SE8008090L - Forfarande for framstellning av sulfonylbensimidazoler - Google Patents

Forfarande for framstellning av sulfonylbensimidazoler

Info

Publication number
SE8008090L
SE8008090L SE8008090A SE8008090A SE8008090L SE 8008090 L SE8008090 L SE 8008090L SE 8008090 A SE8008090 A SE 8008090A SE 8008090 A SE8008090 A SE 8008090A SE 8008090 L SE8008090 L SE 8008090L
Authority
SE
Sweden
Prior art keywords
benzimidazoles
procedure
alkyl
compound
formula
Prior art date
Application number
SE8008090A
Other languages
English (en)
Other versions
SE433352B (sv
Inventor
C J Paget
J W Chamberlin
J H Wikel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/750,991 external-priority patent/US4118742A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SE8008090L publication Critical patent/SE8008090L/sv
Publication of SE433352B publication Critical patent/SE433352B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30Nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Claims (1)

Patentkrav R
1. Fbrfarande fbr framstallning av sulfenylbensimidazoler med den allmenna formeln SO2R dam R betecknar Cs-C.-alkyl, Cs-Cs-cykloalkyl eller -NRsRs, dar Rs och Sr oberoende ar varandra betecknar Cs-Cr-alkyl; och der R2 betecknar Sr dar Rs betecknar fenyl och R, betecknar varvid substituenten R2 Sr helagen i 5- eller f-stallningen, kannetecknat av att en fbrening med den all-manna formeln: dar R och Rs har ovan angivna betydelser, omsattes med en Cs-C7-alkylmagnesiumhalid eller med en Cs-C7.-alkyllitiumfbrening, varefter den resulterande fbreningen hydrclyseras till en fbrening med formeln: (tar R och Rs her de ovan angivna betydelserna och Sr beteck- narvarefter fbreningen med formeln III dehydra- tiseras. (I) (in)
SE8008090A 1976-12-15 1980-11-18 Forfarande for framstellning av sulfonylbensimidazoler SE433352B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/750,991 US4118742A (en) 1975-08-28 1976-12-15 Carbonyl-substituted 1-sulfonylbenzimidazoles

Publications (2)

Publication Number Publication Date
SE8008090L true SE8008090L (sv) 1980-11-18
SE433352B SE433352B (sv) 1984-05-21

Family

ID=25019992

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7701845A SE433351B (sv) 1976-12-15 1977-02-18 Forfarande for framstellning av sulfonylbensimidazoler
SE8008090A SE433352B (sv) 1976-12-15 1980-11-18 Forfarande for framstellning av sulfonylbensimidazoler

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7701845A SE433351B (sv) 1976-12-15 1977-02-18 Forfarande for framstellning av sulfonylbensimidazoler

Country Status (26)

Country Link
JP (1) JPS5377062A (sv)
AR (1) AR225397A1 (sv)
AT (1) AT347937B (sv)
AU (1) AU509374B2 (sv)
BE (1) BE851630A (sv)
BG (1) BG27742A3 (sv)
CA (1) CA1079737A (sv)
CH (1) CH630368A5 (sv)
CS (1) CS190339B2 (sv)
DD (1) DD129445A6 (sv)
DE (1) DE2706227A1 (sv)
DK (1) DK145645C (sv)
ES (1) ES456090A1 (sv)
FR (1) FR2374311A2 (sv)
GB (1) GB1568543A (sv)
GR (1) GR66420B (sv)
HU (1) HU175361B (sv)
IE (1) IE44863B1 (sv)
IL (1) IL51445A (sv)
MX (1) MX4495E (sv)
NL (1) NL187396C (sv)
PL (1) PL106887B1 (sv)
RO (1) RO71886A (sv)
SE (2) SE433351B (sv)
SU (1) SU680645A3 (sv)
ZA (1) ZA77691B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4420479A (en) * 1982-04-08 1983-12-13 Eli Lilly And Company Olefinic benzimidazoles, formulations, and antiviral methods
FR2593177B1 (fr) * 1986-01-20 1988-04-01 Novapharme Nouveaux benzimidazo
US5693661A (en) * 1995-06-07 1997-12-02 Eli Lilly And Company Anti-viral compounds
JP7226480B2 (ja) 2020-07-30 2023-02-21 大日本印刷株式会社 抗ウイルス性物品及び抗ウイルス性樹脂組成物
CN116209572A (zh) 2020-09-18 2023-06-02 大日本印刷株式会社 抗病毒性物品和抗病毒性树脂组合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51125078A (en) * 1974-07-01 1976-11-01 Lilly Co Eli Production of substituted 11sulphonylbenzimidazole

Also Published As

Publication number Publication date
SU680645A3 (ru) 1979-08-15
DK73277A (da) 1978-06-16
GB1568543A (en) 1980-05-29
AU509374B2 (en) 1980-05-08
DK145645B (da) 1983-01-10
ES456090A1 (es) 1978-05-16
PL106887B1 (pl) 1980-01-31
FR2374311B2 (sv) 1979-03-23
AR225397A1 (es) 1982-03-31
CH630368A5 (en) 1982-06-15
HU175361B (hu) 1980-07-28
JPS6229429B2 (sv) 1987-06-25
AU2244077A (en) 1978-08-24
PL196131A1 (pl) 1978-06-19
DE2706227A1 (de) 1978-06-22
SE433351B (sv) 1984-05-21
BE851630A (fr) 1977-08-18
AT347937B (de) 1979-01-25
MX4495E (es) 1982-05-21
JPS5377062A (en) 1978-07-08
SE7701845L (sv) 1978-06-16
IL51445A (en) 1981-02-27
FR2374311A2 (fr) 1978-07-13
NL187396B (nl) 1991-04-16
NL7701715A (nl) 1978-06-19
ATA111277A (de) 1978-06-15
DD129445A6 (de) 1978-01-18
IL51445A0 (en) 1977-04-29
RO71886A (ro) 1982-09-09
NL187396C (nl) 1991-09-16
CS190339B2 (en) 1979-05-31
DK145645C (da) 1983-07-11
IE44863L (en) 1978-06-15
DE2706227C2 (sv) 1989-09-07
CA1079737A (en) 1980-06-17
BG27742A3 (en) 1979-12-12
SE433352B (sv) 1984-05-21
GR66420B (sv) 1981-03-20
IE44863B1 (en) 1982-04-21
ZA77691B (en) 1978-09-27

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