SE7910336L - 3-oximer av d-17 -etynyl-19-nortesteronestrar och forfarande for framstellning derav - Google Patents

3-oximer av d-17 -etynyl-19-nortesteronestrar och forfarande for framstellning derav

Info

Publication number
SE7910336L
SE7910336L SE7910336A SE7910336A SE7910336L SE 7910336 L SE7910336 L SE 7910336L SE 7910336 A SE7910336 A SE 7910336A SE 7910336 A SE7910336 A SE 7910336A SE 7910336 L SE7910336 L SE 7910336L
Authority
SE
Sweden
Prior art keywords
ethynyl
esters
nortesterone
oximer
procedures
Prior art date
Application number
SE7910336A
Other languages
English (en)
Other versions
SE445458B (sv
Inventor
A P Shroff
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of SE7910336L publication Critical patent/SE7910336L/sv
Publication of SE445458B publication Critical patent/SE445458B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016—Oximes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Fertilizers (AREA)

Claims (2)

Patentkrav
1. Komposition till anvdndning aid undertryckandet av frultbarket, kdnnetecknad av en fbreningiD-serien med formeln: ..CECCH HON och ett bstrogent hormon, varvid R betecknar al anoyl med 2-10 kolatomer och R' betecknar metyl eller etyl.
2. 'Composition cnligt krav 1, kdnnetecknad ddrav, att R betecknar acetyl, 0 betecknar etyl och let ostrogena hormonet r etinylostradiol, 17,-Ostradiol, mestranol eller 170X-ctiny105tradicl-5-cyklopentyleter.
SE7910336A 1975-07-24 1979-12-14 Komposition innehallande en progestational steroid i d-serien och en ostrogen SE445458B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59896675A 1975-07-24 1975-07-24
US05/652,000 US4027019A (en) 1975-07-24 1976-01-23 3-Oximes of D-17α-ethynyl-19-nortestosterone esters and method

Publications (2)

Publication Number Publication Date
SE7910336L true SE7910336L (sv) 1979-12-14
SE445458B SE445458B (sv) 1986-06-23

Family

ID=27083202

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7608407A SE421800B (sv) 1975-07-24 1976-07-23 3-oxim av d-17alfa-etynyl-19-nortestosteronacetat till anvendning for undertryckande av fruktbarhet
SE7910336A SE445458B (sv) 1975-07-24 1979-12-14 Komposition innehallande en progestational steroid i d-serien och en ostrogen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7608407A SE421800B (sv) 1975-07-24 1976-07-23 3-oxim av d-17alfa-etynyl-19-nortestosteronacetat till anvendning for undertryckande av fruktbarhet

Country Status (22)

