IE812732L - 3-amino steroid compounds - Google Patents

3-amino steroid compounds

Info

Publication number
IE812732L
IE812732L IE812732A IE273281A IE812732L IE 812732 L IE812732 L IE 812732L IE 812732 A IE812732 A IE 812732A IE 273281 A IE273281 A IE 273281A IE 812732 L IE812732 L IE 812732L
Authority
IE
Ireland
Prior art keywords
steroid compounds
image
amino steroid
amino
gb2087894a
Prior art date
Application number
IE812732A
Other versions
IE52188B1 (en
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of IE812732L publication Critical patent/IE812732L/en
Publication of IE52188B1 publication Critical patent/IE52188B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0027—Azides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The title compounds of formula I and their salts are, with certain exceptions, new: <IMAGE> W is H or OH; X is ethyl, 1-hydroxyethyl, or acetyl; or W + X = ethylidene; R, is H or Me; R2 and R3 are each H, alkyl or hydroxyalkyl, R3 alternatively being acyl (including alkoxycarbonyl and radicals derived from amino acids and peptides), and at least one of R2 and R3 being other than H. Preparation: from the corresponding primary amines (R2 = R3 = H) Use: treatment of autoimmune diseases. <IMAGE> [GB2087894A]
IE2732/81A 1980-11-21 1981-11-20 New 3-amino steroid compounds,their production and pharmaceutical compositions containing them IE52188B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8024750A FR2494698A1 (en) 1980-11-21 1980-11-21 NOVEL SUBSTITUTED 3-AMINO STEROID DERIVATIVES, THEIR SALTS, PREPARATION METHOD, MEDICAMENT APPLICATION AND COMPOSITIONS COMPRISING THE SAME

Publications (2)

Publication Number Publication Date
IE812732L true IE812732L (en) 1982-05-21
IE52188B1 IE52188B1 (en) 1987-08-05

Family

ID=9248226

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2732/81A IE52188B1 (en) 1980-11-21 1981-11-20 New 3-amino steroid compounds,their production and pharmaceutical compositions containing them

Country Status (23)

Country Link
JP (1) JPS57116099A (en)
KR (1) KR880001239B1 (en)
AT (1) AT389703B (en)
AU (1) AU546100B2 (en)
BE (1) BE891201A (en)
CA (1) CA1175415A (en)
CH (1) CH651056A5 (en)
DE (1) DE3146117A1 (en)
DK (1) DK161093C (en)
ES (1) ES8207195A1 (en)
FI (1) FI77871C (en)
FR (1) FR2494698A1 (en)
GB (1) GB2087894B (en)
HU (1) HU184896B (en)
IE (1) IE52188B1 (en)
IL (1) IL64224A0 (en)
IT (1) IT1172086B (en)
LU (1) LU83781A1 (en)
NL (1) NL8105260A (en)
PT (1) PT74015B (en)
SE (1) SE451456B (en)
SU (1) SU1327789A3 (en)
ZA (1) ZA817806B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9084800B2 (en) * 2011-11-07 2015-07-21 Natreon, Inc. Indolealkylamino-withasteroid conjugates and method of use

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2430467A (en) * 1944-02-11 1947-11-11 Glidden Co 3-amino-derivatives of steroids and method of making same
US2781342A (en) * 1952-05-17 1957-02-12 Upjohn Co Steroid enamines
FR1311761A (en) * 1959-09-12 1962-12-14 Clin Byla Ets Amino compounds of the steroid series and method of preparing such compounds
DE1189074B (en) * 1959-09-12 1965-03-18 Clin Byla Ets Process for the preparation of 3-amino compounds of the androstane or pregnane series
NL103735C (en) * 1961-02-17
US3503959A (en) * 1962-03-30 1970-03-31 Sterling Drug Inc 3-amino steroids
US3196168A (en) * 1964-02-18 1965-07-20 American Home Prod Aminoaroyl aminosteroids
BE647858A (en) * 1964-05-13
US3196169A (en) * 1964-11-03 1965-07-20 American Home Prod Aminoacyl aminosteroids
BE672238A (en) * 1965-11-12 1966-03-01
BE811304R (en) * 1973-10-24 1974-06-17 PREPARATION PROCEDURE FOR (20 S) 3 BETA -N-DIMETHYLAMINO
FR2463777A1 (en) * 1979-08-17 1981-02-27 Roussel Uclaf NOVEL DERIVATIVES OF 5A-PREGNAN-20-OL, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS

