SE8004873L - Forfarande for framstellning av oleandomycinderivat - Google Patents
Forfarande for framstellning av oleandomycinderivatInfo
- Publication number
- SE8004873L SE8004873L SE8004873A SE8004873A SE8004873L SE 8004873 L SE8004873 L SE 8004873L SE 8004873 A SE8004873 A SE 8004873A SE 8004873 A SE8004873 A SE 8004873A SE 8004873 L SE8004873 L SE 8004873L
- Authority
- SE
- Sweden
- Prior art keywords
- preparation
- procedure
- alkanoyl
- reed
- carbon atoms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Claims (2)
1. POrfarande for framstallning av en forening, son: her formeln:. 2 N(CH3)2 CH3 och de icke-toxiska syraadditionssalterna darav, van i X hetecknar gruppen R2CC112; R Sr vdte eller alkanoyl reed
2-3 kolatomer; Ri Sr vate eller alkanoyl med 2-3 kolatomer: och R2 5r vdte, tri-(15gre alkyl) -silyl rued 1-6 kolatomer vane alkylgrupp.eller alkanoyl reed 2-3 kolatomer, k anneteckn-t darav, att forening, som har formeln III ___ 0_„_..„.,, 0 OCH3 van i R, Ri och R2 tar oVan angiVen betydelse, bringas att reagera i ett reaktionsinert losningsmedel under kylning Oct i ett isvattenbad med fran 1 till 1,5 mol per mol oleandomycinderivat reed dimetylsulfoxoniummetylid, varefter blandningen f5r anta rumstemperatur under uppratthallande av kontakten mellan de reagerande substanserna tills reaktionen Sr VOsentligen fullstandig och, ndr s5 onskas, framstallning av syraadditicnssaltet. N(CR3)2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66346776A | 1976-03-03 | 1976-03-03 | |
| US70346476A | 1976-07-08 | 1976-07-08 | |
| US05/709,703 US4069379A (en) | 1976-07-08 | 1976-07-29 | Semi-synthetic oleandomycins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8004873L true SE8004873L (sv) | 1980-07-01 |
| SE436284B SE436284B (sv) | 1984-11-26 |
Family
ID=27418084
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7700786A SE436283B (sv) | 1976-03-03 | 1977-01-25 | Forfarande for framstellning av halvsyntetiska oleandomycin-derivat och icke-toxiska syraadditionssalter derav |
| SE8004873A SE436284B (sv) | 1976-03-03 | 1980-07-01 | Forfarande for framstellning av cyklopropyloleandomyciner och icke-toxiska syraadditionssalter derav |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7700786A SE436283B (sv) | 1976-03-03 | 1977-01-25 | Forfarande for framstellning av halvsyntetiska oleandomycin-derivat och icke-toxiska syraadditionssalter derav |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS52106880A (sv) |
| AR (1) | AR212524A1 (sv) |
| AT (1) | AT347586B (sv) |
| BG (2) | BG27913A3 (sv) |
| CA (1) | CA1069503A (sv) |
| DD (1) | DD129789A5 (sv) |
| DE (2) | DE2660089C2 (sv) |
| DK (1) | DK146778C (sv) |
| ES (1) | ES455805A1 (sv) |
| FI (1) | FI770440A (sv) |
| FR (1) | FR2342989A1 (sv) |
| GB (1) | GB1567390A (sv) |
| IE (1) | IE44509B1 (sv) |
| IL (1) | IL51361A (sv) |
| LU (1) | LU76764A1 (sv) |
| NL (1) | NL170151C (sv) |
| NZ (1) | NZ183235A (sv) |
| PH (1) | PH13171A (sv) |
| PT (1) | PT66157B (sv) |
| RO (2) | RO72560A (sv) |
| SE (2) | SE436283B (sv) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166901A (en) * | 1978-01-03 | 1979-09-04 | Pfizer Inc. | 4"-Deoxy-4"-arylglyoxamido- and aroylthioformamido derivatives of oleandomycin and its esters |
| US4180654A (en) * | 1978-01-03 | 1979-12-25 | Pfizer Inc. | 4"-Deoxy-4"-acylamido derivatives of oleandomycin, erythromycin and erythromycin carbonate |
-
1976
- 1976-11-23 IE IE2578/76A patent/IE44509B1/en unknown
- 1976-12-02 DE DE2660089A patent/DE2660089C2/de not_active Expired
- 1976-12-02 DE DE2654627A patent/DE2654627C3/de not_active Expired
-
1977
- 1977-01-25 SE SE7700786A patent/SE436283B/sv unknown
- 1977-01-31 IL IL51361A patent/IL51361A/xx unknown
- 1977-02-01 AT AT62777A patent/AT347586B/de not_active IP Right Cessation
- 1977-02-02 NZ NZ183235A patent/NZ183235A/xx unknown
- 1977-02-02 PH PH19411A patent/PH13171A/en unknown
- 1977-02-04 PT PT66157A patent/PT66157B/pt unknown
- 1977-02-09 FR FR7703604A patent/FR2342989A1/fr active Granted
- 1977-02-09 CA CA271,457A patent/CA1069503A/en not_active Expired
- 1977-02-10 NL NLAANVRAGE7701401,A patent/NL170151C/xx not_active IP Right Cessation
- 1977-02-10 ES ES455805A patent/ES455805A1/es not_active Expired
- 1977-02-10 FI FI770440A patent/FI770440A/fi not_active Application Discontinuation
- 1977-02-10 JP JP1403577A patent/JPS52106880A/ja active Granted
- 1977-02-10 DK DK57177A patent/DK146778C/da not_active IP Right Cessation
- 1977-02-11 LU LU76764A patent/LU76764A1/xx unknown
- 1977-02-11 AR AR266519A patent/AR212524A1/es active
- 1977-02-11 GB GB5755/77A patent/GB1567390A/en not_active Expired
- 1977-02-23 RO RO7789496A patent/RO72560A/ro unknown
- 1977-02-23 RO RO7797127A patent/RO76882A/ro unknown
- 1977-02-25 BG BG7735526A patent/BG27913A3/xx unknown
- 1977-02-25 BG BG7736454A patent/BG27914A4/xx unknown
- 1977-02-28 DD DD7700197598A patent/DD129789A5/xx unknown
-
1980
- 1980-07-01 SE SE8004873A patent/SE436284B/sv unknown
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