DK235577A - Substrat til bestemmelse af plasminogenaktivatorer - Google Patents

Substrat til bestemmelse af plasminogenaktivatorer

Info

Publication number
DK235577A
DK235577A DK235577A DK235577A DK235577A DK 235577 A DK235577 A DK 235577A DK 235577 A DK235577 A DK 235577A DK 235577 A DK235577 A DK 235577A DK 235577 A DK235577 A DK 235577A
Authority
DK
Denmark
Prior art keywords
determination
substrate
plasminogen activators
plasminogen
activators
Prior art date
Application number
DK235577A
Other languages
English (en)
Other versions
DK149215C (da
DK149215B (da
Inventor
L G Svendsen
Original Assignee
Pentapharm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pentapharm Ag filed Critical Pentapharm Ag
Publication of DK235577A publication Critical patent/DK235577A/da
Publication of DK149215B publication Critical patent/DK149215B/da
Application granted granted Critical
Publication of DK149215C publication Critical patent/DK149215C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10Anilides
    • C12Q2337/12Para-Nitroanilides p-NA
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/968Plasmin, i.e. fibrinolysin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/972Plasminogen activators
    • G01N2333/9723Urokinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974Thrombin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/976Trypsin; Chymotrypsin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK235577A 1976-05-28 1977-05-27 Tri- eller tetrapeptider eller salte deraf til anvendelse som substrat til kvantitativ bestemmelse af plasminogenaktivatorer, inhibitorer for disse og plasminogen-praeaktivatorer samt trypsin, trypsin-inhibitorer og trypsinogen i legemsvaesker hos mennesker og pattedyr og i vaevsekstraktersamt en fremgangsmaade til kvantitativ bestemmelse af plasminogenaktivato DK149215C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH681676A CH634662A5 (de) 1976-05-28 1976-05-28 Verwendung von tripeptidderivaten zur quantitativen bestimmung von plasminogen-aktivatoren.
CH681676 1976-05-28

Publications (3)

Publication Number Publication Date
DK235577A true DK235577A (da) 1977-11-29
DK149215B DK149215B (da) 1986-03-17
DK149215C DK149215C (da) 1986-08-04

Family

ID=4315468

Family Applications (1)

Application Number Title Priority Date Filing Date
DK235577A DK149215C (da) 1976-05-28 1977-05-27 Tri- eller tetrapeptider eller salte deraf til anvendelse som substrat til kvantitativ bestemmelse af plasminogenaktivatorer, inhibitorer for disse og plasminogen-praeaktivatorer samt trypsin, trypsin-inhibitorer og trypsinogen i legemsvaesker hos mennesker og pattedyr og i vaevsekstraktersamt en fremgangsmaade til kvantitativ bestemmelse af plasminogenaktivato

Country Status (17)

