SE8105995L - NEW 3-AMINO-SUBSTITUTED STEROIDS AND THEIR SALTS, SET FOR PREPARATION AND USE THEREOF AS MEDICINAL PRODUCTS AND COMPOSITIONS CONTAINING THEM - Google Patents

NEW 3-AMINO-SUBSTITUTED STEROIDS AND THEIR SALTS, SET FOR PREPARATION AND USE THEREOF AS MEDICINAL PRODUCTS AND COMPOSITIONS CONTAINING THEM

Info

Publication number
SE8105995L
SE8105995L SE8105995A SE8105995A SE8105995L SE 8105995 L SE8105995 L SE 8105995L SE 8105995 A SE8105995 A SE 8105995A SE 8105995 A SE8105995 A SE 8105995A SE 8105995 L SE8105995 L SE 8105995L
Authority
SE
Sweden
Prior art keywords
salts
preparation
new
amino
compositions containing
Prior art date
Application number
SE8105995A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE451456B (en
Inventor
P Deraedt
V Torelli
J Benzoni
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of SE8105995L publication Critical patent/SE8105995L/en
Publication of SE451456B publication Critical patent/SE451456B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0027—Azides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The title compounds of formula I and their salts are, with certain exceptions, new: <IMAGE> W is H or OH; X is ethyl, 1-hydroxyethyl, or acetyl; or W + X = ethylidene; R, is H or Me; R2 and R3 are each H, alkyl or hydroxyalkyl, R3 alternatively being acyl (including alkoxycarbonyl and radicals derived from amino acids and peptides), and at least one of R2 and R3 being other than H. Preparation: from the corresponding primary amines (R2 = R3 = H) Use: treatment of autoimmune diseases. <IMAGE>
SE8105995A 1980-11-21 1981-10-09 NEW 3-AMINO-SUBSTITUTED STEROIDS AND THEIR SALTS, SET FOR PREPARATION OF THEM AND COMPOSITIONS CONTAINING THEM SE451456B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8024750A FR2494698A1 (en) 1980-11-21 1980-11-21 NOVEL SUBSTITUTED 3-AMINO STEROID DERIVATIVES, THEIR SALTS, PREPARATION METHOD, MEDICAMENT APPLICATION AND COMPOSITIONS COMPRISING THE SAME

Publications (2)

Publication Number Publication Date
SE8105995L true SE8105995L (en) 1982-05-22
SE451456B SE451456B (en) 1987-10-12

Family

ID=9248226

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8105995A SE451456B (en) 1980-11-21 1981-10-09 NEW 3-AMINO-SUBSTITUTED STEROIDS AND THEIR SALTS, SET FOR PREPARATION OF THEM AND COMPOSITIONS CONTAINING THEM

Country Status (23)

Country Link
JP (1) JPS57116099A (en)
KR (1) KR880001239B1 (en)
AT (1) AT389703B (en)
AU (1) AU546100B2 (en)
BE (1) BE891201A (en)
CA (1) CA1175415A (en)
CH (1) CH651056A5 (en)
DE (1) DE3146117A1 (en)
DK (1) DK161093C (en)
ES (1) ES507309A0 (en)
FI (1) FI77871C (en)
FR (1) FR2494698A1 (en)
GB (1) GB2087894B (en)
HU (1) HU184896B (en)
IE (1) IE52188B1 (en)
IL (1) IL64224A0 (en)
IT (1) IT1172086B (en)
LU (1) LU83781A1 (en)
NL (1) NL8105260A (en)
PT (1) PT74015B (en)
SE (1) SE451456B (en)
SU (1) SU1327789A3 (en)
ZA (1) ZA817806B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9084800B2 (en) * 2011-11-07 2015-07-21 Natreon, Inc. Indolealkylamino-withasteroid conjugates and method of use

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2430467A (en) * 1944-02-11 1947-11-11 Glidden Co 3-amino-derivatives of steroids and method of making same
US2781342A (en) * 1952-05-17 1957-02-12 Upjohn Co Steroid enamines
GB962324A (en) * 1959-09-12 1964-07-01 Clin Byla Ets Steroid compounds and production thereof
FR1311761A (en) * 1959-09-12 1962-12-14 Clin Byla Ets Amino compounds of the steroid series and method of preparing such compounds
NL103735C (en) * 1961-02-17
US3503959A (en) * 1962-03-30 1970-03-31 Sterling Drug Inc 3-amino steroids
US3196168A (en) * 1964-02-18 1965-07-20 American Home Prod Aminoaroyl aminosteroids
BE647858A (en) * 1964-05-13
US3196169A (en) * 1964-11-03 1965-07-20 American Home Prod Aminoacyl aminosteroids
BE672238A (en) * 1965-11-12 1966-03-01
BE811304R (en) * 1973-10-24 1974-06-17 PREPARATION PROCEDURE FOR (20 S) 3 BETA -N-DIMETHYLAMINO
FR2463777A1 (en) * 1979-08-17 1981-02-27 Roussel Uclaf NOVEL DERIVATIVES OF 5A-PREGNAN-20-OL, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS

Also Published As

Publication number Publication date
GB2087894A (en) 1982-06-03
IE812732L (en) 1982-05-21
DK161093B (en) 1991-05-27
KR830007716A (en) 1983-11-04
PT74015B (en) 1983-11-30
FI77871C (en) 1989-05-10
CA1175415A (en) 1984-10-02
BE891201A (en) 1982-05-21
IL64224A0 (en) 1982-02-28
DK161093C (en) 1991-11-18
IT8149746A0 (en) 1981-11-20
DE3146117A1 (en) 1982-06-16
NL8105260A (en) 1982-06-16
PT74015A (en) 1981-12-01
ES8207195A1 (en) 1982-09-01
FR2494698A1 (en) 1982-05-28
ES507309A0 (en) 1982-09-01
DK514981A (en) 1982-05-22
LU83781A1 (en) 1982-06-30
ZA817806B (en) 1982-10-27
SU1327789A3 (en) 1987-07-30
IT1172086B (en) 1987-06-18
GB2087894B (en) 1984-09-26
JPS57116099A (en) 1982-07-19
AT389703B (en) 1990-01-25
FI77871B (en) 1989-01-31
FR2494698B1 (en) 1983-06-24
SE451456B (en) 1987-10-12
KR880001239B1 (en) 1988-07-12
CH651056A5 (en) 1985-08-30
JPH0247479B2 (en) 1990-10-19
IE52188B1 (en) 1987-08-05
HU184896B (en) 1984-10-29
AU546100B2 (en) 1985-08-15
FI813677L (en) 1982-05-22
AU7772381A (en) 1982-05-27
ATA497081A (en) 1989-06-15

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