Country Link
US (1) US4027019A (sv)
JP (1) JPS5214760A (sv)
AT (1) AT350748B (sv)
AU (1) AU501808B2 (sv)
CA (1) CA1072948A (sv)
CH (1) CH599249A5 (sv)
DE (2) DE2661002C2 (sv)
DK (1) DK145610C (sv)
ES (1) ES450108A1 (sv)
FI (1) FI55036C (sv)
FR (1) FR2318645A1 (sv)
GB (1) GB1557197A (sv)
IE (1) IE43581B1 (sv)
IL (1) IL50103A (sv)
MX (1) MX3417E (sv)
NL (1) NL192206C (sv)
NO (1) NO143350C (sv)
NZ (1) NZ181130A (sv)
PH (1) PH12003A (sv)
PT (1) PT65402B (sv)
SE (2) SE421800B (sv)
YU (1) YU39968B (sv)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507290A (en) * 1981-04-07 1985-03-26 World Health Organization Esters of 17 α-ethynyl 19-nor-testosterone and 17 α-ethynyl-18-homo-19-nor-testosterone and pharmaceutical compositions containing the same
GB8313921D0 (en) * 1983-05-19 1983-06-22 World Health Org Contraceptive compositions
WO1993013122A1 (de) * 1991-12-22 1993-07-08 Schering Aktiengesellschaft 3-methylsulfonylhydrazono- und 3-oxyimino-steroide, ein verfahren zu deren herstellung, diese steroide enthaltende pharmazeutische präparate sowie ihre verwendung zur herstellung von arzneimitteln
US7459445B2 (en) * 2000-03-10 2008-12-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and topical pharmaceutical formulations of the same
US6855703B1 (en) 2000-03-10 2005-02-15 Endeavor Pharmaceuticals Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US6660726B2 (en) 2000-03-10 2003-12-09 Endeavor Pharmaceuticals Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
US7989436B2 (en) * 2003-07-23 2011-08-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and pharmaceutical formulations comprising the same
WO2002062391A2 (en) * 2001-02-02 2002-08-15 Pharmacia Corporation Method of using a cyclooxygenase-2 inhibitor and sex steroids as a combination therapy for the treatment and prevention of dismenorrhea
US6992075B2 (en) * 2003-04-04 2006-01-31 Barr Laboratories, Inc. C(14) estrogenic compounds
JP2006522833A (ja) * 2003-04-11 2006-10-05 バー・ラボラトリーズ，インコーポレイテッド エストロゲンおよびプロゲスチンの投与法
AR039733A1 (es) * 2003-06-25 2005-03-09 Gador Sa Proceso para la obtencion de norelgestromin en distintas relaciones de los isomeros e y z
HUP0301981A2 (hu) * 2003-06-30 2005-04-28 Richter Gedeon Vegyészeti Gyár Rt. Tiszta d-(17alfa)-13-etil-17-hidroxi-18,19-dinor-pregn-4-én-20-in-3-on-3E- és 3Z-oxim izomerek, valamint eljárás az izomer keverékek és a tiszta izomerek előállítására
HUP0301982A2 (hu) * 2003-06-30 2005-04-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás nagy tisztaságú d-(17alfa)-13-etil-17-hidroxi-18,19-dinor-pregn-4-én-20-in-3-on-oxim előállítására
US7816546B2 (en) * 2003-06-30 2010-10-19 Richter Gedeon Vegyeszeti Gyar Rt. Process for the synthesis of high purity d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-oxime
EP1778716A1 (en) * 2004-08-12 2007-05-02 Sicor Inc. Process for the preparation of 3-oximino steroids
CA2601773A1 (en) * 2005-02-03 2006-08-10 Duramed Pharmaceuticals, Inc. Compositions of unconjugated estrogens and methods for their use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1493161B2 (de) * 1951-01-28 1973-08-30 17alpha-aethinyl-18-methyl-19nortestosteronester, verfahren zu ihrer herstellung und diese enthaltendes mittel
US3780073A (en) * 1966-07-06 1973-12-18 Ortho Pharma Corp 3-oximes of 19-nortestosterone esters
US3532689A (en) * 1967-04-20 1970-10-06 Ortho Pharma Corp 3-oxime and 3-oxime esters of 19-nortestosterone
NL7306609A (sv) * 1972-05-26 1973-11-28
US3912768A (en) * 1972-09-26 1975-10-14 Warner Lambert Co Norethindrone O-alkyloximes

