SE8301794D0 - Plasminogenaktivatorkomplex - Google Patents

Plasminogenaktivatorkomplex

Info

Publication number
SE8301794D0
SE8301794D0 SE8301794A SE8301794A SE8301794D0 SE 8301794 D0 SE8301794 D0 SE 8301794D0 SE 8301794 A SE8301794 A SE 8301794A SE 8301794 A SE8301794 A SE 8301794A SE 8301794 D0 SE8301794 D0 SE 8301794D0
Authority
SE
Sweden
Prior art keywords
plasmin
plasminogen
complex
streptokinase
activity
Prior art date
Application number
SE8301794A
Other languages
English (en)
Other versions
SE454047B (sv
Inventor
K C Robbins
L Summaria
Original Assignee
Reese Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reese Res Found filed Critical Reese Res Found
Publication of SE8301794D0 publication Critical patent/SE8301794D0/sv
Publication of SE454047B publication Critical patent/SE454047B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SE8301794A 1976-09-24 1983-03-30 Forfarande for framstellning av ett komplex av streptokinas och en lett plasminkedja med ett serinproteasaktivt centrum SE454047B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/726,142 US4082612A (en) 1976-09-24 1976-09-24 Plasminogen activator complex

Publications (2)

Publication Number Publication Date
SE8301794D0 true SE8301794D0 (sv) 1983-03-30
SE454047B SE454047B (sv) 1988-03-28

Family

ID=24917422

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7710653A SE442304B (sv) 1976-09-24 1977-09-22 Forfarande for framstellning av en lett plasminkedja med ett serinproteasaktivt centrum
SE8301795A SE454048B (sv) 1976-09-24 1983-03-30 Forfarande for framstellning av ett komplex av streptokinas och en lett plasminkedja med ett serinproteasaktivt centrum
SE8301794A SE454047B (sv) 1976-09-24 1983-03-30 Forfarande for framstellning av ett komplex av streptokinas och en lett plasminkedja med ett serinproteasaktivt centrum

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE7710653A SE442304B (sv) 1976-09-24 1977-09-22 Forfarande for framstellning av en lett plasminkedja med ett serinproteasaktivt centrum
SE8301795A SE454048B (sv) 1976-09-24 1983-03-30 Forfarande for framstellning av ett komplex av streptokinas och en lett plasminkedja med ett serinproteasaktivt centrum

Country Status (10)

Country Link
US (1) US4082612A (sv)
JP (1) JPS5352606A (sv)
CA (1) CA1094449A (sv)
CH (2) CH637991A5 (sv)
DE (1) DE2742529C2 (sv)
DK (1) DK421577A (sv)
FR (1) FR2365583A1 (sv)
GB (1) GB1533205A (sv)
NL (1) NL7710451A (sv)
SE (3) SE442304B (sv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0028489B1 (en) * 1979-11-05 1983-10-05 Beecham Group Plc Enzyme derivatives, and their preparation
JPS58189122A (ja) * 1982-04-30 1983-11-04 Kaken Pharmaceut Co Ltd 高脂血症予防治療剤
US4536391A (en) * 1982-11-17 1985-08-20 Otsuka Pharmaceutical Co. Process for preparing urokinase complex
JPS60136520A (ja) * 1983-12-23 1985-07-20 Otsuka Pharmaceut Co Ltd フイブリン吸着性ウロキナ−ゼ複合体
GB8334499D0 (en) * 1983-12-24 1984-02-01 Beecham Group Plc Derivatives
US4880776A (en) * 1983-12-24 1989-11-14 Beecham Group P.L.C. Plasmin A-chain urokinase B-chain hybrid protein
GB8334498D0 (en) * 1983-12-24 1984-02-01 Beecham Group Plc Compounds
GB8400653D0 (en) * 1984-01-11 1984-02-15 Beecham Group Plc Conjugates
EP0156169B1 (en) * 1984-02-29 1991-12-18 Asahi Kasei Kogyo Kabushiki Kaisha An aqueous solution of a tissue plasminogen activator dissolved therein at an increased concentration and a method
US4774087A (en) * 1987-08-14 1988-09-27 Northwestern University Micro-size fibrinolytic plasmin
DE3833936C1 (sv) * 1988-10-05 1989-09-21 Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin, De
US6355243B1 (en) 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
US6964764B2 (en) * 1999-11-13 2005-11-15 Talecris Biotherapeutics, Inc. Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
US7544500B2 (en) * 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
US6969515B2 (en) 1999-11-13 2005-11-29 Talecris Biotherapeutics, Inc. Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin
BRPI0913397B8 (pt) * 2008-06-04 2021-05-25 Grifols Therapeutics Inc método para preparar plasmina
US9206410B2 (en) 2009-03-03 2015-12-08 Grifols Therapeutics Inc. Compositions, methods and kits for preparing plasminogen and plasmin prepared therefrom

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3865692A (en) * 1974-01-11 1975-02-11 Abbott Lab Method for making highly potent plasminogen

Also Published As

Publication number Publication date
US4082612A (en) 1978-04-04
FR2365583B1 (sv) 1981-07-10
SE8301795D0 (sv) 1983-03-30
DE2742529C2 (de) 1984-01-05
DE2742529A1 (de) 1978-03-30
SE7710653L (sv) 1978-03-25
NL7710451A (nl) 1978-03-29
JPS5352606A (en) 1978-05-13
SE442304B (sv) 1985-12-16
SE454047B (sv) 1988-03-28
CA1094449A (en) 1981-01-27
FR2365583A1 (fr) 1978-04-21
CH637992A5 (de) 1983-08-31
GB1533205A (en) 1978-11-22
SE8301795L (sv) 1983-03-30
SE454048B (sv) 1988-03-28
DK421577A (da) 1978-03-25
CH637991A5 (de) 1983-08-31

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