Also Published As

Publication number Publication date
CH651056A5 (en) 1985-08-30
IL64224A0 (en) 1982-02-28
AU546100B2 (en) 1985-08-15
BE891201A (en) 1982-05-21
SE8105995L (en) 1982-05-22
JPS57116099A (en) 1982-07-19
FI77871B (en) 1989-01-31
KR880001239B1 (en) 1988-07-12
DK161093C (en) 1991-11-18
IT8149746A0 (en) 1981-11-20
JPH0247479B2 (en) 1990-10-19
FI77871C (en) 1989-05-10
ES507309A0 (en) 1982-09-01
GB2087894B (en) 1984-09-26
IT1172086B (en) 1987-06-18
SU1327789A3 (en) 1987-07-30
LU83781A1 (en) 1982-06-30
IE52188B1 (en) 1987-08-05
FR2494698B1 (en) 1983-06-24
KR830007716A (en) 1983-11-04
DK161093B (en) 1991-05-27
DE3146117A1 (en) 1982-06-16
AT389703B (en) 1990-01-25
NL8105260A (en) 1982-06-16
FR2494698A1 (en) 1982-05-28
ES8207195A1 (en) 1982-09-01
PT74015B (en) 1983-11-30
SE451456B (en) 1987-10-12
GB2087894A (en) 1982-06-03
DK514981A (en) 1982-05-22
PT74015A (en) 1981-12-01
AU7772381A (en) 1982-05-27
ATA497081A (en) 1989-06-15
ZA817806B (en) 1982-10-27
CA1175415A (en) 1984-10-02
FI813677L (en) 1982-05-22
HU184896B (en) 1984-10-29

Similar Documents

Publication Publication Date Title
IL73893A (en) 11-aryl-13-estradiene derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
NO861723L (en) PROCEDURE FOR THE PREPARATION OF NEW TETRAPYR ROLLER DERIVATIVES
TW334418B (en) Stilbene derivatives and pharmaceutical compositions
DK446279A (en) PROCEDURE FOR PREPARING SUBSTITUTED 1-CARBA-2-PENEM-3-CARBOXYL ACIDS
ES2040373T3 (en) STEROIDS BRIDGED IN 19,11BETA, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS.
CZ85395A3 (en) Derivatives of vaprooic and 1-valproenic acids and pharmaceutical preparations based thereon
DE3262698D1 (en) Antifibrinolytically active compounds
ES8400393A1 (en) Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions.
EP0865434A4 (en)
TW249804B (en)
PT736029E (en) SULFAMATOS OF PSEUDOFRUCTOPIRANOSIS ANTICONVULSIVOS
AU546158B2 (en) Cycloaliphatic pharmaceutical compounds
IE812732L (en) 3-amino steroid compounds
TW252979B (en)
ES8605802A1 (en) Cinnamoyl compounds, process for their preparation and their therapeutical use
SE8302452D0 (en) METHOD FOR TREATMENT OF SENILE DEMENTIA
ES2049186A1 (en) Benzofuranylimidazole derivatives and therapeutical compositions containing the same
JPS5395919A (en) New derivatives of amino acid
ES8507520A1 (en) Intermediates for clavulanic-acid derivatives.
UA16972A (en) Hydrochloride glycyl (2-benzoyl-4-bromo)anilide as anesthetic and antistress substance