SE8800207D0 - Nya aminer, deras anvendning och framstellning - Google Patents

Nya aminer, deras anvendning och framstellning

Info

Publication number
SE8800207D0
SE8800207D0 SE8800207A SE8800207A SE8800207D0 SE 8800207 D0 SE8800207 D0 SE 8800207D0 SE 8800207 A SE8800207 A SE 8800207A SE 8800207 A SE8800207 A SE 8800207A SE 8800207 D0 SE8800207 D0 SE 8800207D0
Authority
SE
Sweden
Prior art keywords
methyl
preparing
same
novel
manufacturing
Prior art date
Application number
SE8800207A
Other languages
English (en)
Swedish (sv)
Inventor
N A Jonsson
B A Sparf
L Mikiver
P Moses
L Nilvebrant
G Glas
Original Assignee
Kabivitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20371146&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE8800207(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kabivitrum Ab filed Critical Kabivitrum Ab
Priority to SE8800207A priority Critical patent/SE8800207D0/xx
Publication of SE8800207D0 publication Critical patent/SE8800207D0/xx
Priority to HU891069A priority patent/HU212729B/hu
Priority to PCT/SE1989/000016 priority patent/WO1989006644A1/fr
Priority to CA000588821A priority patent/CA1340223C/fr
Priority to JP1501413A priority patent/JP2664503B2/ja
Priority to EP89901611A priority patent/EP0354234A1/fr
Priority to DE1998175024 priority patent/DE19875024I2/de
Priority to DE8989850017T priority patent/DE68900180D1/de
Priority to ES89850017T priority patent/ES2029384T4/es
Priority to AT89850017T priority patent/ATE65990T1/de
Priority to EP89850017A priority patent/EP0325571B1/fr
Priority to AU29329/89A priority patent/AU635493B2/en
Priority to NO903085A priority patent/NO173496C/no
Priority to DK172590A priority patent/DK172103B1/da
Priority to FI903688A priority patent/FI109900B/fi
Priority to GR91401499T priority patent/GR3002854T3/el
Priority to US07/810,185 priority patent/US5382600A/en
Priority to HK64494A priority patent/HK64494A/xx
Priority to HU94P/P00053P priority patent/HU210603A9/hu
Priority to NL980020C priority patent/NL980020I2/nl
Priority to LU90259C priority patent/LU90259I2/fr
Priority to NO1998023C priority patent/NO1998023I1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Lubricants (AREA)
  • Steroid Compounds (AREA)
SE8800207A 1988-01-22 1988-01-22 Nya aminer, deras anvendning och framstellning SE8800207D0 (sv)

Priority Applications (22)

