SE7607727L - ACID TRANSPORTING EMULSION - Google Patents
ACID TRANSPORTING EMULSIONInfo
- Publication number
- SE7607727L SE7607727L SE7607727A SE7607727A SE7607727L SE 7607727 L SE7607727 L SE 7607727L SE 7607727 A SE7607727 A SE 7607727A SE 7607727 A SE7607727 A SE 7607727A SE 7607727 L SE7607727 L SE 7607727L
- Authority
- SE
- Sweden
- Prior art keywords
- carbon atoms
- perfluoro
- alkyl
- emulsion
- weight
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Abstract
The stable emulsion contains the following components: (A) At least one perfluorocarbon compound which contains 9 to 11 carbon atoms, selected from the series comprising perfluorodecalin, perfluoromethyldecalin, perfluoroalkylcyclohexane having 3 to 5 carbon atoms in the alkyl, perfluoroalkyltetrahydrofuran having 5 to 7 carbon atoms in the alkyl, perfluoroalkyltetrahydropyran having 4 to 6 carbon atoms in the alkyl and perfluoroalkanes having 9 to 11 carbon atoms; (B) At least one perfluoro-tertiary-amine having 9 to 11 carbon atoms, selected from the series comprising perfluoro-tertiaryalkylamines having 9 to 11 carbon atoms, perfluoro-N-alkylpiperidines having 4 to 6 carbon atoms in the alkyl and perfluoro-N-alkylmorpholines having 5 to 7 carbon atoms in the alkyl; a high-molecular-weight, non-ionic surfactant having a molecular weight of 2,000 to 20,000; a phospholipoid; at least one fatty acid having 8 to 22 carbon atoms or its physiologically acceptable salt or monoglyceride; the ratio by weight of the perfluorocarbon compound (A) to the perfluoro-tertiary-amine (B) being 95-50:5-50. Such an emulsion is stable even upon prolonged storage.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65496476A | 1976-02-03 | 1976-02-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7607727L true SE7607727L (en) | 1977-08-04 |
| SE442706B SE442706B (en) | 1986-01-27 |
Family
ID=24626936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7607727A SE442706B (en) | 1976-02-03 | 1976-07-06 | PROCEDURE FOR PREPARING AN ACID TRANSPORTING EMULSION |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5835485B2 (en) |
| AR (1) | AR218864A1 (en) |
| AT (1) | AT355214B (en) |
| BE (1) | BE850992A (en) |
| CA (1) | CA1072446A (en) |
| CH (1) | CH633674A5 (en) |
| DD (1) | DD132231A5 (en) |
| DE (1) | DE2630586C2 (en) |
| DK (1) | DK152256C (en) |
| ES (1) | ES449635A1 (en) |
| FI (1) | FI58071C (en) |
| FR (1) | FR2361867A1 (en) |
| GB (1) | GB1549038A (en) |
| IL (1) | IL51325A (en) |
| LU (1) | LU76698A1 (en) |
| MX (1) | MX4136E (en) |
| NL (1) | NL171533C (en) |
| NO (1) | NO145370C (en) |
| NZ (1) | NZ183096A (en) |
| SE (1) | SE442706B (en) |
| SU (1) | SU797546A3 (en) |
| ZA (1) | ZA77229B (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4186253A (en) * | 1978-10-10 | 1980-01-29 | The Green Cross Corporation | Perfusate for preserving organ to be transplanted and preserving method |
| JPS55100312A (en) * | 1979-01-25 | 1980-07-31 | Toshiro Wada | Contrast medium for blood vessel |
| EP0077114B1 (en) * | 1981-09-08 | 1987-12-02 | Green Cross Corporation | Perfluorochemicals, process for preparing the same and their use as blood substitutes |
| US4423077A (en) * | 1982-07-27 | 1983-12-27 | The University Of Pennsylvania | Perfluorochemical emulsion artificial blood |
| JPS5946218A (en) * | 1982-09-09 | 1984-03-15 | Green Cross Corp:The | Fluorocarbon emulsion preparation |
| JPS59175421A (en) * | 1983-03-24 | 1984-10-04 | Tetsuzou Agishi | Hemocathartic agent |
| EP0663821A4 (en) * | 1991-08-08 | 1997-09-17 | Leigh D Segel | Fluorocarbon blood substitute. |
| US5658962A (en) | 1994-05-20 | 1997-08-19 | Minnesota Mining And Manufacturing Company | Omega-hydrofluoroalkyl ethers, precursor carboxylic acids and derivatives thereof, and their preparation and application |
| US5502094A (en) * | 1994-05-20 | 1996-03-26 | Minnesota Mining And Manufacturing Company | Physiologically acceptable emulsions containing perfluorocarbon ether hydrides and methods for use |
| WO1997025978A1 (en) * | 1996-01-15 | 1997-07-24 | BELOYARTSEV, Arkady Felixovich | Method of obtaining perfluorocarbon emulsions for medical purposes |
| CN1068778C (en) * | 1998-05-15 | 2001-07-25 | 赵超英 | Novel drug composition for treating and curing and its preparing method |
