JPS5759893A - 4,1-benzoxazepin derivative - Google Patents
4,1-benzoxazepin derivativeInfo
- Publication number
- JPS5759893A JPS5759893A JP55136646A JP13664680A JPS5759893A JP S5759893 A JPS5759893 A JP S5759893A JP 55136646 A JP55136646 A JP 55136646A JP 13664680 A JP13664680 A JP 13664680A JP S5759893 A JPS5759893 A JP S5759893A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- alkyl
- benzoxazepin
- formulai
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A compound of formulaI[R' is H, halogen, nitro; R2 is H, halogen, trifluoromethyl; -A-B- is formula IV W formula VI (R3 is alkyl, dialkylaminoalkyl; R4 is alkyl, alkylthio)]and its pharmaceutically permissible acid adduct.
EXAMPLE: 8-Chloro-6-(2-chlorophenyl)-1-oxo-1H,4H,6H-[1,2,4]oxadiazolo[4,3-a] [4,1]benzoxazepin.
USE: Psycotropic such as antianxiety agent, tranquilizer, anticonvulsant, hypnotic.
PREPARATION: A compound of formula II reacts with hydroxylamine in an inert solvent to form an oxime of formula III, which is made to react with an alkyl halocarbonate such as methyl chlorocarbonate in the presence of a hase such as triethylamine to give the compound of formula Ia where -A-B- is formula IV in formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55136646A JPS5759893A (en) | 1980-09-29 | 1980-09-29 | 4,1-benzoxazepin derivative |
US06/250,299 US4374842A (en) | 1980-04-18 | 1981-04-02 | 4,1-Benzoxazepines and compositions |
CH253081A CH645637A5 (en) | 1980-04-18 | 1981-04-15 | 4,1-BENZOXAZEPINE. |
FR8107700A FR2480751A1 (en) | 1980-04-18 | 1981-04-16 | 4,1-BENZOXAZEPINES AND THEIR USE AS PHARMACEUTICAL PRODUCTS FOR THE CENTRAL NERVOUS SYSTEM |
DE19813115552 DE3115552A1 (en) | 1980-04-18 | 1981-04-16 | 4.1-BENZOXAZEPINE AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
AU69623/81A AU544637B2 (en) | 1980-04-18 | 1981-04-16 | 4,1-benzoxazepines |
IT67533/81A IT1146746B (en) | 1980-04-18 | 1981-04-17 | COMPOUND OF THE CATEGORY OF BENZOSSAZEPIN USABLE AS AN ACTIVE DRUG ON THE CENTRAL NERVOUS SYSTEM |
GB8112387A GB2075012B (en) | 1980-04-18 | 1981-04-21 | 4,1-benzoxazepines |
US06/397,855 US4476133A (en) | 1980-04-18 | 1982-07-13 | Triazolo-4,1-benzoxazepines having CNS activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55136646A JPS5759893A (en) | 1980-09-29 | 1980-09-29 | 4,1-benzoxazepin derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5759893A true JPS5759893A (en) | 1982-04-10 |
JPH029593B2 JPH029593B2 (en) | 1990-03-02 |
Family
ID=15180178
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55136646A Granted JPS5759893A (en) | 1980-04-18 | 1980-09-29 | 4,1-benzoxazepin derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5759893A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5572177A (en) * | 1978-11-27 | 1980-05-30 | Shionogi & Co Ltd | 4,1-benzoxazepine or 4,1-benzothiazepine |
-
1980
- 1980-09-29 JP JP55136646A patent/JPS5759893A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5572177A (en) * | 1978-11-27 | 1980-05-30 | Shionogi & Co Ltd | 4,1-benzoxazepine or 4,1-benzothiazepine |
Also Published As
Publication number | Publication date |
---|---|
JPH029593B2 (en) | 1990-03-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8103053A1 (en) | 2-Imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same. | |
JPS5759893A (en) | 4,1-benzoxazepin derivative | |
JPS5659778A (en) | Dimethylthienopyrimidione derivative | |
IE56001B1 (en) | 1-arylcyclobutylmethylamine compounds | |
JPS5572177A (en) | 4,1-benzoxazepine or 4,1-benzothiazepine | |
IE780403L (en) | Antiphlogistic compositions | |
JPS57212188A (en) | Imidazobenzoxazine derivative and its preparation | |
IE791036L (en) | Thienopyridines and furanopyridines | |
JPS5564592A (en) | Thiazolo 3, 2-a pyrimidine derivative, its preparation, and drug comprising it | |
IE42711L (en) | THIENO (3,2-c) PYRIDINE DERIVATIVES | |
JPS53130661A (en) | Benzilidene ketone compound, its preparation, and fungicide containing the same | |
JPS5782391A (en) | Thiopyrano(4,5-b)pyridin-2-one derivative | |
IE792068L (en) | 1, 2, 4-triazoles. | |
IE812941L (en) | Imidazole derivatives | |
JPS5549386A (en) | Heterocyclic compound and its acid addition salt | |
JPS554334A (en) | Pyranopyrazole derivative | |
JPS532449A (en) | Preparation of 2-substituted propionic acid derivatives | |
JPS57175193A (en) | Preparation of triazolopyrimidine derivative | |
IE45587L (en) | Diazepinoheterocyclic compounds | |
JPS5562092A (en) | Antiphlogistic agent containing thiazolo 3,2-a pyrimidine derivative | |
JPS5566593A (en) | Thiazolo 3,2-a pyrimidine-1-oxide derivative, its preparation, and drug containing the same | |
JPS55104274A (en) | Isoxazolin-3-one derivative and its preparation | |
JPS57149277A (en) | Heterocyclic compound | |
JPS5444696A (en) | Condensed isoxazole compound and its preparation | |
JPS5484597A (en) | Novel heterocyclic compound and its preparation |