Country Link
US (2) US4190574A (da)
JP (1) JPS5624520B2 (da)
AT (1) AT368550B (da)
AU (1) AU517375B2 (da)
BE (1) BE855085A (da)
CA (1) CA1086614A (da)
CH (1) CH634662A5 (da)
DE (1) DE2724211A1 (da)
DK (1) DK149215C (da)
FR (1) FR2353063A1 (da)
GB (1) GB1589738A (da)
IL (1) IL52124A (da)
IT (1) IT1084992B (da)
LU (1) LU77429A1 (da)
NL (1) NL184849C (da)
NO (1) NO156067C (da)
SE (1) SE444173B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5415797A (en) * 1977-06-14 1979-02-05 Seikagaku Kogyo Co Ltd Detection and measurement of toxin in cells
US4275153A (en) * 1978-08-03 1981-06-23 American Hospital Supply Corporation Analytical fluorogenic substrates for proteolytic enzymes
JPS59499B2 (ja) * 1978-11-02 1984-01-07 味の素株式会社 ペプチド誘導体
DE2903701C2 (de) * 1979-01-31 1980-10-16 Boehringer Mannheim Gmbh, 6800 Mannheim Kontrollreagens für die Bestimmung der Heparinaktivität
CA1161431A (en) * 1979-05-11 1984-01-31 Lars G. Svendsen Tripeptide derivatives
CA1161432A (en) * 1980-02-12 1984-01-31 Lars G. Svendsen Tripeptide derivatives and their application in assaying enzymes
DK155051C (da) * 1980-05-06 1989-07-03 Pentapharm Ag Tripeptidderivater samt fremgangsmaade til kvantitativ analyse for proteolytiske enzymer under anvendelse deraf
US4568636A (en) * 1981-03-25 1986-02-04 Pentapharm Ag Tripeptide derivatives
JPS57177985U (da) * 1981-04-30 1982-11-11
EP0078764B1 (de) * 1981-11-02 1986-01-02 Pentapharm A.G. Verfahren zur quantitativen Bestimmung von Blutgerinnungsfaktor XII in Humanplasma
NL8201987A (nl) * 1982-05-13 1983-12-01 Tno Werkwijze voor het bepalen van de activiteit van plasminogeenactivator van het weefseltype, alsmede voor gebruik bij deze werkwijze geschikte combinatie van het "kit"-type.
DE3244030A1 (de) * 1982-11-27 1984-05-30 Behringwerke Ag, 3550 Marburg Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung
DK201084A (da) * 1983-04-28 1984-10-29 Kimberly Clark Co Fremgangsmaade til bestemmelse af cathepsin b i naervaerelse af andre proteolytiske enzymer, og forbindelser til anvendelse ved fremgangsmaaden
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
JPS62126196A (ja) * 1985-11-26 1987-06-08 Nitto Boseki Co Ltd 新規なα1−アンチトリプシン測定用化合物
DE3804600A1 (de) * 1988-02-13 1989-08-24 Basf Ag Mischung aus einer thrombolytisch wirkenden und einer antithrombotischen substanz
US5115099A (en) 1988-06-14 1992-05-19 Nitto Boseki Co., Ltd. Substrates for determination of enzyme activity and intermediates for synthesis of the substrates as well as process for producing the intermediates
EP0604582A1 (en) * 1991-09-18 1994-07-06 Iowa State University Research Foundation, Inc. Dual-wavelength photometer and fiber optic sensor probe
US20030207402A1 (en) * 1997-08-22 2003-11-06 Erhard Kopetzki Autocatalytically activatable zymogenic precursors of proteases and their use
CN1934080A (zh) * 2004-03-26 2007-03-21 帝斯曼知识产权资产管理有限公司 化妆用芳基烷基酸的氨基酸和肽共轭物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE380258B (sv) * 1972-05-02 1975-11-03 Bofors Ab Nya diagnostiskt verksamma substrat med hog specificitet till trypsin och andra enzymer av typen peptidyl-peptid-hydrolaser
SE380257B (sv) * 1972-05-02 1975-11-03 Bofors Ab Nya diagnostiskt verksamma substrat med hog specificitet till trombin och andra proteolytiska enzymer av typen peptidyl-peptid-hydrolaser
DE2527932C2 (de) * 1974-07-02 1983-04-21 Pentapharm AG, 4052 Basel Säureadditionssalze von Tripeptidderivaten und deren Verwendung als Substrate zur Bestimmung von Plasmakallikrein
SE407058B (sv) * 1974-12-05 1979-03-12 Kabi Ab Nya kromogena enzymsubstrat for serinproteaser
CH622286A5 (da) * 1975-06-23 1981-03-31 Pentapharm Ag
SE407571B (sv) * 1975-07-11 1979-04-02 Kabi Ab Nya kromogena enzymsubstrat for serinproteaser
US4061625A (en) * 1975-07-11 1977-12-06 Ab Kabi Novel chromogenic thrombin substrates

Also Published As

Publication number Publication date
DK149215C (da) 1986-08-04
LU77429A1 (da) 1977-09-09
AT368550B (de) 1982-10-25
NO771869L (no) 1977-11-29
SE7706275L (sv) 1977-11-29
BE855085A (fr) 1977-09-16
NO156067B (no) 1987-04-06
FR2353063B1 (da) 1980-10-24
NL184849B (nl) 1989-06-16
IL52124A (en) 1980-11-30
DK149215B (da) 1986-03-17
NL184849C (nl) 1989-11-16
CA1086614A (en) 1980-09-30
JPS5624520B2 (da) 1981-06-06
IT1084992B (it) 1985-05-28
AU517375B2 (en) 1981-07-30
FR2353063A1 (fr) 1977-12-23
NL7705891A (nl) 1977-11-30
DE2724211A1 (de) 1977-12-01
AU2557177A (en) 1978-11-30
US4190574A (en) 1980-02-26
NO156067C (no) 1987-07-15
SE444173B (sv) 1986-03-24
IL52124A0 (en) 1977-07-31
GB1589738A (en) 1981-05-20
DE2724211C2 (da) 1987-03-05
JPS52146694A (da) 1977-12-06
CH634662A5 (de) 1983-02-15
ATA375877A (de) 1982-02-15
US4278762A (en) 1981-07-14

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