SE7909751L - 4,1-bensoxazepiner och tia-analoger derav - Google Patents
4,1-bensoxazepiner och tia-analoger deravInfo
- Publication number
- SE7909751L SE7909751L SE7909751A SE7909751A SE7909751L SE 7909751 L SE7909751 L SE 7909751L SE 7909751 A SE7909751 A SE 7909751A SE 7909751 A SE7909751 A SE 7909751A SE 7909751 L SE7909751 L SE 7909751L
- Authority
- SE
- Sweden
- Prior art keywords
- hydrogen
- image
- benzoxazepines
- alkyl
- analogs
- Prior art date
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229910052717 sulfur Chemical group 0.000 abstract 2
- 239000011593 sulfur Chemical group 0.000 abstract 2
- YAVSXFRYNGAFRN-UHFFFAOYSA-N 4,1-benzoxazepine Chemical class O1C=CN=C2C=CC=CC2=C1 YAVSXFRYNGAFRN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 241000534944 Thia Species 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 239000003576 central nervous system agent Substances 0.000 abstract 1
- 125000004984 dialkylaminoalkoxy group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/36—Seven-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14694978A JPS5572177A (en) | 1978-11-27 | 1978-11-27 | 4,1-benzoxazepine or 4,1-benzothiazepine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7909751L true SE7909751L (sv) | 1980-05-28 |
Family
ID=15419209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7909751A SE7909751L (sv) | 1978-11-27 | 1979-11-26 | 4,1-bensoxazepiner och tia-analoger derav |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US4297280A (en, 2012) |
| JP (1) | JPS5572177A (en, 2012) |
| AR (1) | AR227879A1 (en, 2012) |
| AU (1) | AU533517B2 (en, 2012) |
| BE (1) | BE880282A (en, 2012) |
| CA (1) | CA1127639A (en, 2012) |
| CH (1) | CH642647A5 (en, 2012) |
| DD (1) | DD147360A5 (en, 2012) |
| DE (1) | DE2947773A1 (en, 2012) |
| DK (1) | DK500179A (en, 2012) |
| ES (4) | ES8102106A1 (en, 2012) |
| FR (1) | FR2442239A1 (en, 2012) |
| GB (1) | GB2046729B (en, 2012) |
| HU (1) | HU179589B (en, 2012) |
| IT (1) | IT1165246B (en, 2012) |
| MX (1) | MX6217E (en, 2012) |
| NL (1) | NL7908596A (en, 2012) |
| NZ (1) | NZ192092A (en, 2012) |
| SE (1) | SE7909751L (en, 2012) |
| SU (2) | SU936815A3 (en, 2012) |
| ZA (1) | ZA796040B (en, 2012) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5759893A (en) * | 1980-09-29 | 1982-04-10 | Shionogi & Co Ltd | 4,1-benzoxazepin derivative |
| US4374842A (en) * | 1980-04-18 | 1983-02-22 | Shionogi & Co., Ltd. | 4,1-Benzoxazepines and compositions |
| CA1211437A (en) * | 1981-08-12 | 1986-09-16 | Rene Borer | Benzazepines |
| US4590187A (en) * | 1983-11-17 | 1986-05-20 | The Upjohn Company | Phospholipase A2 inhibition using 4,1-benzoxazepine-2-(3H)-ones |
| US4897392A (en) * | 1989-07-03 | 1990-01-30 | Hoechst-Roussel Pharmaceuticals, Inc. | 4H-indolo(1,2-d)(1,2,4)triazolo(4,3-A)(1,4)benzodiazepines |
| EP0567026B1 (en) * | 1992-04-20 | 2003-03-26 | Takeda Chemical Industries, Ltd. | 4,1-Benzoxazepin derivatives as squalene synthase inhibitors and their use in the treatment of hypercholesteremia and as fungicides |
| RU2170732C2 (ru) * | 1993-04-19 | 2001-07-20 | Такеда Кемикал Индастриз, Лтд. | Производные 4,1-бензоксазепина |
| HUT74682A (en) * | 1993-12-29 | 1997-01-28 | Pfizer | Diazabicyclic neurokinin antagonists and pharmaceutical compositions containing them |
| US5552399A (en) * | 1994-11-02 | 1996-09-03 | Janssen Pharmaceutica N.V. | Substituted tetracyclic azepine derivatives |
| RU2161159C2 (ru) * | 1994-11-02 | 2000-12-27 | Жансен Фармасетика Н.В. | Замещенные тетрациклические производные оксазепина и тиазепина, способ их получения, композиция, обладающая антипсихотической активностью, и способ ее получения |
| US6063921A (en) | 1997-11-20 | 2000-05-16 | Pharm-Eco Laboratories, Inc. | Synthesis of 11-aryl-5,6-dihydro-11H-dibenz[b,e]azepines |
| RU2266906C1 (ru) * | 2004-04-29 | 2005-12-27 | Общество с ограниченной ответственностью "Исследовательский Институт Химического Разнообразия" (ООО "Исследовательский Институт Химического Разнообразия") | Анелированные карбамоилазагетероциклы, способы их получения (варианты), фармацевтическая композиция, фокусированная библиотека |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1090611A (en) * | 1963-05-22 | 1967-11-08 | Lepetit Spa | 4,1-benzoxazepine derivatives |
