SE7708901L - Antracyklinetrar och forfarande for framstellning derav - Google Patents
Antracyklinetrar och forfarande for framstellning deravInfo
- Publication number
- SE7708901L SE7708901L SE7708901A SE7708901A SE7708901L SE 7708901 L SE7708901 L SE 7708901L SE 7708901 A SE7708901 A SE 7708901A SE 7708901 A SE7708901 A SE 7708901A SE 7708901 L SE7708901 L SE 7708901L
- Authority
- SE
- Sweden
- Prior art keywords
- novel
- lower alkyl
- phenyl
- anthracyclineters
- trifluoroacetyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- JBZMHBHXHFZSMN-CWKPULSASA-N (7s,9s)-9-(2-bromoacetyl)-6,7,9,11-tetrahydroxy-4-methoxy-8,10-dihydro-7h-tetracene-5,12-dione Chemical compound C1[C@@](O)(C(=O)CBr)C[C@H](O)C2=C1C(O)=C1C(=O)C(C=CC=C3OC)=C3C(=O)C1=C2O JBZMHBHXHFZSMN-CWKPULSASA-N 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000005036 alkoxyphenyl group Chemical group 0.000 abstract 1
- 125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical class O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 abstract 1
- 125000005059 halophenyl group Chemical group 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004044 trifluoroacetyl group Chemical group FC(C(=O)*)(F)F 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7632992A GB1542162A (en) | 1977-08-02 | 1977-08-02 | Anthracycline ethers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7708901L true SE7708901L (sv) | 1978-02-08 |
Family
ID=10347059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7708901A SE7708901L (sv) | 1977-08-02 | 1977-08-04 | Antracyklinetrar och forfarande for framstellning derav |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4133877A (show.php) |
| JP (1) | JPS5321154A (show.php) |
| DE (1) | DE2735455C3 (show.php) |
| DK (1) | DK344677A (show.php) |
| FR (1) | FR2360602A1 (show.php) |
| GB (1) | GB1542162A (show.php) |
| NL (1) | NL7708530A (show.php) |
| SE (1) | SE7708901L (show.php) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1098212B (it) * | 1978-05-09 | 1985-09-07 | Farmaceutici Italia | Antracioline antitumorali sostituite |
| CA1154013A (en) * | 1979-09-01 | 1983-09-20 | Alberto Bargiotti | Antitumor glycosides, their preparation, use and compositions thereof |
| DE3641835A1 (de) * | 1986-12-08 | 1988-06-16 | Behringwerke Ag | Zytostatisch wirksame anthracyclinderivate |
| JPS63166400U (show.php) * | 1987-04-20 | 1988-10-28 | ||
| JP2779652B2 (ja) * | 1988-12-27 | 1998-07-23 | 武田薬品工業株式会社 | 生理活性物質ｔａｎ―１１２０，その還元体，それらの製造法および用途ならびに微生物 |
| GB9216962D0 (en) * | 1992-08-11 | 1992-09-23 | Erba Carlo Spa | Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives |
| GB9418260D0 (en) * | 1994-09-09 | 1994-10-26 | Erba Carlo Spa | Anthracycline derivatives |
| CN105164138B (zh) | 2013-04-29 | 2017-11-07 | 内尔维阿诺医学科学有限公司 | 新吗啉基蒽环类抗生素衍生物 |
| CN117720591A (zh) * | 2023-12-15 | 2024-03-19 | 浙江亚瑟医药有限公司 | 一种14-甲醚表柔比星的合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1457632A (en) * | 1974-03-22 | 1976-12-08 | Farmaceutici Italia | Adriamycins |
| US4039663A (en) * | 1975-03-19 | 1977-08-02 | Societa' Farmaceutici Italia S.P.A. | Daunomycins, process for their uses and intermediates |
-
1977
- 1977-07-22 US US05/817,972 patent/US4133877A/en not_active Expired - Lifetime
- 1977-08-02 GB GB7632992A patent/GB1542162A/en not_active Expired
- 1977-08-02 NL NL7708530A patent/NL7708530A/xx not_active Application Discontinuation
- 1977-08-02 FR FR7723739A patent/FR2360602A1/fr active Granted
- 1977-08-02 DK DK344677A patent/DK344677A/da not_active Application Discontinuation
- 1977-08-04 SE SE7708901A patent/SE7708901L/xx not_active Application Discontinuation
- 1977-08-05 JP JP9408377A patent/JPS5321154A/ja active Pending
- 1977-08-05 DE DE2735455A patent/DE2735455C3/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2360602B1 (show.php) | 1980-06-20 |
| DE2735455B2 (de) | 1981-10-01 |
| DK344677A (da) | 1978-02-08 |
| US4133877A (en) | 1979-01-09 |
| GB1542162A (en) | 1979-03-14 |
| DE2735455C3 (de) | 1982-10-28 |
| DE2735455A1 (de) | 1978-02-09 |
| JPS5321154A (en) | 1978-02-27 |
| NL7708530A (nl) | 1978-02-09 |
| FR2360602A1 (fr) | 1978-03-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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