Application Number Priority Date Filing Date Title
SE8800207A SE8800207D0 (sv) 1988-01-22 1988-01-22 Nya aminer, deras anvendning och framstellning
AU29329/89A AU635493B2 (en) 1988-01-22 1989-01-20 New amines, their use and preparation
PCT/SE1989/000016 WO1989006644A1 (fr) 1988-01-22 1989-01-20 Nouvelles amines, leur utilisation et leur preparation
AT89850017T ATE65990T1 (de) 1988-01-22 1989-01-20 Amine, ihre verwendung und herstellung.
EP89850017A EP0325571B1 (fr) 1988-01-22 1989-01-20 Amines, leur utilisation et leur préparation
CA000588821A CA1340223C (fr) 1988-01-22 1989-01-20 3,3-diphenylpropylamines et leurs compositions pharmaceutiques; utilisation dans des systemes cholinergiques
JP1501413A JP2664503B2 (ja) 1988-01-22 1989-01-20 新規アミン、その使用及び製法
EP89901611A EP0354234A1 (fr) 1988-01-22 1989-01-20 Nouvelles amines, leur utilisation et leur preparation
DE1998175024 DE19875024I2 (de) 1988-01-22 1989-01-20 Amine Ihre verwendung und Herstellung
DE8989850017T DE68900180D1 (de) 1988-01-22 1989-01-20 Amine, ihre verwendung und herstellung.
ES89850017T ES2029384T4 (es) 1988-01-22 1989-01-20 Procedimiento para preparar nuevas 3,3-difenilpropilaminas.
HU891069A HU212729B (en) 1988-01-22 1989-01-20 Process for producing 3,3-diphenyl propyl amino derivate and pharmaceutical compositions containing such
NO903085A NO173496C (no) 1988-01-22 1990-07-11 Analogifremgangsmaate ved fremstilling av terapeutisk aktive 3,3- difenyl-propylaminer
DK172590A DK172103B1 (da) 1988-01-22 1990-07-19 Hidtil ukendte 3,3-difenylpropylaminer, farmaceutiske præparater indeholdende disse, deres anvendelse til fremstilling af et anticholinergt lægemiddel samt fremgangsmåde til deres fremstilling
FI903688A FI109900B (fi) 1988-01-22 1990-07-20 Menetelmä farmaseuttisesti aktiivisten 3,3-difenyylipropyyliamiinien valmistamiseksi
GR91401499T GR3002854T3 (en) 1988-01-22 1991-10-08 New amines, their use and preparation
US07/810,185 US5382600A (en) 1988-01-22 1991-12-19 3,3-diphenylpropylamines and pharmaceutical compositions thereof
HK64494A HK64494A (en) 1988-01-22 1994-07-07 New amines, their use and preparation
HU94P/P00053P HU210603A9 (en) 1988-01-22 1994-12-15 New amines, their use and preparation
NL980020C NL980020I2 (nl) 1988-01-22 1998-06-19 Nieuwe aminen, de toepassing ervan en de bereiding.
LU90259C LU90259I2 (fr) 1988-01-22 1998-07-03 N,n-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropanamine et les sels racémates et énantiomères de celle-ci
NO1998023C NO1998023I1 (no) 1988-01-22 1998-10-20 Tolterodin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8800207A SE8800207D0 (sv) 1988-01-22 1988-01-22 Nya aminer, deras anvendning och framstellning

Publications (1)

Publication Number Publication Date
SE8800207D0 true SE8800207D0 (sv) 1988-01-22

Family

ID=20371146

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8800207A SE8800207D0 (sv) 1988-01-22 1988-01-22 Nya aminer, deras anvendning och framstellning

Country Status (17)

