-07-15 Neue verbindungen
JP2000504138A JP2001510841A (ja) 1997-07-22 1998-07-15 新規な化合物
EP98934106A EP0996620B1 (en) 1997-07-22 1998-07-15 Novel compounds
SK1880-99A SK188099A3 (en) 1997-07-22 1998-07-15 Triazolo[4,5-d]pyrimidine compounds, preparation thereof, pharmaceutical compositions containing them and their use
EEP200000042A EE200000042A (et) 1997-07-22 1998-07-15 Uued ühendid
PCT/SE1998/001392 WO1999005142A1 (en) 1997-07-22 1998-07-15 Novel compounds
CA002296648A CA2296648A1 (en) 1997-07-22 1998-07-15 Novel compounds
PL98338518A PL338518A1 (en) 1997-07-22 1998-07-15 Novel compounds
TR2000/00151T TR200000151T2 (tr) 1997-07-22 1998-07-15 Yeni bileşimler.
AU83705/98A AU8370598A (en) 1997-07-22 1998-07-15 Novel compounds
HU0100202A HUP0100202A3 (en) 1997-07-22 1998-07-15 Novel triazolo[4,5-d]pyrimidine derivatives, process for their preparation, their use and pharmaceutical compositions containing them
BR9811022-5A BR9811022A (pt) 1997-07-22 1998-07-15 Composto, composição farmacêutica, e, processo para preparação de um composto
IS5351A IS5351A (is) 1997-07-22 2000-01-19 Ný efnasambönd
NO20000311A NO20000311L (no) 1997-07-22 2000-01-21 Nye forbindelser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9702772A SE9702772D0 (sv) 1997-07-22 1997-07-22 Novel compounds

Publications (1)

Publication Number Publication Date
SE9702772D0 true SE9702772D0 (sv) 1997-07-22

Family

ID=20407803

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9702772A SE9702772D0 (sv) 1997-07-22 1997-07-22 Novel compounds

Country Status (21)

