SE7706275L - Substrat for bestemning av plasminogenaktivatorer - Google Patents

Substrat for bestemning av plasminogenaktivatorer

Info

Publication number
SE7706275L
SE7706275L SE7706275A SE7706275A SE7706275L SE 7706275 L SE7706275 L SE 7706275L SE 7706275 A SE7706275 A SE 7706275A SE 7706275 A SE7706275 A SE 7706275A SE 7706275 L SE7706275 L SE 7706275L
Authority
SE
Sweden
Prior art keywords
group
substrate
formula
radical
photometric
Prior art date
Application number
SE7706275A
Other languages
Unknown language ( )
English (en)
Other versions
SE444173B (sv
Inventor
L G Svendsen
Original Assignee
Pentapharm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pentapharm Ag filed Critical Pentapharm Ag
Publication of SE7706275L publication Critical patent/SE7706275L/sv
Publication of SE444173B publication Critical patent/SE444173B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/968—Plasmin, i.e. fibrinolysin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/972—Plasminogen activators
    • G01N2333/9723—Urokinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/976—Trypsin; Chymotrypsin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SE7706275A 1976-05-28 1977-05-27 Tripeptidderivat jemte anvendning av dessa for kvantitativ bestemning av proteolytiska enzymer SE444173B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH681676A CH634662A5 (de) 1976-05-28 1976-05-28 Verwendung von tripeptidderivaten zur quantitativen bestimmung von plasminogen-aktivatoren.

Publications (2)

Publication Number Publication Date
SE7706275L true SE7706275L (sv) 1977-11-29
SE444173B SE444173B (sv) 1986-03-24

Family

ID=4315468

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7706275A SE444173B (sv) 1976-05-28 1977-05-27 Tripeptidderivat jemte anvendning av dessa for kvantitativ bestemning av proteolytiska enzymer

Country Status (17)

Country Link
US (2) US4190574A (sv)
JP (1) JPS5624520B2 (sv)
AT (1) AT368550B (sv)
AU (1) AU517375B2 (sv)
BE (1) BE855085A (sv)
CA (1) CA1086614A (sv)
CH (1) CH634662A5 (sv)
DE (1) DE2724211A1 (sv)
DK (1) DK149215C (sv)
FR (1) FR2353063A1 (sv)
GB (1) GB1589738A (sv)
IL (1) IL52124A (sv)
IT (1) IT1084992B (sv)
LU (1) LU77429A1 (sv)
NL (1) NL184849C (sv)
NO (1) NO156067C (sv)
SE (1) SE444173B (sv)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5415797A (en) * 1977-06-14 1979-02-05 Seikagaku Kogyo Co Ltd Detection and measurement of toxin in cells
US4275153A (en) * 1978-08-03 1981-06-23 American Hospital Supply Corporation Analytical fluorogenic substrates for proteolytic enzymes
JPS59499B2 (ja) * 1978-11-02 1984-01-07 味の素株式会社 ペプチド誘導体
DE2903701C2 (de) * 1979-01-31 1980-10-16 Boehringer Mannheim Gmbh, 6800 Mannheim Kontrollreagens für die Bestimmung der Heparinaktivität
CA1161431A (en) * 1979-05-11 1984-01-31 Lars G. Svendsen Tripeptide derivatives
CA1161432A (en) * 1980-02-12 1984-01-31 Lars G. Svendsen Tripeptide derivatives and their application in assaying enzymes
DK155051C (da) * 1980-05-06 1989-07-03 Pentapharm Ag Tripeptidderivater samt fremgangsmaade til kvantitativ analyse for proteolytiske enzymer under anvendelse deraf
US4568636A (en) * 1981-03-25 1986-02-04 Pentapharm Ag Tripeptide derivatives
JPS57177985U (sv) * 1981-04-30 1982-11-11
DE3268329D1 (en) * 1981-11-02 1986-02-13 Pentapharm Ag Process for the quantitative determination of the blood clotting factor xii in human plasma
NL8201987A (nl) * 1982-05-13 1983-12-01 Tno Werkwijze voor het bepalen van de activiteit van plasminogeenactivator van het weefseltype, alsmede voor gebruik bij deze werkwijze geschikte combinatie van het "kit"-type.
DE3244030A1 (de) * 1982-11-27 1984-05-30 Behringwerke Ag, 3550 Marburg Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung
DK201084A (da) * 1983-04-28 1984-10-29 Kimberly Clark Co Fremgangsmaade til bestemmelse af cathepsin b i naervaerelse af andre proteolytiske enzymer, og forbindelser til anvendelse ved fremgangsmaaden
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
JPS62126196A (ja) * 1985-11-26 1987-06-08 Nitto Boseki Co Ltd 新規なα１−アンチトリプシン測定用化合物
DE3804600A1 (de) * 1988-02-13 1989-08-24 Basf Ag Mischung aus einer thrombolytisch wirkenden und einer antithrombotischen substanz
US5115099A (en) 1988-06-14 1992-05-19 Nitto Boseki Co., Ltd. Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates
CA2116786C (en) * 1991-09-18 1997-07-22 Marc D. Porter Dual-wavelength photometer and fiber-optic sensor probe
US20030207402A1 (en) * 1997-08-22 2003-11-06 Erhard Kopetzki Autocatalytically activatable zymogenic precursors of proteases and their use
KR101228239B1 (ko) * 2004-03-26 2013-01-30 디에스엠 아이피 어셋츠 비.브이. 화장품용 아릴알킬산의 아미노산 및 펩타이드 공액체