| US7357937B2 (en) | 2002-09-24 | 2008-04-15 | Therox, Inc. | Perfluorocarbon emulsions with non-fluorinated surfactants |
| RU2259819C1 (en) | 2004-03-01 | 2005-09-10 | Кузнецова Ирина Николаевна | Emulsion of perfluoroorganic compounds of medicinal indication and method for its obtaining |
| MX2008011745A (en) | 2006-03-14 | 2008-11-25 | Sergey Ivanovich Vorobyev | Perfluorocarbon gas transferring emulsion for medico-biological use, the composition and the production method thereof a medicinal agent. |
| US8063020B2 (en) * | 2007-12-22 | 2011-11-22 | Simpkins Cuthbert O | Resuscitation fluid |
| GB2467353B (en) * | 2009-01-30 | 2011-07-20 | Steven Skill | Apparatus for treatment of fluid streams and method of conducting the same |
| ES2541226B2 (en) * | 2014-01-15 | 2016-02-12 | MONDRAGÓN GOI ESKOLA POLITEKNIKOA J. Mª. ARIZMENDIARRIETA, S.C | Blood phantom |
| RU2745290C2 (en) * | 2019-04-12 | 2021-03-23 | Ирина Николаевна Кузнецова | Emulsion of perfluorocarbon compounds for biomedical purposes and a method for its production |
| WO2024046999A1 (en) * | 2022-08-31 | 2024-03-07 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Lecithin-modified nanoscale oxygen carriers (lenox) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH604490A5 (en) * | 1970-09-05 | 1978-09-15 | Green Cross Corp | |
| JPS5331209B2 (en) * | 1973-10-05 | 1978-09-01 |
-
1976
- 1976-07-01 JP JP51078127A patent/JPS5835485B2/en not_active Expired
- 1976-07-02 GB GB27739/76A patent/GB1549038A/en not_active Expired
- 1976-07-06 SE SE7607727A patent/SE442706B/en not_active IP Right Cessation
- 1976-07-07 AT AT496676A patent/AT355214B/en not_active IP Right Cessation
- 1976-07-07 DK DK307276A patent/DK152256C/en not_active IP Right Cessation
- 1976-07-07 ES ES449635A patent/ES449635A1/en not_active Expired
- 1976-07-07 NL NLAANVRAGE7607514,A patent/NL171533C/en not_active IP Right Cessation
- 1976-07-07 DE DE2630586A patent/DE2630586C2/en not_active Expired
- 1976-07-07 CH CH869676A patent/CH633674A5/en not_active IP Right Cessation
- 1976-07-08 FR FR7620907A patent/FR2361867A1/en active Granted
- 1976-07-08 CA CA256,571A patent/CA1072446A/en not_active Expired
-
1977
- 1977-01-17 NZ NZ183096A patent/NZ183096A/en unknown
- 1977-01-17 ZA ZA770229A patent/ZA77229B/en unknown
- 1977-01-21 MX MX775377U patent/MX4136E/en unknown
- 1977-01-25 IL IL51325A patent/IL51325A/en unknown
- 1977-01-31 AR AR266381A patent/AR218864A1/en active
- 1977-02-01 NO NO770324A patent/NO145370C/en unknown
- 1977-02-01 FI FI770354A patent/FI58071C/en not_active IP Right Cessation
- 1977-02-02 SU SU772447657A patent/SU797546A3/en active
- 1977-02-02 BE BE174577A patent/BE850992A/en not_active IP Right Cessation
- 1977-02-03 DD DD7700197227A patent/DD132231A5/en unknown
- 1977-02-03 LU LU76698A patent/LU76698A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO770324L (en) | 1977-08-04 |
| NZ183096A (en) | 1979-04-26 |
| GB1549038A (en) | 1979-08-01 |
| SE442706B (en) | 1986-01-27 |
| FR2361867A1 (en) | 1978-03-17 |
| IL51325A0 (en) | 1977-03-31 |
| DE2630586A1 (en) | 1977-08-11 |
| BE850992A (en) | 1977-05-31 |
| DK152256C (en) | 1988-08-29 |
| FI770354A (en) | 1977-08-04 |
| AR218864A1 (en) | 1980-07-15 |
| ATA496676A (en) | 1979-07-15 |
| DK152256B (en) | 1988-02-15 |
| LU76698A1 (en) | 1977-06-28 |
| NL171533C (en) | 1983-04-18 |
| DD132231A5 (en) | 1978-09-13 |
| NO145370C (en) | 1982-03-10 |
| FR2361867B1 (en) | 1978-12-15 |
| AU1550576A (en) | 1977-07-28 |
| JPS5296722A (en) | 1977-08-13 |
| MX4136E (en) | 1982-01-06 |
| SU797546A3 (en) | 1981-01-15 |
| NO145370B (en) | 1981-11-30 |
| DK307276A (en) | 1977-08-04 |
| CH633674A5 (en) | 1982-12-31 |
| ZA77229B (en) | 1977-11-30 |
| DE2630586C2 (en) | 1984-06-07 |
| NL171533B (en) | 1982-11-16 |
| FI58071C (en) | 1980-12-10 |
| ES449635A1 (en) | 1977-11-16 |
| CA1072446A (en) | 1980-02-26 |
| IL51325A (en) | 1980-05-30 |
| JPS5835485B2 (en) | 1983-08-03 |
| FI58071B (en) | 1980-08-29 |
| AT355214B (en) | 1980-02-25 |
| NL7607514A (en) | 1977-08-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 7607727-0 Effective date: 19950210 Format of ref document f/p: F |
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