Country Link
US (1) US6156756A (no)
EP (1) EP0996620B1 (no)
JP (1) JP2001510841A (no)
KR (1) KR20010022082A (no)
CN (1) CN1271359A (no)
AT (1) ATE216389T1 (no)
AU (1) AU8370598A (no)
BR (1) BR9811022A (no)
CA (1) CA2296648A1 (no)
DE (1) DE69804964T2 (no)
EE (1) EE200000042A (no)
HU (1) HUP0100202A3 (no)
ID (1) ID24837A (no)
IL (1) IL134112A0 (no)
IS (1) IS5351A (no)
NO (1) NO20000311L (no)
PL (1) PL338518A1 (no)
SE (1) SE9702772D0 (no)
SK (1) SK188099A3 (no)
TR (1) TR200000151T2 (no)
WO (1) WO1999005142A1 (no)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
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SE9702773D0 (sv) * 1997-07-22 1997-07-22 Astra Pharma Prod Novel compounds
JP2002503663A (ja) * 1998-02-17 2002-02-05 アストラゼネカ ユーケイ リミテッド 新規のトリアゾロ（４，５−ｄ）ピリミジン化合物
SE9802574D0 (sv) * 1998-07-17 1998-07-17 Astra Pharma Prod Novel compounds
TWI229674B (en) * 1998-12-04 2005-03-21 Astra Pharma Prod Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
SE9904129D0 (sv) * 1999-11-15 1999-11-15 Astra Pharma Prod Novel compounds
SE9904128D0 (sv) * 1999-11-15 1999-11-15 Astra Pharma Prod Novel compounds
US6867199B2 (en) 2000-08-21 2005-03-15 Inspire Pharmaceuticals, Inc. Dinucleoside polyphosphate compositions and their therapeutic use
US7335648B2 (en) 2003-10-21 2008-02-26 Inspire Pharmaceuticals, Inc. Non-nucleotide composition and method for inhibiting platelet aggregation
US7749981B2 (en) 2003-10-21 2010-07-06 Inspire Pharmaceuticals, Inc. Drug-eluting stents coated with non-nucleotide P2Y12 receptor antagonist compound
EP1685135B1 (en) 2003-10-21 2010-05-26 Inspire Pharmaceuticals, Inc. TETRAHYDRO-FURO[3,4-d]DIOXOLE COMPOUNDS AND COMPOSITIONS AND METHOD FOR INHIBITING PLATELET AGGREGATION
US7504497B2 (en) 2003-10-21 2009-03-17 Inspire Pharmaceuticals, Inc. Orally bioavailable compounds and methods for inhibiting platelet aggregation
US7932376B2 (en) 2005-05-05 2011-04-26 Inspire Pharmaceuticals, Inc. Pyrimidine-based non-nucleotide composition and method for inhibiting platelet aggregation
WO2008054795A2 (en) * 2006-10-31 2008-05-08 Janssen Pharmaceutica, N.V. Triazolopyrimidine derivatives as adp p2y12 receptor antagonists
US8148385B2 (en) 2006-10-31 2012-04-03 Janssen Pharmaceutica N.V. Substituted [1,2,3] triazolo[4,5-d]pyrimidine derivatives as ADP P2Y12 receptor antagonists
TWI496776B (zh) * 2007-11-15 2015-08-21 Astrazeneca Ab 製備(3aR,4S,6R,6aS)-6-胺基-2,2-二甲基四氫-3aH-環戊并[d][1,3]二氧雜環戊烯-4-醇之純非對映異構性之二苯甲醯-L-酒石酸鹽之方法
EP2361242B1 (en) 2008-10-17 2018-08-01 Oryzon Genomics, S.A. Oxidase inhibitors and their use
US8993808B2 (en) 2009-01-21 2015-03-31 Oryzon Genomics, S.A. Phenylcyclopropylamine derivatives and their medical use
WO2011017108A2 (en) 2009-07-27 2011-02-10 Auspex Pharmaceuticals, Inc. Cyclopropyl modulators of p2y12 receptor
CA2812683C (en) 2009-09-25 2017-10-10 Oryzon Genomics S.A. Lysine specific demethylase-1 inhibitors and their use
WO2011042217A1 (en) 2009-10-09 2011-04-14 Oryzon Genomics S.A. Substituted heteroaryl- and aryl- cyclopropylamine acetamides and their use
WO2011101740A1 (en) * 2010-02-16 2011-08-25 Actavis Group Ptc Ehf Improved processes for preparing ticagrelor intermediate, 4,6-dichloro-5-nitro-2-(propylthio)pyrimidine
US9186337B2 (en) 2010-02-24 2015-11-17 Oryzon Genomics S.A. Lysine demethylase inhibitors for diseases and disorders associated with Hepadnaviridae
WO2011106574A2 (en) 2010-02-24 2011-09-01 Oryzon Genomics, S.A. Inhibitors for antiviral use
CN102947265B (zh) 2010-04-19 2015-07-29 奥瑞泽恩基因组学股份有限公司 赖氨酸特异性脱甲基酶-1抑制剂及其应用
WO2012013728A1 (en) 2010-07-29 2012-02-02 Oryzon Genomics S.A. Arylcyclopropylamine based demethylase inhibitors of lsd1 and their medical use
US9006449B2 (en) 2010-07-29 2015-04-14 Oryzon Genomics, S.A. Cyclopropylamine derivatives useful as LSD1 inhibitors
US9061966B2 (en) 2010-10-08 2015-06-23 Oryzon Genomics S.A. Cyclopropylamine inhibitors of oxidases
WO2012063126A2 (en) 2010-11-09 2012-05-18 Actavis Group Ptc Ehf Improved processes for preparing pure (3ar,4s,6r,6as)-6-amino-2,2-dimethyltetrahdro-3ah-cyclopenta[d] [1,3]-dioxol-4-ol and its key starting material
WO2012072713A2 (en) 2010-11-30 2012-06-07 Oryzon Genomics, S.A. Lysine demethylase inhibitors for diseases and disorders associated with flaviviridae
WO2012085665A2 (en) 2010-12-20 2012-06-28 Actavis Group Patc Ehf Novel processes for preparing triazolo[4,5-d]pyrimidine derivatives and intermediates thereof
EP3981395A1 (en) 2011-02-08 2022-04-13 Oryzon Genomics, S.A. Lysine demethylase inhibitors for myeloproliferative disorders
CZ303364B6 (cs) 2011-04-19 2012-08-15 Zentiva, K.S. Opticky aktivní soli (3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyklopenta-[d][1,3]dioxol-4-olu a zpusob jejich prípravy
RS54443B1 (en) * 2011-05-13 2016-06-30 Astrazeneca Ab PROCESS FOR PREPARATION OF BENZYL [(3AS, 4R, 6S, 6AR) -6-HYDROXY-2,2-DIMETHYLTETRAHYDRO-3AH-CYCLOPENT [D] [1,3] DIOXOL] -4-IL] CARBAMATE AND INTERMEDIATES FROM PROCESS
WO2012172426A1 (en) 2011-06-15 2012-12-20 Actavis Group Ptc Ehf Improved process for preparing cyclopentylamine derivatives and intermediates thereof
CN102924457A (zh) * 2011-08-12 2013-02-13 上海恒瑞医药有限公司 三唑并嘧啶类衍生物、其制备方法及其用途
EP3736265A1 (en) 2011-10-20 2020-11-11 Oryzon Genomics, S.A. (hetero)aryl cyclopropylamine compounds as lsd1 inhibitors
RS58475B1 (sr) 2011-10-20 2019-04-30 Oryzon Genomics Sa Jedinjenja (hetero)aril ciklopropilamina kao lsd1 inhibitori
CN102659691B (zh) * 2012-05-23 2014-04-02 山东诚创医药技术开发有限公司 一种4,6-二氯-5-氨基-2-丙硫基嘧啶的制备方法
DK3067358T3 (da) 2012-12-21 2019-11-04 Gilead Sciences Inc Polycykliske carbamoylpyridon-forbindelser og deres farmaceutiske anvendelse
WO2014206187A1 (zh) 2013-06-24 2014-12-31 苏州明锐医药科技有限公司 替卡格雷及其中间体的制备方法
NO2865735T3 (no) 2013-07-12 2018-07-21
PT3019503T (pt) 2013-07-12 2017-11-27 Gilead Sciences Inc Compostos carbamoílpiridona- policíclicos e seu uso para o tratamento de infecções por hiv
WO2015162630A1 (en) 2014-04-25 2015-10-29 Anlon Chemical Research Organization Novel processes for preparing triazolo [4,5-d]- pyrimidines, including ticagrelor, vianew intermediates and new route of synthesis.
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
NO2717902T3 (no) 2014-06-20 2018-06-23
TWI744723B (zh) 2014-06-20 2021-11-01 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
EP3600292A4 (en) 2017-03-30 2021-04-07 Corvus Pharmaceuticals, Inc. PROCESS FOR THE MANUFACTURING OF TRIAZOLE [4,5D] PYRAMIDINE DERIVATIVES AND INTERMEDIATES THEREOF
EP3619198B1 (en) * 2017-07-18 2020-06-17 Lonza Ltd Method for preparation of chlorinated s-propylthiobarbituric acid
WO2020068583A1 (en) * 2018-09-27 2020-04-02 Corvus Pharmaceuticals, Inc. Processes for making triazolo [4,5d] pyramidine derivatives and intermediates thereof
CN111116592A (zh) * 2019-11-27 2020-05-08 杭州沧海帆医药科技有限公司 嘧啶并三氮唑类化合物及其医药用途
CN115710275B (zh) * 2022-11-21 2024-02-02 河南中医药大学 一种嘧啶-tcp类化合物、制备方法和医药用途