| DE1545639A1 (de) * | 1965-11-19 | 1969-08-07 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von Derivaten des 3,5-Dihydro-4,1-Benzothiazepin-2[1 H]-ons |
| BE793629A (fr) * | 1972-01-03 | 1973-07-03 | Upjohn Co | Nouveaux derives de benzodiazepines et leur preparation |
| JPS5084590A (en, 2012) * | 1973-11-28 | 1975-07-08 | ||
| US4000151A (en) * | 1974-09-11 | 1976-12-28 | The Upjohn Company | Triazolyl benzophenone compounds |
| US3933816A (en) * | 1974-09-12 | 1976-01-20 | The Upjohn Company | 3-(Substituted aminomethyl)-7-substituted-3,5-dihydro-as-triazino[4,3-a][1,5]benzodiazepines |
| US3966756A (en) * | 1975-04-07 | 1976-06-29 | American Cyanamid Company | Substituted dibenzo[b,f]tetrazolo[1,5-d][1,4]-oxazepines |
| US4246270A (en) * | 1976-05-26 | 1981-01-20 | E. I. Du Pont De Nemours And Company | 3-Fluorobenzodiazepines and compositions and uses thereof |
| US4207322A (en) * | 1975-11-04 | 1980-06-10 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler | 6-Aryl-s-triazolo-(4,3-alpha)-pyrido-(2,3-f)-(1,4)-diazepines |
| US4180668A (en) * | 1977-06-08 | 1979-12-25 | The Upjohn Company | Piperidino-4H-s-triazolo[4,3-a][1,4]benzodiazepines |
| JPS54119499A (en) * | 1978-03-09 | 1979-09-17 | Shionogi & Co Ltd | Triazolobenzodiazepin derivative |
-
1978
- 1978-11-27 JP JP14694978A patent/JPS5572177A/ja active Granted
-
1979
- 1979-11-02 CA CA339,060A patent/CA1127639A/en not_active Expired
- 1979-11-06 US US06/091,814 patent/US4297280A/en not_active Expired - Lifetime
- 1979-11-09 ZA ZA00796040A patent/ZA796040B/xx unknown
- 1979-11-12 NZ NZ192092A patent/NZ192092A/en unknown
- 1979-11-20 AU AU52993/79A patent/AU533517B2/en not_active Ceased
- 1979-11-22 CH CH1042379A patent/CH642647A5/de not_active IP Right Cessation
- 1979-11-23 DK DK500179A patent/DK500179A/da not_active Application Discontinuation
- 1979-11-26 HU HU79SI1731A patent/HU179589B/hu unknown
- 1979-11-26 IT IT7969279A patent/IT1165246B/it active
- 1979-11-26 ES ES486328A patent/ES8102106A1/es not_active Expired
- 1979-11-26 FR FR7929096A patent/FR2442239A1/fr active Granted
- 1979-11-26 SE SE7909751A patent/SE7909751L/xx not_active Application Discontinuation
- 1979-11-27 SU SU792847003A patent/SU936815A3/ru active
- 1979-11-27 DD DD79217162A patent/DD147360A5/de unknown
- 1979-11-27 MX MX798501U patent/MX6217E/es unknown
- 1979-11-27 GB GB7940898A patent/GB2046729B/en not_active Expired
- 1979-11-27 DE DE19792947773 patent/DE2947773A1/de not_active Withdrawn
- 1979-11-27 NL NL7908596A patent/NL7908596A/xx not_active Application Discontinuation
- 1979-11-27 BE BE0/198307A patent/BE880282A/fr not_active IP Right Cessation
- 1979-11-27 AR AR279045A patent/AR227879A1/es active
-
1980
- 1980-07-28 ES ES493759A patent/ES8106729A1/es not_active Expired
- 1980-07-28 ES ES493760A patent/ES493760A0/es active Granted
- 1980-07-28 ES ES493761A patent/ES493761A0/es active Granted
- 1980-12-04 SU SU803211176A patent/SU1005660A3/ru active
-
1981
- 1981-06-23 US US06/276,632 patent/US4341704A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES486328A0 (es) | 1980-12-16 |
| SU1005660A3 (ru) | 1983-03-15 |
| IT1165246B (it) | 1987-04-22 |
| BE880282A (fr) | 1980-03-17 |
| NL7908596A (nl) | 1980-05-29 |
| FR2442239A1 (fr) | 1980-06-20 |
| DD147360A5 (de) | 1981-04-01 |
| GB2046729B (en) | 1983-01-26 |
| AU5299379A (en) | 1980-05-29 |
| MX6217E (es) | 1984-12-21 |
| FR2442239B1 (en, 2012) | 1983-07-01 |
| SU936815A3 (ru) | 1982-06-15 |
| ES8106730A1 (es) | 1981-08-01 |
| IT7969279A0 (it) | 1979-11-26 |
| DE2947773A1 (de) | 1980-06-04 |
| ES8106731A1 (es) | 1981-08-01 |
| ES493761A0 (es) | 1981-08-01 |
| ES493759A0 (es) | 1981-08-01 |
| GB2046729A (en) | 1980-11-19 |
| AU533517B2 (en) | 1983-12-01 |
| DK500179A (da) | 1980-05-28 |
| JPS6231719B2 (en, 2012) | 1987-07-09 |
| HU179589B (en) | 1982-11-29 |
| ES8102106A1 (es) | 1980-12-16 |
| ZA796040B (en) | 1980-10-29 |
| AR227879A1 (es) | 1982-12-30 |
| US4297280A (en) | 1981-10-27 |
| CH642647A5 (de) | 1984-04-30 |
| JPS5572177A (en) | 1980-05-30 |
| US4341704A (en) | 1982-07-27 |
| CA1127639A (en) | 1982-07-13 |
| NZ192092A (en) | 1984-07-31 |
| ES8106729A1 (es) | 1981-08-01 |
| ES493760A0 (es) | 1981-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 7909751-5 |