IE44509L - Semi-synthetic oleandomycins - Google Patents

Semi-synthetic oleandomycins

Info

Publication number
IE44509L
IE44509L IE762578A IE257876A IE44509L IE 44509 L IE44509 L IE 44509L IE 762578 A IE762578 A IE 762578A IE 257876 A IE257876 A IE 257876A IE 44509 L IE44509 L IE 44509L
Authority
IE
Ireland
Prior art keywords
compounds
semi
oleandomycins
methylene
synthetic
Prior art date
Application number
IE762578A
Other versions
IE44509B1 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/709,703 external-priority patent/US4069379A/en
Application filed by Pfizer filed Critical Pfizer
Publication of IE44509L publication Critical patent/IE44509L/en
Publication of IE44509B1 publication Critical patent/IE44509B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Disclosed herein is a novel series of semi-synthetic oleandomycins having an exocyclic methylene or a cyclopropyl group at the C8 position. Processes for preparing the methylene compounds from the natural oleandomycins and the cyclopropyl compounds from the methylene compounds are also disclosed. The above oleandomycin compounds are effective in inhibiting the growth of microorganism, especially Gram-positive microorganism. [CA1069503A]
IE2578/76A 1976-03-03 1976-11-23 Semi-synthetic oleandomycins IE44509B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66346776A 1976-03-03 1976-03-03
US70346476A 1976-07-08 1976-07-08
US05/709,703 US4069379A (en) 1976-07-08 1976-07-29 Semi-synthetic oleandomycins

Publications (2)

Publication Number Publication Date
IE44509L true IE44509L (en) 1977-09-03
IE44509B1 IE44509B1 (en) 1981-12-30

Family

ID=27418084

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2578/76A IE44509B1 (en) 1976-03-03 1976-11-23 Semi-synthetic oleandomycins

Country Status (21)

Country Link
JP (1) JPS52106880A (en)
AR (1) AR212524A1 (en)
AT (1) AT347586B (en)
BG (2) BG27914A4 (en)
CA (1) CA1069503A (en)
DD (1) DD129789A5 (en)
DE (2) DE2660089C2 (en)
DK (1) DK146778C (en)
ES (1) ES455805A1 (en)
FI (1) FI770440A (en)
FR (1) FR2342989A1 (en)
GB (1) GB1567390A (en)
IE (1) IE44509B1 (en)
IL (1) IL51361A (en)
LU (1) LU76764A1 (en)
NL (1) NL170151C (en)
NZ (1) NZ183235A (en)
PH (1) PH13171A (en)
PT (1) PT66157B (en)
RO (2) RO76882A (en)
SE (2) SE436283B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4180654A (en) * 1978-01-03 1979-12-25 Pfizer Inc. 4"-Deoxy-4"-acylamido derivatives of oleandomycin, erythromycin and erythromycin carbonate
US4166901A (en) * 1978-01-03 1979-09-04 Pfizer Inc. 4"-Deoxy-4"-arylglyoxamido- and aroylthioformamido derivatives of oleandomycin and its esters

Also Published As

Publication number Publication date
SE8004873L (en) 1980-07-01
SE436284B (en) 1984-11-26
IE44509B1 (en) 1981-12-30
DD129789A5 (en) 1978-02-08
ES455805A1 (en) 1978-04-01
LU76764A1 (en) 1977-08-19
DK57177A (en) 1977-09-04
DE2654627B2 (en) 1979-11-29
NL7701401A (en) 1977-09-06
NL170151C (en) 1982-10-01
RO72560A (en) 1983-07-07
DK146778B (en) 1984-01-02
DK146778C (en) 1984-06-12
FR2342989B1 (en) 1980-07-04
PH13171A (en) 1980-01-08
IL51361A0 (en) 1977-03-31
CA1069503A (en) 1980-01-08
JPS52106880A (en) 1977-09-07
RO76882A (en) 1981-08-17
DE2660089B1 (en) 1980-03-20
AT347586B (en) 1979-01-10
AU2200677A (en) 1978-05-18
DE2660089C2 (en) 1980-11-06
PT66157A (en) 1977-03-01
DE2654627A1 (en) 1977-09-08
ATA62777A (en) 1978-05-15
RO72560B (en) 1983-06-30
FI770440A (en) 1977-09-04
AR212524A1 (en) 1978-07-31
GB1567390A (en) 1980-05-14
SE436283B (en) 1984-11-26
NZ183235A (en) 1978-11-13
BG27914A4 (en) 1980-01-15
NL170151B (en) 1982-05-03
PT66157B (en) 1978-07-10
FR2342989A1 (en) 1977-09-30
IL51361A (en) 1979-10-31
JPS552437B2 (en) 1980-01-19
DE2654627C3 (en) 1980-07-31
BG27913A3 (en) 1980-01-15
SE7700786L (en) 1977-10-03

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