Country Link
EP (2) EP0354234A1 (fr)
JP (1) JP2664503B2 (fr)
AT (1) ATE65990T1 (fr)
AU (1) AU635493B2 (fr)
CA (1) CA1340223C (fr)
DE (2) DE68900180D1 (fr)
DK (1) DK172103B1 (fr)
ES (1) ES2029384T4 (fr)
FI (1) FI109900B (fr)
GR (1) GR3002854T3 (fr)
HK (1) HK64494A (fr)
HU (2) HU212729B (fr)
LU (1) LU90259I2 (fr)
NL (1) NL980020I2 (fr)
NO (2) NO173496C (fr)
SE (1) SE8800207D0 (fr)
WO (1) WO1989006644A1 (fr)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9203318D0 (sv) * 1992-11-06 1992-11-06 Kabi Pharmacia Ab Novel 3,3-diphenylpropylamines, their use and preparation
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
ZA969363B (en) * 1995-11-08 1997-11-18 Smithkline Beecham Corp An improved process for preparing aromatic ring-fused cyclopentane derivatives.
EP0924983A4 (fr) * 1996-07-19 1999-08-25 Gunnar Aberg S(-)-tolterodine pour le traitement des troubles urinaires et gastro-intestinaux
KR20000057548A (ko) * 1996-12-13 2000-09-25 알프레드 엘. 미첼슨 광학적 전송물질 및 결합재
SE9701144D0 (sv) * 1997-03-27 1997-03-27 Pharmacia & Upjohn Ab Novel compounds, their use and preparation
EP0957073A1 (fr) * 1998-05-12 1999-11-17 Schwarz Pharma Ag Dérivés de 3,3-diphénylpropylamines
PT1039882E (pt) 1998-08-27 2011-01-03 Pfizer Health Ab Formulação terapêutica para administrar tolterodina com libertação controlada
DE19955190A1 (de) * 1999-11-16 2001-06-21 Sanol Arznei Schwarz Gmbh Stabile Salze neuartiger Derivate von 3,3-Diphenylpropylaminen
US6566537B2 (en) 1999-12-30 2003-05-20 Pharmacia Ab Process and intermediates
SE9904850D0 (sv) 1999-12-30 1999-12-30 Pharmacia & Upjohn Ab Novel process and intermediates
DE10028443C1 (de) * 2000-06-14 2002-05-29 Sanol Arznei Schwarz Gmbh Verfahren zur Herstellung von 3,3-Diarylpropylaminen, (R,S)- und (R)-4-Phenyl-2-chromanon-6-carbonsäure sowie (R)-4-Phenyl-2-chromanon-carbonsäure-cinchonidinsalz und deren Verwendung zur Herstellung eines rechtsdrehenden Hydroxybenzylalkohols und von pharmazeutischen Zusammensetzungen
DE10033016A1 (de) * 2000-07-07 2002-01-24 Sanol Arznei Schwarz Gmbh Verfahren zur Herstellung von 3,3-Diarylpropylaminen
BR0206300A (pt) * 2001-11-05 2008-04-08 Upjohn Co composição farmacêutica para tratar distúrbio urinário em um mamìfero e uso
US7670612B2 (en) 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
DE60230683D1 (de) 2002-07-08 2009-02-12 Ranbaxy Lab Ltd 3,6-disubstituierte azabicyclo-3.1.0 hexan-derivat
DE60226906D1 (de) 2002-07-31 2008-07-10 Ranbaxy Lab Ltd 3,6-disubstituierte azabicyclo ä3.1.0ühexanderivate, die sich als muscarinrezeptorantagonisten eignen
US7410993B2 (en) 2002-08-09 2008-08-12 Ranbaxy Laboratories Limited 3,6-disubstituted azabicyclo [3.1.0] hexane deriviatives useful as muscarinic receptor antagonists
DE60231341D1 (de) 2002-08-23 2009-04-09 Ranbaxy Lab Ltd Fluor- und sulfonylaminohaltige, 3,6-disubstituierptorantagonisten
US7232835B2 (en) 2002-12-10 2007-06-19 Ranbaxy Laboratories Limited 3,6-Disubstituted azabicyclo derivatives as muscarinic receptor antagonists
JP2006511606A (ja) 2002-12-13 2006-04-06 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 下部尿路症状を治療するα−２−δリガンド
WO2004056811A1 (fr) 2002-12-23 2004-07-08 Ranbaxy Laboratories Limited Derives de flavaxate comme antagonistes de recepteurs muscariniques
EP1583741A1 (fr) 2002-12-23 2005-10-12 Ranbaxy Laboratories, Limited Derives de 1-substitues-3-pyrrolidines comme antagonistes de recepteurs muscariniques
MXPA05007767A (es) 2003-01-22 2006-01-31 Pfizer Health Ab Dosis reducida de tolterodina y otros agentes antimuscarinicos para tratar trastornos urinarios.
US7488748B2 (en) 2003-01-28 2009-02-10 Ranbaxy Laboratories Limited 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists
AU2004218178A1 (en) * 2003-03-06 2004-09-16 Ranbaxy Laboratories Limited 3,3-diarylpropylamine derivatives and processes for isolation thereof
WO2004089281A2 (fr) * 2003-04-08 2004-10-21 Hetero Drugs Limited Nouveaux corps polymorphes de tartrate de tolterodine
DE10315917A1 (de) * 2003-04-08 2004-11-18 Schwarz Pharma Ag Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