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US4742064A (en) * 1985-09-10 1988-05-03 Regents Of The University Of Minnesota Antiviral carbocyclic analogs of xylofuranosylpurines
GB8826205D0 (en) * 1988-11-09 1988-12-14 Wellcome Found Heterocyclic compounds
BR9609467A (pt) * 1995-07-11 1999-03-02 Astra Pharma Prod Composto uso de um composto composição farmacéutica e processos para preparação de um composto e tratamento de distúrbios de agregação planquetária
EP0946561B1 (en) * 1996-12-20 2002-02-13 AstraZeneca AB Triazolo(4,5-d)pyrimidinyl derivatives and their use as medicaments

Also Published As

Publication number Publication date
IL134112A0 (en) 2001-07-24
KR20010022082A (ko) 2001-03-15
SK188099A3 (en) 2000-08-14
PL338518A1 (en) 2000-11-06
HUP0100202A2 (hu) 2001-08-28
EP0996620A1 (en) 2000-05-03
JP2001510841A (ja) 2001-08-07
CA2296648A1 (en) 1999-02-04
TR200000151T2 (tr) 2000-09-21
EE200000042A (et) 2000-10-16
ID24837A (id) 2000-08-24
DE69804964T2 (de) 2002-11-07
EP0996620B1 (en) 2002-04-17
HUP0100202A3 (en) 2001-10-29
DE69804964D1 (de) 2002-05-23
ATE216389T1 (de) 2002-05-15
CN1271359A (zh) 2000-10-25
BR9811022A (pt) 2000-09-12
NO20000311D0 (no) 2000-01-21
IS5351A (is) 2000-01-19
NO20000311L (no) 2000-03-21
AU8370598A (en) 1999-02-16
WO1999005142A1 (en) 1999-02-04
US6156756A (en) 2000-12-05

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