Also Published As

Publication number Publication date
NL7608210A (nl) 1977-01-26
ES450108A1 (es) 1977-11-16
NZ181130A (en) 1984-07-06
AU1535776A (en) 1978-01-05
SE421800B (sv) 1982-02-01
PT65402B (en) 1979-06-09
GB1557197A (en) 1979-12-05
FI762116A (sv) 1977-01-25
DE2661002A1 (sv) 1985-05-02
PT65402A (en) 1976-08-01
YU173376A (en) 1982-08-31
SE445458B (sv) 1986-06-23
FR2318645B1 (sv) 1978-11-17
SE7608407L (sv) 1977-01-25
DK335876A (da) 1977-01-25
JPS624400B2 (sv) 1987-01-30
PH12003A (en) 1978-10-06
AT350748B (de) 1979-06-11
CA1072948A (en) 1980-03-04
NO143350C (no) 1981-01-28
DE2633210A1 (de) 1977-02-17
JPS5214760A (en) 1977-02-03
IL50103A (en) 1979-11-30
DE2661002C2 (sv) 1988-03-17
MX3417E (es) 1980-11-13
NO762583L (sv) 1977-01-25
FI55036B (fi) 1979-01-31
US4027019A (en) 1977-05-31
NL192206C (nl) 1997-03-04
NO143350B (no) 1980-10-13
ATA543976A (de) 1978-11-15
YU39968B (en) 1985-06-30
DK145610C (da) 1983-08-01
DK145610B (da) 1982-12-27
CH599249A5 (sv) 1978-05-31
IL50103A0 (en) 1976-09-30
FR2318645A1 (fr) 1977-02-18
FI55036C (fi) 1979-05-10
DE2633210C2 (sv) 1987-04-09
NL192206B (nl) 1996-11-01
AU501808B2 (en) 1979-06-28
IE43581L (en) 1977-01-24
IE43581B1 (en) 1981-04-08

Similar Documents

Publication Publication Date Title
SE7910336L (sv) 3-oximer av d-17 -etynyl-19-nortesteronestrar och forfarande for framstellning derav
ES470408A1 (es) Procedimiento para la preparacion de un compuesto tetraci- clico
MX9203239A (es) Derivados de 1-(dihidroxifenil)-2-amino-etanol y composiciones farmaceuticas que los contienen.
JPS5432460A (en) Cycloalkylidenemethylphenylacetic acid derivative and their preparation
ES468807A1 (es) Procedimiento para la preparacion de nuevos n-heterociclos n-fenilsubstituidos
FR2384783A1 (fr) Derives heteromonocycliques etheterobicycliques de l'acide 7 actylamido-3-cephem-4-carboxylique insature, procedes de preparation de ceux-ci, et utilisation en therapeutique
FR2445329A1 (fr) Derives du 11-bromo-14-oxo-15-hydroxy-imino-e-homo-eburnane, leur preparation et leur utilisation comme medicament
ES454086A1 (es) Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-norosimorfona nuevas.
IE45178L (en) Phenothiazine derivatives
ES8104222A1 (es) Un procedimiento para la preparacion de derivados del acido 7-oxo-1-aza-biciclo (3,2,0) hept-2-en-2-carboxilico
JPS5770820A (en) Immunoregulating agent
JPS5419987A (en) Pyridazinone derivative and its preparation
JPS5334764A (en) Preparation of diterpene derivatives and their preparation
JPS5414983A (en) Tunicamine derivative and its preparation
ATE25661T1 (de) Aphidicolanderivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen.
IE790924L (en) 1,3-benzodioxin derivatives
FI803088A (fi) 10-bromsandwicin och 10-bromisosandwicin foerfarande foer deras framstaellning samt deras anvaendning
JPS5427578A (en) 1-carboxyalkylcarbamoyl-5-fluorouracil derivatives and their preparation
ES390920A1 (es) Procedimiento para la preparacion de 4,5 alfa - oxido - gufa-20,22-dienolid-3-(ramnosido 2'83' - dialcohilortocarbo-natos).
JPS545924A (en) Derivative of butylaldeyde and its preparation
JPS5432482A (en) 3,4-dihydrocarbostyril derivatives and bactericides containing the same as active agnet for agricultural and horticultural uses
ES8101591A1 (es) Un procedimiento para la preparacion de analogos de cefalos-porina
JPS53112880A (en) Dibromodihydropyran derivative and its preparation
JPS5671080A (en) Novel mandelic tetrazol-5-ylthiol ester and its preparation
ES479233A1 (es) Procedimiento para la obtencion de derivados de antraquinona.

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7910336-2

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7910336-2

Format of ref document f/p: F