EP1618091A1 (fr) 2003-04-09 2006-01-25 Ranbaxy Laboratories, Ltd. Derives d'azabicyclo hexane substitues en tant qu'antagonistes de recepteurs muscariniques
ATE362364T1 (de) 2003-04-10 2007-06-15 Ranbaxy Lab Ltd Substituierte azabicyclo hexane derivate als muscarin rezeptor antagonisten
EP1615887A1 (fr) 2003-04-10 2006-01-18 Ranbaxy Laboratories, Ltd. Derives d'azabicyclo hexanes en tant qu'antagonistes des recepteurs muscariniques
CN100436414C (zh) 2003-04-11 2008-11-26 兰贝克赛实验室有限公司 作为毒蕈碱受体拮抗剂的氮杂双环衍生物
BRPI0409653A (pt) 2003-04-25 2006-04-25 Pharmacia & Upjohn Co Llc 3,3-difenilpropilaminas (tolterodina) substituìdas com halogênio com atividade antimuscarìnica
ATE545627T1 (de) * 2003-05-23 2012-03-15 Bridge Pharma Inc Glattmuskelspasmolytika
ES2235648B1 (es) * 2003-12-22 2006-11-01 Ragactives, S.L. Procedimiento para la obtencion de tolterodina.
WO2005061432A1 (fr) * 2003-12-24 2005-07-07 Cipla Limited Tolterodine, compositions et leurs utilisations, et preparations desdites compositions
EP1629834A1 (fr) 2004-08-27 2006-03-01 KRKA, D.D., Novo Mesto Composition pharmaceutique de tolterodine avec liberation soutenue
JP4513535B2 (ja) * 2004-12-03 2010-07-28 住友化学株式会社 トルテロジンの製造方法
AU2005318426B2 (en) * 2004-12-24 2011-05-19 Lek Pharmaceuticals D.D. Process for preparation of 3-(2-hydroxy-5-methylphenyl)-N,N-diisopropyl-3-phenylpropylamine
ITMI20050249A1 (it) 2005-02-18 2006-08-19 Dipharma Spa Procedimento per la preparazione di tolterodina
WO2007039918A1 (fr) * 2005-10-06 2007-04-12 Natco Pharma Limited Nouveau procede de preparation de tolterodine
US20090221664A1 (en) 2005-10-19 2009-09-03 Abhijit Ray Pharmaceutical compositions of muscarinic receptor antagonists
EP1965863A2 (fr) * 2005-12-20 2008-09-10 Pfizer Products Inc. Combinaison pharmaceutique utilisee pour traiter des troubles urinaires du bas appareil (tuba)
ITMI20060110A1 (it) * 2006-01-24 2007-07-25 Dipharma Spa Procedimento per la purificazione di tolterodina
AU2007228511A1 (en) 2006-03-20 2007-09-27 Pfizer Limited Amine derivatives
DK2027103T3 (da) 2006-06-12 2014-04-22 Ucb Pharma Gmbh Nyt chiralt mellemprodukt, fremgangsmåde til fremstilling deraf og dets anvendelse i fremstillingen af tolterodin, fesoterodin, eller den aktive metabolit deraf
WO2007147547A1 (fr) 2006-06-20 2007-12-27 Lek Pharmaceuticals D.D. Procédé de préparation de 3-(2-hydroxy-5-(phényle substitué))-n-alkyl-3-phénylpropylamines
CZ302585B6 (cs) * 2007-02-26 2011-07-20 Zentiva, A. S. Krystalická sul 2-[(1R)-3-[bis(1-methylethyl)amino]-1-fenylpropyl]-4-methylfenolu s kyselinou (2R,3R)-2,3-dihydroxybutandiovou
EP2054372A2 (fr) * 2006-08-09 2009-05-06 Zentiva, k.s. Tartrate de toltérodine cristallin et composition pharmaceutique le contenant
ITMI20082055A1 (it) * 2008-11-19 2009-02-18 Dipharma Francis Srl Procedimento per la preparazione di (r)-tolterodina base libera
PL2416761T3 (pl) * 2009-05-11 2015-07-31 Ratiopharm Gmbh Desfezoterodyna w postaci soli kwasu winowego
IL210279A0 (en) 2009-12-25 2011-03-31 Dexcel Pharma Technologies Ltd Extended release compositions for high solubility, high permeability acdtive pharmaceutical ingredients
EP2364966A1 (fr) 2010-03-09 2011-09-14 LEK Pharmaceuticals d.d. Procédé pour la préparation de 3-(2-hydroxy-5-substitue phényl)-3-phénylpropylamines, intermédiaires pour la préparation de tolterodine
CN102329244A (zh) * 2010-07-13 2012-01-25 凯瑞斯德生化(苏州)有限公司 一种rs-托特罗定的制备方法及中间体化合物
ITMI20110410A1 (it) * 2011-03-15 2012-09-16 Cambrex Profarmaco Milano Srl Procedimento per la preparazione di (r)-tolterodina l-tartrato di forma cristallina definita
ITMI20121232A1 (it) 2012-07-16 2014-01-17 Cambrex Profarmaco Milano Srl Procedimento per la preparazione di 2-(3-n,n-diisopropilamino-1-fenilpropil)-4-idrossimetil-fenolo e suoi derivati
CN110372571B (zh) 2018-04-12 2022-11-15 中国科学院大连化学物理研究所 一种2-(2,2-二芳基乙基)-环胺衍生物或盐及合成和应用与组合物
WO2022256480A1 (fr) * 2021-06-03 2022-12-08 Conagen Inc. Synthèse d'arylcoumarine avec élimination azéotropique de l'eau

