ES2077624T3 - Utilizacion de 1-arilsemicarbazidas para la estabilizacion de sustratos enzimaticos, procedimientos correspondientes y preparados de diagnostico que contengan un estabilizador de este tipo. - Google Patents

Utilizacion de 1-arilsemicarbazidas para la estabilizacion de sustratos enzimaticos, procedimientos correspondientes y preparados de diagnostico que contengan un estabilizador de este tipo.

Info

Publication number
ES2077624T3
ES2077624T3 ES90123834T ES90123834T ES2077624T3 ES 2077624 T3 ES2077624 T3 ES 2077624T3 ES 90123834 T ES90123834 T ES 90123834T ES 90123834 T ES90123834 T ES 90123834T ES 2077624 T3 ES2077624 T3 ES 2077624T3
Authority
ES
Spain
Prior art keywords
type
arylsemicarbazides
stabilizer
stabilization
preparations containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90123834T
Other languages
English (en)
Inventor
Dieter Dipl Chem Dr Mangold
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2077624T3 publication Critical patent/ES2077624T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/40—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/805—Test papers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PARA ESTABILIZACION DE SUBSTRATOS DE ENZIMAS. PROCEDIMIENTO CORRESPONDIENTE PARA OBTENER 1-ARILOSEMICARBAZIDA Y EL MEDIO QUE CONTIENE EL ESTABILIZADOR. LA INVENCION DESCRIBE SOBRE LA APLICACION DE UNOS 1-ARILOSEMICARBAZIDAS DE FORMULA (I) PARA ESTABILIZAR UNOS SUBSTRATOS DE ENZIMAS QUE SE PUEDEN FORMAR A TRAVES DE HIDROLISIS ENZIMATICA UN LEUCOCOLORANTE, QUE SE TRANSFORMA POR MEDIO DE UN ELEMENTO OXIDANTE. TRATA DE UN PROCEDIMIENTO DE ESTABILIZACION Y SE REFIERE A UN MEDIO CONTENIENDO UN ESTABILIZADOR.
ES90123834T 1989-12-21 1990-12-11 Utilizacion de 1-arilsemicarbazidas para la estabilizacion de sustratos enzimaticos, procedimientos correspondientes y preparados de diagnostico que contengan un estabilizador de este tipo. Expired - Lifetime ES2077624T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3942356A DE3942356A1 (de) 1989-12-21 1989-12-21 Verwendung von 1-arylsemicarbaziden zur stabilisierung von enzymsubstraten, entsprechende verfahren und diagnostisches mittel enthaltend einen solchen stabilisator

Publications (1)

Publication Number Publication Date
ES2077624T3 true ES2077624T3 (es) 1995-12-01

Family

ID=6396067

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90123834T Expired - Lifetime ES2077624T3 (es) 1989-12-21 1990-12-11 Utilizacion de 1-arilsemicarbazidas para la estabilizacion de sustratos enzimaticos, procedimientos correspondientes y preparados de diagnostico que contengan un estabilizador de este tipo.

Country Status (6)

Country Link
US (1) US5391482A (es)
EP (1) EP0433853B1 (es)
JP (1) JPH0771516B2 (es)
AT (1) ATE126542T1 (es)
DE (2) DE3942356A1 (es)
ES (1) ES2077624T3 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3942355A1 (de) * 1989-12-21 1991-06-27 Boehringer Mannheim Gmbh N- und o-substituierte aminophenolderivate, zwischenprodukte zu deren herstellung, deren verwendung als hydrolasesubstrate, ein entsprechendes bestimmungsverfahren und hierfuer geeignetes diagnostisches mittel
US5316906A (en) * 1991-08-23 1994-05-31 Molecular Probes, Inc. Enzymatic analysis using substrates that yield fluorescent precipitates
FR2742162B1 (fr) * 1995-12-06 1998-01-16 Oreal Procede de preparation de composes indoliques
US5783407A (en) * 1996-04-05 1998-07-21 Beckman Instruments, Inc. Method of measuring bilirubin
TWI312347B (en) 2001-02-08 2009-07-21 Eisai R&D Man Co Ltd Bicyclic nitrogen-containing condensed ring compounds
AU2002251546B2 (en) 2001-04-27 2007-01-18 Eisai R & D Management Co., Ltd. Pyrazolo[1,5-A]pyridines and medicines containing the same
JP2004029416A (ja) 2002-06-26 2004-01-29 Dainippon Screen Mfg Co Ltd 光走査装置
DK1555265T3 (da) 2002-10-22 2009-06-22 Eisai R&D Man Co Ltd 7-phenylpyrazolopyridin-forbindelser
US7176216B2 (en) 2002-10-22 2007-02-13 Eisai Co., Ltd. 7-phenylpyrazolopyridine compounds
US20110172767A1 (en) * 2006-04-19 2011-07-14 Pankaj Rathi Minimally invasive, direct delivery methods for implanting obesity treatment devices
US20080057596A1 (en) * 2006-08-30 2008-03-06 Wai Tak Law Colorimetric determination of somatic cell count in milk
KR101601994B1 (ko) 2008-04-15 2016-03-17 에자이 알앤드디 매니지먼트 가부시키가이샤 3-페닐피라졸로[5,1-ｂ]티아졸 화합물
DE102008057471B3 (de) * 2008-11-14 2010-05-06 Axagarius Gmbh & Co. Kg Vorrichtung zur Bestimmung des Gesamtchlorgehaltes in einer Flüssigkeit
EP2487177A1 (en) * 2009-10-08 2012-08-15 Eisai R&D Management Co., Ltd. Pyrazoloxazole compound
AR078521A1 (es) 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716060C3 (de) * 1977-04-09 1980-06-12 Boehringer Mannheim Gmbh, 6800 Mannheim Stabilisierte Schnelldiagnostica mit Oxydationsindikatoren
DE3005845A1 (de) * 1980-02-16 1981-09-03 Boehringer Mannheim Gmbh, 6800 Mannheim Aminosaeure- und peptidester von leuko-indoanilinen, verfahren zu deren herstellung sowie diese verbindungen enthaltende mittel zum nachweis proteolytischer enzyme
DE3644401A1 (de) * 1986-12-24 1988-07-07 Boehringer Mannheim Gmbh Neue hydrolase-substrate
JPH0631294B2 (ja) * 1988-12-29 1994-04-27 日東紡績株式会社 新規グルコサミン誘導体、これを用いる酵素活性測定試薬及び酵素活性測定方法
US4859607A (en) * 1989-01-17 1989-08-22 Kansas State University Research Foundation Colorimetric detector for ozone and method of preparation
US5116729A (en) * 1989-03-10 1992-05-26 Miles Inc. Stabilization of oxidase enzyme-based test strips

Also Published As

Publication number Publication date
US5391482A (en) 1995-02-21
ATE126542T1 (de) 1995-09-15
EP0433853A1 (de) 1991-06-26
DE3942356A1 (de) 1991-06-27
EP0433853B1 (de) 1995-08-16
JPH06217796A (ja) 1994-08-09
DE59009532D1 (de) 1995-09-21
JPH0771516B2 (ja) 1995-08-02

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