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE380258B (sv) * 1972-05-02 1975-11-03 Bofors Ab Nya diagnostiskt verksamma substrat med hog specificitet till trypsin och andra enzymer av typen peptidyl-peptid-hydrolaser
SE380257B (sv) * 1972-05-02 1975-11-03 Bofors Ab Nya diagnostiskt verksamma substrat med hog specificitet till trombin och andra proteolytiska enzymer av typen peptidyl-peptid-hydrolaser
DE2527932C2 (de) * 1974-07-02 1983-04-21 Pentapharm AG, 4052 Basel Säureadditionssalze von Tripeptidderivaten und deren Verwendung als Substrate zur Bestimmung von Plasmakallikrein
SE407058B (sv) * 1974-12-05 1979-03-12 Kabi Ab Nya kromogena enzymsubstrat for serinproteaser
CH622286A5 (sv) * 1975-06-23 1981-03-31 Pentapharm Ag
SE407571B (sv) * 1975-07-11 1979-04-02 Kabi Ab Nya kromogena enzymsubstrat for serinproteaser
US4061625A (en) * 1975-07-11 1977-12-06 Ab Kabi Novel chromogenic thrombin substrates

Also Published As

Publication number Publication date
IL52124A0 (en) 1977-07-31
CA1086614A (en) 1980-09-30
DK149215C (da) 1986-08-04
NL184849C (nl) 1989-11-16
BE855085A (fr) 1977-09-16
US4190574A (en) 1980-02-26
JPS52146694A (sv) 1977-12-06
IL52124A (en) 1980-11-30
ATA375877A (de) 1982-02-15
NO156067C (no) 1987-07-15
CH634662A5 (de) 1983-02-15
DE2724211C2 (sv) 1987-03-05
FR2353063B1 (sv) 1980-10-24
IT1084992B (it) 1985-05-28
SE444173B (sv) 1986-03-24
GB1589738A (en) 1981-05-20
AU517375B2 (en) 1981-07-30
NL7705891A (nl) 1977-11-30
AT368550B (de) 1982-10-25
DK149215B (da) 1986-03-17
LU77429A1 (sv) 1977-09-09
DE2724211A1 (de) 1977-12-01
US4278762A (en) 1981-07-14
NO156067B (no) 1987-04-06
JPS5624520B2 (sv) 1981-06-06
FR2353063A1 (fr) 1977-12-23
AU2557177A (en) 1978-11-30
NO771869L (no) 1977-11-29
DK235577A (da) 1977-11-29
NL184849B (nl) 1989-06-16

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