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK111894A (fr) * 1962-11-15
GB1169945A (en) * 1966-08-25 1969-11-05 Geistlich Soehne Ag Pharmaceutical Compositions containing Diphenylalkyl-amine Derivatives
GB1169944A (en) * 1966-08-25 1969-11-05 Geistlich Soehne Ag Novel 3,3-Diphenylpropylamines and processes for the preparation thereof

Also Published As

Publication number Publication date
EP0354234A1 (fr) 1990-02-14
FI903688A0 (fi) 1990-07-20
JP2664503B2 (ja) 1997-10-15
DK172590A (da) 1990-07-19
DK172590D0 (da) 1990-07-19
NO903085D0 (no) 1990-07-11
NL980020I1 (nl) 1998-09-01
CA1340223C (fr) 1998-12-15
NO1998023I1 (no) 1998-10-20
EP0325571A1 (fr) 1989-07-26
NL980020I2 (nl) 1999-02-01
HU210603A9 (en) 1995-05-29
JPH03503163A (ja) 1991-07-18
HK64494A (en) 1994-07-15
ES2029384T3 (es) 1992-08-01
DK172103B1 (da) 1997-10-27
DE68900180D1 (de) 1991-09-12
AU635493B2 (en) 1993-03-25
EP0325571B1 (fr) 1991-08-07
HUT58040A (en) 1992-01-28
DE19875024I2 (de) 2002-09-26
NO173496C (no) 1993-12-22
LU90259I2 (fr) 1998-09-16
NO903085L (no) 1990-07-11
WO1989006644A1 (fr) 1989-07-27
HU891069D0 (en) 1991-11-28
AU2932989A (en) 1989-08-11
FI109900B (fi) 2002-10-31
GR3002854T3 (en) 1993-01-25
ATE65990T1 (de) 1991-08-15
HU212729B (en) 1996-10-28
NO173496B (no) 1993-09-13
ES2029384T4 (es) 2011-05-30

Similar Documents

Publication Publication Date Title
SE8800207D0 (sv) Nya aminer, deras anvendning och framstellning
FI952179A0 (fi) Uusia 3,3-difenyylipropyyliamiineja, niiden käyttö ja valmistus
ZA932168B (en) Naphthylalkylamines, process for preparing them and pharmaceutical compositions containing them
FR2695387B1 (fr) Nouveaux composés benzopyraniques, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
DE68905363D1 (de) Heterotetracyclische laktamderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.
GR3021765T3 (en) Aminoalkylchomones, process for their preparation and pharmaceutical compositions containing them.
IT1229846B (it) Esteri di catecolammine.
ATE39352T1 (de) Ergolinderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.