SE8102254L - Foreningar, som hemmar kolesterolbiosyntes, och framstellning derav - Google Patents
Foreningar, som hemmar kolesterolbiosyntes, och framstellning deravInfo
- Publication number
- SE8102254L SE8102254L SE8102254A SE8102254A SE8102254L SE 8102254 L SE8102254 L SE 8102254L SE 8102254 A SE8102254 A SE 8102254A SE 8102254 A SE8102254 A SE 8102254A SE 8102254 L SE8102254 L SE 8102254L
- Authority
- SE
- Sweden
- Prior art keywords
- hydrogen atom
- associations
- preparation
- cholesterol biosynthesis
- esterifying
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/46—Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/80—Penicillium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/80—Penicillium
- C12R2001/82—Penicillium chrysogenum
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/80—Penicillium
- C12R2001/825—Penicillium notatum
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4600480A JPS56142236A (en) | 1980-04-08 | 1980-04-08 | Ml-236a and mb-530a derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
SE8102254L true SE8102254L (sv) | 1981-10-09 |
Family
ID=12734918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8102254A SE8102254L (sv) | 1980-04-08 | 1981-04-08 | Foreningar, som hemmar kolesterolbiosyntes, och framstellning derav |
Country Status (10)
Country | Link |
---|---|
JP (1) | JPS56142236A (sv) |
BE (1) | BE888332A (sv) |
DE (1) | DE3114242A1 (sv) |
DK (1) | DK158781A (sv) |
FI (1) | FI811080L (sv) |
FR (1) | FR2479809A1 (sv) |
GB (1) | GB2073199A (sv) |
IT (1) | IT1144327B (sv) |
NL (1) | NL8101749A (sv) |
SE (1) | SE8102254L (sv) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4450171A (en) * | 1980-08-05 | 1984-05-22 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
JPS5855443A (ja) * | 1981-09-25 | 1983-04-01 | Sankyo Co Ltd | オクタヒドロナフタリン誘導体およびその製造法 |
CA1327360C (en) * | 1983-11-14 | 1994-03-01 | William F. Hoffman | Oxo-analogs of mevinolin-like antihypercholesterolemic agents |
EP0164049B1 (en) * | 1984-06-04 | 1990-12-12 | Merck & Co. Inc. | Process for preparing hmg-coa reductase inhibtors with a 3,5-dihydroxypentanoate subunit |
EP0204287A3 (en) * | 1985-06-04 | 1987-07-01 | Merck & Co. Inc. | Process for the preparation of hmg-coa reductase inhibitors with a 3,5-dihydroxypentanoate subunit |
US4997848A (en) * | 1987-10-27 | 1991-03-05 | Sankyo Company, Limited | Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition |
US5250435A (en) * | 1991-06-04 | 1993-10-05 | Merck & Co., Inc. | Mutant strains of Aspergillus terreus for producing 7-[1,2,6,7,8,8a(R)-hexa-hydro-2(S),6(R)-dimethyl-8(S)-hydroxy-1(S)-naphthyl]-3(R),5(R)-dihydroxyheptanoic acid (triol acid),I) |
GB0003305D0 (en) | 2000-02-15 | 2000-04-05 | Zeneca Ltd | Pyrimidine derivatives |
TWI301483B (sv) | 2000-09-07 | 2008-10-01 | Kaneka Corp | |
SK242004A3 (en) | 2001-06-13 | 2004-06-08 | Ranbaxy Lab Ltd | Methyl analogs of simvastatin as novel HMG-CoA reductase inhibitors |
US8158362B2 (en) | 2005-03-30 | 2012-04-17 | Decode Genetics Ehf. | Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5612114B2 (sv) | 1974-06-07 | 1981-03-18 | ||
JPS5840476B2 (ja) * | 1975-05-12 | 1983-09-06 | 三共株式会社 | 新生理活性物質ml−236cおよびその製造法 |
JPS5817443B2 (ja) * | 1976-11-02 | 1983-04-07 | 三共株式会社 | Ml−236b金属塩を主成分とする高脂血症治療剤 |
JPS5925599B2 (ja) | 1979-02-20 | 1984-06-19 | 三共株式会社 | 新生理活性物質モナコリンkおよびその製造法 |
JPS55150898A (en) | 1979-05-11 | 1980-11-25 | Sankyo Co Ltd | Preparation of a new physiologically active substance mb-530b |
-
1980
- 1980-04-08 JP JP4600480A patent/JPS56142236A/ja active Pending
-
1981
- 1981-04-08 DK DK158781A patent/DK158781A/da not_active IP Right Cessation
- 1981-04-08 SE SE8102254A patent/SE8102254L/sv not_active Application Discontinuation
- 1981-04-08 FR FR8107028A patent/FR2479809A1/fr active Pending
- 1981-04-08 BE BE0/204416A patent/BE888332A/fr not_active IP Right Cessation
- 1981-04-08 DE DE3114242A patent/DE3114242A1/de not_active Withdrawn
- 1981-04-08 NL NL8101749A patent/NL8101749A/nl not_active Application Discontinuation
- 1981-04-08 GB GB8111061A patent/GB2073199A/en not_active Withdrawn
- 1981-04-08 IT IT67490/81A patent/IT1144327B/it active
- 1981-04-08 FI FI811080A patent/FI811080L/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BE888332A (fr) | 1981-10-08 |
NL8101749A (nl) | 1981-11-02 |
GB2073199A (en) | 1981-10-14 |
JPS56142236A (en) | 1981-11-06 |
FR2479809A1 (fr) | 1981-10-09 |
DK158781A (da) | 1981-10-09 |
IT1144327B (it) | 1986-10-29 |
IT8167490A0 (it) | 1981-04-08 |
FI811080L (fi) | 1981-10-09 |
DE3114242A1 (de) | 1982-06-16 |
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